MY189774A - Atropine-containing aqueous composition - Google Patents

Atropine-containing aqueous composition

Info

Publication number
MY189774A
MY189774A MYPI2018001914A MYPI2018001914A MY189774A MY 189774 A MY189774 A MY 189774A MY PI2018001914 A MYPI2018001914 A MY PI2018001914A MY PI2018001914 A MYPI2018001914 A MY PI2018001914A MY 189774 A MY189774 A MY 189774A
Authority
MY
Malaysia
Prior art keywords
buffer
atropine
aqueous composition
containing aqueous
aminocarboxylate
Prior art date
Application number
MYPI2018001914A
Other languages
English (en)
Inventor
Donald Tan
Roger Beuerman
Hiroyuki Asada
Kyohei Takahashi
Koji Sakanaka
Takashi Morimoto
Toyomi Fujisawa
Original Assignee
Univ Nanyang Tech
Santen Pharmaceutical Co Ltd
Singapore Health Serv Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=60411416&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY189774(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Nanyang Tech, Santen Pharmaceutical Co Ltd, Singapore Health Serv Pte Ltd filed Critical Univ Nanyang Tech
Publication of MY189774A publication Critical patent/MY189774A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/08—Mydriatics or cycloplegics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Photolithography (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
MYPI2018001914A 2016-05-25 2017-05-24 Atropine-containing aqueous composition MY189774A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SG10201604200P 2016-05-25
PCT/JP2017/019423 WO2017204262A1 (en) 2016-05-25 2017-05-24 Atropine-containing aqueous composition

Publications (1)

Publication Number Publication Date
MY189774A true MY189774A (en) 2022-03-04

Family

ID=60411416

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2018001914A MY189774A (en) 2016-05-25 2017-05-24 Atropine-containing aqueous composition

Country Status (15)

Country Link
US (2) US20210267885A1 (enExample)
EP (2) EP3463360B1 (enExample)
JP (6) JP6590860B2 (enExample)
KR (4) KR102580933B1 (enExample)
CN (3) CN117205210A (enExample)
AR (1) AR108591A1 (enExample)
CA (1) CA3023149C (enExample)
EA (1) EA201892703A1 (enExample)
ES (1) ES2929368T3 (enExample)
MY (1) MY189774A (enExample)
PH (1) PH12018502421A1 (enExample)
SG (1) SG11201809822SA (enExample)
TW (3) TWI791438B (enExample)
UA (1) UA126195C2 (enExample)
WO (1) WO2017204262A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016172712A2 (en) * 2015-04-23 2016-10-27 Sydnexis, Inc. Ophthalmic composition
US9421199B2 (en) 2014-06-24 2016-08-23 Sydnexis, Inc. Ophthalmic composition
EP3302426A4 (en) 2015-05-29 2018-12-05 Sydnexis, Inc. D2o stabilized pharmaceutical formulations
KR20200007769A (ko) 2017-02-21 2020-01-22 싱가포르 헬스 서비시즈 피티이 엘티디 아트로핀을 포함하는 근시의 발병을 방지 또는 지연하기 위한 조성물 및 방법
US10251875B2 (en) 2017-05-11 2019-04-09 Nevakar Inc. Atropine pharmaceutical compositions
CN110934816B (zh) * 2018-09-25 2022-04-08 沈阳兴齐眼科医院有限公司 一种提高低浓度阿托品眼用制剂稳定性的方法
CN110934869B (zh) * 2018-09-25 2023-07-04 沈阳兴齐眼药股份有限公司 一种阿托品药物组合物和药盒产品
EP3701938B8 (en) 2019-03-01 2024-02-21 Medivis S.R.L. Ophthalmic formulations based on atropine
TWI907473B (zh) * 2020-08-04 2025-12-11 日商參天製藥股份有限公司 治療近視、預防近視及/或抑制近視進展之藥劑
AU2021362374A1 (en) * 2020-10-14 2023-05-25 Santen Pharmaceutical Co., Ltd. Stable pharmaceutical composition
EP4237421A4 (en) 2020-11-02 2024-11-06 Trethera Corporation CRYSTALLINE FORMS OF A DEOXYCYTIDINE KINASE INHIBITOR AND THEIR USES
WO2022130337A1 (en) * 2020-12-17 2022-06-23 Sun Pharmaceutical Industries Limited An aqueous sterile solution of atropine for ophthalmic use
EP4088714A1 (en) 2021-05-10 2022-11-16 Warszawskie Zaklady Farmaceutyczne Polfa S.A. Ophthalmic pharmaceutical composition comprising atropine
EP4088713A1 (en) 2021-05-10 2022-11-16 Warszawskie Zaklady Farmaceutyczne Polfa S.A. Ophthalmic pharmaceutical composition comprising atropine
US20230120997A1 (en) * 2021-10-18 2023-04-20 Ocular Science, Inc. Compositions and methods for myopia control and orthokeratology lenses treatment
CN114129511A (zh) * 2021-12-07 2022-03-04 河南润弘制药股份有限公司 一种具有改进稳定性的硫酸阿托品注射液
CN119110721A (zh) * 2022-09-11 2024-12-10 爱尔康公司 包含苄基阿托品的水性药物组合物及其用途
JP7665073B1 (ja) 2024-04-05 2025-04-18 ロート製薬株式会社 容器に収容してなる眼科用組成物
JP7723851B1 (ja) * 2024-11-22 2025-08-14 参天製薬株式会社 アトロピン含有水性医薬組成物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2617508B2 (ja) * 1988-02-05 1997-06-04 エーザイ株式会社 安定なジフェンヒドラミン含有水溶液
US5612027A (en) * 1995-04-18 1997-03-18 Galin; Miles A. Controlled release of miotic and mydriatic drugs in the anterior chamber
JP3166002B2 (ja) * 1997-01-27 2001-05-14 日本車輌製造株式会社 自動車の洗浄装置
US20030096831A1 (en) 2000-01-18 2003-05-22 Stone Richard A. Ocular growth and nicotinic antagonists
BR0210013A (pt) * 2001-05-25 2004-08-10 Valley Forge Pharmaceuticals Gel oftálmico de pirenzepina
US20070254914A1 (en) * 2006-05-01 2007-11-01 Non-Profit Organization Chang Gung Memorial Hospital Low-concentration atropine solution for preventing myopia progression and preparing method thereof
JP2007308398A (ja) * 2006-05-17 2007-11-29 Chang Gung Memorial Hospital 目薬、及びその製造方法
CA2688811A1 (en) * 2007-05-21 2008-11-27 Neuroptix Corporation Ophthalmic formulations of amyloid-beta contrast agents and methods of use thereof
CN101327216A (zh) * 2007-06-22 2008-12-24 肖正连 一种硫酸阿托品眼用即型凝胶
WO2012161655A1 (en) * 2011-05-23 2012-11-29 Singapore Health Services Pte Ltd Composition and/or method for reducing and/or preventing myopia progression comprising atropine
US9421199B2 (en) * 2014-06-24 2016-08-23 Sydnexis, Inc. Ophthalmic composition
US20160009705A1 (en) 2014-06-24 2016-01-14 Sydnexis, Inc. Ophthalmic composition
CN104983739B (zh) * 2015-06-25 2018-01-16 成都乾坤动物药业股份有限公司 一种多功能药物组合及其制备方法和应用
JP2017102939A (ja) * 2016-12-26 2017-06-08 株式会社プロフィールド オーサリング装置、オーサリング方法、およびプログラム
US10251875B2 (en) * 2017-05-11 2019-04-09 Nevakar Inc. Atropine pharmaceutical compositions

