|
GB1570494A
(en)
*
|
1975-11-28 |
1980-07-02 |
Ici Ltd |
Thienopyrimidine derivatives and their use as pesticides
|
|
US5280026A
(en)
*
|
1989-05-30 |
1994-01-18 |
Smithkline Beecham Intercredit B.V. |
Thienopyrimidines
|
|
GB8912335D0
(en)
*
|
1989-05-30 |
1989-07-12 |
Smithkline Beckman Intercredit |
Compounds
|
|
US5098902A
(en)
*
|
1991-03-18 |
1992-03-24 |
Warner-Lambert Company |
Method of treating neurodegenerative diseases
|
|
US6187777B1
(en)
|
1998-02-06 |
2001-02-13 |
Amgen Inc. |
Compounds and methods which modulate feeding behavior and related diseases
|
|
US6608053B2
(en)
*
|
2000-04-27 |
2003-08-19 |
Yamanouchi Pharmaceutical Co., Ltd. |
Fused heteroaryl derivatives
|
|
GB0423653D0
(en)
*
|
2004-10-25 |
2004-11-24 |
Piramed Ltd |
Pharmaceutical compounds
|
|
CN101163706A
(zh)
*
|
2005-04-21 |
2008-04-16 |
贝林格尔·英格海姆国际有限公司 |
用于治疗炎性疾病的二氢噻吩并嘧啶
|
|
EP1847543A1
(de)
|
2006-04-19 |
2007-10-24 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
|
|
PL2041139T3
(pl)
|
2006-04-26 |
2012-05-31 |
Hoffmann La Roche |
Związki farmaceutyczne
|
|
KR101533461B1
(ko)
|
2006-04-26 |
2015-07-02 |
에프. 호프만-라 로슈 아게 |
Pi3k저해제로 유용한 티에노[3,2-d]피리미딘 유도체
|
|
MX2008013583A
(es)
|
2006-04-26 |
2008-10-31 |
Genentech Inc |
Compuestos del inhibidor de fosfoinositido 3-cinasa y composiciones farmaceuticas que los contienen.
|
|
AR064154A1
(es)
*
|
2006-12-07 |
2009-03-18 |
Piramed Ltd |
Compuestos inhibidores de fodfoinostida 3- quinasas y composiciones farmaceuticas
|
|
PE20081679A1
(es)
|
2006-12-07 |
2008-12-18 |
Hoffmann La Roche |
Compuestos del inhibidor de fosfoinositida 3-cinasa y metodos de uso
|
|
JP5736171B2
(ja)
|
2007-09-24 |
2015-06-17 |
ジェネンテック, インコーポレイテッド |
チアゾロピリミジンpi3k阻害剤化合物および使用方法
|
|
ES2524910T3
(es)
*
|
2007-10-19 |
2014-12-15 |
Boehringer Ingelheim International Gmbh |
Piperidino-dihidrotienopirimidinas sustituidas
|
|
ATE537175T1
(de)
|
2007-10-19 |
2011-12-15 |
Boehringer Ingelheim Int |
Neue piperazino-dihydrothienopyrimidin-derivate
|
|
JP5341899B2
(ja)
|
2007-10-19 |
2013-11-13 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
ヘテロ環置換ピペラジノ−ジヒドロチエノピリミジン
|
|
EP2214675B1
(en)
|
2007-10-25 |
2013-11-20 |
Genentech, Inc. |
Process for making thienopyrimidine compounds
|
|
GB0721095D0
(en)
*
|
2007-10-26 |
2007-12-05 |
Piramed Ltd |
Pharmaceutical compounds
|
|
BRPI1006189A2
(pt)
|
2009-03-12 |
2020-08-18 |
Genentech Inc |
uso de uma combinação terapêutica, formulação farmacêutica, artigo de manufatura, produto, método para determinar compostos a serem utilizados em combinação para o tratamento de uma malignidade hematopoiética e método para selecionar compostos a serem utilizados em combinação para o tratamento de câncer
|
|
WO2010136491A1
(en)
*
|
2009-05-27 |
2010-12-02 |
F. Hoffmann-La Roche Ag |
Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
|
|
US8173650B2
(en)
|
2009-05-27 |
2012-05-08 |
Genentech, Inc. |
Bicyclic pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use
|
|
US20110086837A1
(en)
*
|
2009-10-12 |
2011-04-14 |
Genentech, Inc. |
Combinations of a pi3k inhibitor and a mek inhibitor
|
|
CN103038643A
(zh)
|
2010-04-16 |
2013-04-10 |
基因泰克公司 |
作为pi3k/akt激酶途径抑制剂效能的预测性生物标记的foxo3a
|
|
WO2012088254A1
(en)
|
2010-12-22 |
2012-06-28 |
Genentech, Inc. |
Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
|
|
US20130059866A1
(en)
|
2011-08-24 |
2013-03-07 |
Boehringer Ingelheim International Gmbh |
Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
|
|
US9802954B2
(en)
|
2011-08-24 |
2017-10-31 |
Boehringer Ingelheim International Gmbh |
Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
|
|
WO2014130923A2
(en)
|
2013-02-25 |
2014-08-28 |
Genentech, Inc. |
Methods and compositions for detecting and treating drug resistant akt mutant
|
|
KR102903997B1
(ko)
*
|
2018-10-01 |
2025-12-26 |
젠자임 코포레이션 |
UDP 글리코실트랜스퍼라제 억제제로서의 티에노[3,2-b]피리딘 유도체 및 사용 방법
|
|
GB202014736D0
(en)
*
|
2020-09-18 |
2020-11-04 |
Imperial College Innovations Ltd |
Novel compounds and their use in therapy
|