NO20052849L - Ikke-kompetitiv immunoassay for sma analytter. - Google Patents
Ikke-kompetitiv immunoassay for sma analytter.Info
- Publication number
- NO20052849L NO20052849L NO20052849A NO20052849A NO20052849L NO 20052849 L NO20052849 L NO 20052849L NO 20052849 A NO20052849 A NO 20052849A NO 20052849 A NO20052849 A NO 20052849A NO 20052849 L NO20052849 L NO 20052849L
- Authority
- NO
- Norway
- Prior art keywords
- analyte
- competitive immunoassay
- small analytes
- binding partner
- binding
- Prior art date
Links
- 238000002967 competitive immunoassay Methods 0.000 title abstract 2
- 230000036963 noncompetitive effect Effects 0.000 title abstract 2
- 239000012491 analyte Substances 0.000 abstract 5
- 102000008394 Immunoglobulin Fragments Human genes 0.000 abstract 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/6857—Antibody fragments
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/946—CNS-stimulants, e.g. cocaine, amphetamines
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/948—Sedatives, e.g. cannabinoids, barbiturates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9486—Analgesics, e.g. opiates, aspirine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
- G01N2470/04—Sandwich assay format
- G01N2470/06—Second binding partner specifically binding complex of analyte with first binding partner
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Anesthesiology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Wrappers (AREA)
Abstract
SAMMENDRAG Foreliggende oppfinnelse er rettet på et ikke kompetitivt immunoassay for små analytter, hvori analytten omsettes med to bindingspartnere. Den første bindingspartner bindes til analytten for å danne et kompleks mellom den første bindingspartner og analytten, og den andre bindingspartner bindes til komplekset dannet av den første bindingspartner og analytten. Det resulterende kompleks dannet mellom analytten og bindingspartner blir detektert. Bindingspartnerne er proteiner, så som antistoffer inkludert antistoffragmenter. Oppfinnelsen angår videre reagenspar og testsett som er nyttige i assayene, så vel som anvendelse av reagensparene og til en fremgangsmåte for deres fremstilling. Nye reagenser og midler for deres fremstilling er også tilveiebragt.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI20022048A FI20022048A0 (fi) | 2002-11-18 | 2002-11-18 | Ei-kompetetiivinen immunomääritys pienille analyyteille |
PCT/FI2003/000875 WO2004046733A1 (en) | 2002-11-18 | 2003-11-17 | Non-competitive immunoassay for small analytes |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20052849L true NO20052849L (no) | 2005-06-13 |
NO338417B1 NO338417B1 (no) | 2016-08-15 |
Family
ID=8564953
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20052849A NO338417B1 (no) | 2002-11-18 | 2005-06-13 | Ikke-kompetitiv immunoassay for små analytter. |
Country Status (17)
Country | Link |
---|---|
US (1) | US7749712B2 (no) |
EP (1) | EP1579222B8 (no) |
JP (1) | JP4729701B2 (no) |
CN (1) | CN1711476B (no) |
AT (1) | ATE408146T1 (no) |
BR (1) | BRPI0316384B8 (no) |
CA (1) | CA2503509C (no) |
DE (1) | DE60323538D1 (no) |
DK (1) | DK1579222T3 (no) |
EA (1) | EA200500643A1 (no) |
ES (1) | ES2312828T3 (no) |
FI (1) | FI20022048A0 (no) |
MX (1) | MXPA05005288A (no) |
NO (1) | NO338417B1 (no) |
NZ (1) | NZ539714A (no) |
WO (1) | WO2004046733A1 (no) |
ZA (1) | ZA200503475B (no) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030109067A1 (en) * | 2001-12-06 | 2003-06-12 | Immunetech, Inc. | Homogeneous immunoassays for multiple allergens |
JP2007040834A (ja) * | 2005-08-03 | 2007-02-15 | Japan Science & Technology Agency | 免疫測定用試薬 |
FI20075251A0 (fi) | 2007-04-13 | 2007-04-13 | Hytest Oy | Immunomääritys epästabiilien antigeenien määrittämiseksi |
