ITRM20020625A1 - Derivati di guanidine variamente sostituite, loro uso come medicamenti ad attivita' antidiabetica e/o antiobesita'. - Google Patents
Derivati di guanidine variamente sostituite, loro uso come medicamenti ad attivita' antidiabetica e/o antiobesita'.Info
- Publication number
- ITRM20020625A1 ITRM20020625A1 IT000625A ITRM20020625A ITRM20020625A1 IT RM20020625 A1 ITRM20020625 A1 IT RM20020625A1 IT 000625 A IT000625 A IT 000625A IT RM20020625 A ITRM20020625 A IT RM20020625A IT RM20020625 A1 ITRM20020625 A1 IT RM20020625A1
- Authority
- IT
- Italy
- Prior art keywords
- medications
- guanidine
- diabetic
- derivatives
- variously replaced
- Prior art date
Links
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical class NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 title 1
- 230000003178 anti-diabetic effect Effects 0.000 title 1
- 230000003579 anti-obesity Effects 0.000 title 1
- 239000003472 antidiabetic agent Substances 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000625A ITRM20020625A1 (it) | 2002-12-17 | 2002-12-17 | Derivati di guanidine variamente sostituite, loro uso come medicamenti ad attivita' antidiabetica e/o antiobesita'. |
| CA002506685A CA2506685A1 (en) | 2002-12-17 | 2003-12-01 | Variously substituted derivatives of guanidine, and their use as medicines with anti-diabetes and/or anti-obesity activity |
| KR1020057011435A KR20050089058A (ko) | 2002-12-17 | 2003-12-01 | 구아니딘의 다양하게 치환된 유도체, 및 당뇨병 치료및/또는 비만 억제 활성을 갖는 약제로서의 그의 용도 |
| AU2003288534A AU2003288534B2 (en) | 2002-12-17 | 2003-12-01 | Variously substituted derivatives of guanidine, and their use as medicines with anti-diabetes and/or anti-obesity activity |
| EP03780657A EP1575912A1 (en) | 2002-12-17 | 2003-12-01 | Variously substituted derivatives of guanidine, and their use as medicines with anti-diabetes and/or anti-obesity activity |
| JP2004560183A JP2006509816A (ja) | 2002-12-17 | 2003-12-01 | 抗糖尿病性および／または肥満抑制性作用を有する、グアニジンの種々の置換誘導体、および医薬としてのその使用 |
| MXPA05006326A MXPA05006326A (es) | 2002-12-17 | 2003-12-01 | Derivados diversamente sustituidos de guanidina, y su uso como medicamentos con actividad anti-diabetes y/o anti-obesidad. |
| PCT/IT2003/000792 WO2004054967A1 (en) | 2002-12-17 | 2003-12-01 | Variously substituted derivatives of guanidine, and their use as medicines with anti-diabetes and/or anti-obesity activity |
| BR0317397-6A BR0317397A (pt) | 2002-12-17 | 2003-12-01 | Derivados de guanidina variadamente substituìdos e seu uso como medicamentos com atividade antidiabetes e/ou antiobesidade |
| US10/537,269 US7368605B2 (en) | 2002-12-17 | 2003-12-01 | Variously substituted derivatives of guanidine, and their use as medicines with anti-diabetes and/or anti-obesity activity |
| CNA2003801067329A CN1729172A (zh) | 2002-12-17 | 2003-12-01 | 胍的不同取代的衍生物及其作为具有抗糖尿病和/或抗肥胖活性的药物的用途 |
