EP0759976A4 - The isolation and production of catalytic antibodies using phage technology - Google Patents
The isolation and production of catalytic antibodies using phage technologyInfo
- Publication number
- EP0759976A4 EP0759976A4 EP94919078A EP94919078A EP0759976A4 EP 0759976 A4 EP0759976 A4 EP 0759976A4 EP 94919078 A EP94919078 A EP 94919078A EP 94919078 A EP94919078 A EP 94919078A EP 0759976 A4 EP0759976 A4 EP 0759976A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- isolation
- production
- catalytic antibodies
- phage technology
- phage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0002—Antibodies with enzymatic activity, e.g. abzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1994/003420 WO1995027045A1 (en) | 1994-03-30 | 1994-03-30 | The isolation and production of catalytic antibodies using phage technology |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0759976A1 EP0759976A1 (en) | 1997-03-05 |
EP0759976A4 true EP0759976A4 (en) | 2001-02-07 |
Family
ID=22242396
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP94919078A Withdrawn EP0759976A4 (en) | 1994-03-30 | 1994-03-30 | The isolation and production of catalytic antibodies using phage technology |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0759976A4 (en) |
JP (1) | JPH10507341A (en) |
AU (1) | AU695406B2 (en) |
WO (1) | WO1995027045A1 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE386802T1 (en) | 1997-06-12 | 2008-03-15 | Novartis Int Pharm Ltd | ARTIFICIAL ANTIBODIES POLYPEPTIDES |
AU5122499A (en) | 1998-07-27 | 2000-02-21 | Genentech Inc. | Improved transformation efficiency in phage display through modification of a coat protein |
AU7786701A (en) | 2000-07-11 | 2002-01-21 | Res Corp Technologies Inc | Artificial antibody polypeptides |
DE60224720D1 (en) | 2001-11-22 | 2008-03-06 | Univ Keio | Re |
AU2003243436A1 (en) | 2002-06-06 | 2003-12-22 | Shohei Koide | Reconstituted polypeptides |
FI20022048A0 (en) | 2002-11-18 | 2002-11-18 | Valtion Teknillinen | Non-competitive immunoassay for small assays |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990014430A1 (en) * | 1989-05-16 | 1990-11-29 | Scripps Clinic And Research Foundation | A new method for tapping the immunological repertoire |
WO1993012232A1 (en) * | 1991-12-10 | 1993-06-24 | Dana Farber Cancer Institute | Reactive neutralizing human anti-gp120 recombinant antibody, dna coding the same and use thereof |
US5258289A (en) * | 1990-09-05 | 1993-11-02 | Davis Claude G | Method for the selecting of genes encoding catalytic antibodies |
-
1994
- 1994-03-30 WO PCT/US1994/003420 patent/WO1995027045A1/en not_active Application Discontinuation
- 1994-03-30 AU AU70141/94A patent/AU695406B2/en not_active Ceased
- 1994-03-30 EP EP94919078A patent/EP0759976A4/en not_active Withdrawn
- 1994-03-30 JP JP7525622A patent/JPH10507341A/en not_active Ceased
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990014430A1 (en) * | 1989-05-16 | 1990-11-29 | Scripps Clinic And Research Foundation | A new method for tapping the immunological repertoire |
US5258289A (en) * | 1990-09-05 | 1993-11-02 | Davis Claude G | Method for the selecting of genes encoding catalytic antibodies |
WO1993012232A1 (en) * | 1991-12-10 | 1993-06-24 | Dana Farber Cancer Institute | Reactive neutralizing human anti-gp120 recombinant antibody, dna coding the same and use thereof |
Non-Patent Citations (2)
Title |
---|
MCCAFFERTY J ET AL: "SELECTION AND RAPID PURIFICATION OF MURINE ANTIBODY FRAGMENTS THAT BIND A TRANSITION-STATE ANALOG BY PHAGE DISPLAY", APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY,US,CLIFTON, NJ, vol. 47, 1994, pages 157 - 173, XP002913520, ISSN: 0273-2289 * |
See also references of WO9527045A1 * |
Also Published As
Publication number | Publication date |
---|---|
AU695406B2 (en) | 1998-08-13 |
EP0759976A1 (en) | 1997-03-05 |
AU7014194A (en) | 1995-10-23 |
JPH10507341A (en) | 1998-07-21 |
WO1995027045A1 (en) | 1995-10-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19961002 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: IGEN INTERNATIONAL, INC. |
|
RIC1 | Information provided on ipc code assigned before grant |
Free format text: 7C 12N 9/00 A, 7C 07K 16/00 B, 7A 61K 38/43 B |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20001222 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
17Q | First examination report despatched |
Effective date: 20011024 |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7C 07K 16/00 B Ipc: 7C 12N 9/00 A |
|
RTI1 | Title (correction) |
Free format text: THE ISOLATION AND PRODUCTION OF CATALYTIC ANTIBODIES USING PHAGE TECHNOLOGY |
|
RTI1 | Title (correction) |
Free format text: ISOLATION AND PRODUCTION OF CATALYTIC ANTIBODIES USING TWO AFFINITY PEPTIDES IN TANDEM |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20060308 |