NI201000184A - Composiciones y métodos para tratar el cáncer del seno. - Google Patents
Composiciones y métodos para tratar el cáncer del seno.Info
- Publication number
- NI201000184A NI201000184A NI201000184A NI201000184A NI201000184A NI 201000184 A NI201000184 A NI 201000184A NI 201000184 A NI201000184 A NI 201000184A NI 201000184 A NI201000184 A NI 201000184A NI 201000184 A NI201000184 A NI 201000184A
- Authority
- NI
- Nicaragua
- Prior art keywords
- methods
- breast cancer
- antiprogestin
- instant invention
- low
- Prior art date
Links
- 206010006187 Breast cancer Diseases 0.000 title abstract 3
- 208000026310 Breast neoplasm Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title 1
- 230000000708 anti-progestin effect Effects 0.000 abstract 5
- 239000003418 antiprogestin Substances 0.000 abstract 5
- 102000003676 Glucocorticoid Receptors Human genes 0.000 abstract 2
- 108090000079 Glucocorticoid Receptors Proteins 0.000 abstract 2
- 210000000481 breast Anatomy 0.000 abstract 2
- 239000002379 progesterone receptor modulator Substances 0.000 abstract 2
- 230000035755 proliferation Effects 0.000 abstract 2
- 102000014654 Aromatase Human genes 0.000 abstract 1
- 108010078554 Aromatase Proteins 0.000 abstract 1
- 230000001833 anti-estrogenic effect Effects 0.000 abstract 1
- 230000001076 estrogenic effect Effects 0.000 abstract 1
- 230000003054 hormonal effect Effects 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 238000002657 hormone replacement therapy Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4845208P | 2008-04-28 | 2008-04-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NI201000184A true NI201000184A (es) | 2011-08-10 |
Family
ID=40758440
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NI201000184A NI201000184A (es) | 2008-04-28 | 2010-10-27 | Composiciones y métodos para tratar el cáncer del seno. |
Country Status (21)
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130272956A1 (en) | 2010-06-17 | 2013-10-17 | Franciscus Theodorus Leonardus Brands | (11beta, 17alpha)-11-(4-(2-11C-ACETYL)PHENYL)-17,23-EPOXY-19,24-DINORCHOLA-4,9,20-TRIEN-3-ONE |
| UA113283C2 (xx) * | 2010-12-23 | 2017-01-10 | 19-норстероїди і їх застосування для лікування прогестеронзалежних станів | |
| KR102009007B1 (ko) * | 2011-10-04 | 2019-08-08 | 인비비스 파마슈티컬스 인코포레이티드 | 항-프로게스틴 민감성 종양을 확인하고 치료하기 위한 방법 및 시스템 |
| FR2997628B1 (fr) * | 2012-11-08 | 2015-01-16 | Hra Pharma Lab | Produit de co-micronisation comprenant un modulateur selectif des recepteurs a la progesterone |
| AU2014228990B2 (en) * | 2013-03-15 | 2017-02-02 | Aprecia Pharmaceuticals LLC | Rapid disperse dosage form containing levetiracetam |
| US9339489B2 (en) | 2013-03-15 | 2016-05-17 | Aprecia Pharmaceuticals Company | Rapid disperse dosage form containing levetiracetam |
| HU230381B1 (hu) * | 2014-02-17 | 2016-03-29 | Richter Gedeon Nyrt | Ipari eljárás szteroid intermedier előállítására |
| CN113559075A (zh) | 2014-11-17 | 2021-10-29 | 康泰科思特生物制药公司 | 奥那司酮延长释放组合物和方法 |
| US10308676B2 (en) | 2015-09-25 | 2019-06-04 | Context Biopharma Inc. | Methods of making onapristone intermediates |
| JP2019503353A (ja) | 2015-12-15 | 2019-02-07 | コンテキスト・バイオファーマ・インコーポレイテッド | 非晶質オナプリストン組成物およびそれを作製する方法 |
| KR102744951B1 (ko) | 2016-03-28 | 2024-12-23 | 인사이트 코포레이션 | Tam 억제제로서 피롤로트리아진 화합물 |
| US20180148471A1 (en) | 2016-11-30 | 2018-05-31 | Arno Therapeutics, Inc. | Methods for onapristone synthesis dehydration and deprotection |
| WO2018106914A1 (en) * | 2016-12-09 | 2018-06-14 | Repros Therapeutics Inc. | Oral pharmaceutical compositions comprising an unmicronized selective progesterone receptor as active agent |
| AU2018342471B2 (en) | 2017-09-27 | 2023-08-24 | Incyte Corporation | Salts of pyrrolotriazine derivatives useful as TAM inhibitors |
| ES3031110T3 (en) | 2018-06-29 | 2025-07-04 | Incyte Corp | Formulations of an axl/mer inhibitor |
| RU2679625C1 (ru) * | 2018-11-08 | 2019-02-12 | Ильясов Шамиль Сионович | ПРИМЕНЕНИЕ 3-О-СУЛЬФАМОИЛОКСИ-6-ОКСА-7β-МЕТИЛ-D-ГОМО-8α-ЭСТРА-1,3,5(10)-ТРИЕН-17а-ОНА ДЛЯ ЛЕЧЕНИЯ РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ, ВКЛЮЧАЯ ТРИЖДЫ-НЕГАТИВНУЮ ФОРМУ, И СПОСОБ ЕГО ПОЛУЧЕНИЯ |
| AU2021230385A1 (en) | 2020-03-06 | 2022-09-22 | Incyte Corporation | Combination therapy comprising AXL/MER and PD-1/PD-L1 inhibitors |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2377418A1 (fr) * | 1977-01-13 | 1978-08-11 | Roussel Uclaf | Nouveaux derives steroides 4,9-dieniques 11b-substitues, leur procede de preparation et leur application comme medicaments |
| ZA8231B (en) | 1981-01-09 | 1982-11-24 | Roussel Uclaf | New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained |
| FR2521565B1 (fr) | 1982-02-17 | 1985-07-05 | Dior Sa Parfums Christian | Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees |
| FR2534487B1 (fr) | 1982-10-15 | 1988-06-10 | Dior Christian Parfums | Procede d'homogeneisation de dispersions de phases lamellaires lipidiques hydratees, et suspensions obtenues par ce procede |
| US4780461A (en) | 1983-06-15 | 1988-10-25 | Schering Aktiengesellschaft | 13α-alkyl-gonanes, their production, and pharmaceutical preparations containing same |
| DE3347126A1 (de) | 1983-12-22 | 1985-07-11 | Schering AG, 1000 Berlin und 4709 Bergkamen | 11ss-aryl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate |
| DE3506785A1 (de) | 1985-02-22 | 1986-08-28 | Schering AG, Berlin und Bergkamen, 1000 Berlin | 11ss-n,n-dimethylaminophenyl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate |
| DE3625315A1 (de) | 1986-07-25 | 1988-01-28 | Schering Ag | 11ss-(4-isopropenylphenyl)-estra-4,9-diene, deren herstellung und diese enthaltende pharmazeutische praeparate |
| DE3708942A1 (de) | 1987-03-18 | 1988-09-29 | Schering Ag | 19,11ss-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate |
| US5446178A (en) | 1987-03-18 | 1995-08-29 | Schering Aktiengesellschaft | Process for preparing 19,11β-bridged steroids |
| ATE69820T1 (de) | 1987-04-24 | 1991-12-15 | Akzo Nv | 11-arylestranderivate und 11-arylpregnanderivate. |
| ATE85342T1 (de) | 1987-12-12 | 1993-02-15 | Akzo Nv | 11-arylsteroid-derivate. |
| DE3820948A1 (de) | 1988-06-16 | 1989-12-21 | Schering Ag | 10ss, 11ss-ueberbrueckte steroide |
| DE3822770A1 (de) | 1988-07-01 | 1990-01-04 | Schering Ag | 13-alkyl-11ss-phenylgonane |
| US5077211A (en) | 1988-07-06 | 1991-12-31 | Applied Genetics, Inc. | Purification and administration of dna repair enzymes |
| DE3832303A1 (de) | 1988-09-20 | 1990-04-12 | Schering Ag | 11ss-phenyl-14ssh-steroide |
| DE3917274A1 (de) | 1989-05-24 | 1990-11-29 | Schering Ag | 9(alpha)-hydroxy-19, 11(beta)-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate |
| DE3921059A1 (de) | 1989-06-23 | 1991-01-10 | Schering Ag | 11(beta)-aryl-4-estrene, verfahren zu ihrer herstellung sowie deren verwendung als arzneimittel |
| DE4042007A1 (de) | 1990-12-22 | 1992-06-25 | Schering Ag | 6,7-modifizierte-11(beta)-aryl-4-estrene |
| US5407928A (en) | 1990-08-15 | 1995-04-18 | Schering Aktiengesellschaft | 11β-aryl-gona-4,9-dien-3-ones |
| DE4038128A1 (de) | 1990-11-27 | 1992-06-04 | Schering Ag | 8-en-19, 11(beta)-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate |
| ZA929315B (en) | 1991-12-20 | 1993-05-24 | Akzo Nv | 17-spirofuran-3'-ylidene steroids. |
| DE4216003A1 (de) | 1992-05-12 | 1993-11-18 | Schering Ag | Dissoziierte kompetitive Progesteronantagonisten |
| US5439913A (en) | 1992-05-12 | 1995-08-08 | Schering Aktiengesellschaft | Contraception method using competitive progesterone antagonists and novel compounds useful therein |
| DE4216004B4 (de) | 1992-05-12 | 2008-03-27 | Bayer Schering Pharma Akiengesellschaft | Verwendung kompetitiver Progesteronantagonisten |
| NZ254534A (en) | 1992-07-01 | 1997-12-19 | Ortho Pharma Corp | 1,4,5,6-tetrahydro-pyridazine derivatives, preparation and pharmaceutical compositions thereof |
| DE4332283A1 (de) | 1993-09-20 | 1995-04-13 | Jenapharm Gmbh | Neue 11-Benzaldoximestradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| DE4332284C2 (de) | 1993-09-20 | 1997-05-28 | Jenapharm Gmbh | 11-Benzaldoxim-17beta-methoxy-17alpha-methoxymethyl-estradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| DE4434488A1 (de) | 1994-09-14 | 1996-03-21 | Schering Ag | Steroidester und -amide, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
| US5576310A (en) | 1994-09-20 | 1996-11-19 | Jenapharm Gmbh | 11-benzaldoxime-17β-methoxy-17α-methoxymethyl-estrasdiene derivatives, methods for their production and pharmaceuticals containing such compounds |
| US5688810A (en) | 1994-12-22 | 1997-11-18 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
| EP0806952B1 (de) * | 1995-02-02 | 2003-04-02 | Schering Aktiengesellschaft | Verwendung von kompetitiven progesteronantagonisten für die herstellung von arzneimitteln zur behandlung von dysfunktionellen uterinen blutungen |
| EP0900234B1 (en) * | 1996-05-01 | 2000-07-05 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 21-substituted progesterone derivatives as new antiprogestational agents |
| US6900193B1 (en) * | 1996-05-01 | 2005-05-31 | The United States Of America As Represented By The Department Of Health And Human Services | Structural modification of 19-norprogesterone I: 17-α-substituted-11-β-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents |
| US5753655A (en) | 1996-10-10 | 1998-05-19 | Ortho Pharmaceutical Corporation | 1-arylsulphonyl, arylcarbonyl and arylthiocarbonyl pyridazino derivatives and methods of preparation |
| DE19652408C2 (de) | 1996-12-06 | 2002-04-18 | Schering Ag | Steroidester, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Arzneimitteln |
| DE19706061A1 (de) | 1997-02-07 | 1998-08-13 | Schering Ag | Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette |
| DE19809845A1 (de) | 1998-03-03 | 1999-09-09 | Jenapharm Gmbh | S-substituierte 11beta-Benzaldoxim-estra-4,9-dien-kohlensäurethiolester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen |
| US6391907B1 (en) | 1999-05-04 | 2002-05-21 | American Home Products Corporation | Indoline derivatives |
| US6417214B1 (en) | 1999-05-04 | 2002-07-09 | Wyeth | 3,3-substituted indoline derivatives |
| US6509334B1 (en) | 1999-05-04 | 2003-01-21 | American Home Products Corporation | Cyclocarbamate derivatives as progesterone receptor modulators |
| US6339098B1 (en) | 1999-05-04 | 2002-01-15 | American Home Products Corporation | 2,1-benzisothiazoline 2,2-dioxides |