| PL378416A PL378416A1 (pl) | 2002-12-17 | 2003-12-01 | Różnie podstawione pochodne guanidyny i ich zastosowanie jako leki o aktywności przeciwcukrzycowej i/lub przeciw otyłości |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000625A ITRM20020625A1 (it) | 2002-12-17 | 2002-12-17 | Derivati di guanidine variamente sostituite, loro uso come medicamenti ad attivita' antidiabetica e/o antiobesita'. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ITRM20020625A1 true ITRM20020625A1 (it) | 2004-06-18 |
Family
ID=32587901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT000625A ITRM20020625A1 (it) | 2002-12-17 | 2002-12-17 | Derivati di guanidine variamente sostituite, loro uso come medicamenti ad attivita' antidiabetica e/o antiobesita'. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7368605B2 (enExample) |
| EP (1) | EP1575912A1 (enExample) |
| JP (1) | JP2006509816A (enExample) |
| KR (1) | KR20050089058A (enExample) |
| CN (1) | CN1729172A (enExample) |
| AU (1) | AU2003288534B2 (enExample) |
| BR (1) | BR0317397A (enExample) |
| CA (1) | CA2506685A1 (enExample) |
| IT (1) | ITRM20020625A1 (enExample) |
| MX (1) | MXPA05006326A (enExample) |
| PL (1) | PL378416A1 (enExample) |
| WO (1) | WO2004054967A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2873368B1 (fr) * | 2004-07-26 | 2008-01-04 | Merck Sante Soc Par Actions Si | Derives de guanidine et leurs utilisations en therapeutique |
| CN101062906B (zh) * | 2006-04-26 | 2012-02-08 | 中国人民解放军军事医学科学院毒物药物研究所 | 胍丁胺硫酸盐水合物及其用于戒毒,抗炎,降血糖以及胍丁胺代谢异常所致疾病的用途 |
| CN101121677B (zh) * | 2006-08-09 | 2011-05-11 | 中国人民解放军军事医学科学院毒物药物研究所 | 胍丁胺硫酸盐二水合物及其医药用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU190639B (en) * | 1983-12-12 | 1986-09-29 | Gyogyszerkutato Intezet Kv,Hu | Process for production of new aminoguanidin derivatives |
| IT1219846B (it) * | 1988-02-24 | 1990-05-24 | Consiglio Nazionale Ricerche | Nuovi derivati guandinici ad attivita' ipotensia,composizione che li contengono e relativo procedimento di estrazione e purificazione da materiale botanico |
| EP0600973A1 (en) * | 1991-08-27 | 1994-06-15 | The Upjohn Company | A method for treatment of metabolic disorders and metabolism |
| GB9511757D0 (en) * | 1995-05-19 | 1995-08-02 | Univ Strathclyde | Agents for reducing weight |
| PL327471A1 (en) * | 1995-12-22 | 1998-12-07 | Smithkline Beecham Plc | Aminoguanidines for trweating niddm |
-
2002
- 2002-12-17 IT IT000625A patent/ITRM20020625A1/it unknown
-
2003
- 2003-12-01 EP EP03780657A patent/EP1575912A1/en not_active Withdrawn
- 2003-12-01 PL PL378416A patent/PL378416A1/pl not_active Application Discontinuation
- 2003-12-01 CA CA002506685A patent/CA2506685A1/en not_active Abandoned
- 2003-12-01 CN CNA2003801067329A patent/CN1729172A/zh active Pending
- 2003-12-01 JP JP2004560183A patent/JP2006509816A/ja active Pending
- 2003-12-01 BR BR0317397-6A patent/BR0317397A/pt not_active IP Right Cessation
- 2003-12-01 MX MXPA05006326A patent/MXPA05006326A/es not_active Application Discontinuation
- 2003-12-01 WO PCT/IT2003/000792 patent/WO2004054967A1/en not_active Ceased
- 2003-12-01 US US10/537,269 patent/US7368605B2/en not_active Expired - Fee Related
- 2003-12-01 AU AU2003288534A patent/AU2003288534B2/en not_active Ceased
- 2003-12-01 KR KR1020057011435A patent/KR20050089058A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006509816A (ja) | 2006-03-23 |
