MY189519A - Carbidopa and l-dopa prodrugs and methods of use - Google Patents

Carbidopa and l-dopa prodrugs and methods of use

Info

Publication number
MY189519A
MY189519A MYPI2017701367A MYPI2017701367A MY189519A MY 189519 A MY189519 A MY 189519A MY PI2017701367 A MYPI2017701367 A MY PI2017701367A MY PI2017701367 A MYPI2017701367 A MY PI2017701367A MY 189519 A MY189519 A MY 189519A
Authority
MY
Malaysia
Prior art keywords
carbidopa
methods
prodrug
dopa
prodrugs
Prior art date
Application number
MYPI2017701367A
Other languages
English (en)
Inventor
Cardinal-David Benoit
S Chan Vincent
E Dempah Kassibla
P Enright Brian
F Henry Rodger
Ho Raimundo
Huang Ye
D Huters Alexander
C Klix Russell
W Krabbe Scott
R Kym Philip
Lao Yanbin
Lou Xiaochun
E Mackey Sean
A Matulenko Mark
T Mayer Peter
P Miller Christopher
Stambuli James
A Voight Eric
Wang Zhi
G Zhang Geoff
J Stella Valentino
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54478240&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY189519(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of MY189519A publication Critical patent/MY189519A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/094—Esters of phosphoric acids with arylalkanols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/02—Compounds containing any of the groups, e.g. carbazates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/24—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of a carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MYPI2017701367A 2014-10-21 2015-10-21 Carbidopa and l-dopa prodrugs and methods of use MY189519A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462066771P 2014-10-21 2014-10-21
PCT/US2015/056686 WO2016065019A1 (en) 2014-10-21 2015-10-21 Carbidopa and l-dopa prodrugs and their use to treat parkinson's disease

Publications (1)

Publication Number Publication Date
MY189519A true MY189519A (en) 2022-02-16

Family

ID=54478240

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2017701367A MY189519A (en) 2014-10-21 2015-10-21 Carbidopa and l-dopa prodrugs and methods of use

Country Status (37)

Country Link
US (7) US9446059B2 (https=)
EP (3) EP3569587A1 (https=)
JP (6) JP6567049B2 (https=)
KR (3) KR20230066484A (https=)
CN (4) CN107206013A (https=)
AR (1) AR102389A1 (https=)
AU (4) AU2015335941B2 (https=)
BR (1) BR112017008198B1 (https=)
CA (1) CA2965379A1 (https=)
CY (2) CY1121826T1 (https=)
DK (1) DK3209302T3 (https=)
ES (1) ES2739536T3 (https=)
FI (1) FIC20230014I1 (https=)
FR (1) FR23C1035I2 (https=)
HR (1) HRP20191285T1 (https=)
HU (2) HUE044115T2 (https=)
IL (3) IL251829B (https=)
LT (2) LT3209302T (https=)
LU (1) LUC00304I2 (https=)
MX (2) MX381069B (https=)
MY (1) MY189519A (https=)
NL (1) NL301224I2 (https=)
NO (1) NO2023013I1 (https=)
PH (1) PH12017500746B1 (https=)
PL (1) PL3209302T3 (https=)
PT (1) PT3209302T (https=)
RS (1) RS58972B1 (https=)
RU (2) RU2743347C2 (https=)
SA (1) SA521421115B1 (https=)
SG (1) SG11201703170RA (https=)
SI (1) SI3209302T1 (https=)
SM (1) SMT201900376T1 (https=)
TR (1) TR201908296T4 (https=)
TW (2) TWI718999B (https=)
UA (1) UA120437C2 (https=)
WO (1) WO2016065019A1 (https=)
ZA (1) ZA201702760B (https=)

