ATE449066T1 - Biguanidderivate - Google Patents
BiguanidderivateInfo
- Publication number
- ATE449066T1 ATE449066T1 AT02753575T AT02753575T ATE449066T1 AT E449066 T1 ATE449066 T1 AT E449066T1 AT 02753575 T AT02753575 T AT 02753575T AT 02753575 T AT02753575 T AT 02753575T AT E449066 T1 ATE449066 T1 AT E449066T1
- Authority
- AT
- Austria
- Prior art keywords
- biguanide derivatives
- biguanide
- derivatives
- hyperglycaemia
- diabetes
- Prior art date
Links
- XNCOSPRUTUOJCJ-UHFFFAOYSA-N Biguanide Chemical class NC(N)=NC(N)=N XNCOSPRUTUOJCJ-UHFFFAOYSA-N 0.000 title 1
- 150000004283 biguanides Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 201000001421 hyperglycemia Diseases 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
- Indole Compounds (AREA)
- Lubricants (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0103846A FR2822464B1 (fr) | 2001-03-21 | 2001-03-21 | Derives biguanides et leurs applications en therapeutique |
| PCT/EP2002/003119 WO2002074740A1 (en) | 2001-03-21 | 2002-03-20 | Biguanide derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE449066T1 true ATE449066T1 (de) | 2009-12-15 |
Family
ID=8861407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02753575T ATE449066T1 (de) | 2001-03-21 | 2002-03-20 | Biguanidderivate |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US7285681B2 (de) |
| EP (1) | EP1370525B1 (de) |
| JP (1) | JP4418157B2 (de) |
| KR (1) | KR20030085558A (de) |
| CN (1) | CN1228325C (de) |
| AT (1) | ATE449066T1 (de) |
| AU (1) | AU2002308178B2 (de) |
| BR (1) | BR0208131A (de) |
| CA (1) | CA2441309C (de) |
| CZ (1) | CZ20032766A3 (de) |
| DE (1) | DE60234424D1 (de) |
| ES (1) | ES2336771T3 (de) |
| FR (1) | FR2822464B1 (de) |
| HU (1) | HUP0303593A3 (de) |
| MX (1) | MXPA03008404A (de) |
| NO (1) | NO20034171L (de) |
| PL (1) | PL362528A1 (de) |
| RU (1) | RU2276136C2 (de) |
| SK (1) | SK12802003A3 (de) |
| WO (1) | WO2002074740A1 (de) |
| ZA (1) | ZA200308146B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101417988B (zh) * | 2007-10-24 | 2011-04-27 | 山东轩竹医药科技有限公司 | 双胍哌嗪类二肽酰肽酶ⅳ抑制剂 |
| KR101041428B1 (ko) * | 2008-10-13 | 2011-06-14 | 한국화학연구원 | Ｎ1-2-티오펜-2-일에틸-ｎ2-치환된 바이구아나이드 유도체,이의 제조방법 및 이를 유효성분으로 함유하는 약학 조성물 |
| WO2010103040A1 (en) | 2009-03-10 | 2010-09-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | 5'-adenosine monophosphate-activated protein kinase (ampk) activators for treating pulmonary hypertension |
| KR101136045B1 (ko) * | 2009-11-16 | 2012-04-18 | 한국화학연구원 | Ｎ1-(펜에틸)-ｎ2-치환된 바이구아나이드 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 약학 조성물 |
| NL1037643C2 (en) * | 2010-01-22 | 2011-07-25 | Karel Paul Bouter | Nutritional product comprising a biguanide. |
| KR101324283B1 (ko) * | 2010-04-27 | 2013-11-01 | 한올바이오파마주식회사 | 바이구아나이드 화합물의 신규 염, 그의 제조방법, 그를 포함하는 약제학적 조성물 |
| CA2913736A1 (en) * | 2012-06-11 | 2013-12-19 | The Regents Of The University Of California | Compounds and methods of treating cancer |
| KR102216701B1 (ko) | 2014-11-20 | 2021-02-18 | 이뮤노메트테라퓨틱스 인코포레이티드 | 바이구아나이드 화합물 및 이의 용도 |
| KR102364358B1 (ko) * | 2015-04-30 | 2022-02-17 | 이뮤노메트테라퓨틱스 인코포레이티드 | 구아니딘 화합물 및 이의 용도 |
| CN105125689B (zh) * | 2015-09-21 | 2018-01-19 | 株洲千金药业股份有限公司 | 一种含有妇科千金片药渣的足浴粉及其制备方法 |
| US10344002B2 (en) | 2016-09-26 | 2019-07-09 | Nusirt Sciences, Inc. | Compositions and methods for treating metabolic disorders |
| CN113354561B (zh) * | 2021-04-17 | 2023-03-28 | 中山大学 | 双胍衍生物及其应用与制剂 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB852584A (en) * | 1956-05-31 | 1960-10-26 | Us Vitamin Corp | Biguanide compositions |
