SG11201408196RA - Designed ankyrin repeat proteins binding to platelet-derived growth factor - Google Patents
Designed ankyrin repeat proteins binding to platelet-derived growth factorInfo
- Publication number
- SG11201408196RA SG11201408196RA SG11201408196RA SG11201408196RA SG11201408196RA SG 11201408196R A SG11201408196R A SG 11201408196RA SG 11201408196R A SG11201408196R A SG 11201408196RA SG 11201408196R A SG11201408196R A SG 11201408196RA SG 11201408196R A SG11201408196R A SG 11201408196RA
- Authority
- SG
- Singapore
- Prior art keywords
- platelet
- growth factor
- derived growth
- ankyrin repeat
- repeat proteins
- Prior art date
Links
- 108700022150 Designed Ankyrin Repeat Proteins Proteins 0.000 title 1
- 102000010780 Platelet-Derived Growth Factor Human genes 0.000 title 1
- 108010038512 Platelet-Derived Growth Factor Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/49—Platelet-derived growth factor [PDGF]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2318/00—Antibody mimetics or scaffolds
- C07K2318/20—Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12174020 | 2012-06-28 | ||
| PCT/EP2013/063488 WO2014001442A1 (en) | 2012-06-28 | 2013-06-27 | Designed ankyrin repeat proteins binding to platelet-derived growth factor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201408196RA true SG11201408196RA (en) | 2015-03-30 |
Family
ID=48699826
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201408196RA SG11201408196RA (en) | 2012-06-28 | 2013-06-27 | Designed ankyrin repeat proteins binding to platelet-derived growth factor |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US9163070B2 (en) |
| EP (1) | EP2867360B1 (en) |
| JP (1) | JP2015522576A (en) |
| KR (1) | KR20150023957A (en) |
| CN (1) | CN104508129A (en) |
| AU (1) | AU2013283296A1 (en) |
| BR (1) | BR112014032316A2 (en) |
| CA (1) | CA2877584A1 (en) |
| HK (1) | HK1209156A1 (en) |
| IL (1) | IL236428A0 (en) |
| IN (1) | IN2014MN02522A (en) |
| MX (1) | MX2014015825A (en) |
| RU (1) | RU2014150224A (en) |
| SG (1) | SG11201408196RA (en) |
| WO (1) | WO2014001442A1 (en) |
| ZA (1) | ZA201408872B (en) |
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| TWI510246B (en) | 2010-04-30 | 2015-12-01 | Molecular Partners Ag | Modified binding proteins inhibiting the vegf-a receptor interaction |
| KR20140032356A (en) | 2010-11-26 | 2014-03-14 | 몰리큘라 파트너스 아게 | Improved n-terminal capping modules for designed ankyrin repeat protein |
| HUE046134T2 (en) | 2012-05-07 | 2020-02-28 | Allergan Inc | Method of treating amd in patients refractory to anti-vegf therapy |
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| WO2016005969A1 (en) | 2014-07-07 | 2016-01-14 | Yeda Research And Development Co. Ltd. | Method of computational protein design |
| US20170226158A1 (en) * | 2014-08-11 | 2017-08-10 | Medimmune Limited | Intracellular antigen binding |
| CN107148429B (en) | 2014-11-10 | 2021-12-03 | 豪夫迈·罗氏有限公司 | anti-PDGF-B antibodies and methods of use |
| EP3218399A1 (en) | 2014-11-10 | 2017-09-20 | F. Hoffmann-La Roche AG | Bispecific antibodies and methods of use in ophthalmology |
| KR20170082594A (en) | 2014-11-10 | 2017-07-14 | 에프. 호프만-라 로슈 아게 | Anti-ang2 antibodies and methods of use |
| BR112017009817A2 (en) | 2014-11-10 | 2018-02-14 | Hoffmann La Roche | anti-il-1beta antibodies and methods of use |
| EP4272838A3 (en) | 2015-04-02 | 2024-01-10 | Molecular Partners AG | Designed ankyrin repeat domains with binding specificity for serum albumin |
| US10283384B2 (en) * | 2015-04-27 | 2019-05-07 | Taiwan Semiconductor Manufacturing Co., Ltd. | Method for etching etch layer and wafer etching apparatus |
| WO2018054971A1 (en) | 2016-09-22 | 2018-03-29 | Molecular Partners Ag | Recombinant binding proteins and their use |
| US10037890B2 (en) * | 2016-10-11 | 2018-07-31 | Lam Research Corporation | Method for selectively etching with reduced aspect ratio dependence |
| US11127483B2 (en) | 2017-03-07 | 2021-09-21 | Igc Bio, Inc. | Computational pipeline for antibody modeling and design |
| US11655293B2 (en) | 2018-02-22 | 2023-05-23 | Universitat Zurich | Ligands to GM-CSF or GM-CSF-receptor for use in leukemia in a patient having undergone allo-HCT |
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| EP3768833A1 (en) | 2018-03-22 | 2021-01-27 | Charité - Universitätsmedizin Berlin | Crispr associated protein reactive t cell immunity |
| WO2019238966A1 (en) | 2018-06-15 | 2019-12-19 | Universität Bern | LIGANDS TO LIGHT OR ITS RECEPTOR LTßR FOR USE IN HAEMATOLOGIC MALIGNANCIES |
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| US5094941A (en) * | 1987-12-31 | 1992-03-10 | Zymogenetics, Inc. | Monoclonal antibodies to PDGF |
| EP0436597B1 (en) | 1988-09-02 | 1997-04-02 | Protein Engineering Corporation | Generation and selection of recombinant varied binding proteins |
| US5270170A (en) | 1991-10-16 | 1993-12-14 | Affymax Technologies N.V. | Peptide library and screening method |
| US5348867A (en) | 1991-11-15 | 1994-09-20 | George Georgiou | Expression of proteins on bacterial surface |
| CA2196496A1 (en) | 1997-01-31 | 1998-07-31 | Stephen William Watson Michnick | Protein fragment complementation assay for the detection of protein-protein interactions |
| DE69834032T2 (en) | 1997-04-23 | 2006-12-07 | Universität Zürich | METHOD OF DETECTING NUCLEIC ACID MOLECULES COPYING FOR (POLY) PEPTIDES THAT INTERACT WITH TARGET MOLECULES |
| WO2000032823A1 (en) | 1998-12-02 | 2000-06-08 | Phylos, Inc. | Dna-protein fusions and uses thereof |
| EP2149604A1 (en) * | 2000-09-08 | 2010-02-03 | Universität Zürich | Collections of repeat proteins comprising repeat modules |
| WO2003025019A1 (en) * | 2001-09-20 | 2003-03-27 | Alexion Pharmaceuticals, Inc. | Anti-pdgf antibodies and methods for producing engineered antibodies |
| ES2388138T3 (en) * | 2003-08-27 | 2012-10-09 | Ophthotech Corporation | Combination therapy for the treatment of ocular neovascular disorders |
| CA2585435A1 (en) * | 2004-11-12 | 2006-05-18 | Bayer Schering Pharma Aktiengesellschaft | Recombinant newcastle disease virus |
| WO2006129828A2 (en) | 2005-05-31 | 2006-12-07 | Canon Kabushiki Kaisha | Target substance capturing molecule |
| JP5042218B2 (en) | 2005-07-08 | 2012-10-03 | ユニバーシティ・オブ・チューリッヒ | Phage display using translocation simultaneously with translation of the fusion polypeptide |
| EP2863222A1 (en) | 2006-03-06 | 2015-04-22 | Amunix Operating Inc. | Unstructured recombinant polymers and uses thereof |