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US11130775B2 (en) 2019-05-20 2021-09-28 H. Lundbeck A/S Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
CN113727712B (zh) 2019-05-21 2024-11-15 H.隆德贝克有限公司 用于治疗帕金森病的儿茶酚胺氨基甲酸酯前药
EP3972971A1 (en) 2019-05-21 2022-03-30 H. Lundbeck A/S New catecholamine prodrugs for use in the treatment of parkinson's diseases
JP7562562B2 (ja) 2019-05-21 2024-10-07 ハー・ルンドベック・アクチエゼルスカベット パーキンソン病の治療に使用するための新規なカテコールアミンプロドラッグ
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Publication number Publication date
US20230106081A1 (en) 2023-04-06
CA2965379A1 (en) 2016-04-28
FR23C1035I2 (fr) 2025-04-18
AU2023210650A1 (en) 2023-08-24
JP6750076B2 (ja) 2020-09-02
UA120437C2 (uk) 2019-12-10
RU2017117413A3 (https=) 2019-05-30
TWI718999B (zh) 2021-02-21
CN111454290A (zh) 2020-07-28
AR102389A1 (es) 2017-02-22
CN107206013A (zh) 2017-09-26
KR20240113982A (ko) 2024-07-23
CY2023010I2 (el) 2023-06-09
MX381069B (es) 2025-03-12
FIC20230014I1 (fi) 2023-03-31
TW202131931A (zh) 2021-09-01
BR112017008198B1 (pt) 2021-02-09
US20180079762A1 (en) 2018-03-22
KR102537018B1 (ko) 2023-05-30
NL301224I2 (nl) 2023-08-16
US20160106765A1 (en) 2016-04-21
LT3209302T (lt) 2019-06-10
PH12017500746B1 (en) 2021-12-15
HUS2300009I1 (hu) 2023-03-28
PH12017500746A1 (en) 2017-10-30
JP6932227B2 (ja) 2021-09-08
CY2023010I1 (el) 2023-06-09
IL268885A (en) 2019-10-31
NL301224I1 (https=) 2023-03-29
WO2016065019A1 (en) 2016-04-28
MX2017005236A (es) 2017-07-26
IL251829A0 (en) 2017-06-29
RU2743347C2 (ru) 2021-02-17
PL3209302T3 (pl) 2019-10-31
HUE044115T2 (hu) 2019-10-28
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US20160362431A1 (en) 2016-12-15
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DK3209302T3 (da) 2019-05-13
US10730895B2 (en) 2020-08-04
AU2021201414A1 (en) 2021-03-25
RU2017117413A (ru) 2018-11-26
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IL251829B (en) 2019-09-26
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NO2023013I1 (no) 2023-03-20
AU2015335941B2 (en) 2021-04-01
US20190375770A1 (en) 2019-12-12
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AU2021201414B2 (en) 2023-05-11
CN111494395B (zh) 2024-06-21
MX2021003840A (es) 2022-06-30
AU2025238004A1 (en) 2025-10-16
SI3209302T1 (sl) 2019-06-28
RS58972B1 (sr) 2019-08-30
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CY1121826T1 (el) 2020-07-31
JP2025118978A (ja) 2025-08-13
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US11091507B2 (en) 2021-08-17
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US20220153765A1 (en) 2022-05-19
US20200262852A1 (en) 2020-08-20
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JP7688087B2 (ja) 2025-06-03
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CN111494395A (zh) 2020-08-07
RU2021103000A (ru) 2021-03-01
MX393568B (es) 2025-03-24
JP2020189864A (ja) 2020-11-26
JP2023174770A (ja) 2023-12-08
US9446059B2 (en) 2016-09-20
AU2015335941A1 (en) 2017-05-04
FR23C1035I1 (fr) 2023-12-08
TR201908296T4 (tr) 2019-06-21
BR112017008198A2 (pt) 2017-12-26
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SMT201900376T1 (it) 2019-09-09
TWI755257B (zh) 2022-02-11
KR20170071599A (ko) 2017-06-23
CN111454290B (zh) 2022-12-23
EP3209302A1 (en) 2017-08-30
SG11201703170RA (en) 2017-05-30
NZ730996A (en) 2024-04-26
KR20230066484A (ko) 2023-05-15
SA521421115B1 (ar) 2022-03-01
US10174061B2 (en) 2019-01-08
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