MY8500984A - New oxime derivatives of erythromycin a, their preparation,their application as medicaments and the pharmaceutical compositions containing them - Google Patents

New oxime derivatives of erythromycin a, their preparation,their application as medicaments and the pharmaceutical compositions containing them

Info

Publication number
MY8500984A
MY8500984A MY984/85A MY8500984A MY8500984A MY 8500984 A MY8500984 A MY 8500984A MY 984/85 A MY984/85 A MY 984/85A MY 8500984 A MY8500984 A MY 8500984A MY 8500984 A MY8500984 A MY 8500984A
Authority
MY
Malaysia
Prior art keywords
erythromycin
medicaments
preparation
application
pharmaceutical compositions
Prior art date
Application number
MY984/85A
Other languages
English (en)
Inventor
Solange Gouin D Ambrieres
Andre Lutz
Jean-Claude Gasc
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9237443&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY8500984(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of MY8500984A publication Critical patent/MY8500984A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
MY984/85A 1980-01-11 1985-12-30 New oxime derivatives of erythromycin a, their preparation,their application as medicaments and the pharmaceutical compositions containing them MY8500984A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8000566A FR2473525A1 (fr) 1980-01-11 1980-01-11 Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
MY8500984A true MY8500984A (en) 1985-12-31

Family

ID=9237443

Family Applications (1)

Application Number Title Priority Date Filing Date
MY984/85A MY8500984A (en) 1980-01-11 1985-12-30 New oxime derivatives of erythromycin a, their preparation,their application as medicaments and the pharmaceutical compositions containing them

Country Status (25)

Country Link
US (1) US4349545A (pm)
EP (1) EP0033255B1 (pm)
JP (1) JPS56100799A (pm)
KR (1) KR850000964B1 (pm)
AU (1) AU537247B2 (pm)
BG (1) BG61369B2 (pm)
CA (1) CA1162535A (pm)
CY (1) CY1319A (pm)
DE (1) DE3165720D1 (pm)
DK (1) DK157878C (pm)
ES (1) ES498395A0 (pm)
FI (1) FI69473C (pm)
FR (1) FR2473525A1 (pm)
GR (1) GR73103B (pm)
GT (1) GT198500080A (pm)
HK (1) HK586A (pm)
HU (1) HU187760B (pm)
IE (1) IE50680B1 (pm)
IL (1) IL61808A (pm)
LU (1) LU88283I2 (pm)
MY (1) MY8500984A (pm)
NL (1) NL930097I2 (pm)
OA (1) OA06719A (pm)
PT (1) PT72331B (pm)
ZA (1) ZA808108B (pm)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2534588B2 (fr) * 1982-10-15 1985-09-20 Roussel Uclaf Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments
US4526889A (en) * 1982-11-15 1985-07-02 Pfizer Inc. Epimeric azahomoerythromycin A derivative, intermediates and method of use
DK149776C (da) * 1984-01-06 1987-04-21 Orion Yhtymae Oy Antibiotisk virksom erytromycinforbindelse og praeparat indeholdende forbindelsen
JPS60214796A (ja) * 1984-04-06 1985-10-28 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシン類の製法
JPS61103890A (ja) * 1984-10-26 1986-05-22 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシンａ誘導体
US4847242A (en) 1985-03-12 1989-07-11 Beecham Group P.L.C. 11-ether derivatives of erythromycins
JPS61229895A (ja) * 1985-04-03 1986-10-14 Nippon Zeon Co Ltd 保護化デス−ｎ−メチルエリスロマイシン誘導体
US4740502A (en) * 1986-06-20 1988-04-26 Abbott Laboratories Semisynthetic erythromycin antibiotics
EP0260938B1 (en) 1986-09-18 1992-12-09 Taisho Pharmaceutical Co. Ltd Erythromycin a derivatives and method for preparing the same
JP2751385B2 (ja) * 1988-05-19 1998-05-18 大正製薬株式会社 エリスロマイシンａオキシム及びその塩の製造方法
US5075289A (en) * 1988-06-07 1991-12-24 Abbott Laboratories 9-r-azacyclic erythromycin antibiotics
US5302705A (en) * 1989-10-07 1994-04-12 Taisho Pharmaceutical Co., Ltd. 6-O-methylerythromycin a oxime derivatives
US5912331A (en) * 1991-03-15 1999-06-15 Merck & Co., Inc. Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
DE69227713D1 (de) 1991-03-15 1999-01-14 Merck & Co Inc 9-Deoxo-9(Z)-hydroxyiminoerythromycin A und O-Derivate hiervon
US5985844A (en) * 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers
ES2036472B1 (es) * 1991-10-01 1994-03-01 Prodesfarma Sa Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima) (roxitromicina).
US5210235A (en) * 1992-08-26 1993-05-11 Merck & Co., Inc. Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
WO1995028939A1 (fr) * 1994-04-26 1995-11-02 Nobuhiro Narita Composition medicinale servant de medicament contre le cancer bronchopulmonaire 'non a petites cellules'
IT1276901B1 (it) * 1994-12-13 1997-11-03 Zambon Spa Derivati dell'eritromicina a 9-0-ossina dotati di attivita' antibiotica
US5872229A (en) 1995-11-21 1999-02-16 Abbott Laboratories Process for 6-O-alkylation of erythromycin derivatives
FR2760017B1 (fr) * 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
US5929219A (en) 1997-09-10 1999-07-27 Abbott Laboratories 9-hydrazone and 9-azine erythromycin derivatives and a process of making the same
PT102202B (pt) * 1998-09-10 2001-04-30 Hovione Sociedade Quimica S A Processo para a purificacao de roxitromicina
IN190782B (pm) * 1998-09-30 2003-08-23 Max India Ltd
EP1004591B1 (en) * 1998-11-24 2003-04-09 Max India Limited Process for preparing roxithromycin and derivatives thereof
IL150227A0 (en) * 1999-12-16 2002-12-01 Teva Pharma Processes for preparing clarithromycin polymorphs and novel polymorph iv
PT1280535E (pt) * 2000-01-11 2005-04-29 Teva Pharma Processos para a preparacao de polimorfos de claritromicina
YU64202A (sh) * 2000-02-29 2005-03-15 Teva Pharmaceutical Industries Ltd. Postupak za pripremanje klaritromicina i intermedijera klaritromicina, klaritromicina u osnovi bez oksima i farmaceutskog preparata koji ga sadrži
HRP20020885B1 (en) 2002-11-11 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. SUBSTITUTED 9a-N-{N'-[4-(SULFONYL)PHENYLCARBAMOYL]}DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-O-DESOZAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHRONOLIDE A
HRP20020991A2 (en) 2002-12-12 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. N"-Substituted 9a-N-(N'-carbamoyl-Gamma-aminopropyl), 9a-N-(N'? -thiocarbamoyl-Gamma-aminopropyl), 9a-N-(N'-((Beta-cyanoethyl)-N'-carbamoyl-Gamma? -aminopropyl) and 9a-N-(N'-(Beta-cyanoethyl)-N'-thiocarbamoyl-Gamma? -aminopropyl) derivatives of 9-de
AU2003271408B2 (en) * 2002-12-31 2008-07-17 Alembic Limited A process for the purification of roxithromycin
RU2222333C1 (ru) * 2003-03-06 2004-01-27 Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" Фармацевтическая композиция с антибактериальной активностью и способ ее получения
JP2010501541A (ja) 2006-08-24 2010-01-21 ウォックハート リサーチ センター 抗菌活性を有する新規マクロライド及びケトライド
US20090005326A1 (en) * 2007-06-26 2009-01-01 Idexx Laboratories, Inc. Single dose roxithromycin
US9175031B2 (en) 2010-12-09 2015-11-03 Wockhardt Limited Ketolide compounds
US9206214B2 (en) 2011-03-01 2015-12-08 Wockhardt Ltd. Process for preparation of ketolide intermediates
US8993739B2 (en) 2011-03-22 2015-03-31 Wockhardt Ltd. Process for preparation of ketolide compounds
CN102219816A (zh) * 2011-05-12 2011-10-19 浙江国邦药业有限公司 一种罗红霉素的纯化方法
PL222631B1 (pl) 2012-11-14 2016-08-31 Gdański Univ Medyczny Kompozycja farmaceutyczna zawierająca roksytromycynę, sposób jej wytwarzania oraz zastosowanie medyczne tej kompozycji i produkt leczniczy zawierający kompozycję
CN104163840A (zh) * 2013-08-30 2014-11-26 郑州后羿制药有限公司 一种罗红霉素的精制方法
FR3049861A1 (fr) 2016-04-07 2017-10-13 Univ Claude Bernard Lyon Nouvelles compositions antivirales pour le traitement de la grippe

