NL6404490A - - Google Patents
Info
- Publication number
- NL6404490A NL6404490A NL6404490A NL6404490A NL6404490A NL 6404490 A NL6404490 A NL 6404490A NL 6404490 A NL6404490 A NL 6404490A NL 6404490 A NL6404490 A NL 6404490A NL 6404490 A NL6404490 A NL 6404490A
- Authority
- NL
- Netherlands
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Glass Melting And Manufacturing (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27523763A | 1963-04-24 | 1963-04-24 | |
US330263A US3326924A (en) | 1963-04-24 | 1963-12-13 | Novel aza-dibenzo[a, d]-cycloheptene derivatives |
US330244A US3366635A (en) | 1963-04-24 | 1963-12-13 | Aza-5h-dibenzo-[a,d]-(cycloheptenes and cycloheptene-5-ones) and the corresponding 10, 11-dihydro derivatives thereof |
US42010164A | 1964-12-21 | 1964-12-21 | |
US580169A US3357986A (en) | 1963-04-24 | 1966-09-19 | 1, 2, 3 or 4, aza,-[5-piperdyl or hydrocarbyl amino]-10, 11 dihydro-5h-dibenzo-[a, d]-cycloheptene |
Publications (1)
Publication Number | Publication Date |
---|---|
NL6404490A true NL6404490A (cs) | 1964-10-26 |
Family
ID=27540590
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL132137D NL132137C (cs) | 1963-04-24 | ||
NL6404490A NL6404490A (cs) | 1963-04-24 | 1964-04-23 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL132137D NL132137C (cs) | 1963-04-24 |
Country Status (17)
Country | Link |
---|---|
US (3) | US3366635A (cs) |
JP (3) | JPS4840356B1 (cs) |
BE (1) | BE647043A (cs) |
BR (1) | BR6458580D0 (cs) |
CH (2) | CH535769A (cs) |
CY (1) | CY543A (cs) |
DE (2) | DE1795744A1 (cs) |
DK (2) | DK125421B (cs) |
FI (1) | FI52220C (cs) |
FR (1) | FR4013M (cs) |
GB (1) | GB1065191A (cs) |
IL (1) | IL21208A (cs) |
IT (2) | IT1149233B (cs) |
MY (1) | MY7000130A (cs) |
NL (2) | NL6404490A (cs) |
NO (3) | NO120935B (cs) |
SE (4) | SE379765B (cs) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3378567A (en) * | 1965-12-20 | 1968-04-16 | Schering Corp | 5-diloweralkylaminoalkoxy ethers of 4-aza-10, 11-dihydro-5h-dibenzo[a, d]-cycloheptene derivatives |
US3409621A (en) * | 1966-04-01 | 1968-11-05 | Schering Corp | Piperazino-aza-dibenzo-[a, d]-cycloheptenes |
US3458522A (en) * | 1967-05-17 | 1969-07-29 | Sandoz Ag | 4-piperidine substituted benzocycloheptaoxazoles and benzocycloheptathiazoles |
US3458524A (en) * | 1968-03-27 | 1969-07-29 | Schering Corp | Novel 5-alkylaminoalkoximino-aza-dibenzo-(a,d)-cycloheptenes |
DE2640022A1 (de) * | 1975-09-15 | 1977-03-24 | Sandoz Ag | Neue organische verbindungen, ihre herstellung und verwendung |
US4092322A (en) * | 1977-02-14 | 1978-05-30 | Warner-Lambert Company | 1-Benzoxepino[4,3-c]pyridines |
US4282233B1 (en) * | 1980-06-19 | 2000-09-05 | Schering Corp | Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines |
US4355036A (en) * | 1980-06-19 | 1982-10-19 | Schering Corporation | Tricyclic-substituted piperidine antihistamines |
US4454143A (en) * | 1981-03-16 | 1984-06-12 | Schering Corporation | Tricyclic antihistamines |
JPS61501205A (ja) * | 1984-02-15 | 1986-06-19 | シェリング・コ−ポレ−ション | 8↓−クロル↓−6,11↓−ジヒドロ↓−11↓−(4↓−ピペリジリデン)↓−5H↓−ベンゾ〔5,6〕シクロヘプタ〔1,2−b〕ピリジンおよびその塩、これらの化合物の製造方法、ならびにこれらの化合物を含有する医薬組成物 |
US4834980A (en) * | 1984-07-23 | 1989-05-30 | Schering Corporation | Transdermal delivery of azatidine |
EP0208855B1 (en) * | 1985-05-13 | 1991-03-06 | Schering Corporation | process for preparing piperidylidene dihydrodibenzo(a,d)cycloheptenes and aza derivatives thereof, compounds obtained by such process and the use of such compounds for preparing useful pharmaceutical compositions |
