NL194203C - 1,4-dihydropyridineverbindingen en farmaceutisch preparaat dat ÚÚn of meer van deze bevat. - Google Patents
1,4-dihydropyridineverbindingen en farmaceutisch preparaat dat ÚÚn of meer van deze bevat. Download PDFInfo
- Publication number
- NL194203C NL194203C NL8204014A NL8204014A NL194203C NL 194203 C NL194203 C NL 194203C NL 8204014 A NL8204014 A NL 8204014A NL 8204014 A NL8204014 A NL 8204014A NL 194203 C NL194203 C NL 194203C
- Authority
- NL
- Netherlands
- Prior art keywords
- dihydropyridine
- dimethyl
- compounds
- dicarboxylate
- nitrophenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16696381A JPS5867668A (ja) | 1981-10-19 | 1981-10-19 | １，４−ジヒドロピリジン誘導体 |
| JP16696381 | 1981-10-19 | ||
| JP259782A JPS58121288A (ja) | 1982-01-11 | 1982-01-11 | １，４−ジヒドロピリジン誘導体 |
| JP259782 | 1982-01-11 | ||
| JP2839182A JPS58146565A (ja) | 1982-02-24 | 1982-02-24 | １，４−ジヒドロピリジン誘導体 |
| JP2839182 | 1982-02-24 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NL8204014A NL8204014A (nl) | 1983-05-16 |
| NL194203B NL194203B (nl) | 2001-05-01 |
| NL194203C true NL194203C (nl) | 2001-09-04 |
Family
ID=27275435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL8204014A NL194203C (nl) | 1981-10-19 | 1982-10-18 | 1,4-dihydropyridineverbindingen en farmaceutisch preparaat dat ÚÚn of meer van deze bevat. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4446325A (it) |
| KR (1) | KR880002704B1 (it) |
| AU (1) | AU555036B2 (it) |
| CA (1) | CA1177079A (it) |
| CH (1) | CH650498A5 (it) |
| DE (1) | DE3238705A1 (it) |
| ES (2) | ES8406439A1 (it) |
| FR (1) | FR2514761B1 (it) |
| GB (1) | GB2111978B (it) |
| IT (1) | IT1189393B (it) |
| NL (1) | NL194203C (it) |
| SE (1) | SE442864B (it) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE57810B1 (en) * | 1984-03-27 | 1993-04-21 | Delagrange Lab | 1,4-dihydropyridine derivatives,their preparation and their use |
| FR2577552B1 (fr) * | 1985-02-20 | 1987-09-04 | Sori Soc Rech Ind | Esters heterocycliques dissymetriques d'acides 1,4-dihydropyridine-3,5-dicarboxyliques, procede de preparation et utilisation en therapeutique |
| US4833150A (en) * | 1985-03-14 | 1989-05-23 | Nelson Research & Development Co. | 1,4-dihydropyridines |
| DE3514865A1 (de) * | 1985-04-25 | 1986-11-06 | Bayer Ag, 5090 Leverkusen | 1,4-dihydropyridin-derivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
| US4849436A (en) * | 1986-03-11 | 1989-07-18 | Nelson Research & Development Co. | 1,4-dihydropyridines |
| ATE68704T1 (de) * | 1986-12-18 | 1991-11-15 | Bauer Kurt Heinz | Gegenueber lichteinfluss stabilisiertes nifedipin- konzentrat und verfahren zu seiner herstellung. |
| CN100450483C (zh) * | 2000-04-11 | 2009-01-14 | 三共株式会社 | 含有钙阻滞剂的稳定药物组合物 |
| CN1681495B (zh) | 2002-08-19 | 2010-05-12 | 辉瑞产品公司 | 用于治疗过度增生性疾病的组合物 |
| BRPI0513866A (pt) * | 2004-07-26 | 2008-05-20 | Cotherix Inc | composição, micropartìculas, método para o tratamento da hipertensão pulmonar, e dispositivo de inalação |
| US7893050B2 (en) * | 2005-10-26 | 2011-02-22 | Asahi Kasei Pharma Corporation | Fasudil in combination therapies for the treatment of pulmonary arterial hypertension |
| EP2351569B1 (en) | 2005-10-26 | 2012-08-22 | Asahi Kasei Pharma Corporation | Fasudil in combination therapies for the treatment of pulmonary arterial hypertension |
| TW200736245A (en) * | 2005-11-29 | 2007-10-01 | Sankyo Co | Acid addition salts of optically active dihydropyridine derivatives |