GB0707870D0 (en) * | 2007-04-23 | 2007-05-30 | Selected Antibodies Ltd | Assay Devices and Methods and Components for use Therein |
US20100304411A1 (en) * | 2007-12-18 | 2010-12-02 | Justus-Liebig Universitat | Endogenous Morphine or a Naturally Occurring Metabolite Thereof as a Marker for Infection |
GB0725234D0 (en) * | 2007-12-24 | 2008-02-06 | Oxtex Ltd | Electrochemical assays |
EP2265951B1 (en) * | 2008-04-02 | 2014-01-08 | Vivacta Limited | A method for sensing a chemical |
US8093018B2 (en) | 2008-05-20 | 2012-01-10 | Otsuka Pharmaceutical Co., Ltd. | Antibody identifying an antigen-bound antibody and an antigen-unbound antibody, and method for preparing the same |
FI20085579A0 (fi) * | 2008-06-12 | 2008-06-12 | Valtion Teknillinen | Kannabiskäytön toteaminen |
DE102008049601A1 (de) * | 2008-09-30 | 2010-04-01 | Siemens Healthcare Diagnostics Products Gmbh | Antikörper zur Bestimmung des Prothrombin-Fragments F2/F1+2 in einem homogenen Immunoassay |
MX2011003927A (es) * | 2009-07-21 | 2011-07-20 | Sekisui Medical Co Ltd | Metodo de medicion de insulina. |
WO2011053783A2 (en) * | 2009-10-30 | 2011-05-05 | Merck Sharp & Dohme Corp. | Ax213 and ax132 pcsk9 antagonists and variants |
KR101335560B1 (ko) * | 2009-11-19 | 2013-12-31 | 우시오덴키 가부시키가이샤 | 형광 면역 측정 방법 |
US8883978B2 (en) | 2010-05-11 | 2014-11-11 | Institute For Cancer Research | Antibodies to tumor endothelial marker 7R |
AU2012310880B2 (en) * | 2011-09-21 | 2015-12-03 | Fujirebio Inc. | Antibody against affinity complex |
US20130102003A1 (en) * | 2011-10-21 | 2013-04-25 | Decimadx, Llc | Point-of-Care Immunoassay for Quantitative Small Analyte Detection |
EP2637021A1 (de) | 2012-03-06 | 2013-09-11 | Securetec Detektions-Systeme AG | Verfahren und Vorrichtung zum Nachweis von Analyten |
US9804161B1 (en) * | 2012-05-14 | 2017-10-31 | Lawrence Livermore National Security, Llc | Detector and related, devices, methods and systems |
EP2722669A1 (de) | 2012-10-22 | 2014-04-23 | Securetec Detektions-Systeme AG | Verfahren und Vorrichtung zum Nachweis von illegalen Drogen |
US10307446B2 (en) | 2014-03-21 | 2019-06-04 | St&T International, Inc. | Cannabis extraction method and compositions |
FI126746B (en) | 2014-04-07 | 2017-05-15 | Teknologian Tutkimuskeskus Vtt Oy | Antibody to HT-2 toxin-HT-2 toxin antibody complex |
EP3353547A1 (en) * | 2015-09-22 | 2018-08-01 | Delta TM Technologies | Designing customized protein-specific buffer systems |
EP3365442B8 (en) * | 2015-10-23 | 2022-06-08 | Fred Hutchinson Cancer Center | Methods to create chemically-induced dimerizing protein systems for regulation of cellular events |
EP3394097A1 (en) | 2015-12-21 | 2018-10-31 | Turun Yliopisto | Antibodies against immunocomplexes comprising cyanobacterial cyclic peptide hepatotoxins |
AU2017209523A1 (en) * | 2016-01-22 | 2018-08-09 | Affimedix, Inc. | Device for detection of vitamin D metabolites |
CA3031355C (en) * | 2016-07-29 | 2023-05-23 | Diazyme Laboratories, Inc. | Methods and compositions for assaying vitamin d |
KR20220119133A (ko) | 2019-12-27 | 2022-08-26 | 치오메 바이오사이언스 가부시키가이샤 | 항 cdcp1 항체 |
JPWO2022049867A1 (no) | 2020-09-02 | 2022-03-10 | ||
WO2023102201A2 (en) * | 2021-12-03 | 2023-06-08 | University Of Utah Research Foundation | High selective cd229 antigen binding domains and methods of use |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3996345A (en) * | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
US5223441A (en) | 1986-10-09 | 1993-06-29 | Syntex (U.S.A.) Inc. | Receptors for immune complexes |
AU695406B2 (en) | 1994-03-30 | 1998-08-13 | Igen International, Inc. | The isolation and production of catalytic antibodies using phage technology |
JP3025633B2 (ja) | 1995-12-05 | 2000-03-27 | 株式会社蛋白工学研究所 | グルタチオン結合活性を有するポリペプチド及びその製造方法 |