US4731447A (en) * | 1985-05-13 | 1988-03-15 | Schering Corporation | Process for preparing piperidylidene dihydro-dibenzo(a,d)-cycloheptenes or aza-derivatives thereof |
US4804666A (en) * | 1985-08-14 | 1989-02-14 | Schering Corporation | Antiallergic 6,11-dihydro-11-(4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines |
US4639457A (en) * | 1985-08-19 | 1987-01-27 | Merck & Co., Inc. | Benzocycloheptapyridone compounds for treating congestive heart failure |
US4873335A (en) * | 1986-03-12 | 1989-10-10 | Schering Corporation | 3-phenethyl-2-benzene-amides or aza-derivatives thereof |
US5011860A (en) * | 1986-04-11 | 1991-04-30 | Schering Corporation | Aryl-substituted naphthyridine and pyridopyrazine derivatives and their use in treating hyperproliferative skin diseases |
US5438062A (en) * | 1986-10-31 | 1995-08-01 | Schering Corporation | Benzo(5,6)cycloheptapyridines, compositions and methods of use |
US4826853A (en) | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
US5089496A (en) * | 1986-10-31 | 1992-02-18 | Schering Corporation | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies |
US5665726A (en) * | 1986-10-31 | 1997-09-09 | Schering Corporation | Benzo[5,6]cycloheptapyridines, compositions and methods of use |
US4843163A (en) * | 1987-12-02 | 1989-06-27 | Smithkline Beckman Corporation | Certain 3-(2-phenethyl)-1-carbamoyloxypyridinium halide intermediates |
JP2766266B2 (ja) * | 1988-06-20 | 1998-06-18 | 協和醗酵工業株式会社 | ピリジン誘導体およびその中間体 |
US4863931A (en) * | 1988-09-15 | 1989-09-05 | Schering Corporation | Antihistaminic fluoro substituted benzocycloheptapyridines |
US4996321A (en) * | 1990-02-26 | 1991-02-26 | Merck & Co., Inc. | Dibenzo[a,d]cycloheptenylidene compounds |
NZ238629A (en) * | 1990-06-22 | 1993-09-27 | Schering Corp | Bis-benzo- or benzopyrido-cyclohepta (where z is c, o, s or n) piperidine, piperidylidene or piperazine compounds, medicaments and methods of preparation |
JPH05506249A (ja) * | 1990-10-10 | 1993-09-16 | シェリング・コーポレーション | ビスーベンゾシクロヘプタピペリジリデン、ピペリジンおよびピペラジン化合物、組成物および使用法 |
WO1992020681A1 (en) * | 1991-05-23 | 1992-11-26 | Schering Corporation | Novel benzopyrido piperidylidene compounds, compositions, methods of manufacture and methods of use |
WO1993002081A1 (en) * | 1991-07-23 | 1993-02-04 | Schering Corporation | Novel benzopyrido piperylidene compounds, compositions, methods of manufacture and methods of use |
ES2040177B1 (es) * | 1992-03-06 | 1994-05-16 | S A Tamarang | Procedimiento para la sintesis de la 8-cloro-6, 11-dihidro-11, (1-etoxicarbonil-4-piperidiliden) -5h-benzo (5,6) ciclohepta-(1,2-b) piridina. |
ES2089815T3 (es) * | 1992-03-27 | 1996-10-01 | Schering Corp | Derivados de bis-aril-carbinol sin enlaces de puente, composiciones y metodos de uso. |
ATE153336T1 (de) * | 1992-03-27 | 1997-06-15 | Schering Corp | Verbrückte bis-aryl-carbinol-derivate, zusammensetzungen und ihre verwendung |
AU4244593A (en) * | 1992-05-19 | 1993-12-13 | Schering Corporation | Pentacyclic antihistamines |
US5464840A (en) * | 1993-12-06 | 1995-11-07 | Schering Corporation | Tricyclic derivatives, compositions and methods of use |
US7211582B1 (en) * | 1994-12-30 | 2007-05-01 | Sepracor Inc. | Methods for treating urticaria using descarboethoxyloratadine |
