NL194271C - Werkwijze voor de bereiding van de verbinding L-5-(2-acetoxy-propionylamino)-2,4,6-trijood-isoftaalzuur-bis-(1,3- -dihydropropylamide). - Google Patents

Werkwijze voor de bereiding van de verbinding L-5-(2-acetoxy-propionylamino)-2,4,6-trijood-isoftaalzuur-bis-(1,3- -dihydropropylamide). Download PDF

Info

Publication number
NL194271C
NL194271C NL9301822A NL9301822A NL194271C NL 194271 C NL194271 C NL 194271C NL 9301822 A NL9301822 A NL 9301822A NL 9301822 A NL9301822 A NL 9301822A NL 194271 C NL194271 C NL 194271C
Authority
NL
Netherlands
Prior art keywords
acetoxy
propionylamino
reaction
under stirring
kept under
Prior art date
Application number
NL9301822A
Other languages
English (en)
Dutch (nl)
Other versions
NL194271B (nl
NL9301822A (nl
Inventor
Marco Villa
Antonio Nardi
Fabio Benedetti
Original Assignee
Bracco Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Int Bv filed Critical Bracco Int Bv
Publication of NL9301822A publication Critical patent/NL9301822A/nl
Publication of NL194271B publication Critical patent/NL194271B/xx
Application granted granted Critical
Publication of NL194271C publication Critical patent/NL194271C/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NL9301822A 1992-10-27 1993-10-20 Werkwijze voor de bereiding van de verbinding L-5-(2-acetoxy-propionylamino)-2,4,6-trijood-isoftaalzuur-bis-(1,3- -dihydropropylamide). NL194271C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI922451 1992-10-27
ITMI922451A IT1256163B (it) 1992-10-27 1992-10-27 Processo per la preparazione di un intermedio della sintesi organica

Publications (3)

Publication Number Publication Date
NL9301822A NL9301822A (nl) 1994-05-16
NL194271B NL194271B (nl) 2001-07-02
NL194271C true NL194271C (nl) 2001-11-05

Family

ID=11364170

Family Applications (1)

Application Number Title Priority Date Filing Date
NL9301822A NL194271C (nl) 1992-10-27 1993-10-20 Werkwijze voor de bereiding van de verbinding L-5-(2-acetoxy-propionylamino)-2,4,6-trijood-isoftaalzuur-bis-(1,3- -dihydropropylamide).

Country Status (7)

Country Link
CH (1) CH688147A5 (de)
DE (1) DE4336154A1 (de)
ES (1) ES2073370B1 (de)
FR (1) FR2697249B1 (de)
GB (1) GB2272218B (de)
IT (1) IT1256163B (de)
NL (1) NL194271C (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283319B1 (it) * 1996-03-29 1998-04-16 Zambon Spa Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati
US6262303B1 (en) 1998-05-08 2001-07-17 Dibra S.P.A. Process for the preparation of S-N,N′-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)-amino]-2,4,6-triiodo-1,3-benzenedicarboxamide
IT1299202B1 (it) * 1998-05-08 2000-02-29 Dibra Spa Processo per la preparazione della s-n,n'-bis (2-idrossi-1- (idrossimetil)etil) -5-((2-idrossi-1-ossopropil)ammino)-2,4,6-triiodo
IT1302200B1 (it) * 1998-09-11 2000-07-31 Dibra Spa PROCESSO PER LA PREPARAZIONE DELLA S-N,N'-BIS°2-IDROSSI-1-(IDROSSIMETIL)ETILé-5-°(2-IDROSSI-1-
US6803485B2 (en) 1999-02-26 2004-10-12 Bracco Imaging S.P.A. Process for the preparation of iopamidol

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH608189A5 (de) * 1974-12-13 1978-12-29 Savac Ag
FR2656865B1 (fr) * 1990-01-05 1993-03-26 Guerbet Sa Compose non ionique iode, son procede de preparation et produit de contraste le contenant.
ES2017277A6 (es) * 1989-09-20 1991-01-16 Juste Sa Un procedimiento para la preparacion de nuevos agentes iodados no ionicos de contraste.

