NL193216C - Diethylammonium-2-(2,6-dichlooranilino)-fenylacetaat en topicaal toepasbaar preparaat dat het bevat. - Google Patents

Diethylammonium-2-(2,6-dichlooranilino)-fenylacetaat en topicaal toepasbaar preparaat dat het bevat. Download PDF

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Publication number
NL193216C
NL193216C NL8100917A NL8100917A NL193216C NL 193216 C NL193216 C NL 193216C NL 8100917 A NL8100917 A NL 8100917A NL 8100917 A NL8100917 A NL 8100917A NL 193216 C NL193216 C NL 193216C
Authority
NL
Netherlands
Prior art keywords
active substance
water
dichloroanilino
diethylammonium
phenyl acetate
Prior art date
Application number
NL8100917A
Other languages
English (en)
Dutch (nl)
Other versions
NL193216B (nl
NL8100917A (nl
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10519933&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL193216(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NL8100917A publication Critical patent/NL8100917A/xx
Publication of NL193216B publication Critical patent/NL193216B/xx
Application granted granted Critical
Publication of NL193216C publication Critical patent/NL193216C/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
NL8100917A 1981-02-24 1981-02-25 Diethylammonium-2-(2,6-dichlooranilino)-fenylacetaat en topicaal toepasbaar preparaat dat het bevat. NL193216C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8105822A GB2093693B (en) 1981-02-24 1981-02-24 Pharmaceutical preparations for topical application which contain salts of alkanecarboxylic acids novel carboxylic acid salts and the production thereof
GB8105822 1981-02-24

Publications (3)

Publication Number Publication Date
NL8100917A NL8100917A (nl) 1982-09-16
NL193216B NL193216B (nl) 1998-11-02
NL193216C true NL193216C (nl) 1999-03-03

Family

ID=10519933

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8100917A NL193216C (nl) 1981-02-24 1981-02-25 Diethylammonium-2-(2,6-dichlooranilino)-fenylacetaat en topicaal toepasbaar preparaat dat het bevat.

Country Status (12)

Country Link
US (4) US4407824A (fr)
AT (1) AT370721B (fr)
CA (1) CA1180008A (fr)
CY (2) CY1443A (fr)
FR (2) FR2500751A1 (fr)
GB (2) GB2093693B (fr)
HK (1) HK83888A (fr)
KE (1) KE3820A (fr)
LU (1) LU83945A1 (fr)
NL (1) NL193216C (fr)
SE (2) SE448088B (fr)
SG (1) SG33388G (fr)