| KR20050089058A (ko) | 2005-09-07 |
| CA2506685A1 (en) | 2004-07-01 |
| AU2003288534A1 (en) | 2004-07-09 |
| EP1575912A1 (en) | 2005-09-21 |
| AU2003288534B2 (en) | 2009-07-02 |
| US20060069100A1 (en) | 2006-03-30 |
| PL378416A1 (pl) | 2006-04-03 |
| WO2004054967A1 (en) | 2004-07-01 |
| CN1729172A (zh) | 2006-02-01 |
| US7368605B2 (en) | 2008-05-06 |
| BR0317397A (pt) | 2005-11-16 |
| MXPA05006326A (es) | 2005-08-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ITRM20010464A0 (it) | Derivati retinoidi ad attivita' antiangiogenica, antitumorale e pro-apoptotica. | |
| DE50312295D1 (de) | 8-ä3-amino-piperidin-1-ylü -xanthine, deren herstellung und deren verwendung als arzneimittel | |
| DE50209483D1 (de) | Xanthinderivate, deren herstellung und deren verwendung als arzneimittel | |
| ITRM20020411A1 (it) | Derivati dello spirobifluorene, loro preparazione e loro uso. | |
| DE50312747D1 (de) | Neue xanthinderivate, deren herstellung und deren verwendung als arzneimittel | |
| EE200300311A (et) | Ftalasinoon-piperidinoderivaadid, nende kasutamine ja ravim | |
| DE50313653D1 (de) | Wasserlösliche eisen-kohlenhydrat-komplexe, deren herstellung und diese enthaltende arzneimittel | |
| PT1500654E (pt) | Derivados de benzoxazinona, sua preparacao e utilizacao como medicamentos | |
| DE60235547D1 (de) | En daraus, deren herstellung und verwendung | |
| ITRM20020016A1 (it) | Derivati di acidi fenil(alchil)carbossilici e derivati fenilalchileterociclici dionici, loro uso come medicamenti ad attivita' ipoglicemizza | |
| WO2004043362A3 (en) | Acyl guanidine compounds and use thereof | |
| ITRM20030363A0 (it) | Composizioni comprendenti la 3, 5diiodotironina e uso farmaceutico diesse. | |
| DE50206476D1 (de) | Cyanoanthranylamid-derivate und deren verwendung als arzneimittel | |
| DE60321372D1 (de) | 3-phenylpyridoindolderivate, ihre herstellung und verwendung | |
| RU2002107079A (ru) | Вещество, обладающее седативным действием | |
| ITRM20020629A1 (it) | Uso di acidi alfa-feniltiocarbossilici e alfa-fenilossicarbossilici ad attivita' ipoglicemizzante e/o ipolipidemizzante. | |
| ATE484503T1 (de) | 2-pyrrolidin-2-yl-ä1,3,4ü -oxadiazol-derivate und ihre verwendung als antidepressiva | |
| ITRM20020402A0 (it) | Derivati fluoro-alchil-ciclopeptidi ad attivita' anti-integrine. | |
| NO20014692D0 (no) | 3-amidinobenzensulfonamidderivater, medisinske sammensetninger inneholdende slike samt intermediater vedfremstillingen derav | |
| ITRM20020119A1 (it) | Composizioni contenenti plgf ad uso farmaceutico e cosmetico. | |
| ITMI20020872A0 (it) | Derivati dell'iperforina loro uso e formulazioni che li contengono | |
| DE50211897D1 (de) | 3H-NAPHTHOÄ2,1-bÜ-PYRAN-DERIVATE SOWIE DEREN VERWENDUNG | |
| PL372089A1 (en) | Substituted propane-1,3-diamine derivatives and the pharmaceutical use thereof | |
| RU2001109481A (ru) | Антиангинальное средство | |
| PL378416A1 (pl) | Różnie podstawione pochodne guanidyny i ich zastosowanie jako leki o aktywności przeciwcukrzycowej i/lub przeciw otyłości |