Also Published As

Publication number Publication date
GB2272218B (en) 1995-11-22
GB9320888D0 (en) 1993-12-01
CH688147A5 (it) 1997-05-30
IT1256163B (it) 1995-11-29
FR2697249A1 (fr) 1994-04-29
ITMI922451A0 (it) 1992-10-27
FR2697249B1 (fr) 1995-04-14
NL194271B (nl) 2001-07-02
NL9301822A (nl) 1994-05-16
GB2272218A (en) 1994-05-11
ES2073370B1 (es) 1996-02-16
ES2073370A1 (es) 1995-08-01
DE4336154A1 (de) 1994-04-28
ITMI922451A1 (it) 1994-04-27

Similar Documents

Publication Publication Date Title
US6974882B2 (en) Preparation of iodixanol
JPS6328438B2 (de)
NL194272C (nl) Werkwijze voor de kristallisatie van iopamidol.
NL194271C (nl) Werkwijze voor de bereiding van de verbinding L-5-(2-acetoxy-propionylamino)-2,4,6-trijood-isoftaalzuur-bis-(1,3- -dihydropropylamide).
NL194332C (nl) Werkwijze ter bereiding van L-5-(2-hydroxypropionylamino)-2,4,6- trijoodisoftaalzuur-bis-(1,3-dihydroxypropylamide).
NL194993C (nl) Werkwijze voor de bereiding van L-5-(2-acetoxy-propionylamino)-2,4,6-trijodo-isoftaalzuurdichloride.
BG63663B1 (bg) Метод за получаване на йохексол
JP4450987B2 (ja) アルコキシフラノンアミン誘導体の製造方法、この方法で得られた化合物及びこれらの化合物の用途
US5817861A (en) Process for the preparation of an intermediate useful in the synthesis of iodinated contrast media
US4540817A (en) Process for the preparation of 5-amino-2,4-dimethylacetanilide
JPH08333319A (ja) イオパミドールの精製及び晶出方法
JP3291991B2 (ja) O,s−ジメチル n−アセチルホスホルアミドチオエートの精製法
US4914195A (en) Process for preparing N-acetylneuraminic acid derivatives
EP0127128A1 (de) Verfahren zur Umwandlung von 1,2-Diphenyl-1-[4-(2-dimethylamino-ethoxy)-phenyl]-1-buten-E-Isomeren zu Tamoxifen-Hydrochlorid
JP4397990B2 (ja) 3−アルキルフラバノノール誘導体の精製法
NL9001459A (nl) Nieuwe stereoselectieve hydrogeneringswerkwijze.
KR20000070926A (ko) 선형 또는 분지형 (c5-c6) 알콜 또는 그의 혼합물로부터 (s)-n,n'-비스[2-히드록시-1-(히드록시메틸)에틸]-5-[(2-히드록시-1-옥소프로필)아미노]-2,4,6-트리요오도-1,3-벤젠디카르복스아미드의 결정화 방법
US4676933A (en) Method for purification of amido acids
CA2710577C (en) Crystallization of iodixanol using milling
JP2003095991A (ja) 光学活性3,3,3−トリフルオロ−2−ヒドロキシ−2−メチルプロピオン酸の製造法
SK4302002A3 (en) Method for the preparation of (E)-N-(6,6-dimethylhept-2-en-4- ynyl)-N-methyl-1-naphthalenemethanamine from a geometric isomers mixture
JPH0368571A (ja) N―置換2、4、6―トリイミノトリアジン誘導体の製造方法
PL114673B2 (en) Process for purification of alpha-pyroglutamic acid from impurities,especially from alpha-glutamic acid and derivatives of alpha-pyroglutamic acid
JPH0794427B2 (ja) N,n―ジアルキルアミノチオアセトアミドの製造法
JPH10147560A (ja) N−2−ブロモエチル−アミノ安息香酸誘導体の製造方法

Legal Events

Date Code Title Description
BB A search report has been drawn up
BC A request for examination has been filed
CNR Transfer of rights (patent application after its laying open for public inspection)

Free format text: BRACCO INTERNATIONAL B.V.

SNR Assignments of patents or rights arising from examined patent applications

Owner name: BRACCO IMAGING S.P.A.

V4 Discontinued because of reaching the maximum lifetime of a patent

Effective date: 20131020