Also Published As

Publication number Publication date
US20240307305A1 (en) 2024-09-19
JP2023058574A (ja) 2023-04-25
TWI849355B (zh) 2024-07-21
UA126195C2 (uk) 2022-08-31
KR102580933B1 (ko) 2023-09-19
CN109310687A (zh) 2019-02-05
JP7224390B2 (ja) 2023-02-17
ES2929368T3 (es) 2022-11-28
TW202325296A (zh) 2023-07-01
KR20230141882A (ko) 2023-10-10
EP3463360A4 (en) 2020-01-29
CN117205210A (zh) 2023-12-12
KR20250067951A (ko) 2025-05-15
JP2025176149A (ja) 2025-12-03
JP6886502B2 (ja) 2021-06-16
KR20190013877A (ko) 2019-02-11
CN117205209A (zh) 2023-12-12
CA3023149C (en) 2024-07-02
CN109310687B (zh) 2023-10-20
WO2017204262A1 (en) 2017-11-30
KR20220154842A (ko) 2022-11-22
TWI791438B (zh) 2023-02-11
JP2025084921A (ja) 2025-06-03
EP4112055A1 (en) 2023-01-04
CA3023149A1 (en) 2017-11-30
KR102804061B1 (ko) 2025-05-07
EP3463360A1 (en) 2019-04-10
JP2018021007A (ja) 2018-02-08
JP6590860B2 (ja) 2019-10-16
EA201892703A1 (ru) 2019-04-30
EP3463360B1 (en) 2022-08-31
TW202206070A (zh) 2022-02-16
TW201808289A (zh) 2018-03-16
US20210267885A1 (en) 2021-09-02
JP2020007356A (ja) 2020-01-16
JP2021120404A (ja) 2021-08-19
PH12018502421A1 (en) 2019-09-30
AR108591A1 (es) 2018-09-05
TWI874894B (zh) 2025-03-01
SG11201809822SA (en) 2018-12-28

Similar Documents

Publication Publication Date Title
PH12018502421A1 (en) Atropine-containing aqueous composition
MX2022012110A (es) Sistemas crispr clase ii tipo ii.
WO2019014395A8 (en) GENERATION OF WATER-SOLUBLE CANNABINOID COMPOUNDS IN PLANT CELL SUSPENSION YEAST AND CROPS AND MATERIAL COMPOSITIONS
WO2018175636A3 (en) Compositions and methods for immunooncology
SA519410453B1 (ar) تركيبات وطرق للتحكم في أنظمة حمضية قوية
MY198483A (en) Latex composition
MX2017008937A (es) Carbonato de calcio tratado en la superficie con estabilidad mejorada en ambientes con un ph de 4.5 a 7.
MX2017015132A (es) Hidrogel que porta inhibidor de hidrato.
PH12017500286B1 (en) Lithium-containing calcium aluminate phosphate cement admixtures
EP4309732A3 (en) Modulators of pcsk9 expression
WO2015173631A3 (en) Compositions and methods for micropatterning superhydrophobic surfaces
WO2017087912A3 (en) Ratiometric biosensors and non-geometrically modulated fret
MX2020013732A (es) Metodos de fabricacion de composiciones de aminoacidos.
EP4696364A3 (en) A system for planning and/or providing neuromodulation
WO2019013532A3 (ko) 아세토하이드록시산 신타아제 변이체, 이를 포함하는 미생물 또는 이를 이용하는 l-분지쇄 아미노산 생산 방법
PH12018502233A1 (en) ErbB INHIBITORS AND USES THEREOF
TN2020000050A1 (en) Novel phenylpyridine derivative and pharmaceutical composition containing same
WO2017181163A3 (en) Methods and compositions for detection and diagnosis of breast cancer
EP4674401A3 (en) Container accommodating an aqueous ophthalmic composition comprising delgocitinib
PH12020551154A1 (en) Method for suppressing discoloration of external composition containing adenosine phosphate and tranexamic acid
WO2018166993A3 (en) PYRAZOLOCHLOROPHENYL COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF
ZA202001315B (en) Aqueous spray composition
ZA202205170B (en) Process and intermediate for the preparation of oxetan-2-ylmethanamine
MX2017001907A (es) Composicion que comprende huevecillos de artropodos.
PH12019501977B1 (en) Additive composition for ground improvement