NL127995C - - Google Patents
Info
- Publication number
- NL127995C NL127995C NL127995DA NL127995C NL 127995 C NL127995 C NL 127995C NL 127995D A NL127995D A NL 127995DA NL 127995 C NL127995 C NL 127995C
- Authority
- NL
- Netherlands
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33229663A | 1963-12-20 | 1963-12-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
NL127995C true NL127995C (ko) |
Family
ID=23297612
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL127995D NL127995C (ko) | 1963-12-20 | ||
NL6414821A NL6414821A (ko) | 1963-12-20 | 1964-12-18 | |
NL6414820A NL6414820A (ko) | 1963-12-20 | 1964-12-18 |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL6414821A NL6414821A (ko) | 1963-12-20 | 1964-12-18 | |
NL6414820A NL6414820A (ko) | 1963-12-20 | 1964-12-18 |
Country Status (12)
Country | Link |
---|---|
AT (4) | AT249276B (ko) |
BE (2) | BE657406A (ko) |
CH (7) | CH446371A (ko) |
DE (2) | DE1445854A1 (ko) |
DK (4) | DK108496C (ko) |
ES (4) | ES307302A1 (ko) |
FR (2) | FR4346M (ko) |
GB (2) | GB1077711A (ko) |
IL (2) | IL22643A (ko) |
NL (3) | NL6414821A (ko) |
NO (2) | NO119274B (ko) |
SE (2) | SE322779B (ko) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7923454B2 (en) | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
WO2003097608A2 (en) | 2002-05-17 | 2003-11-27 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
US7501433B2 (en) | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
US8835426B2 (en) | 2007-02-26 | 2014-09-16 | Vitae Pharmaceuticals, Inc. | Cyclic urea and carbamate inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
CA2697147A1 (en) | 2007-07-26 | 2009-02-05 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1 |
AR069207A1 (es) | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1 |
WO2009063061A2 (en) | 2007-11-16 | 2009-05-22 | Boehringer Ingelheim International Gmbh | Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
WO2009075835A1 (en) | 2007-12-11 | 2009-06-18 | Vitae Pharmaceutical, Inc | CYCLIC UREA INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE 1 |
TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
JP5490020B2 (ja) | 2008-01-24 | 2014-05-14 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状カルバゼート及びセミカルバジドインヒビター |
WO2009102428A2 (en) | 2008-02-11 | 2009-08-20 | Vitae Pharmaceuticals, Inc. | 1,3-OXAZEPAN-2-ONE AND 1,3-DIAZEPAN-2-ONE INHIBITORS OF 11β -HYDROXYSTEROID DEHYDROGENASE 1 |
CA2711757C (en) * | 2008-02-12 | 2016-07-26 | Boehringer Ingelheim International Gmbh | Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
EP2254872A2 (en) | 2008-02-15 | 2010-12-01 | Vitae Pharmaceuticals, Inc. | Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
EP2300461B1 (en) | 2008-05-01 | 2013-04-17 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
EP2291370B1 (en) | 2008-05-01 | 2013-11-27 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
EP2291373B1 (en) | 2008-05-01 | 2013-09-11 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
CL2009001058A1 (es) | 2008-05-01 | 2010-09-10 | Vitae Pharmaceuticals Inc | Compuestos derivados de oxazinas sustituidas, inhibidores de la 11b-hidroxiesteroide deshidrogenasa de tipo-1; composicion farmaceutica; y uso del compuesto para inhibir la actividad de 11b-hsd1, como en el tratamiento de la diabetes, dislipidemia, hipertension, obesidad, cancer, glaucoma, entre otras. |
WO2009138386A2 (en) | 2008-05-13 | 2009-11-19 | Boehringer Ingelheim International Gmbh | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use |
CN102119160B (zh) | 2008-07-25 | 2014-11-05 | 贝林格尔·英格海姆国际有限公司 | 11β-羟基类固醇脱氢酶1的环状抑制剂 |
JP5777030B2 (ja) | 2008-07-25 | 2015-09-09 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 11β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤 |
TW201022266A (en) | 2008-10-23 | 2010-06-16 | Boehringer Ingelheim Int | Urea derivatives of substituted nortropanes, medicaments containing such compounds and their use |
EP2393807B1 (en) | 2009-02-04 | 2013-08-14 | Boehringer Ingelheim International GmbH | Cyclic inhibitors of 11 -hydroxysteroid dehydrogenase 1 |
UA109255C2 (ru) | 2009-04-30 | 2015-08-10 | Берінгер Інгельхайм Інтернешнл Гмбх | Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1 |
