MXPA06003615A - Ligandos del receptor vanilloide y su uso en tratamientos. - Google Patents
Ligandos del receptor vanilloide y su uso en tratamientos.Info
- Publication number
- MXPA06003615A MXPA06003615A MXPA06003615A MXPA06003615A MXPA06003615A MX PA06003615 A MXPA06003615 A MX PA06003615A MX PA06003615 A MXPA06003615 A MX PA06003615A MX PA06003615 A MXPA06003615 A MX PA06003615A MX PA06003615 A MXPA06003615 A MX PA06003615A
- Authority
- MX
- Mexico
- Prior art keywords
- ring
- substituted
- atoms
- groups
- unsaturated
- Prior art date
Links
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Manufacturing & Machinery (AREA)
- Ceramic Engineering (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Materials Engineering (AREA)
- Biomedical Technology (AREA)
- Structural Engineering (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50786303P | 2003-09-30 | 2003-09-30 | |
| PCT/US2004/032132 WO2005033105A2 (en) | 2003-09-30 | 2004-09-30 | Vanilloid receptor ligands and their use in treatments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA06003615A true MXPA06003615A (es) | 2006-06-05 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA06003615A MXPA06003615A (es) | 2003-09-30 | 2004-09-30 | Ligandos del receptor vanilloide y su uso en tratamientos. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7390907B2 (enExample) |
| EP (1) | EP1670794A2 (enExample) |
| JP (1) | JP2007533635A (enExample) |
| AU (1) | AU2004278382B2 (enExample) |
| CA (1) | CA2540640A1 (enExample) |
| MX (1) | MXPA06003615A (enExample) |
| WO (1) | WO2005033105A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2568451A1 (en) * | 2004-06-04 | 2005-12-22 | Arena Pharmaceuticals, Inc. | Substituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto |
| EP1805142A4 (en) | 2004-09-23 | 2009-06-10 | Reddy Us Therapeutics Inc | PYRIDINE-BASED COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING SAME |
| KR20080077652A (ko) * | 2005-12-22 | 2008-08-25 | 알콘 리서치, 리미티드 | 로 키나제-매개 질환 및 증상 치료용 (인다졸-5-일)피라진및 (1,3-디하이드로인돌-2-온)피라진 |
| PE20080145A1 (es) | 2006-03-21 | 2008-02-11 | Janssen Pharmaceutica Nv | Tetrahidro-pirimidoazepinas como moduladores de trpv1 |
| EP2044086A2 (en) * | 2006-06-30 | 2009-04-08 | Janssen Pharmaceutica N.V. | Thiazolopyrimidine modulators of trpv1 |
| BRPI0813244B8 (pt) | 2007-06-27 | 2021-05-25 | Astrazeneca Ab | compostos derivados de pirazinona, composições compreendendo ditos compostos, uso dos compostos no tratamento de doenças de pulmão e composto intermediário |
| WO2009078999A1 (en) | 2007-12-17 | 2009-06-25 | Janssen Pharmaceutica N.V. | Imidazolo-, oxazolo-, and thiazolopyrimidine modulators of trpv1 |
| CA2713553A1 (en) * | 2008-02-01 | 2009-08-06 | Akinion Pharmaceuticals Ab | Pyrazine derivatives and their use as protein kinase inhibitors |
| US11969501B2 (en) | 2008-04-21 | 2024-04-30 | Dompé Farmaceutici S.P.A. | Auris formulations for treating otic diseases and conditions |
| BRPI0910850B1 (pt) | 2008-04-21 | 2022-06-14 | Otonomy, Inc. | Composição intratimpânica compreendendo fator neurotrófico de crescimento derivado do cérebro (bdnf) para o tratamento ou prevenção da perda auditiva |
| WO2010011605A2 (en) | 2008-07-21 | 2010-01-28 | Otonomy, Inc. | Controlled-release otic structure modulating and innate immune system modulating compositions and methods for the treatment of otic disorders |
| EA201100427A1 (ru) * | 2008-09-02 | 2011-10-31 | Новартис Аг | Гетероциклические ингибиторы киназы |
| GB2463788B (en) * | 2008-09-29 | 2010-12-15 | Amira Pharmaceuticals Inc | Heteroaryl antagonists of prostaglandin D2 receptors |
| CN103298792A (zh) | 2010-11-19 | 2013-09-11 | 利亘制药公司 | 杂环胺及其用途 |
| EP3087059B1 (en) * | 2013-12-23 | 2020-04-29 | Purdue Pharma L.P. | Indazoles and use thereof |
| WO2015103355A1 (en) | 2014-01-01 | 2015-07-09 | Medivation Technologies, Inc. | Compounds and methods of use |
| US10807983B2 (en) | 2015-03-16 | 2020-10-20 | Ligand Pharmaceuticals, Inc. | Imidazo-fused heterocycles and uses thereof |
| HUE057838T2 (hu) | 2016-06-07 | 2022-06-28 | Jacobio Pharmaceuticals Co Ltd | SHP2 inhibitorokként hasznos új heterociklusos származékok |
| CA3029281A1 (en) | 2016-06-29 | 2018-01-04 | Otonomy, Inc. | Triglyceride otic formulations and uses thereof |
| TWI664175B (zh) | 2017-03-23 | 2019-07-01 | 大陸商北京加科思新藥研發有限公司 | 用於作為shp2抑制劑之新穎雜環衍生物 |
| CN112839935A (zh) | 2018-09-26 | 2021-05-25 | 北京加科思新药研发有限公司 | 可用作shp2抑制剂的新型杂环衍生物 |
| FI4182308T3 (fi) * | 2020-07-15 | 2024-12-07 | Chiesi Farm Spa | Pyridatsinyyliaminojohdannaisia alk5-estäjinä |
| CN118201915A (zh) | 2021-09-21 | 2024-06-14 | 奇斯药制品公司 | 作为alk5抑制剂的哒嗪基氨基衍生物 |
| US20250100997A1 (en) | 2022-01-11 | 2025-03-27 | Chiesi Farmaceutici S.P.A. | Pyridazinyl amino derivatives as alk5 inhibitors |
| DE102022104759A1 (de) | 2022-02-28 | 2023-08-31 | SCi Kontor GmbH | Co-Kristall-Screening Verfahren, insbesondere zur Herstellung von Co-Kristallen |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US204386A (en) * | 1878-05-28 | Improvement in wrenches | ||
| US195201A (en) * | 1877-09-18 | Improvement in flumes for establishing permanent channels in rivers | ||
| US82780A (en) * | 1868-10-06 | Improvement in machine foe scouring sheet metal | ||
| US38969A (en) * | 1863-06-23 | Improvement in harvesters | ||
| IL118469A (en) * | 1995-06-15 | 2000-08-13 | Tanabe Seiyaku Co | Naphthalene derivatives their preparation and intermediates thereof |
| JPH10251255A (ja) | 1997-03-14 | 1998-09-22 | Nissan Chem Ind Ltd | アジン誘導体 |
| DE69919361T2 (de) * | 1998-08-25 | 2005-09-08 | Ortho-Mcneil Pharmaceutical, Inc. | Pyridyl-ether und -thioether als nikotin-acetylcholin-rezeptorliganden und ihre therapeutische anwendung |
| EP1212319A2 (en) * | 1999-09-14 | 2002-06-12 | Abbott Laboratories | 3-pyrrolidinyloxy-3'-pyridyl ether compounds useful for controlling chemical synaptic transmission |
| JP2003534344A (ja) * | 2000-05-25 | 2003-11-18 | ターガセプト,インコーポレイテッド | ニコチン性コリン受容体リガンドとしてのヘテロアリールジアザビシクロアルカン |
| US6710048B2 (en) * | 2000-09-20 | 2004-03-23 | Ortho-Mcneil Pharmaceutical, Inc. | Pyrazine derivatives as modulators of tyrosine kinases |
| JP4272338B2 (ja) * | 2000-09-22 | 2009-06-03 | バイエル アクチェンゲゼルシャフト | ピリジン誘導体 |
| EP1506962B1 (en) * | 2000-10-20 | 2008-07-02 | Eisai R&D Management Co., Ltd. | Nitrogen-containing aromatic heterocycles |
| NZ525700A (en) | 2000-11-20 | 2004-12-24 | Biovitrum Ab | Piperazinylpyrazine compounds as agonist or antagonist of serotonin 5HT-2 receptor |
| WO2002060492A1 (en) | 2001-01-30 | 2002-08-08 | Cytopia Pty Ltd | Methods of inhibiting kinases |
| US6949544B2 (en) | 2001-03-29 | 2005-09-27 | Vertex Pharmaceuticals Incorporated | Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases |
| US6825198B2 (en) * | 2001-06-21 | 2004-11-30 | Pfizer Inc | 5-HT receptor ligands and uses thereof |
| MXPA04005427A (es) | 2001-12-10 | 2005-04-19 | Amgen Inc | Ligandos de receptor vainilloide y su uso en tratamientos. |
| PL375552A1 (en) | 2002-05-22 | 2005-11-28 | Amgen Inc. | Vanilloid receptor ligands and their medical applications |
| IL165264A0 (en) | 2002-05-23 | 2005-12-18 | Cytopia Pty Ltd | Protein kinase inhibitors |
| EP1511742B1 (en) * | 2002-05-23 | 2010-02-03 | Cytopia Research Pty Ltd | Kinase inhibitors |
| US7144888B2 (en) | 2002-08-08 | 2006-12-05 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
| US7419984B2 (en) | 2002-10-17 | 2008-09-02 | Cell Therapeutics, Inc. | Pyrimidines and uses thereof |
| US7342115B2 (en) | 2002-11-08 | 2008-03-11 | Neurogen Corporation | 3-substituted-6-aryl pyridines |
| GB0226724D0 (en) * | 2002-11-15 | 2002-12-24 | Merck Sharp & Dohme | Therapeutic agents |
| US7691905B2 (en) * | 2002-12-24 | 2010-04-06 | New York University | Inhibition of melanogenesis and melanoma metastasis with p-aminobenzoic acid (PABA) |
| JP2006516561A (ja) | 2003-01-17 | 2006-07-06 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | 細胞増殖の阻害剤としての2−アミノピリジン置換ヘテロ環類 |
| GB2400101A (en) | 2003-03-28 | 2004-10-06 | Biofocus Discovery Ltd | Compounds capable of binding to the active site of protein kinases |
| US20050014753A1 (en) | 2003-04-04 | 2005-01-20 | Irm Llc | Novel compounds and compositions as protein kinase inhibitors |
-
2004
- 2004-09-30 WO PCT/US2004/032132 patent/WO2005033105A2/en not_active Ceased
- 2004-09-30 CA CA002540640A patent/CA2540640A1/en not_active Abandoned
- 2004-09-30 EP EP04789334A patent/EP1670794A2/en not_active Withdrawn
- 2004-09-30 AU AU2004278382A patent/AU2004278382B2/en not_active Ceased
- 2004-09-30 MX MXPA06003615A patent/MXPA06003615A/es unknown
- 2004-09-30 JP JP2006534094A patent/JP2007533635A/ja active Pending
- 2004-09-30 US US10/956,648 patent/US7390907B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1670794A2 (en) | 2006-06-21 |
| CA2540640A1 (en) | 2005-04-14 |
| WO2005033105A2 (en) | 2005-04-14 |
| WO2005033105A3 (en) | 2005-06-23 |
| AU2004278382B2 (en) | 2008-09-18 |
| US7390907B2 (en) | 2008-06-24 |
| US20050153984A1 (en) | 2005-07-14 |
| JP2007533635A (ja) | 2007-11-22 |
| AU2004278382A1 (en) | 2005-04-14 |
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