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FR2526427A1 (fr) * 1982-05-04 1983-11-10 Bouchara Emile Nouveau sel d'indometacine, son procede de preparation et les compositions pharmaceutiques en renfermant
US4437053A (en) * 1982-05-10 1984-03-13 Diasonics (Nmr) Inc. Gradient power supply
CH655656B (fr) * 1982-10-07 1986-05-15
ES516786A0 (es) * 1982-10-08 1984-09-01 Espinos & Bofill Lab Sa Procedimiento para la obtencion de un nuevo derivado del sulpiride.
JPS59137408A (ja) * 1983-01-27 1984-08-07 Taisho Pharmaceut Co Ltd 軟膏
JPS59139315A (ja) * 1983-01-31 1984-08-10 Taisho Pharmaceut Co Ltd クリ−ム剤
CH643138A5 (de) * 1983-08-29 1984-05-30 Mepha Ag Indomethacin enthaltende, gelartige salbe.
DE3381733D1 (de) * 1983-12-08 1990-08-16 Toko Yakuhin Kogyo Kk Gelpraeparate zur externen applikation.
US4670254A (en) * 1983-12-09 1987-06-02 Toko Yakuhin Industry Co., Ltd. Gel preparations for topical application of diclofenac sodium
DE3423589A1 (de) * 1984-06-27 1986-01-09 Wella Ag, 6100 Darmstadt Oxidationshaarfaerbemittel auf basis einer niedrigviskosen traegermasse
IT1178411B (it) * 1984-09-06 1987-09-09 Sigma Tau Ind Farmaceuti Sale di d,l-lisina dell'acido 1-(4-clorobenzoil)-5-metossi-2-metil-1h-indol-3 acetico, procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono
CA1265288A (fr) * 1984-11-22 1990-01-30 E. I. Du Pont De Nemours And Company Compositions de fluoroelastomere etuvable
US4980084A (en) * 1985-09-11 1990-12-25 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Water rinsable petroleum jelly compositions
US4690774A (en) * 1985-09-11 1987-09-01 Chesebrough Pond's Inc. Novel translucent water in oil emulsions
US4832858A (en) * 1987-02-19 1989-05-23 Chesebrough-Pond's Inc. Water dispersible petroleum jelly compositions
US4960892A (en) * 1988-06-10 1990-10-02 American Home Products Corporation Naphthalenepropionic acid derivatives as anti-inflammatory/anti-allergic agents
TW225536B (fr) * 1990-08-23 1994-06-21 Ciba Geigy Ag
US5444076A (en) * 1990-11-26 1995-08-22 Roemmers S.A.I.C.F. Pharmaceutical preparation for topical application
CA2112751A1 (fr) * 1991-07-03 1993-01-21 Charles J. Ii Betlach Composition et methode pour l'injection transdermique de diclofenac
US6117907A (en) * 1993-04-14 2000-09-12 Sher; Neal A. Topical treatment of ocular pain after corneal surgery
JP3526887B2 (ja) * 1993-04-23 2004-05-17 帝國製薬株式会社 消炎鎮痛外用貼付剤
FI100692B (fi) * 1994-05-24 1998-02-13 Leiras Oy Menetelmä farmaseuttisten koostumusten valmistamiseksi, jolloin koostu mukset pohjautuvat mikroemulsiogeeleihin sekä uusia mikroemulsioihin p ohjautuvia geelejä
WO1996000716A1 (fr) * 1994-06-29 1996-01-11 Ciba-Geigy Ag Nouveaux sels d'acide 2-[(2,6-dichlorophenyl) amine] phenylacetoxyacetique a cations basiques organiques
US20030060657A1 (en) * 1998-04-28 2003-03-27 Russinsky Limited Process for the preparation of Aceclofenac
TWI290464B (en) 2000-09-01 2007-12-01 Novartis Consumer Health Sa Treatment of burns
DE10114561A1 (de) * 2001-03-24 2002-09-26 Wella Ag Verwendung von Mitteln enthaltend Kreatin, Kreatin und/oder deren Derivaten zur Verstärkung und Strukturverbesserung von keratinischen Fasern
ITMI20020986A1 (it) * 2002-05-10 2003-11-10 Acraf Composizione a base di diclofenac per il trattamento topico di affezioni del cavo orofaringeo
PE20040844A1 (es) 2002-11-26 2004-12-30 Novartis Ag Acidos fenilaceticos y derivados como inhibidores de la cox-2
ITMI20030269A1 (it) * 2003-02-14 2004-08-15 Advance Holdings Ltd Sale di cetilpiridino di un agente antiinfiammatorio
FR2854802B1 (fr) * 2003-05-12 2005-06-24 Galderma Res & Dev Procede de preparation d'une formulation contenant un principe actif microdose
EP2055298A1 (fr) 2007-10-30 2009-05-06 Novartis AG Composition topique
RU2702898C2 (ru) 2014-09-10 2019-10-14 Гск Консьюмер Хелткер С.А. Композиции диклофенака натрия для местного применения
CN116143647A (zh) * 2023-03-03 2023-05-23 长沙晶易医药科技股份有限公司 双氯芬酸二乙胺的新晶型及其制备方法