| US2937173A (en) * | 1959-05-06 | 1960-05-17 | Us Vitamin Pharm Corp | Indolino and tetrahydroquinolino triazines |
| US3879541A (en) | 1970-03-03 | 1975-04-22 | Bayer Ag | Antihyperglycemic methods and compositions |
| DE2009743A1 (de) * | 1970-03-03 | 1971-09-16 | Farbenfabriken Bayer Ag, 5090 Leverkusen | Substituierte Biguanide mit antihyperglykämischer Wirkung |
| US3960949A (en) | 1971-04-02 | 1976-06-01 | Schering Aktiengesellschaft | 1,2-Biguanides |
| EP0034002A3 (de) | 1980-01-22 | 1981-09-23 | Beecham Group Plc | Carboxamidinderivate |
| JPS6141367A (ja) * | 1984-08-02 | 1986-02-27 | 三菱瓦斯化学株式会社 | 繊維または繊維製品の過酸化水素による漂白法 |
| FR2696740B1 (fr) * | 1992-10-13 | 1994-12-30 | Dospharma Sa | Dérivés prodrogués de la diméthylbiguanide et applications comme médicaments. |
-
2001
- 2001-03-21 FR FR0103846A patent/FR2822464B1/fr not_active Expired - Fee Related
-
2002
- 2002-03-20 BR BR0208131-8A patent/BR0208131A/pt not_active IP Right Cessation
- 2002-03-20 AU AU2002308178A patent/AU2002308178B2/en not_active Ceased
- 2002-03-20 KR KR10-2003-7012150A patent/KR20030085558A/ko not_active Ceased
- 2002-03-20 US US10/472,229 patent/US7285681B2/en not_active Expired - Fee Related
- 2002-03-20 JP JP2002573749A patent/JP4418157B2/ja not_active Expired - Fee Related
- 2002-03-20 AT AT02753575T patent/ATE449066T1/de not_active IP Right Cessation
- 2002-03-20 EP EP02753575A patent/EP1370525B1/de not_active Expired - Lifetime
- 2002-03-20 RU RU2003130070/04A patent/RU2276136C2/ru not_active IP Right Cessation
- 2002-03-20 WO PCT/EP2002/003119 patent/WO2002074740A1/en not_active Ceased
- 2002-03-20 HU HU0303593A patent/HUP0303593A3/hu unknown
- 2002-03-20 MX MXPA03008404A patent/MXPA03008404A/es not_active Application Discontinuation
- 2002-03-20 CN CNB02806254XA patent/CN1228325C/zh not_active Expired - Fee Related
- 2002-03-20 ES ES02753575T patent/ES2336771T3/es not_active Expired - Lifetime
- 2002-03-20 CZ CZ20032766A patent/CZ20032766A3/cs unknown
- 2002-03-20 CA CA2441309A patent/CA2441309C/en not_active Expired - Fee Related
- 2002-03-20 DE DE60234424T patent/DE60234424D1/de not_active Expired - Lifetime
- 2002-03-20 PL PL02362528A patent/PL362528A1/xx unknown
- 2002-03-20 SK SK1280-2003A patent/SK12802003A3/sk unknown
-
2003
- 2003-09-19 NO NO20034171A patent/NO20034171L/no not_active Application Discontinuation
- 2003-10-20 ZA ZA200308146A patent/ZA200308146B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK1062172A1 (en) | 2004-10-21 |
| NO20034171D0 (no) | 2003-09-19 |
| HUP0303593A3 (en) | 2007-03-28 |
| JP4418157B2 (ja) | 2010-02-17 |
| US7285681B2 (en) | 2007-10-23 |
| MXPA03008404A (es) | 2004-01-29 |
| PL362528A1 (en) | 2004-11-02 |
| EP1370525B1 (de) | 2009-11-18 |
| CZ20032766A3 (cs) | 2004-01-14 |
| RU2003130070A (ru) | 2005-04-10 |
| JP2004523580A (ja) | 2004-08-05 |
| KR20030085558A (ko) | 2003-11-05 |
| BR0208131A (pt) | 2004-03-02 |
| ZA200308146B (en) | 2005-01-20 |
| HUP0303593A2 (hu) | 2004-03-01 |
| WO2002074740A1 (en) | 2002-09-26 |
| CN1228325C (zh) | 2005-11-23 |
| CA2441309A1 (en) | 2002-09-26 |
| AU2002308178B2 (en) | 2007-03-01 |
| DE60234424D1 (en) | 2009-12-31 |
| CA2441309C (en) | 2010-06-15 |
| US20040092495A1 (en) | 2004-05-13 |
| FR2822464B1 (fr) | 2004-08-06 |
| CN1496347A (zh) | 2004-05-12 |
| RU2276136C2 (ru) | 2006-05-10 |
| EP1370525A1 (de) | 2003-12-17 |
| SK12802003A3 (sk) | 2004-02-03 |
| NO20034171L (no) | 2003-09-19 |
| ES2336771T3 (es) | 2010-04-16 |
| FR2822464A1 (fr) | 2002-09-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |