MXPA05006326A - Derivados diversamente sustituidos de guanidina, y su uso como medicamentos con actividad anti-diabetes y/o anti-obesidad. - Google Patents
Derivados diversamente sustituidos de guanidina, y su uso como medicamentos con actividad anti-diabetes y/o anti-obesidad.Info
- Publication number
- MXPA05006326A MXPA05006326A MXPA05006326A MXPA05006326A MXPA05006326A MX PA05006326 A MXPA05006326 A MX PA05006326A MX PA05006326 A MXPA05006326 A MX PA05006326A MX PA05006326 A MXPA05006326 A MX PA05006326A MX PA05006326 A MXPA05006326 A MX PA05006326A
- Authority
- MX
- Mexico
- Prior art keywords
- diabetes
- medicines
- guanidine
- substituted derivatives
- variously substituted
- Prior art date
Links
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 3
- 230000003579 anti-obesity Effects 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 150000002357 guanidines Chemical class 0.000 title 1
- 238000011282 treatment Methods 0.000 abstract 2
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 2
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 206010022489 Insulin Resistance Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 239000000883 anti-obesity agent Substances 0.000 abstract 1
- 229940125710 antiobesity agent Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000010030 glucose lowering effect Effects 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000625A ITRM20020625A1 (it) | 2002-12-17 | 2002-12-17 | Derivati di guanidine variamente sostituite, loro uso come medicamenti ad attivita' antidiabetica e/o antiobesita'. |
| PCT/IT2003/000792 WO2004054967A1 (en) | 2002-12-17 | 2003-12-01 | Variously substituted derivatives of guanidine, and their use as medicines with anti-diabetes and/or anti-obesity activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA05006326A true MXPA05006326A (es) | 2005-08-26 |
Family
ID=32587901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA05006326A MXPA05006326A (es) | 2002-12-17 | 2003-12-01 | Derivados diversamente sustituidos de guanidina, y su uso como medicamentos con actividad anti-diabetes y/o anti-obesidad. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7368605B2 (enExample) |
| EP (1) | EP1575912A1 (enExample) |
| JP (1) | JP2006509816A (enExample) |
| KR (1) | KR20050089058A (enExample) |
| CN (1) | CN1729172A (enExample) |
| AU (1) | AU2003288534B2 (enExample) |
| BR (1) | BR0317397A (enExample) |
| CA (1) | CA2506685A1 (enExample) |
| IT (1) | ITRM20020625A1 (enExample) |
| MX (1) | MXPA05006326A (enExample) |
| PL (1) | PL378416A1 (enExample) |
| WO (1) | WO2004054967A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2873368B1 (fr) * | 2004-07-26 | 2008-01-04 | Merck Sante Soc Par Actions Si | Derives de guanidine et leurs utilisations en therapeutique |
| CN101062906B (zh) * | 2006-04-26 | 2012-02-08 | 中国人民解放军军事医学科学院毒物药物研究所 | 胍丁胺硫酸盐水合物及其用于戒毒,抗炎,降血糖以及胍丁胺代谢异常所致疾病的用途 |
| CN101121677B (zh) * | 2006-08-09 | 2011-05-11 | 中国人民解放军军事医学科学院毒物药物研究所 | 胍丁胺硫酸盐二水合物及其医药用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU190639B (en) * | 1983-12-12 | 1986-09-29 | Gyogyszerkutato Intezet Kv,Hu | Process for production of new aminoguanidin derivatives |
| IT1219846B (it) * | 1988-02-24 | 1990-05-24 | Consiglio Nazionale Ricerche | Nuovi derivati guandinici ad attivita' ipotensia,composizione che li contengono e relativo procedimento di estrazione e purificazione da materiale botanico |
| EP0600973A1 (en) * | 1991-08-27 | 1994-06-15 | The Upjohn Company | A method for treatment of metabolic disorders and metabolism |
| GB9511757D0 (en) * | 1995-05-19 | 1995-08-02 | Univ Strathclyde | Agents for reducing weight |
| PL327471A1 (en) * | 1995-12-22 | 1998-12-07 | Smithkline Beecham Plc | Aminoguanidines for trweating niddm |
-
2002
- 2002-12-17 IT IT000625A patent/ITRM20020625A1/it unknown
-
2003
- 2003-12-01 EP EP03780657A patent/EP1575912A1/en not_active Withdrawn
- 2003-12-01 PL PL378416A patent/PL378416A1/pl not_active Application Discontinuation
- 2003-12-01 CA CA002506685A patent/CA2506685A1/en not_active Abandoned
- 2003-12-01 CN CNA2003801067329A patent/CN1729172A/zh active Pending
- 2003-12-01 JP JP2004560183A patent/JP2006509816A/ja active Pending
- 2003-12-01 BR BR0317397-6A patent/BR0317397A/pt not_active IP Right Cessation
- 2003-12-01 MX MXPA05006326A patent/MXPA05006326A/es not_active Application Discontinuation
- 2003-12-01 WO PCT/IT2003/000792 patent/WO2004054967A1/en not_active Ceased
- 2003-12-01 US US10/537,269 patent/US7368605B2/en not_active Expired - Fee Related
- 2003-12-01 AU AU2003288534A patent/AU2003288534B2/en not_active Ceased
- 2003-12-01 KR KR1020057011435A patent/KR20050089058A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006509816A (ja) | 2006-03-23 |
| KR20050089058A (ko) | 2005-09-07 |
| CA2506685A1 (en) | 2004-07-01 |
| AU2003288534A1 (en) | 2004-07-09 |
| EP1575912A1 (en) | 2005-09-21 |
| AU2003288534B2 (en) | 2009-07-02 |
| US20060069100A1 (en) | 2006-03-30 |
| PL378416A1 (pl) | 2006-04-03 |
| WO2004054967A1 (en) | 2004-07-01 |
| CN1729172A (zh) | 2006-02-01 |
| US7368605B2 (en) | 2008-05-06 |
| BR0317397A (pt) | 2005-11-16 |
| ITRM20020625A1 (it) | 2004-06-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |