NL6413349A - - Google Patents

Info

Publication number
NL6413349A
NL6413349A NL6413349A NL6413349A NL6413349A NL 6413349 A NL6413349 A NL 6413349A NL 6413349 A NL6413349 A NL 6413349A NL 6413349 A NL6413349 A NL 6413349A NL 6413349 A NL6413349 A NL 6413349A
Authority
NL
Netherlands
Application number
NL6413349A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL6413349A publication Critical patent/NL6413349A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL6413349A 1963-11-19 1964-11-17 NL6413349A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB45685/63A GB1101425A (en) 1963-11-19 1963-11-19 New pyrimidine derivatives

Publications (1)

Publication Number Publication Date
NL6413349A true NL6413349A (fr) 1965-05-20

Family

ID=10438157

Family Applications (2)

Application Number Title Priority Date Filing Date
NL127996D NL127996C (fr) 1963-11-19
NL6413349A NL6413349A (fr) 1963-11-19 1964-11-17

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NL127996D NL127996C (fr) 1963-11-19

Country Status (14)

Country Link
US (1) US3299067A (fr)
AT (1) AT255421B (fr)
BE (1) BE655431A (fr)
BR (1) BR6464358D0 (fr)
CH (1) CH437310A (fr)
DE (1) DE1297610B (fr)
DK (1) DK115995B (fr)
ES (1) ES306226A1 (fr)
FI (1) FI46163C (fr)
FR (1) FR4770M (fr)
GB (1) GB1101425A (fr)
NL (2) NL6413349A (fr)
NO (1) NO115800B (fr)
SE (1) SE322521B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999016746A1 (fr) * 1997-09-29 1999-04-08 Aventis Pharmaceuticals Inc. Derives d'amino-alkylphenols et composes associes
CN107417674A (zh) * 2017-06-26 2017-12-01 苏州弘森药业股份有限公司 一种吡贝地尔的提纯方法

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3980781A (en) * 1966-03-31 1976-09-14 Imperial Chemical Industries Limited Fungicidal composition and method containing 2-amino-pyrimidines
GB1143167A (en) * 1967-01-25 1969-02-19 Ucb Sa Derivatives of pyrimidine
GB1369379A (en) * 1972-04-07 1974-10-09 Science Union & Cie Benzodioxole derivatives and processes for preparing them
US3919230A (en) * 1974-02-07 1975-11-11 Smithkline Corp {62 -Naphthylmethyl piperazinyl derivatives
US3988457A (en) * 1974-02-07 1976-10-26 Smithkline Corporation Novel compounds and compositions for treating Parkinson's disease
US3960863A (en) * 1974-06-25 1976-06-01 Sankyo Company Limited Pyrido[1,2-a]pyrimidinone derivatives
US4166852A (en) * 1974-08-09 1979-09-04 Produits Chimiques Ugine Kuhlmann Piperazino-pyrimidines and their use as spasmolytic agents
OA06083A (fr) * 1977-11-09 1981-06-30 Science Union & Cie Ste Franca Nouvelles pipérazines disubstituées, leurs procédés de préparation et les compositions pharmaceutiques les renfermant.
FR2519986A1 (fr) * 1982-01-21 1983-07-22 Adir Nouveaux derives de benzodioxine, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
FR2539990A1 (fr) * 1983-01-28 1984-08-03 Sanofi Sa Composition pharmaceutique a action psychotrope dopaminergique contenant une 2-piperazinopyrimidine
US4605655A (en) * 1984-03-06 1986-08-12 Bristol-Myers Company Antipsychotic 1-fluorophenylbutyl-4-(2-pyrimidinyl)piperazine derivatives
US4980350A (en) * 1988-02-25 1990-12-25 Merck & Co., Inc. Piperazinylalkylpyrimidines as hypoglycemic agents
EP0330263A1 (fr) * 1988-02-25 1989-08-30 Merck & Co. Inc. Pipérazinylalkylpyrimidines comme agents hypoglycémiques
US4994460A (en) * 1989-06-01 1991-02-19 Bristol-Myers Squibb Co. Agents for treatment of brain ischemia
US5859246A (en) * 1997-01-30 1999-01-12 Neurogen Corporation 1-phenyl-4-benzylpiperazines: dopamine receptor subtype specific ligands
US6825198B2 (en) * 2001-06-21 2004-11-30 Pfizer Inc 5-HT receptor ligands and uses thereof
AP2005003232A0 (en) 2002-08-19 2005-03-31 Pfizer Prod Inc Combination therapy for hyperproliferative diseases.
RU2006129469A (ru) * 2004-01-16 2008-02-27 Новартис АГ (CH) 2, 4-диаминопиримидины и их применение для индукции кардиомиогенеза
US7241891B2 (en) * 2004-03-29 2007-07-10 Chung-Shan Institute Of Science & Technology Method for the purification of Piribedil
US20060063803A1 (en) * 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
ES2382009T3 (es) 2006-12-01 2012-06-04 Bristol-Myers Squibb Company Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares
CN101735201B (zh) * 2009-12-17 2012-05-30 宁夏康亚药业有限公司 一种吡贝地尔的制备方法
CN101830891A (zh) * 2010-05-18 2010-09-15 沈阳药科大学 一种吡贝地尔的制备方法
CN105143203A (zh) 2013-04-17 2015-12-09 辉瑞大药厂 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物
MA53944A (fr) 2014-08-28 2021-08-25 Asceneuron Sa Inhibiteurs de la glycosidase
WO2016055901A1 (fr) 2014-10-08 2016-04-14 Pfizer Inc. Composés d'amide substitué
WO2017144639A1 (fr) 2016-02-25 2017-08-31 Asceneuron S. A. Inhibiteurs de glycosidases
EP3419971B1 (fr) 2016-02-25 2022-04-20 Asceneuron SA Inhibiteurs de glycosidases
EP3585783A2 (fr) 2016-02-25 2020-01-01 Asceneuron SA Inhibiteurs de la sulfoximine glycosidase
US11261183B2 (en) 2016-02-25 2022-03-01 Asceneuron Sa Sulfoximine glycosidase inhibitors
ES2879351T3 (es) 2016-02-25 2021-11-22 Asceneuron Sa Sales de derivados de piperazina obtenidas por adición de ácidos
CN106432212B (zh) * 2016-09-21 2019-01-11 苏州弘森药业股份有限公司 一种合成吡贝地尔的方法
CN107163032A (zh) * 2017-06-19 2017-09-15 太仓卡斯特姆新材料有限公司 一种高收率的吡贝地尔制备方法
CN107216318A (zh) * 2017-06-19 2017-09-29 太仓弘杉环保科技有限公司 一种吡贝地尔制备方法
CN107266429A (zh) * 2017-06-19 2017-10-20 太仓大唐化纤厂 一种高品质的吡贝地尔制备方法
WO2019037860A1 (fr) 2017-08-24 2019-02-28 Asceneuron S.A. Inhibiteurs linéaires de la glycosidase
WO2019037861A1 (fr) 2017-08-24 2019-02-28 Asceneuron S.A. Inhibiteurs de glycosidases annelés
RU2737721C2 (ru) * 2017-12-15 2020-12-02 Алексей Георгиевич Александров Способ получения фармацевтической субстанции на основе пирибедила
US12016852B2 (en) 2018-08-22 2024-06-25 Asceneuron Sa Pyrrolidine glycosidase inhibitors
WO2020039029A1 (fr) 2018-08-22 2020-02-27 Asceneuron S. A. Composés spiro utilisés en tant qu'inhibiteurs de glycosidases
WO2020039028A1 (fr) 2018-08-22 2020-02-27 Asceneuron S. A. Inhibiteurs de tétrahydro-benzoazépine glycosidase
WO2020150473A2 (fr) 2019-01-18 2020-07-23 Dogma Therapeutics, Inc. Inhibiteurs de pcsk9 et leurs procédés d'utilisation
US20220143042A1 (en) 2019-02-22 2022-05-12 Asceneuron Sa Fused glycosidase inhibitors

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL72956C (fr) * 1947-11-12
DE942029C (de) * 1951-06-22 1956-04-26 American Cyanamid Co Verfahren zur Herstellung von neuen, in 1-Stellung substituierten 4-Aminopiperazinderivaten
US3078214A (en) * 1958-09-12 1963-02-19 Sandoz Ag Treatment of mental disturbances with esters of indoles
US2985657A (en) * 1959-10-12 1961-05-23 Paul A J Janssen 1-(aroylalkyl)-4-heterocyclylpiperazines
US2979508A (en) * 1959-10-12 1961-04-11 Paul A J Janssen Heterocyclic derivatives of 1-phenyl-omega-(piperazine) alkanols
US3141820A (en) * 1960-10-31 1964-07-21 Merck & Co Inc Coccidiosis control composition
BE618035A (fr) * 1961-05-26
US3144387A (en) * 1961-06-30 1964-08-11 Parke Davis & Co Anti-inflammatory compositions

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999016746A1 (fr) * 1997-09-29 1999-04-08 Aventis Pharmaceuticals Inc. Derives d'amino-alkylphenols et composes associes
CN107417674A (zh) * 2017-06-26 2017-12-01 苏州弘森药业股份有限公司 一种吡贝地尔的提纯方法
CN107417674B (zh) * 2017-06-26 2020-12-29 苏州弘森药业股份有限公司 一种吡贝地尔的提纯方法

Also Published As

Publication number Publication date
NL127996C (fr)
US3299067A (en) 1967-01-17
FI46163C (fi) 1973-01-10
ES306226A1 (es) 1965-03-01
BE655431A (fr) 1965-05-06
AT255421B (de) 1967-07-10
FI46163B (fr) 1972-10-02
NO115800B (fr) 1968-12-09
DE1297610B (de) 1969-06-19
DK115995B (da) 1969-12-01
SE322521B (fr) 1970-04-13
CH437310A (fr) 1967-06-15
BR6464358D0 (pt) 1973-07-26
FR4770M (fr) 1967-01-23
GB1101425A (en) 1968-01-31

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