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU31319B (en) * 1967-08-03 1973-04-30 Pliva Pharm & Chem Works Postupak za dobijanje acil derivata eritromicin oksima
US3869444A (en) * 1972-10-10 1975-03-04 Abbott Lab Esters of erythromycin oxime
ES434842A1 (es) * 1975-02-19 1976-12-01 Andreu Sa Dr Procedimiento para la preparacion de esteres de la oxima deeritromicina.
DK139522C (da) * 1975-04-07 1979-08-20 Thomae Gmbh Dr K Analogifremgangsmaade til fremstilling af 9-iminoalkylamino-erythromyciner eller syreadditionssalte deraf
DE2515076A1 (de) * 1975-04-07 1976-10-28 Thomae Gmbh Dr K Neue erythromycinderivate, deren salze und verfahren zu ihrer herstellung
DE2515077A1 (de) * 1975-04-07 1976-10-28 Thomae Gmbh Dr K Neue 9-alkylidenamino-erythromycine, ihre salze und verfahren zu ihrer herstellung
DE2750288A1 (de) * 1977-11-10 1979-05-17 Thomae Gmbh Dr K Neue 9-(omega-heteroarylamino- alkylamino)-erythromycine, ihre salze, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
DE3165720D1 (en) 1984-10-04
PT72331B (fr) 1982-07-23
IE50680B1 (en) 1986-06-11
FR2473525B1 (pm) 1983-04-15
US4349545A (en) 1982-09-14
JPS56100799A (en) 1981-08-12
IL61808A0 (en) 1981-01-30
AU537247B2 (en) 1984-06-14
HU187760B (en) 1986-02-28
FI69473C (fi) 1986-02-10
DK157878B (da) 1990-02-26
CA1162535A (fr) 1984-02-21
DK7881A (da) 1981-07-12
OA06719A (fr) 1982-06-30
ZA808108B (en) 1982-01-27
FI810042L (fi) 1981-07-12
ES8200702A1 (es) 1981-11-01
EP0033255B1 (fr) 1984-08-29
LU88283I2 (fr) 1994-09-09
EP0033255A1 (fr) 1981-08-05
ES498395A0 (es) 1981-11-01
GR73103B (pm) 1984-02-02
GT198500080A (es) 1987-03-06
FI69473B (fi) 1985-10-31
NL930097I1 (nl) 1993-10-01
KR830005258A (ko) 1983-08-03
IE810046L (en) 1981-07-11
DK157878C (da) 1990-07-30
JPS6237639B2 (pm) 1987-08-13
NL930097I2 (nl) 1995-04-03
PT72331A (fr) 1981-02-01
AU6613181A (en) 1981-07-16
CY1319A (en) 1986-03-28
HK586A (en) 1986-01-10
BG61369B2 (bg) 1997-06-30
IL61808A (en) 1986-12-31
FR2473525A1 (fr) 1981-07-17
KR850000964B1 (ko) 1985-07-02

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