| US6380235B1 (en) | 1999-05-04 | 2002-04-30 | American Home Products Corporation | Benzimidazolones and analogues |
| US6306851B1 (en) | 1999-05-04 | 2001-10-23 | American Home Products Corporation | Cyclocarbamate and cyclic amide derivatives |
| US6358948B1 (en) | 1999-05-04 | 2002-03-19 | American Home Products Corporation | Quinazolinone and benzoxazine derivatives as progesterone receptor modulators |
| US6369056B1 (en) | 1999-05-04 | 2002-04-09 | American Home Products Corporation | Cyclic urea and cyclic amide derivatives |
| CA2403756C (en) * | 2000-03-17 | 2010-02-09 | Hyun K. Kim | Structural modification of 19-norprogesterone i: 17-.alpha.-substituted, 11-.beta.-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents |
| IN191020B (cg-RX-API-DMAC7.html) * | 2000-03-28 | 2003-09-13 | Dabur Res Foundation | |
| AU1824302A (en) * | 2000-10-18 | 2002-04-29 | Schering Ag | Use of antiprogestins for prophylaxis and treatment of hormone-dependent diseases |
| US8173626B2 (en) * | 2006-03-08 | 2012-05-08 | Danco Laboratories Llc | Methods, dosing regimens and medications using anti-progestational agents for the treatment of disorders |
| JP5379121B2 (ja) * | 2007-04-05 | 2013-12-25 | ユニバーシティ・オブ・カンザス | プルランを含む速溶性医薬組成物 |
| TWI477276B (zh) * | 2008-04-28 | 2015-03-21 | Repros Therapeutics Inc | 抗黃體素給藥方案 |
-
2009
- 2009-04-15 TW TW098112452A patent/TWI539953B/zh not_active IP Right Cessation
- 2009-04-27 WO PCT/US2009/041836 patent/WO2009134723A1/en not_active Ceased
- 2009-04-27 KR KR1020107026594A patent/KR101349737B1/ko not_active Expired - Fee Related
- 2009-04-27 EA EA201071250A patent/EA019224B1/ru not_active IP Right Cessation
- 2009-04-27 MX MX2010011273A patent/MX2010011273A/es not_active Application Discontinuation
- 2009-04-27 MY MYPI2010004824A patent/MY161549A/en unknown
- 2009-04-27 CN CN2009801149792A patent/CN102099040B/zh not_active Expired - Fee Related
- 2009-04-27 EP EP09739525A patent/EP2293798A1/en not_active Withdrawn
- 2009-04-27 US US12/990,210 patent/US20110053900A1/en not_active Abandoned
- 2009-04-27 AU AU2009241360A patent/AU2009241360B2/en not_active Ceased
- 2009-04-27 JP JP2011507559A patent/JP5576362B2/ja not_active Expired - Fee Related
- 2009-04-27 EP EP15179121.7A patent/EP2974772A1/en not_active Withdrawn
- 2009-04-27 CA CA2722637A patent/CA2722637C/en not_active Expired - Fee Related
- 2009-04-27 NZ NZ589534A patent/NZ589534A/xx not_active IP Right Cessation
- 2009-04-27 ME MEP-2010-181A patent/ME01122B/me unknown
- 2009-04-27 BR BRPI0911112A patent/BRPI0911112A2/pt not_active Application Discontinuation
- 2009-04-27 UA UAA201014040A patent/UA101192C2/uk unknown
- 2009-04-28 CL CL2009001011A patent/CL2009001011A1/es unknown
- 2009-04-28 AR ARP090101509A patent/AR071419A1/es unknown
-
2010
- 2010-10-20 IL IL208845A patent/IL208845A/en not_active IP Right Cessation
- 2010-10-26 ZA ZA2010/07648A patent/ZA201007648B/en unknown
- 2010-10-27 NI NI201000184A patent/NI201000184A/es unknown
-
2014
- 2014-05-23 US US14/286,535 patent/US20140343022A1/en not_active Abandoned
-
2016
- 2016-08-03 IL IL247093A patent/IL247093A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2011518883A (ja) | 2011-06-30 |
| BRPI0911112A2 (pt) | 2015-10-06 |
| KR20110003553A (ko) | 2011-01-12 |
| CA2722637A1 (en) | 2009-11-05 |
| WO2009134723A1 (en) | 2009-11-05 |
| WO2009134723A9 (en) | 2010-01-21 |
| US20110053900A1 (en) | 2011-03-03 |