JP4228095B2 (ja) * | 1999-12-17 | 2009-02-25 | 東ソー株式会社 | 免疫測定方法および免疫測定試薬 |
CN1136450C (zh) * | 2000-11-03 | 2004-01-28 | 厦门大学 | 具有荧光共振能量转移特征的成对蛋白及其用途 |
-
2002
- 2002-11-18 FI FI20022048A patent/FI20022048A0/fi unknown
-
2003
- 2003-11-17 EP EP03773761A patent/EP1579222B8/en not_active Expired - Lifetime
- 2003-11-17 DE DE60323538T patent/DE60323538D1/de not_active Expired - Lifetime
- 2003-11-17 CA CA2503509A patent/CA2503509C/en not_active Expired - Lifetime
- 2003-11-17 EA EA200500643A patent/EA200500643A1/ru unknown
- 2003-11-17 JP JP2004552756A patent/JP4729701B2/ja not_active Expired - Lifetime
- 2003-11-17 US US10/535,260 patent/US7749712B2/en active Active
- 2003-11-17 ES ES03773761T patent/ES2312828T3/es not_active Expired - Lifetime
- 2003-11-17 NZ NZ539714A patent/NZ539714A/en not_active IP Right Cessation
- 2003-11-17 MX MXPA05005288A patent/MXPA05005288A/es active IP Right Grant
- 2003-11-17 WO PCT/FI2003/000875 patent/WO2004046733A1/en active IP Right Grant
- 2003-11-17 AT AT03773761T patent/ATE408146T1/de not_active IP Right Cessation
- 2003-11-17 DK DK03773761T patent/DK1579222T3/da active
- 2003-11-17 BR BRPI0316384A patent/BRPI0316384B8/pt active IP Right Grant
- 2003-11-17 CN CN2003801034664A patent/CN1711476B/zh not_active Expired - Lifetime
-
2005
- 2005-04-29 ZA ZA200503475A patent/ZA200503475B/en unknown
- 2005-06-13 NO NO20052849A patent/NO338417B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO2004046733A1 (en) | 2004-06-03 |
CN1711476B (zh) | 2010-09-08 |
JP4729701B2 (ja) | 2011-07-20 |
AU2003282143A1 (en) | 2004-06-15 |
ES2312828T3 (es) | 2009-03-01 |
ATE408146T1 (de) | 2008-09-15 |
NZ539714A (en) | 2007-03-30 |
JP2006506634A (ja) | 2006-02-23 |
CN1711476A (zh) | 2005-12-21 |
EP1579222B8 (en) | 2009-01-07 |
CA2503509C (en) | 2013-02-05 |
EP1579222B1 (en) | 2008-09-10 |
EA200500643A1 (ru) | 2005-12-29 |
MXPA05005288A (es) | 2005-08-16 |
BR0316384A (pt) | 2005-10-04 |
ZA200503475B (en) | 2006-07-26 |
US7749712B2 (en) | 2010-07-06 |
DE60323538D1 (de) | 2008-10-23 |
NO338417B1 (no) | 2016-08-15 |
US20060246506A1 (en) | 2006-11-02 |
DK1579222T3 (da) | 2008-11-17 |
EP1579222A1 (en) | 2005-09-28 |
CA2503509A1 (en) | 2004-06-03 |
FI20022048A0 (fi) | 2002-11-18 |
BRPI0316384B8 (pt) | 2021-07-27 |
BRPI0316384B1 (pt) | 2016-07-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20052849L (no) | Ikke-kompetitiv immunoassay for sma analytter. | |
WO2002090983A3 (de) | Quantitaver einschritt immuntest in lyophilisierter form | |
WO2006086208A3 (en) | 5-fluoro-uracil immunoassay | |
WO2007035633A3 (en) | Screening assays and methods | |
WO2005026689A3 (en) | Immunoassay device with immuno-reference electrode | |
WO2007040559A3 (en) | Electrochemiluminescent assay | |
ATE487946T1 (de) | Analytischer sandwichtest zur bestimmung von nt- probnp | |
DE602004001533D1 (de) | Immunotestverfahren für Herz-Troponin I | |
WO2006102200A3 (en) | Docetaxel immunoassay | |
ATE447712T1 (de) | Immunoassay mit doppelter standardkurve | |
EP3300739A3 (en) | Antibodies and related molecules that bind to 161p2f10b proteins | |
AU2002357779A1 (en) | Identification of high affinity molecules by limited dilution screening | |
WO2007054714A3 (en) | Agglutination assay | |
WO2004106385A3 (en) | Monoclonal antibodies specific for buprenorphine and metabolites thereof | |
NO20052553D0 (no) | Cobalaminanalyse. | |
EP1072888A3 (en) | Immunoassay method and reagent for HIV-1p24 antigen | |
NO20052870D0 (no) | Immunoanalysemetode og sett for anvendelse derav | |
WO2006020263A3 (en) | Cytoxan antibodies and immunoassay | |
FI904304A0 (fi) | Foerfarande foer paovisande av analyter. | |
DE60122306D1 (de) | Antikörper, die spezifisch für freies inaktives psa sind, und ihre verwendungen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK1K | Patent expired |