NZ589534A - Combination of aromatase inhibitors and progesterone antagonists in the treatment of breast cancer - Google Patents

Combination of aromatase inhibitors and progesterone antagonists in the treatment of breast cancer

Info

Publication number
NZ589534A
NZ589534A NZ589534A NZ58953409A NZ589534A NZ 589534 A NZ589534 A NZ 589534A NZ 589534 A NZ589534 A NZ 589534A NZ 58953409 A NZ58953409 A NZ 58953409A NZ 589534 A NZ589534 A NZ 589534A
Authority
NZ
New Zealand
Prior art keywords
combination
breast cancer
aromatase inhibitors
treatment
progesterone antagonists
Prior art date
Application number
NZ589534A
Other languages
English (en)
Inventor
Joseph S Podolski
Original Assignee
Repros Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40758440&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ589534(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Repros Therapeutics Inc filed Critical Repros Therapeutics Inc
Publication of NZ589534A publication Critical patent/NZ589534A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NZ589534A 2008-04-28 2009-04-27 Combination of aromatase inhibitors and progesterone antagonists in the treatment of breast cancer NZ589534A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4845208P 2008-04-28 2008-04-28
PCT/US2009/041836 WO2009134723A1 (en) 2008-04-28 2009-04-27 Pregesteron antagonists such as cdb-4124 in the treatment of breast cancer

Publications (1)

Publication Number Publication Date
NZ589534A true NZ589534A (en) 2012-08-31

Family

ID=40758440

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ589534A NZ589534A (en) 2008-04-28 2009-04-27 Combination of aromatase inhibitors and progesterone antagonists in the treatment of breast cancer

Country Status (21)

Country Link
US (2) US20110053900A1 (cg-RX-API-DMAC7.html)
EP (2) EP2293798A1 (cg-RX-API-DMAC7.html)
JP (1) JP5576362B2 (cg-RX-API-DMAC7.html)
KR (1) KR101349737B1 (cg-RX-API-DMAC7.html)
CN (1) CN102099040B (cg-RX-API-DMAC7.html)
AR (1) AR071419A1 (cg-RX-API-DMAC7.html)
AU (1) AU2009241360B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0911112A2 (cg-RX-API-DMAC7.html)
CA (1) CA2722637C (cg-RX-API-DMAC7.html)
CL (1) CL2009001011A1 (cg-RX-API-DMAC7.html)
EA (1) EA019224B1 (cg-RX-API-DMAC7.html)
IL (2) IL208845A (cg-RX-API-DMAC7.html)
ME (1) ME01122B (cg-RX-API-DMAC7.html)
MX (1) MX2010011273A (cg-RX-API-DMAC7.html)
MY (1) MY161549A (cg-RX-API-DMAC7.html)
NI (1) NI201000184A (cg-RX-API-DMAC7.html)
NZ (1) NZ589534A (cg-RX-API-DMAC7.html)
TW (1) TWI539953B (cg-RX-API-DMAC7.html)
UA (1) UA101192C2 (cg-RX-API-DMAC7.html)
WO (1) WO2009134723A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201007648B (cg-RX-API-DMAC7.html)

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UA113283C2 (xx) * 2010-12-23 2017-01-10 19-норстероїди і їх застосування для лікування прогестеронзалежних станів
KR102009007B1 (ko) * 2011-10-04 2019-08-08 인비비스 파마슈티컬스 인코포레이티드 항-프로게스틴 민감성 종양을 확인하고 치료하기 위한 방법 및 시스템
FR2997628B1 (fr) * 2012-11-08 2015-01-16 Hra Pharma Lab Produit de co-micronisation comprenant un modulateur selectif des recepteurs a la progesterone
AU2014228990B2 (en) * 2013-03-15 2017-02-02 Aprecia Pharmaceuticals LLC Rapid disperse dosage form containing levetiracetam
US9339489B2 (en) 2013-03-15 2016-05-17 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
HU230381B1 (hu) * 2014-02-17 2016-03-29 Richter Gedeon Nyrt Ipari eljárás szteroid intermedier előállítására
CN113559075A (zh) 2014-11-17 2021-10-29 康泰科思特生物制药公司 奥那司酮延长释放组合物和方法
US10308676B2 (en) 2015-09-25 2019-06-04 Context Biopharma Inc. Methods of making onapristone intermediates
JP2019503353A (ja) 2015-12-15 2019-02-07 コンテキスト・バイオファーマ・インコーポレイテッド 非晶質オナプリストン組成物およびそれを作製する方法
KR102744951B1 (ko) 2016-03-28 2024-12-23 인사이트 코포레이션 Tam 억제제로서 피롤로트리아진 화합물
US20180148471A1 (en) 2016-11-30 2018-05-31 Arno Therapeutics, Inc. Methods for onapristone synthesis dehydration and deprotection
WO2018106914A1 (en) * 2016-12-09 2018-06-14 Repros Therapeutics Inc. Oral pharmaceutical compositions comprising an unmicronized selective progesterone receptor as active agent
AU2018342471B2 (en) 2017-09-27 2023-08-24 Incyte Corporation Salts of pyrrolotriazine derivatives useful as TAM inhibitors
ES3031110T3 (en) 2018-06-29 2025-07-04 Incyte Corp Formulations of an axl/mer inhibitor
RU2679625C1 (ru) * 2018-11-08 2019-02-12 Ильясов Шамиль Сионович ПРИМЕНЕНИЕ 3-О-СУЛЬФАМОИЛОКСИ-6-ОКСА-7β-МЕТИЛ-D-ГОМО-8α-ЭСТРА-1,3,5(10)-ТРИЕН-17а-ОНА ДЛЯ ЛЕЧЕНИЯ РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ, ВКЛЮЧАЯ ТРИЖДЫ-НЕГАТИВНУЮ ФОРМУ, И СПОСОБ ЕГО ПОЛУЧЕНИЯ
AU2021230385A1 (en) 2020-03-06 2022-09-22 Incyte Corporation Combination therapy comprising AXL/MER and PD-1/PD-L1 inhibitors

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Also Published As

Publication number Publication date
JP2011518883A (ja) 2011-06-30
BRPI0911112A2 (pt) 2015-10-06
KR20110003553A (ko) 2011-01-12
CA2722637A1 (en) 2009-11-05
WO2009134723A1 (en) 2009-11-05
WO2009134723A9 (en) 2010-01-21
US20110053900A1 (en) 2011-03-03
ZA201007648B (en) 2011-07-27
EP2974772A1 (en) 2016-01-20
TWI539953B (zh) 2016-07-01
AU2009241360A1 (en) 2009-11-05
NI201000184A (es) 2011-08-10
CL2009001011A1 (es) 2009-09-25
EA201071250A1 (ru) 2011-04-29
EP2293798A1 (en) 2011-03-16
JP5576362B2 (ja) 2014-08-20
AR071419A1 (es) 2010-06-16
EA019224B1 (ru) 2014-02-28
MY161549A (en) 2017-04-28
IL208845A0 (en) 2011-01-31
CA2722637C (en) 2015-03-10
CN102099040B (zh) 2013-06-19
AU2009241360B2 (en) 2012-03-08
UA101192C2 (uk) 2013-03-11
HK1155084A1 (en) 2012-05-11
ME01122B (me) 2013-03-20
US20140343022A1 (en) 2014-11-20
KR101349737B1 (ko) 2014-02-07
CN102099040A (zh) 2011-06-15
IL208845A (en) 2016-08-31
MX2010011273A (es) 2010-12-21
TW201002330A (en) 2010-01-16
IL247093A0 (en) 2016-09-29

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