| ES2422007T3 (en) | 2007-06-21 | 2013-09-06 | Univ Muenchen Tech | Biological active proteins that have increased stability in vivo and / or in vitro |
| ES2614284T3 (en) | 2007-11-30 | 2017-05-30 | Glaxo Group Limited | Antigen binding constructs |
| WO2009100990A1 (en) * | 2008-02-13 | 2009-08-20 | Dsm Ip Assets B.V. | Process for the production of a peptide |
| WO2009115919A2 (en) * | 2008-03-19 | 2009-09-24 | Institut Pasteur | Reagentless fluorescent biosensors comprising a designed ankyrin repeat protein module, rational design methods to create reagentless fluorescent biosensors and methods of their use |
| ES2836948T3 (en) * | 2008-11-03 | 2021-06-28 | Molecular Partners Ag | Binding proteins that inhibit VEGF-A receptor interaction |
| TW201120210A (en) * | 2009-11-05 | 2011-06-16 | Hoffmann La Roche | Glycosylated repeat-motif-molecule conjugates |
| TWI510246B (en) | 2010-04-30 | 2015-12-01 | Molecular Partners Ag | Modified binding proteins inhibiting the vegf-a receptor interaction |
| KR20140032356A (en) * | 2010-11-26 | 2014-03-14 | 몰리큘라 파트너스 아게 | Improved n-terminal capping modules for designed ankyrin repeat protein |
| EA201391607A1 (en) * | 2011-04-29 | 2014-04-30 | Янссен Байотек, Инк. | BINDING IL4 / IL13 PROTEINS WITH REPEATERS AND THEIR APPLICATION |
-
2013
- 2013-06-27 CN CN201380034192.1A patent/CN104508129A/en active Pending
- 2013-06-27 EP EP13731809.3A patent/EP2867360B1/en active Active
- 2013-06-27 JP JP2015519089A patent/JP2015522576A/en active Pending
- 2013-06-27 BR BR112014032316A patent/BR112014032316A2/en not_active IP Right Cessation
- 2013-06-27 SG SG11201408196RA patent/SG11201408196RA/en unknown
- 2013-06-27 MX MX2014015825A patent/MX2014015825A/en unknown
- 2013-06-27 HK HK15109777.3A patent/HK1209156A1/en unknown
- 2013-06-27 CA CA2877584A patent/CA2877584A1/en not_active Abandoned
- 2013-06-27 WO PCT/EP2013/063488 patent/WO2014001442A1/en active Application Filing
- 2013-06-27 KR KR20157002327A patent/KR20150023957A/en not_active Withdrawn
- 2013-06-27 RU RU2014150224A patent/RU2014150224A/en not_active Application Discontinuation
- 2013-06-27 AU AU2013283296A patent/AU2013283296A1/en not_active Abandoned
- 2013-06-27 US US13/928,973 patent/US9163070B2/en active Active
-
2014
- 2014-12-03 ZA ZA2014/08872A patent/ZA201408872B/en unknown
- 2014-12-11 IN IN2522MUN2014 patent/IN2014MN02522A/en unknown
- 2014-12-24 IL IL236428A patent/IL236428A0/en unknown
-
2015
- 2015-09-08 US US14/847,403 patent/US20150368302A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2877584A1 (en) | 2014-01-03 |
| US9163070B2 (en) | 2015-10-20 |
| WO2014001442A1 (en) | 2014-01-03 |
| MX2014015825A (en) | 2015-08-10 |
| CN104508129A (en) | 2015-04-08 |
| RU2014150224A (en) | 2016-08-20 |
| IL236428A0 (en) | 2015-02-26 |
| EP2867360B1 (en) | 2019-05-08 |
| ZA201408872B (en) | 2016-05-25 |
| KR20150023957A (en) | 2015-03-05 |
| JP2015522576A (en) | 2015-08-06 |
| AU2013283296A1 (en) | 2015-02-05 |
| HK1209156A1 (en) | 2016-03-24 |
| US20140005125A1 (en) | 2014-01-02 |
| IN2014MN02522A (en) | 2015-07-17 |
| US20150368302A1 (en) | 2015-12-24 |
| EP2867360A1 (en) | 2015-05-06 |
| BR112014032316A2 (en) | 2017-06-27 |
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