NL192385C - 6-alkyl-4-fenyl-1,4-dihydro-3,5-pyridinecarbonzuuresters, werkwijze voor de bereiding daarvan en farmaceutische preparaten die deze esters bevatten. - Google Patents

6-alkyl-4-fenyl-1,4-dihydro-3,5-pyridinecarbonzuuresters, werkwijze voor de bereiding daarvan en farmaceutische preparaten die deze esters bevatten. Download PDF

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Publication number
NL192385C
NL192385C NL8602117A NL8602117A NL192385C NL 192385 C NL192385 C NL 192385C NL 8602117 A NL8602117 A NL 8602117A NL 8602117 A NL8602117 A NL 8602117A NL 192385 C NL192385 C NL 192385C
Authority
NL
Netherlands
Prior art keywords
formula
phenyl
group
methyl
compounds
Prior art date
Application number
NL8602117A
Other languages
English (en)
Dutch (nl)
Other versions
NL192385B (nl
NL8602117A (nl
Original Assignee
Glaxo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT21958/85A external-priority patent/IT1201455B/it
Priority claimed from IT19480/86A external-priority patent/IT1204458B/it
Application filed by Glaxo Spa filed Critical Glaxo Spa
Publication of NL8602117A publication Critical patent/NL8602117A/nl
Publication of NL192385B publication Critical patent/NL192385B/xx
Application granted granted Critical
Publication of NL192385C publication Critical patent/NL192385C/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NL8602117A 1985-08-21 1986-08-20 6-alkyl-4-fenyl-1,4-dihydro-3,5-pyridinecarbonzuuresters, werkwijze voor de bereiding daarvan en farmaceutische preparaten die deze esters bevatten. NL192385C (nl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IT2195885 1985-08-21
IT21958/85A IT1201455B (it) 1985-08-21 1985-08-21 Derivati piridinici sostituiti
IT19480/86A IT1204458B (it) 1986-02-20 1986-02-20 Derivati eterociclici
IT1948086 1986-02-20

Publications (3)

Publication Number Publication Date
NL8602117A NL8602117A (nl) 1987-03-16
NL192385B NL192385B (nl) 1997-03-03
NL192385C true NL192385C (nl) 1997-07-04

Family

ID=26327180

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8602117A NL192385C (nl) 1985-08-21 1986-08-20 6-alkyl-4-fenyl-1,4-dihydro-3,5-pyridinecarbonzuuresters, werkwijze voor de bereiding daarvan en farmaceutische preparaten die deze esters bevatten.

Country Status (18)

Country Link
US (1) US5162345A (de)
JP (1) JPH0696552B2 (de)
AT (1) AT394043B (de)
AU (1) AU588352B2 (de)
BE (1) BE905297A (de)
CA (1) CA1337295C (de)
CH (1) CH669788A5 (de)
CY (1) CY1554A (de)
DE (1) DE3628215C2 (de)
DK (1) DK397686A (de)
ES (1) ES2001104A6 (de)
FR (1) FR2586417B1 (de)
GB (1) GB2181127B (de)
IE (1) IE59632B1 (de)
NL (1) NL192385C (de)
NZ (1) NZ217282A (de)
SE (1) SE465367B (de)
SG (1) SG40890G (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9405833D0 (en) * 1994-03-24 1994-05-11 Pfizer Ltd Separation of the enantiomers of amlodipine
AU761467B2 (en) * 1998-06-09 2003-06-05 Ajinomoto Co., Inc. Novel enzyme-treated protein-containing food, and methods for producing the same
FR2892412B1 (fr) * 2005-10-26 2008-05-16 Galderma Res & Dev Composes biaromatiques modulateurs des ppars

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3455945A (en) * 1967-06-07 1969-07-15 Smithkline Corp 4-(carboxy (and carbo-lower alkoxy)phenyl)-1,4-dihydropyridines
DE2228363A1 (de) * 1972-06-10 1974-01-03 Bayer Ag 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB1409865A (en) * 1973-02-13 1975-10-15 Science Union & Cie Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them
DE2740080A1 (de) * 1977-09-06 1979-03-15 Bayer Ag 2-alkylenaminodihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2753946A1 (de) * 1977-12-03 1979-06-13 Bayer Ag 1-n-aryl-1,4-dihydropyridine und ihre verwendung als arzneimittel
US4307103A (en) * 1978-09-08 1981-12-22 Fujisawa Pharmaceutical Co., Ltd. Dihydropyridine derivative, processes for preparation thereof and pharmaceutical composition comprising the same
CS228917B2 (en) * 1981-03-14 1984-05-14 Pfizer Method of preparing substituted derivatives of 1,4-dihydropyridine
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
AU561213B2 (en) * 1983-06-02 1987-04-30 Teijin Limited 1, 4-dihydropyridine derivative
NZ212895A (en) * 1984-08-22 1988-07-28 Glaxo Spa 1,4-dihydropyridine derivatives and pharmaceutical compositions
IT1204462B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici
DE3607821A1 (de) * 1986-03-08 1987-09-10 Bayer Ag Aminoester-dihydropyridine, verfahren zur herstellung und ihre verwendung
US4814455A (en) * 1986-04-16 1989-03-21 Bristol-Myers Company Dihydro-3,5-dicarboxylates

Also Published As

Publication number Publication date
GB2181127B (en) 1989-08-02
NL192385B (nl) 1997-03-03
NZ217282A (en) 1989-01-27
SG40890G (en) 1990-08-03
SE8603517L (sv) 1987-02-22
FR2586417A1 (fr) 1987-02-27
DE3628215A1 (de) 1987-02-26
NL8602117A (nl) 1987-03-16
SE8603517D0 (sv) 1986-08-20
IE59632B1 (en) 1994-03-09
GB2181127A (en) 1987-04-15
CY1554A (en) 1991-03-22
AU6166886A (en) 1987-02-26
JPS6296467A (ja) 1987-05-02
BE905297A (fr) 1987-02-20
CH669788A5 (de) 1989-04-14
IE862227L (en) 1987-02-21
JPH0696552B2 (ja) 1994-11-30
US5162345A (en) 1992-11-10
DK397686A (da) 1987-02-22
DK397686D0 (da) 1986-08-20
FR2586417B1 (fr) 1991-08-30
ES2001104A6 (es) 1988-04-16
DE3628215C2 (de) 1996-09-19
CA1337295C (en) 1995-10-10
AU588352B2 (en) 1989-09-14
SE465367B (sv) 1991-09-02
ATA223986A (de) 1991-07-15
AT394043B (de) 1992-01-27
GB8620217D0 (en) 1986-10-01

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BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
V1 Lapsed because of non-payment of the annual fee

Effective date: 19980301