BR0317397A - Derivados de guanidina variadamente substituìdos e seu uso como medicamentos com atividade antidiabetes e/ou antiobesidade - Google Patents
Derivados de guanidina variadamente substituìdos e seu uso como medicamentos com atividade antidiabetes e/ou antiobesidadeInfo
- Publication number
- BR0317397A BR0317397A BR0317397-6A BR0317397A BR0317397A BR 0317397 A BR0317397 A BR 0317397A BR 0317397 A BR0317397 A BR 0317397A BR 0317397 A BR0317397 A BR 0317397A
- Authority
- BR
- Brazil
- Prior art keywords
- diabetes
- guanidine derivatives
- substituted guanidine
- obesity
- obesity drugs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000625A ITRM20020625A1 (it) | 2002-12-17 | 2002-12-17 | Derivati di guanidine variamente sostituite, loro uso come medicamenti ad attivita' antidiabetica e/o antiobesita'. |
| PCT/IT2003/000792 WO2004054967A1 (en) | 2002-12-17 | 2003-12-01 | Variously substituted derivatives of guanidine, and their use as medicines with anti-diabetes and/or anti-obesity activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0317397A true BR0317397A (pt) | 2005-11-16 |
Family
ID=32587901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0317397-6A BR0317397A (pt) | 2002-12-17 | 2003-12-01 | Derivados de guanidina variadamente substituìdos e seu uso como medicamentos com atividade antidiabetes e/ou antiobesidade |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7368605B2 (enExample) |
| EP (1) | EP1575912A1 (enExample) |
| JP (1) | JP2006509816A (enExample) |
| KR (1) | KR20050089058A (enExample) |
| CN (1) | CN1729172A (enExample) |
| AU (1) | AU2003288534B2 (enExample) |
| BR (1) | BR0317397A (enExample) |
| CA (1) | CA2506685A1 (enExample) |
| IT (1) | ITRM20020625A1 (enExample) |
| MX (1) | MXPA05006326A (enExample) |
| PL (1) | PL378416A1 (enExample) |
| WO (1) | WO2004054967A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2873368B1 (fr) * | 2004-07-26 | 2008-01-04 | Merck Sante Soc Par Actions Si | Derives de guanidine et leurs utilisations en therapeutique |
| CN101062906B (zh) * | 2006-04-26 | 2012-02-08 | 中国人民解放军军事医学科学院毒物药物研究所 | 胍丁胺硫酸盐水合物及其用于戒毒,抗炎,降血糖以及胍丁胺代谢异常所致疾病的用途 |
| CN101121677B (zh) * | 2006-08-09 | 2011-05-11 | 中国人民解放军军事医学科学院毒物药物研究所 | 胍丁胺硫酸盐二水合物及其医药用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU190639B (en) * | 1983-12-12 | 1986-09-29 | Gyogyszerkutato Intezet Kv,Hu | Process for production of new aminoguanidin derivatives |
| IT1219846B (it) * | 1988-02-24 | 1990-05-24 | Consiglio Nazionale Ricerche | Nuovi derivati guandinici ad attivita' ipotensia,composizione che li contengono e relativo procedimento di estrazione e purificazione da materiale botanico |
| EP0600973A1 (en) * | 1991-08-27 | 1994-06-15 | The Upjohn Company | A method for treatment of metabolic disorders and metabolism |
| GB9511757D0 (en) * | 1995-05-19 | 1995-08-02 | Univ Strathclyde | Agents for reducing weight |
| PL327471A1 (en) * | 1995-12-22 | 1998-12-07 | Smithkline Beecham Plc | Aminoguanidines for trweating niddm |
-
2002
- 2002-12-17 IT IT000625A patent/ITRM20020625A1/it unknown
-
2003
- 2003-12-01 EP EP03780657A patent/EP1575912A1/en not_active Withdrawn
- 2003-12-01 PL PL378416A patent/PL378416A1/pl not_active Application Discontinuation
- 2003-12-01 CA CA002506685A patent/CA2506685A1/en not_active Abandoned
- 2003-12-01 CN CNA2003801067329A patent/CN1729172A/zh active Pending
- 2003-12-01 JP JP2004560183A patent/JP2006509816A/ja active Pending
- 2003-12-01 BR BR0317397-6A patent/BR0317397A/pt not_active IP Right Cessation
- 2003-12-01 MX MXPA05006326A patent/MXPA05006326A/es not_active Application Discontinuation
- 2003-12-01 WO PCT/IT2003/000792 patent/WO2004054967A1/en not_active Ceased
- 2003-12-01 US US10/537,269 patent/US7368605B2/en not_active Expired - Fee Related
- 2003-12-01 AU AU2003288534A patent/AU2003288534B2/en not_active Ceased
- 2003-12-01 KR KR1020057011435A patent/KR20050089058A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006509816A (ja) | 2006-03-23 |
| KR20050089058A (ko) | 2005-09-07 |
| CA2506685A1 (en) | 2004-07-01 |
| AU2003288534A1 (en) | 2004-07-09 |
| EP1575912A1 (en) | 2005-09-21 |
| AU2003288534B2 (en) | 2009-07-02 |
| US20060069100A1 (en) | 2006-03-30 |
| PL378416A1 (pl) | 2006-04-03 |
| WO2004054967A1 (en) | 2004-07-01 |
| CN1729172A (zh) | 2006-02-01 |
| US7368605B2 (en) | 2008-05-06 |
| ITRM20020625A1 (it) | 2004-06-18 |
| MXPA05006326A (es) | 2005-08-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A E 8A ANUIDADE(S). |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012. |