MXPA05005288A - Inmunoanalisis no competitivo para analitos pequenos. - Google Patents

Inmunoanalisis no competitivo para analitos pequenos.

Info

Publication number
MXPA05005288A
MXPA05005288A MXPA05005288A MXPA05005288A MXPA05005288A MX PA05005288 A MXPA05005288 A MX PA05005288A MX PA05005288 A MXPA05005288 A MX PA05005288A MX PA05005288 A MXPA05005288 A MX PA05005288A MX PA05005288 A MXPA05005288 A MX PA05005288A
Authority
MX
Mexico
Prior art keywords
analyte
binding partner
competitive immunoassay
binding
small analytes
Prior art date
Application number
MXPA05005288A
Other languages
English (en)
Inventor
Soderlund Hans
Original Assignee
Valtion Teknillinen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valtion Teknillinen filed Critical Valtion Teknillinen
Publication of MXPA05005288A publication Critical patent/MXPA05005288A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/6857—Antibody fragments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/946—CNS-stimulants, e.g. cocaine, amphetamines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/948—Sedatives, e.g. cannabinoids, barbiturates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9486—Analgesics, e.g. opiates, aspirine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
    • G01N2470/04—Sandwich assay format
    • G01N2470/06—Second binding partner specifically binding complex of analyte with first binding partner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Wrappers (AREA)

Abstract

La invencion esta dirigida a un inmunoanalisis no competitivo para analitos pequenos; donde se hace reaccionar el analito con dos participes de union. El primer participe de union se une al analito para formar un complejo entre el primer participe de union y el analito; y el segundo participe de union se une al complejo formado por el primer participe de union y el analito. Se detecta el complejo resultante, formado entre el analito y los participes de union. Los participes de union son proteinas, tales como anticuerpos que incluyen fragmentos de anticuerpo. La invencion se refiere adicionalmente a pares reactivos y equipos de prueba utiles en los analisis, asi como al uso de los pares reactivos y aun proceso para su preparacion. Tambien estan provistos reactivos novedosos y medios para su preparacion.
MXPA05005288A 2002-11-18 2003-11-17 Inmunoanalisis no competitivo para analitos pequenos. MXPA05005288A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20022048A FI20022048A0 (fi) 2002-11-18 2002-11-18 Ei-kompetetiivinen immunomääritys pienille analyyteille
PCT/FI2003/000875 WO2004046733A1 (en) 2002-11-18 2003-11-17 Non-competitive immunoassay for small analytes

Publications (1)

Publication Number Publication Date
MXPA05005288A true MXPA05005288A (es) 2005-08-16

Family

ID=8564953

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05005288A MXPA05005288A (es) 2002-11-18 2003-11-17 Inmunoanalisis no competitivo para analitos pequenos.

Country Status (17)

Country Link
US (1) US7749712B2 (es)
EP (1) EP1579222B8 (es)
JP (1) JP4729701B2 (es)
CN (1) CN1711476B (es)
AT (1) ATE408146T1 (es)
BR (1) BRPI0316384B8 (es)
CA (1) CA2503509C (es)
DE (1) DE60323538D1 (es)
DK (1) DK1579222T3 (es)
EA (1) EA200500643A1 (es)
ES (1) ES2312828T3 (es)
FI (1) FI20022048A0 (es)
MX (1) MXPA05005288A (es)
NO (1) NO338417B1 (es)
NZ (1) NZ539714A (es)
WO (1) WO2004046733A1 (es)
ZA (1) ZA200503475B (es)

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Publication number Priority date Publication date Assignee Title
US20030109067A1 (en) 2001-12-06 2003-06-12 Immunetech, Inc. Homogeneous immunoassays for multiple allergens
JP2007040834A (ja) * 2005-08-03 2007-02-15 Japan Science & Technology Agency 免疫測定用試薬
FI20075251A0 (fi) 2007-04-13 2007-04-13 Hytest Oy Immunomääritys epästabiilien antigeenien määrittämiseksi
GB0707870D0 (en) * 2007-04-23 2007-05-30 Selected Antibodies Ltd Assay Devices and Methods and Components for use Therein
EP2223122B1 (en) * 2007-12-18 2011-08-31 INSERM (Institut National de la Santé et de la Recherche Médicale) Endogenous morphine or a naturally occuring metabolite thereof as a marker for sepsis
GB0725234D0 (en) * 2007-12-24 2008-02-06 Oxtex Ltd Electrochemical assays
ES2443065T3 (es) * 2008-04-02 2014-02-17 Vivacta Limited Un método para detectar una sustancia química
US8093018B2 (en) 2008-05-20 2012-01-10 Otsuka Pharmaceutical Co., Ltd. Antibody identifying an antigen-bound antibody and an antigen-unbound antibody, and method for preparing the same
FI20085579A0 (fi) * 2008-06-12 2008-06-12 Valtion Teknillinen Kannabiskäytön toteaminen
DE102008049601A1 (de) * 2008-09-30 2010-04-01 Siemens Healthcare Diagnostics Products Gmbh Antikörper zur Bestimmung des Prothrombin-Fragments F2/F1+2 in einem homogenen Immunoassay
MX2011003927A (es) 2009-07-21 2011-07-20 Sekisui Medical Co Ltd Metodo de medicion de insulina.
WO2011053783A2 (en) * 2009-10-30 2011-05-05 Merck Sharp & Dohme Corp. Ax213 and ax132 pcsk9 antagonists and variants
CA2780845C (en) * 2009-11-19 2014-12-30 Proteinexpress Co., Ltd. Fluoroimmunoassay method
US8883978B2 (en) 2010-05-11 2014-11-11 Institute For Cancer Research Antibodies to tumor endothelial marker 7R
US9599608B2 (en) * 2011-09-21 2017-03-21 Fujirebio Inc. Antibody against affinity complex
AU2012325697B2 (en) * 2011-10-21 2015-11-26 Decimadx, Llc Point-of care immunoassay for quantitative small analyte detection
EP2637021A1 (de) 2012-03-06 2013-09-11 Securetec Detektions-Systeme AG Verfahren und Vorrichtung zum Nachweis von Analyten
US9804161B1 (en) 2012-05-14 2017-10-31 Lawrence Livermore National Security, Llc Detector and related, devices, methods and systems
EP2722669A1 (de) 2012-10-22 2014-04-23 Securetec Detektions-Systeme AG Verfahren und Vorrichtung zum Nachweis von illegalen Drogen
JP6673895B2 (ja) 2014-03-21 2020-03-25 エスティー アンド ティー インターナショナル，インコーポレイティド アサ属抽出方法及び組成物
FI126746B (en) 2014-04-07 2017-05-15 Teknologian Tutkimuskeskus Vtt Oy Antibody to HT-2 toxin-HT-2 toxin antibody complex
WO2017053567A1 (en) * 2015-09-22 2017-03-30 Delta Tm Technologies Designing customized protein-specific buffer systems
CA3002903A1 (en) 2015-10-23 2017-04-27 Fred Hutchinson Cancer Research Center Methods to create chemically-induced dimerizing protein systems for regulation of cellular events
CN108779169B (zh) * 2015-12-21 2022-06-07 图尔库大学 针对包含蓝细菌环肽肝毒素的免疫复合物的抗体
AU2017209523A1 (en) * 2016-01-22 2018-08-09 Affimedix, Inc. Device for detection of vitamin D metabolites
AU2017301763B2 (en) * 2016-07-29 2023-07-06 Diazyme Laboratories, Inc. Methods and compositions for assaying vitamin D
IL294218A (en) 2019-12-27 2022-08-01 Chiome Bioscience Inc Antibody against cdcp1
CN116963779A (zh) 2020-09-02 2023-10-27 国立大学法人东京大学 癌症免疫微环境的调节物质及其预防、诊断或治疗
CA3239740A1 (en) * 2021-12-03 2023-06-08 Tim C. LEUTKENS High selective cd229 antigen binding domains and methods of use

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US3996345A (en) * 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US5223441A (en) 1986-10-09 1993-06-29 Syntex (U.S.A.) Inc. Receptors for immune complexes
EP0759976A4 (en) 1994-03-30 2001-02-07 Igen Int Inc THE INSULATION AND PRODUCTION OF CATALYTIC ANTIBODIES USING PHAGENTECHNOLOGY
JP3025633B2 (ja) 1995-12-05 2000-03-27 株式会社蛋白工学研究所 グルタチオン結合活性を有するポリペプチド及びその製造方法
JP4228095B2 (ja) * 1999-12-17 2009-02-25 東ソー株式会社 免疫測定方法および免疫測定試薬
CN1136450C (zh) * 2000-11-03 2004-01-28 厦门大学 具有荧光共振能量转移特征的成对蛋白及其用途

Also Published As

Publication number Publication date
FI20022048A0 (fi) 2002-11-18
JP2006506634A (ja) 2006-02-23
US7749712B2 (en) 2010-07-06
EP1579222B1 (en) 2008-09-10
ES2312828T3 (es) 2009-03-01
NZ539714A (en) 2007-03-30
BRPI0316384B1 (pt) 2016-07-05
NO338417B1 (no) 2016-08-15
BRPI0316384B8 (pt) 2021-07-27
AU2003282143A1 (en) 2004-06-15
CN1711476B (zh) 2010-09-08
WO2004046733A1 (en) 2004-06-03
CN1711476A (zh) 2005-12-21
ATE408146T1 (de) 2008-09-15
BR0316384A (pt) 2005-10-04
CA2503509C (en) 2013-02-05
EP1579222A1 (en) 2005-09-28
NO20052849L (no) 2005-06-13
CA2503509A1 (en) 2004-06-03
US20060246506A1 (en) 2006-11-02
JP4729701B2 (ja) 2011-07-20
DE60323538D1 (de) 2008-10-23
ZA200503475B (en) 2006-07-26
DK1579222T3 (da) 2008-11-17
EA200500643A1 (ru) 2005-12-29
EP1579222B8 (en) 2009-01-07

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