| ZA201007648B (en) | 2011-07-27 |
| EP2974772A1 (en) | 2016-01-20 |
| TWI539953B (zh) | 2016-07-01 |
| AU2009241360A1 (en) | 2009-11-05 |
| CL2009001011A1 (es) | 2009-09-25 |
| EA201071250A1 (ru) | 2011-04-29 |
| EP2293798A1 (en) | 2011-03-16 |
| JP5576362B2 (ja) | 2014-08-20 |
| AR071419A1 (es) | 2010-06-16 |
| EA019224B1 (ru) | 2014-02-28 |
| MY161549A (en) | 2017-04-28 |
| IL208845A0 (en) | 2011-01-31 |
| CA2722637C (en) | 2015-03-10 |
| CN102099040B (zh) | 2013-06-19 |
| AU2009241360B2 (en) | 2012-03-08 |
| UA101192C2 (uk) | 2013-03-11 |
| HK1155084A1 (en) | 2012-05-11 |
| ME01122B (me) | 2013-03-20 |
| US20140343022A1 (en) | 2014-11-20 |
| KR101349737B1 (ko) | 2014-02-07 |
| NZ589534A (en) | 2012-08-31 |
| CN102099040A (zh) | 2011-06-15 |
| IL208845A (en) | 2016-08-31 |
| MX2010011273A (es) | 2010-12-21 |
| TW201002330A (en) | 2010-01-16 |
| IL247093A0 (en) | 2016-09-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NI201000184A (es) | Composiciones y métodos para tratar el cáncer del seno. | |
| Starek-Świechowicz et al. | Endogenous estrogens—breast cancer and chemoprevention | |
| AR068702A1 (es) | Composiciones farmaceuticas | |
| Nappi et al. | Hormonal contraception and bone metabolism: a systematic review | |
| MX363536B (es) | Gel transdermico de progestina/estradiol. | |
| ECSP099349A (es) | Composiciones y métodos para suprimir la proliferación endometrial | |
| AR054175A1 (es) | Nuevos anticuerpos anti-igf-ir y usos de los mismos | |
| PE20211588A1 (es) | Compuestos y sus usos para aliviar sintomas asociados a la menopausia | |
| Królik et al. | The effect of using estrogens in the light of scientific research | |
| Ghazal et al. | Perspective on hormone therapy 10 years after the WHI | |
| BRPI0416275A (pt) | métodos de tratar, controlar ou prevenir um cáncer especìfico e uma doença associada com angiogênese indesejada | |
| MX2023011166A (es) | Compuesto de tetrahidronaftaleno, metodo de preparacion y uso del mismo en medicina. | |
| Montt-Guevara et al. | Estetrol modulates endothelial nitric oxide synthesis in human endothelial cells | |
| DOP2006000223A (es) | Procedimiento para la produccion de una preparacion farmacéutica monofasica para la terapia oral de la hemorragia uterina disfuncional. | |
| Abbas et al. | The protective and therapeutic effects of 5-androstene3β, 17β-diol (ADIOL) in abdominal post-operative adhesions in rat: Suppressing TLR4/NFκB/HMGB1/TGF1 β/α SMA pathway | |
| Rako | Testosterone supplemental therapy after hysterectomy with or without concomitant oophorectomy: estrogen alone is not enough | |
| PA8771801A1 (es) | Heterociclos sulfonilados utiles para la modulacion del receptor de progesterona | |
| PE20051035A1 (es) | Hormonas de administracion transdermica que no necesitan potenciadores de penetracion | |
| Buzdar | Anastrozole as adjuvant therapy for early-stage breast cancer: implications of the ATAC trial | |
| Amori et al. | Primavera: A new therapeutical approach to vulvo‐vaginal atrophy | |
| Galuppi et al. | Local α-tocopherol for acute and short-term vaginal toxicity prevention in patients treated with radiotherapy for gynecologic tumors | |
| CN102783641A (zh) | 一种调节女性荷尔蒙的营养保健品 | |
| DOP2010000017A (es) | Estratrienos 8-beta-sustituidos como estrogenos de accion selectiva | |
| Chawla | Treatment of endometriosis and chronic pelvic pain with letrozole and norethindrone acetate | |
| Stricker | Endocrine effects of breast cancer treatment |