WO2010139673A1 (en) | 2009-06-02 | 2010-12-09 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
WO2011011123A1 (en) | 2009-06-11 | 2011-01-27 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure |
US8883778B2 (en) | 2009-07-01 | 2014-11-11 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1 |
UY33001A (es) | 2009-11-06 | 2011-05-31 | Boehringer Ingelheim Int | Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina |
US8933072B2 (en) | 2010-06-16 | 2015-01-13 | Vitae Pharmaceuticals, Inc. | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use |
EP2585444B1 (en) | 2010-06-25 | 2014-10-22 | Boehringer Ingelheim International GmbH | Azaspirohexanones as inhibitors of 11-beta-hsd1 for the treatment of metabolic disorders |
CN103179960A (zh) | 2010-11-02 | 2013-06-26 | 贝林格尔.英格海姆国际有限公司 | 治疗代谢疾病的药物组合 |
TWI537258B (zh) | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜環芳基羰基衍生物 |
EP2744783A1 (en) | 2011-08-17 | 2014-06-25 | Boehringer Ingelheim International GmbH | Indenopyridine derivatives |
-
0
- NL NL127995D patent/NL127995C/xx active
-
1964
- 1964-11-30 CH CH1538464A patent/CH446371A/de unknown
- 1964-11-30 CH CH1619167A patent/CH449643A/de unknown
- 1964-11-30 CH CH1618967A patent/CH449641A/de unknown
- 1964-11-30 CH CH1619067A patent/CH449642A/de unknown
- 1964-11-30 CH CH1538364A patent/CH448118A/de unknown
- 1964-11-30 CH CH1618767A patent/CH449639A/de unknown
- 1964-11-30 CH CH1618867A patent/CH449640A/de unknown
- 1964-12-18 SE SE1536064A patent/SE322779B/xx unknown
- 1964-12-18 GB GB5149864A patent/GB1077711A/en not_active Expired
- 1964-12-18 AT AT392865A patent/AT249276B/de active
- 1964-12-18 GB GB5150064A patent/GB1092394A/en not_active Expired
- 1964-12-18 AT AT1074364A patent/AT253687B/de active
- 1964-12-18 SE SE1536164A patent/SE305657B/xx unknown
- 1964-12-18 IL IL2264364A patent/IL22643A/xx unknown
- 1964-12-18 DE DE19641445854 patent/DE1445854A1/de active Pending
- 1964-12-18 AT AT1074264A patent/AT261126B/de active
- 1964-12-18 NL NL6414821A patent/NL6414821A/xx unknown
- 1964-12-18 DE DE19641445853 patent/DE1445853A1/de active Pending
- 1964-12-18 AT AT392965A patent/AT249277B/de active
- 1964-12-18 IL IL2264264A patent/IL22642A/xx unknown
- 1964-12-18 NL NL6414820A patent/NL6414820A/xx unknown
- 1964-12-19 NO NO15606364A patent/NO119274B/no unknown
- 1964-12-19 DK DK429765A patent/DK108496C/da active
- 1964-12-19 ES ES0307302A patent/ES307302A1/es not_active Expired
- 1964-12-19 DK DK626764A patent/DK108495C/da active
- 1964-12-19 ES ES0307301A patent/ES307301A1/es not_active Expired
- 1964-12-19 ES ES0307299A patent/ES307299A1/es not_active Expired
- 1964-12-19 DK DK429865A patent/DK108497C/da active
- 1964-12-19 DK DK626864A patent/DK106552C/da active
- 1964-12-19 ES ES0307300A patent/ES307300A1/es not_active Expired
- 1964-12-19 NO NO15606264A patent/NO119273B/no unknown
- 1964-12-21 BE BE657406D patent/BE657406A/xx unknown
- 1964-12-21 BE BE657405D patent/BE657405A/xx unknown
-
1965
- 1965-03-19 FR FR9866A patent/FR4346M/fr active Active
- 1965-03-19 FR FR9865A patent/FR4345M/fr active Active
Also Published As
Publication number | Publication date |
---|---|
CH449642A (de) | 1968-01-15 |
DK108497C (da) | 1967-12-27 |
BE657405A (ko) | 1965-06-21 |
ES307300A1 (es) | 1965-05-01 |
AT249276B (de) | 1966-09-12 |
ES307302A1 (es) | 1965-05-16 |
GB1092394A (en) | 1967-11-22 |
CH449639A (de) | 1968-01-15 |
IL22642A (en) | 1968-07-25 |
CH446371A (de) | 1967-11-15 |
SE305657B (ko) | 1968-11-04 |
FR4345M (ko) | 1966-08-16 |
NO119274B (ko) | 1970-04-27 |
DK108496C (da) | 1967-12-27 |
SE322779B (ko) | 1970-04-20 |
CH449643A (de) | 1968-01-15 |
AT253687B (de) | 1967-04-25 |
AT261126B (de) | 1968-04-10 |
DK108495C (da) | 1967-12-27 |
CH448118A (de) | 1967-12-15 |
BE657406A (ko) | 1965-06-21 |
DE1445854A1 (de) | 1968-12-05 |
AT249277B (de) | 1966-09-12 |
NL6414820A (ko) | 1965-06-21 |
DK106552C (da) | 1967-02-20 |
CH449640A (de) | 1968-01-15 |
NL6414821A (ko) | 1965-06-21 |
ES307299A1 (es) | 1965-05-16 |
CH449641A (de) | 1968-01-15 |
NO119273B (ko) | 1970-04-27 |
DE1445853A1 (de) | 1968-12-05 |
IL22643A (en) | 1968-07-25 |
ES307301A1 (es) | 1965-05-16 |
FR4346M (ko) | 1966-08-16 |
GB1077711A (en) | 1967-08-02 |