MXPA05011521A - Derivado de 4,4-difluoro-1,2,3,4-tetrahidro-5h-1-benzazepina o una sal del mismo. - Google Patents
Derivado de 4,4-difluoro-1,2,3,4-tetrahidro-5h-1-benzazepina o una sal del mismo.Info
- Publication number
- MXPA05011521A MXPA05011521A MXPA05011521A MXPA05011521A MXPA05011521A MX PA05011521 A MXPA05011521 A MX PA05011521A MX PA05011521 A MXPA05011521 A MX PA05011521A MX PA05011521 A MXPA05011521 A MX PA05011521A MX PA05011521 A MXPA05011521 A MX PA05011521A
- Authority
- MX
- Mexico
- Prior art keywords
- difluoro
- tetrahydro
- salt
- benzazepine derivative
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Abstract
Un derivado de 4,4-difluoro-1,2,3,4-tetrahidro-5H-1-benzazepina novedoso representado por la siguiente formula (I) o una sal farmaceuticamente aceptable del derivado. Estas son utiles como un agente terapeutico o preventivo para la polaquisuria nocturna y/o la diabetes insipida.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003123032 | 2003-04-28 | ||
JP2003401126 | 2003-12-01 | ||
PCT/JP2004/005998 WO2004096775A1 (ja) | 2003-04-28 | 2004-04-26 | 4,4-ジフルオロ-1,2,3,4-テトラヒドロ-5h-1-ベンゾアゼピン誘導体又はその塩 |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA05011521A true MXPA05011521A (es) | 2006-01-23 |
Family
ID=33422056
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA05011521A MXPA05011521A (es) | 2003-04-28 | 2004-04-26 | Derivado de 4,4-difluoro-1,2,3,4-tetrahidro-5h-1-benzazepina o una sal del mismo. |
Country Status (17)
Country | Link |
---|---|
US (2) | US7183271B2 (es) |
EP (1) | EP1619185B1 (es) |
KR (1) | KR100882154B1 (es) |
AT (1) | ATE512951T1 (es) |
AU (1) | AU2004234258B2 (es) |
BR (1) | BRPI0409718A (es) |
CA (1) | CA2521492C (es) |
DK (1) | DK1619185T3 (es) |
IL (1) | IL171332A (es) |
MX (1) | MXPA05011521A (es) |
NO (1) | NO333505B1 (es) |
NZ (1) | NZ542815A (es) |
PL (1) | PL1619185T3 (es) |
PT (1) | PT1619185E (es) |
RU (1) | RU2326868C2 (es) |
SI (1) | SI1619185T1 (es) |
WO (1) | WO2004096775A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0210397D0 (en) * | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
SI1619185T1 (sl) | 2003-04-28 | 2011-09-30 | Astellas Pharma Inc | 4,4-difluoro-1,2,3,4-tetrahidro-5H-1-benzazepinski derivat ali njegova sol |
JP4754566B2 (ja) | 2005-07-22 | 2011-08-24 | 持田製薬株式会社 | 新規なヘテロシクリデンアセトアミド誘導体 |
US8399410B2 (en) | 2007-08-06 | 2013-03-19 | Allergan, Inc. | Methods and devices for desmopressin drug delivery |
US11963995B2 (en) | 2008-05-21 | 2024-04-23 | Ferring B.V. | Methods comprising desmopressin |
US20100286045A1 (en) | 2008-05-21 | 2010-11-11 | Bjarke Mirner Klein | Methods comprising desmopressin |
PT2712622T (pt) * | 2008-05-21 | 2016-10-13 | Ferring Bv | Desmopressina orodispersível para aumentar o período inicial de sono tranquilo |
PT2860175T (pt) | 2012-06-11 | 2018-02-02 | Tacurion | Método para a produção do composto 4,4,7-trifluoro--1,2,3,4-tetra-hidro-5h-1-benzazepina e intermediários para a sua síntese |
US10906888B2 (en) | 2016-07-14 | 2021-02-02 | Pfizer Inc. | Pyrimidine carboxamides as inhibitors of Vanin-1 enzyme |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ271454A (en) | 1993-08-26 | 1997-07-27 | Yamanouchi Pharma Co Ltd | Difluoro substituted benzazepine derivatives and pharmaceutical compositions |
JPH11349570A (ja) | 1994-06-15 | 1999-12-21 | Otsuka Pharmaceut Co Ltd | ベンゾヘテロ環誘導体 |
PT1221440E (pt) * | 1994-06-15 | 2007-07-20 | Otsuka Pharma Co Ltd | Derivados benzo-heterocíclicos úteis como moduladores da vasopressina ou oxitocina |
JP3215910B2 (ja) | 1994-06-15 | 2001-10-09 | 大塚製薬株式会社 | ベンゾヘテロ環誘導体 |
TW359669B (en) * | 1995-12-15 | 1999-06-01 | Otsuka Pharma Co Ltd | Benzazepine derivatives |
JPH09221476A (ja) | 1995-12-15 | 1997-08-26 | Otsuka Pharmaceut Co Ltd | 医薬組成物 |
JPH09221475A (ja) | 1996-02-13 | 1997-08-26 | Yamanouchi Pharmaceut Co Ltd | 新規なオキシム誘導体 |
AR011913A1 (es) | 1997-03-06 | 2000-09-13 | Yamano Masaki | Derivados de 4,4-difluoro-2,3,4,5-tetrahidro-1h-1-benzoazepina y composiciones farmaceuticas de los mismos. |
JP2926335B2 (ja) | 1997-06-13 | 1999-07-28 | 大塚製薬株式会社 | 医薬組成物 |
DE69826677T2 (de) | 1997-07-30 | 2005-02-10 | Wyeth | Trizyclische Vasopressin-Agonisten |
BR9811585A (pt) | 1997-07-30 | 2000-09-26 | American Home Prod | Agonistas de vasopressinas tricìclicas |
US6547395B1 (en) * | 1998-02-06 | 2003-04-15 | Wavefront Sciences, Inc. | Methods of measuring moving objects and reducing exposure during wavefront measurements |
EP1149096B1 (en) | 1999-02-04 | 2002-12-18 | Wyeth | Tricyclic pyridine n-oxides vasopressin agonists |
GB0000079D0 (en) * | 2000-01-05 | 2000-02-23 | Ferring Bv | Novel antidiuretic agents |
EP1445253B1 (en) * | 2001-11-16 | 2009-08-05 | Astellas Pharma Inc. | 4,4-difluoro-1, 2, 3, 4-tetrahydro-5h-1-benzazepine derivatives or salts thereof |
SI1619185T1 (sl) | 2003-04-28 | 2011-09-30 | Astellas Pharma Inc | 4,4-difluoro-1,2,3,4-tetrahidro-5H-1-benzazepinski derivat ali njegova sol |
-
2004
- 2004-04-26 SI SI200431724T patent/SI1619185T1/sl unknown
- 2004-04-26 EP EP04729502A patent/EP1619185B1/en not_active Expired - Lifetime
- 2004-04-26 US US10/554,150 patent/US7183271B2/en not_active Expired - Lifetime
- 2004-04-26 RU RU2005136863/04A patent/RU2326868C2/ru not_active IP Right Cessation
- 2004-04-26 CA CA2521492A patent/CA2521492C/en not_active Expired - Fee Related
- 2004-04-26 KR KR1020057020359A patent/KR100882154B1/ko active IP Right Grant
- 2004-04-26 AT AT04729502T patent/ATE512951T1/de active
- 2004-04-26 DK DK04729502.7T patent/DK1619185T3/da active
- 2004-04-26 BR BRPI0409718-1A patent/BRPI0409718A/pt not_active IP Right Cessation
- 2004-04-26 AU AU2004234258A patent/AU2004234258B2/en not_active Ceased
- 2004-04-26 WO PCT/JP2004/005998 patent/WO2004096775A1/ja not_active Application Discontinuation
- 2004-04-26 NZ NZ542815A patent/NZ542815A/en not_active IP Right Cessation
- 2004-04-26 PT PT04729502T patent/PT1619185E/pt unknown
- 2004-04-26 PL PL04729502T patent/PL1619185T3/pl unknown
- 2004-04-26 MX MXPA05011521A patent/MXPA05011521A/es active IP Right Grant
-
2005
- 2005-10-10 IL IL171332A patent/IL171332A/en active IP Right Grant
- 2005-11-25 NO NO20055602A patent/NO333505B1/no not_active IP Right Cessation
-
2006
- 2006-11-14 US US11/598,732 patent/US7807664B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CA2521492A1 (en) | 2004-11-11 |
SI1619185T1 (sl) | 2011-09-30 |
US7183271B2 (en) | 2007-02-27 |
EP1619185B1 (en) | 2011-06-15 |
NO20055602L (no) | 2006-01-24 |
PT1619185E (pt) | 2011-08-25 |
ATE512951T1 (de) | 2011-07-15 |
US7807664B2 (en) | 2010-10-05 |
RU2326868C2 (ru) | 2008-06-20 |
DK1619185T3 (da) | 2011-07-18 |
AU2004234258A1 (en) | 2004-11-11 |
AU2004234258B2 (en) | 2009-04-09 |
US20070167429A1 (en) | 2007-07-19 |
EP1619185A4 (en) | 2008-07-23 |
EP1619185A1 (en) | 2006-01-25 |
CA2521492C (en) | 2010-09-21 |
BRPI0409718A (pt) | 2006-05-02 |
WO2004096775A1 (ja) | 2004-11-11 |
IL171332A (en) | 2011-03-31 |
KR100882154B1 (ko) | 2009-02-06 |
NO20055602D0 (no) | 2005-11-25 |
NZ542815A (en) | 2009-01-31 |
NO333505B1 (no) | 2013-06-24 |
US20060122170A1 (en) | 2006-06-08 |
RU2005136863A (ru) | 2006-04-20 |
KR20060007402A (ko) | 2006-01-24 |
PL1619185T3 (pl) | 2011-12-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |