MY179505A - Recombinant binding proteins and their use - Google Patents

Recombinant binding proteins and their use

Info

Publication number
MY179505A
MY179505A MYPI2017703637A MYPI2017703637A MY179505A MY 179505 A MY179505 A MY 179505A MY PI2017703637 A MYPI2017703637 A MY PI2017703637A MY PI2017703637 A MYPI2017703637 A MY PI2017703637A MY 179505 A MY179505 A MY 179505A
Authority
MY
Malaysia
Prior art keywords
ankyrin repeat
designed ankyrin
binding proteins
recombinant binding
binding specificity
Prior art date
Application number
MYPI2017703637A
Other languages
English (en)
Inventor
Bakker Talitha
T Stumpp Michael
Kaspar Binz Hans
Phillips Douglas
DOLADO Ignacio
Forrer Patrik
W Merz Frieder
Sonderegger Ivo
Steiner Daniel
Gulotti- Georgieva Maya
Abram Saliba Johan
Original Assignee
Molecular Partners Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molecular Partners Ag filed Critical Molecular Partners Ag
Publication of MY179505A publication Critical patent/MY179505A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4703Inhibitors; Suppressors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • C07K14/765Serum albumin, e.g. HSA
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2318/00Antibody mimetics or scaffolds
    • C07K2318/20Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/31Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
MYPI2017703637A 2015-04-02 2016-04-01 Recombinant binding proteins and their use MY179505A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15162502 2015-04-02
EP15162511 2015-04-02

Publications (1)

Publication Number Publication Date
MY179505A true MY179505A (en) 2020-11-09

Family

ID=55650423

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2017703637A MY179505A (en) 2015-04-02 2016-04-01 Recombinant binding proteins and their use

Country Status (20)

Country Link
US (3) US9458211B1 (cg-RX-API-DMAC7.html)
EP (2) EP4272838A3 (cg-RX-API-DMAC7.html)
JP (1) JP6552636B2 (cg-RX-API-DMAC7.html)
KR (2) KR20220109488A (cg-RX-API-DMAC7.html)
CN (1) CN107454904A (cg-RX-API-DMAC7.html)
AU (3) AU2016240220B2 (cg-RX-API-DMAC7.html)
BR (1) BR112017020986A2 (cg-RX-API-DMAC7.html)
CA (1) CA2979602C (cg-RX-API-DMAC7.html)
CL (1) CL2017002454A1 (cg-RX-API-DMAC7.html)
CO (1) CO2017009954A2 (cg-RX-API-DMAC7.html)
ES (1) ES2953482T3 (cg-RX-API-DMAC7.html)
IL (2) IL276944B (cg-RX-API-DMAC7.html)
MX (2) MX2022008302A (cg-RX-API-DMAC7.html)
MY (1) MY179505A (cg-RX-API-DMAC7.html)
NZ (1) NZ735803A (cg-RX-API-DMAC7.html)
PH (1) PH12017501792B1 (cg-RX-API-DMAC7.html)
RU (1) RU2769470C2 (cg-RX-API-DMAC7.html)
SA (1) SA517390092B1 (cg-RX-API-DMAC7.html)
SG (1) SG11201707606RA (cg-RX-API-DMAC7.html)
WO (1) WO2016156596A1 (cg-RX-API-DMAC7.html)

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CA3139164A1 (en) * 2019-06-04 2020-12-10 Molecular Partners Ag Recombinant fap binding proteins and their use
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JP2023506763A (ja) 2019-12-11 2023-02-20 モレキュラー パートナーズ アクチェンゲゼルシャフト 組換えペプチド-mhc複合体結合タンパク質並びにそれらの生成及び使用
TW202208404A (zh) * 2020-05-06 2022-03-01 瑞士商分子組合公司 新穎錨蛋白重複結合蛋白質及其用途
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CN114957426B (zh) * 2022-06-02 2023-05-16 华南师范大学 Sp6rars及其在防治蜚蠊目昆虫中的应用
CN119731200A (zh) 2022-08-01 2025-03-28 分子合作伙伴股份公司 经电荷修饰设计的重复结构域及其用途
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Also Published As

Publication number Publication date
CA2979602C (en) 2022-12-20
MX393655B (es) 2025-03-24
EP3277711B1 (en) 2023-06-07
EP4272838A2 (en) 2023-11-08
US20160362453A1 (en) 2016-12-15
SA517390092B1 (ar) 2022-03-03
IL254788A0 (en) 2017-12-31
AU2021286418A1 (en) 2022-01-20
EP3277711A1 (en) 2018-02-07
AU2016240220A1 (en) 2017-10-19
EP3277711C0 (en) 2023-06-07
JP2018511327A (ja) 2018-04-26
AU2021286418B2 (en) 2024-01-04
US11332501B2 (en) 2022-05-17
KR20170131515A (ko) 2017-11-29
AU2020201264A1 (en) 2020-03-12
ES2953482T3 (es) 2023-11-13
RU2017134456A (ru) 2019-04-03
EP3277711B9 (en) 2023-08-16
RU2769470C2 (ru) 2022-04-01
PH12017501792B1 (en) 2022-07-20
KR20220109488A (ko) 2022-08-04
MX2017012485A (es) 2018-04-11
RU2017134456A3 (cg-RX-API-DMAC7.html) 2019-10-08
BR112017020986A2 (pt) 2018-08-14
SG11201707606RA (en) 2017-10-30
IL254788B (en) 2020-09-30
CL2017002454A1 (es) 2018-05-25
US20190263869A1 (en) 2019-08-29
IL276944B (en) 2022-07-01
NZ735803A (en) 2021-12-24
US20160289285A1 (en) 2016-10-06
AU2016240220B2 (en) 2019-11-21
CO2017009954A2 (es) 2018-02-20
US9458211B1 (en) 2016-10-04
MX2022008302A (es) 2023-02-28
IL276944A (en) 2020-10-29
PH12017501792A1 (en) 2019-01-21
JP6552636B2 (ja) 2019-07-31
CA2979602A1 (en) 2016-10-06
HK1244009A1 (en) 2018-07-27
CN107454904A (zh) 2017-12-08
US10155791B2 (en) 2018-12-18
WO2016156596A1 (en) 2016-10-06
KR102427117B1 (ko) 2022-07-29
EP4272838A3 (en) 2024-01-10

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