US5801175A (en) | 1995-04-07 | 1998-09-01 | Schering Corporation | Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
EP0913392B1 (en) * | 1996-04-25 | 2003-07-02 | Nissan Chemical Industries, Limited | Ethylene derivatives and pest controlling agents |
US6509346B2 (en) * | 1998-01-21 | 2003-01-21 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
EP1098882B1 (en) * | 1998-07-24 | 2004-08-25 | Russinsky Limited | A process for preparing benzocycloheptapyridin-11-ones |
US6267986B1 (en) | 1999-09-24 | 2001-07-31 | Ranbaxy Laboratories Limited | Process for the preparation of a controlled drug delivery system containing pseudoephedrine and a long acting antihistamine |
US7541365B2 (en) * | 2001-11-21 | 2009-06-02 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
WO2003084931A1 (en) * | 2002-04-02 | 2003-10-16 | Merck & Co., Inc. | 5h-benzo[4,5]cyclohepta[1,2-b]pyridine nmda/nr2b antagonists |
PT1545548E (pt) * | 2002-08-30 | 2010-09-02 | Nycomed Gmbh | Utilização da combinação de ciclesonida e anti-histamínicos para o tratamento de rinite alérgica |
TWI291467B (en) * | 2002-11-13 | 2007-12-21 | Millennium Pharm Inc | CCR1 antagonists and methods of use therefor |
ES2232332T3 (es) * | 2003-03-12 | 2007-08-16 | Teva Pharmaceutical Industries Ltd | Composiciones farmaceuticas estables de desloratadina. |
NL1026634C2 (nl) * | 2004-07-12 | 2006-01-16 | Willem Jacob Van Der Burg | Psychofarmaceutisch preparaat en werkzame stof daarin. |
US7550478B2 (en) | 2005-06-23 | 2009-06-23 | Merck & Co. Inc. | Tyrosine kinase inhibitors |
US20070036859A1 (en) * | 2005-08-11 | 2007-02-15 | Perry Ronald L | Sustained release antihistamine and decongestant composition |
CA2624656A1 (en) * | 2005-10-21 | 2007-05-03 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
NZ573174A (en) | 2006-06-01 | 2012-01-12 | Msd Consumer Care Inc | Sustained release pharmaceutical dosage form containing phenylephrine |
BRPI0712532A2 (pt) | 2006-06-01 | 2013-04-02 | Schering Plough Healthcare Prod Inc | formulaÇÕes e composiÇÕes farmacÊuticas de fenilefrina para absorÇço colânica |
TW200813021A (en) * | 2006-07-10 | 2008-03-16 | Merck & Co Inc | Tyrosine kinase inhibitors |
US20090082385A1 (en) * | 2007-09-26 | 2009-03-26 | Protia, Llc | Deuterium-enriched desloratidine |
CN101951886A (zh) * | 2007-12-21 | 2011-01-19 | 先灵-普劳健康护理产品公司 | 增强羟甲唑啉的光稳定性 |
CN102993172B (zh) * | 2012-12-19 | 2014-04-02 | 天津大学 | 具有抗组胺活性的三环类化合物、制备方法及用途 |
GB202103803D0 (en) | 2021-03-18 | 2021-05-05 | Queens Univ Of Belfast | Anti-viral therapy |
CN112898268A (zh) * | 2021-04-07 | 2021-06-04 | 深圳振强生物技术有限公司 | 一种地氯雷他定杂质的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
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GB858186A (en) * | 1958-04-03 | 1961-01-11 | Hoffmann La Roche | Novel dibenzoheptaenes and salts thereof and a process for the manufacture of same |
GB858187A (en) * | 1958-04-03 | 1961-01-11 | Hoffmann La Roche | Novel dibenzocycloheptaenes and salts thereof and a process for the manufacture of same |
US3014911A (en) * | 1958-09-29 | 1961-12-26 | Merck & Co Inc | Derivatives of dibenzo[a, e]cycloheptatriene |
US3073847A (en) * | 1959-02-12 | 1963-01-15 | Hoffmann La Roche | 9-(3-amino-1-propynyl) derivatives of 9-xanthenols and 9-thioxanthenols and a process for their preparation |
DE1160442B (de) * | 1959-03-18 | 1964-01-02 | Degussa | Verfahren zur Herstellung von 3-Trifluormethylphenthiazinen |