| TW200806648A (en) * | 2005-11-29 | 2008-02-01 | Sankyo Co | Acid addition salts of dihydropyridine derivatives |
| US8883844B2 (en) | 2010-09-24 | 2014-11-11 | Nitrogenix Inc. | Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions |
| BR112014004370A2 (pt) | 2011-08-26 | 2017-03-21 | Wockhardt Ltd | métodos para tratar distúrbios cardiovasculares |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1670827C3 (de) * | 1967-03-20 | 1974-10-24 | Bayer Ag, 5090 Leverkusen | 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin |
| DE1670824C3 (de) * | 1967-03-20 | 1978-08-03 | Bayer Ag, 5090 Leverkusen | 1,4-Dihydropyridin-33-dicarbonsäurealkylester |
| DE2228363A1 (de) * | 1972-06-10 | 1974-01-03 | Bayer Ag | 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DE2747513A1 (de) * | 1977-10-22 | 1979-05-03 | Bayer Ag | Dihydropyridine mit schwefelhaltigen estergruppierungen |
| DE2847236A1 (de) * | 1978-10-31 | 1980-05-14 | Bayer Ag | Neue dihydropyridine mit substituierten estergruppierungen, mehrer verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DE2935451A1 (de) * | 1979-09-01 | 1981-03-19 | Bayer Ag, 5090 Leverkusen | Optisch aktive 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arneimittel |
| NZ201395A (en) * | 1981-07-30 | 1987-02-20 | Bayer Ag | Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines |
-
1982
- 1982-10-11 GB GB08229020A patent/GB2111978B/en not_active Expired
- 1982-10-13 AU AU89317/82A patent/AU555036B2/en not_active Expired
- 1982-10-18 IT IT49295/82A patent/IT1189393B/it active
- 1982-10-18 CH CH6058/82A patent/CH650498A5/de not_active IP Right Cessation
- 1982-10-18 NL NL8204014A patent/NL194203C/nl not_active IP Right Cessation
- 1982-10-18 SE SE8205905A patent/SE442864B/sv not_active IP Right Cessation
- 1982-10-19 KR KR8204705A patent/KR880002704B1/ko active
- 1982-10-19 DE DE19823238705 patent/DE3238705A1/de active Granted
- 1982-10-19 ES ES517022A patent/ES8406439A1/es not_active Expired
- 1982-10-19 CA CA000413717A patent/CA1177079A/en not_active Expired
- 1982-10-19 US US06/435,183 patent/US4446325A/en not_active Expired - Lifetime
- 1982-10-19 FR FR8217497A patent/FR2514761B1/fr not_active Expired
-
1983
- 1983-11-30 ES ES527980A patent/ES527980A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| GB2111978A (en) | 1983-07-13 |
| US4446325A (en) | 1984-05-01 |
| GB2111978B (en) | 1985-05-01 |
| KR840001954A (ko) | 1984-06-07 |
| IT1189393B (it) | 1988-02-04 |
| DE3238705A1 (de) | 1983-07-14 |
| NL8204014A (nl) | 1983-05-16 |
| ES8504127A1 (es) | 1985-04-16 |
| AU555036B2 (en) | 1986-09-11 |
| FR2514761B1 (fr) | 1985-09-06 |
| AU8931782A (en) | 1983-04-28 |
| IT8249295A0 (it) | 1982-10-18 |
| ES517022A0 (es) | 1984-08-16 |
| SE442864B (sv) | 1986-02-03 |
| ES8406439A1 (es) | 1984-08-16 |
| CH650498A5 (de) | 1985-07-31 |
| SE8205905L (sv) | 1983-04-20 |
| KR880002704B1 (ko) | 1988-12-26 |
| CA1177079A (en) | 1984-10-30 |
| NL194203B (nl) | 2001-05-01 |
| DE3238705C2 (it) | 1989-11-09 |
| FR2514761A1 (fr) | 1983-04-22 |
| SE8205905D0 (sv) | 1982-10-18 |
| ES527980A0 (es) | 1985-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A85 | Still pending on 85-01-01 | ||
| BA | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| V4 | Discontinued because of reaching the maximum lifetime of a patent |
Free format text: 20021018 |