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GB971700A (en) * 1961-02-02 1964-09-30 Boots Pure Drug Co Ltd Anti-Inflammatory Agents
AT290523B (de) * 1962-01-05 1971-06-11 Merck & Co Inc Verfahren zur Herstellung neuer α-(3-Indolyl)-carbonsäuren
US3558690A (en) * 1965-04-08 1971-01-26 Gelgy Chemical Corp Substituted derivatives of 2-anilinophenylacetic acids and a process of preparation
CH470349A (de) * 1966-10-07 1969-03-31 Geigy Ag J R Verfahren zur Herstellung von neuen substituierten Phenylessigsäuren
CA960689A (en) * 1967-01-13 1975-01-07 Syntex Corporation 2-naphthyl acetic acid derivatives and compositions
US3896157A (en) * 1967-01-13 1975-07-22 Syntex Corp Dihydo 2-naphthylacetic acid derivatives
US4048330A (en) * 1967-01-13 1977-09-13 Syntex Corporation Compositions containing 2-(6'-substituted-2'-naphthyl)acetic acid esters used for treating inflammation, pain or pyrexia
FR1546478A (fr) * 1967-01-27 1968-11-22 Rhone Poulenc Sa Nouveaux dérivés de l'acide benzoyl-3 phénylacétique et leur préparation
US3592902A (en) * 1967-04-13 1971-07-13 Sumitomo Chemical Co Injection
DK125461B (da) * 1967-12-20 1973-02-26 Ciba Geigy Ag Fremgangsmåde til fremstilling af substituerede phenyleddikesyrer eller salte deraf.
US3641040A (en) * 1968-03-27 1972-02-08 Ciba Geigy Corp Tertiary amino phenyl acetic acids
US3637767A (en) * 1968-07-30 1972-01-25 Syntex Corp 2-(6'-methoxynaphth-2'-yl)propylene oxide and 5'-halo derivatives
BR6915470D0 (pt) * 1969-03-24 1973-03-13 Syntex Corp Processo para preparar derivados de acido 2-(6'substituido 2'naftil)propionico e de seus sais
US3752826A (en) * 1970-01-26 1973-08-14 Mcneilab Inc Aroyl substituted pyrroles
US3647858A (en) * 1970-05-01 1972-03-07 Merck & Co Inc Process for preparing 1-benzylidene-3-indenyl acetic acids
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ES423834A1 (es) * 1974-03-02 1976-06-01 Roger Lab Procedimiento de obtencion de una nueva sal de piperacina del acido (1 - p - clorobenzoil - 2 - metil - 5 - metoxi - 3- indolil) acetico.
US4031243A (en) * 1975-07-03 1977-06-21 Juste, S.A. Quimico-Farmaceutica 2-(4-Isobutyl phenyl)butyric acid, salts thereof, and pharmaceutical compositions containing the same
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JPS549240A (en) * 1977-06-23 1979-01-24 Asahi Chem Ind Co Ltd New derivative of phenylglycolic acid, its preparation and analgesic and antiinflammatory agent contining it as effective component
GB2023000B (en) * 1978-06-17 1982-10-13 Kowa Co Antinflammatory analgesic gelled ointments
BE871335A (fr) * 1978-10-18 1979-04-18 Bago Sa Labor Derives solubles des acides 2-anilino-aryl-carboxyliques substitues utiles par la voie buccale comme agents anti-inflammatoires.
LU83138A1 (de) * 1981-02-16 1981-09-11 T Eckert Topische pharmazeutische praeparate,enthaltend salze von alkancarbonsaeuren sowie neue carbonsaeuresalze und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
LU83945A1 (de) 1982-12-13
GB2093693B (en) 1985-10-02
FR2500751B1 (fr) 1984-12-28
ATA70981A (de) 1982-09-15
HK83888A (en) 1988-10-21
FR2514348B1 (fr) 1984-12-14
SE448088B (sv) 1987-01-19
NL193216B (nl) 1998-11-02
AT370721B (de) 1983-04-25
US4784808A (en) 1988-11-15
FR2514348A1 (fr) 1983-04-15
SG33388G (en) 1988-09-30
SE8101064L (sv) 1982-08-18
GB2093693A (en) 1982-09-08
US4551475A (en) 1985-11-05
US4619926A (en) 1986-10-28
KE3820A (en) 1988-09-09
SE8203228L (sv) 1982-08-18
NL8100917A (nl) 1982-09-16
US4407824A (en) 1983-10-04
CY1444A (en) 1989-03-10
GB2143528B (en) 1985-10-02
CA1180008A (fr) 1984-12-27
FR2500751A1 (fr) 1982-09-03
GB2143528A (en) 1985-02-13
CY1443A (en) 1989-03-10
GB8418021D0 (en) 1984-08-22

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Legal Events

Date Code Title Description
BT A notification was added to the application dossier and made available to the public
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
CNR Transfer of rights (patent application after its laying open for public inspection)

Free format text: NOVARTIS AG

V4 Discontinued because of reaching the maximum lifetime of a patent

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