US3086972A (en) * | 1960-03-24 | 1963-04-23 | Sandoz Ag | Aza-thiaxanthene derivatives |
US3127409A (en) * | 1962-08-08 | 1964-03-31 | Olin Mathieson | Novel dihydropyridobenzoxazepines and dihydropyridobenzthiazepines |
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0
- NL NL132137D patent/NL132137C/xx active
-
1963
- 1963-12-13 US US330244A patent/US3366635A/en not_active Expired - Lifetime
- 1963-12-13 US US330263A patent/US3326924A/en not_active Expired - Lifetime
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1964
- 1964-04-20 CH CH509564A patent/CH535769A/de not_active IP Right Cessation
- 1964-04-20 IL IL21208A patent/IL21208A/xx unknown
- 1964-04-20 CH CH584573A patent/CH544091A/de not_active IP Right Cessation
- 1964-04-21 GB GB16484/64A patent/GB1065191A/en not_active Expired
- 1964-04-22 BR BR158580/64A patent/BR6458580D0/pt unknown
- 1964-04-23 NO NO152953A patent/NO120935B/no unknown
- 1964-04-23 FI FI640863A patent/FI52220C/fi active
- 1964-04-23 FR FR972072A patent/FR4013M/fr not_active Expired
- 1964-04-23 SE SE6912617*3A patent/SE379765B/xx unknown
- 1964-04-23 DK DK205164AA patent/DK125421B/da unknown
- 1964-04-23 DE DE19641795744 patent/DE1795744A1/de active Pending
- 1964-04-23 NL NL6404490A patent/NL6404490A/xx unknown
- 1964-04-23 IT IT08873/64A patent/IT1149233B/it active
- 1964-04-23 DE DE1964SC041153 patent/DE1695853B2/de active Granted
- 1964-04-24 JP JP39022868A patent/JPS4840356B1/ja active Pending
- 1964-04-24 BE BE647043D patent/BE647043A/xx unknown
-
1966
- 1966-08-17 NO NO66164333A patent/NO120938B/no unknown
- 1966-08-17 NO NO66164332A patent/NO121949B/no unknown
- 1966-09-19 US US580169A patent/US3357986A/en not_active Expired - Lifetime
-
1968
- 1968-06-25 SE SE08609/68A patent/SE338317B/xx unknown
- 1968-06-25 SE SE08610/68A patent/SE349030B/xx unknown
- 1968-06-25 SE SE08607/68A patent/SE347745B/xx unknown
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1969
- 1969-09-09 DK DK482469AA patent/DK125133B/da unknown
-
1970
- 1970-06-26 CY CY54370A patent/CY543A/xx unknown
- 1970-12-31 MY MY1970130A patent/MY7000130A/xx unknown
-
1972
- 1972-02-28 IT IT21129/72A patent/IT1123902B/it active
-
1973
- 1973-05-25 JP JP48058500A patent/JPS5030078B1/ja active Pending
- 1973-05-25 JP JP7358499A patent/JPS5030077B1/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DK125133B (da) | 1973-01-02 |
FI52220C (fi) | 1977-07-11 |
BE647043A (cs) | 1964-10-26 |
DE1795745A1 (de) | 1974-08-29 |
SE338317B (cs) | 1971-09-06 |
DE1795745B2 (de) | 1976-04-08 |
SE347745B (cs) | 1972-08-14 |
FR4013M (cs) | 1966-03-21 |
US3366635A (en) | 1968-01-30 |
DE1795744A1 (de) | 1974-11-21 |
IL21208A (en) | 1968-10-24 |
NO121949B (cs) | 1971-05-03 |
JPS5030077B1 (cs) | 1975-09-29 |
DE1695853B2 (de) | 1976-06-16 |
DK125421B (da) | 1973-02-19 |
FI52220B (cs) | 1977-03-31 |
NO120938B (cs) | 1970-12-28 |
CY543A (en) | 1970-06-26 |
CH535769A (de) | 1973-04-15 |
US3357986A (en) | 1967-12-12 |
IT1123902B (it) | 1986-04-30 |
SE349030B (cs) | 1972-09-18 |
NO120935B (cs) | 1970-12-28 |
JPS4840356B1 (cs) | 1973-11-30 |
IT1149233B (it) | 1986-12-03 |
CH544091A (de) | 1973-12-28 |
US3326924A (en) | 1967-06-20 |
SE379765B (cs) | 1975-10-20 |
DE1695853A1 (de) | 1972-03-02 |
JPS5030078B1 (cs) | 1975-09-29 |
BR6458580D0 (pt) | 1973-09-11 |
GB1065191A (en) | 1967-04-12 |
MY7000130A (en) | 1970-12-31 |
NL132137C (cs) |