DK1579222T3 - Ikke-kompetitivt immunassay til små analytter - Google Patents

Ikke-kompetitivt immunassay til små analytter

Info

Publication number
DK1579222T3
DK1579222T3 DK03773761T DK03773761T DK1579222T3 DK 1579222 T3 DK1579222 T3 DK 1579222T3 DK 03773761 T DK03773761 T DK 03773761T DK 03773761 T DK03773761 T DK 03773761T DK 1579222 T3 DK1579222 T3 DK 1579222T3
Authority
DK
Denmark
Prior art keywords
analyte
competitive immunoassay
small analytes
binding partner
binding
Prior art date
Application number
DK03773761T
Other languages
English (en)
Inventor
Timo Pulli
Matti Hoeyhtyae
Kristiina Takkinen
Hans Soederlund
Original Assignee
Valtion Teknillinen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valtion Teknillinen filed Critical Valtion Teknillinen
Application granted granted Critical
Publication of DK1579222T3 publication Critical patent/DK1579222T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/6857—Antibody fragments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/946—CNS-stimulants, e.g. cocaine, amphetamines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/948—Sedatives, e.g. cannabinoids, barbiturates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9486—Analgesics, e.g. opiates, aspirine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
    • G01N2470/04—Sandwich assay format
    • G01N2470/06—Second binding partner specifically binding complex of analyte with first binding partner
DK03773761T 2002-11-18 2003-11-17 Ikke-kompetitivt immunassay til små analytter DK1579222T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20022048A FI20022048A0 (fi) 2002-11-18 2002-11-18 Ei-kompetetiivinen immunomääritys pienille analyyteille
PCT/FI2003/000875 WO2004046733A1 (en) 2002-11-18 2003-11-17 Non-competitive immunoassay for small analytes

Publications (1)

Publication Number Publication Date
DK1579222T3 true DK1579222T3 (da) 2008-11-17

Family

ID=8564953

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03773761T DK1579222T3 (da) 2002-11-18 2003-11-17 Ikke-kompetitivt immunassay til små analytter

Country Status (17)

Country Link
US (1) US7749712B2 (da)
EP (1) EP1579222B8 (da)
JP (1) JP4729701B2 (da)
CN (1) CN1711476B (da)
AT (1) ATE408146T1 (da)
BR (1) BRPI0316384B8 (da)
CA (1) CA2503509C (da)
DE (1) DE60323538D1 (da)
DK (1) DK1579222T3 (da)
EA (1) EA200500643A1 (da)
ES (1) ES2312828T3 (da)
FI (1) FI20022048A0 (da)
MX (1) MXPA05005288A (da)
NO (1) NO338417B1 (da)
NZ (1) NZ539714A (da)
WO (1) WO2004046733A1 (da)
ZA (1) ZA200503475B (da)

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US20030109067A1 (en) * 2001-12-06 2003-06-12 Immunetech, Inc. Homogeneous immunoassays for multiple allergens
JP2007040834A (ja) * 2005-08-03 2007-02-15 Japan Science & Technology Agency 免疫測定用試薬
FI20075251A0 (fi) 2007-04-13 2007-04-13 Hytest Oy Immunomääritys epästabiilien antigeenien määrittämiseksi
GB0707870D0 (en) * 2007-04-23 2007-05-30 Selected Antibodies Ltd Assay Devices and Methods and Components for use Therein
US20100304411A1 (en) * 2007-12-18 2010-12-02 Justus-Liebig Universitat Endogenous Morphine or a Naturally Occurring Metabolite Thereof as a Marker for Infection
GB0725234D0 (en) * 2007-12-24 2008-02-06 Oxtex Ltd Electrochemical assays
EP2265951B1 (en) * 2008-04-02 2014-01-08 Vivacta Limited A method for sensing a chemical
US8093018B2 (en) 2008-05-20 2012-01-10 Otsuka Pharmaceutical Co., Ltd. Antibody identifying an antigen-bound antibody and an antigen-unbound antibody, and method for preparing the same
FI20085579A0 (fi) * 2008-06-12 2008-06-12 Valtion Teknillinen Kannabiskäytön toteaminen
DE102008049601A1 (de) * 2008-09-30 2010-04-01 Siemens Healthcare Diagnostics Products Gmbh Antikörper zur Bestimmung des Prothrombin-Fragments F2/F1+2 in einem homogenen Immunoassay
MX2011003927A (es) * 2009-07-21 2011-07-20 Sekisui Medical Co Ltd Metodo de medicion de insulina.
WO2011053783A2 (en) * 2009-10-30 2011-05-05 Merck Sharp & Dohme Corp. Ax213 and ax132 pcsk9 antagonists and variants
KR101335560B1 (ko) * 2009-11-19 2013-12-31 우시오덴키 가부시키가이샤 형광 면역 측정 방법
US8883978B2 (en) 2010-05-11 2014-11-11 Institute For Cancer Research Antibodies to tumor endothelial marker 7R
AU2012310880B2 (en) * 2011-09-21 2015-12-03 Fujirebio Inc. Antibody against affinity complex
US20130102003A1 (en) * 2011-10-21 2013-04-25 Decimadx, Llc Point-of-Care Immunoassay for Quantitative Small Analyte Detection
EP2637021A1 (de) 2012-03-06 2013-09-11 Securetec Detektions-Systeme AG Verfahren und Vorrichtung zum Nachweis von Analyten
US9804161B1 (en) * 2012-05-14 2017-10-31 Lawrence Livermore National Security, Llc Detector and related, devices, methods and systems
EP2722669A1 (de) 2012-10-22 2014-04-23 Securetec Detektions-Systeme AG Verfahren und Vorrichtung zum Nachweis von illegalen Drogen
US10307446B2 (en) 2014-03-21 2019-06-04 St&T International, Inc. Cannabis extraction method and compositions
FI126746B (en) 2014-04-07 2017-05-15 Teknologian Tutkimuskeskus Vtt Oy Antibody to HT-2 toxin-HT-2 toxin antibody complex
EP3353547A1 (en) * 2015-09-22 2018-08-01 Delta TM Technologies Designing customized protein-specific buffer systems
EP3365442B8 (en) * 2015-10-23 2022-06-08 Fred Hutchinson Cancer Center Methods to create chemically-induced dimerizing protein systems for regulation of cellular events
EP3394097A1 (en) 2015-12-21 2018-10-31 Turun Yliopisto Antibodies against immunocomplexes comprising cyanobacterial cyclic peptide hepatotoxins
AU2017209523A1 (en) * 2016-01-22 2018-08-09 Affimedix, Inc. Device for detection of vitamin D metabolites
CA3031355C (en) * 2016-07-29 2023-05-23 Diazyme Laboratories, Inc. Methods and compositions for assaying vitamin d
KR20220119133A (ko) 2019-12-27 2022-08-26 치오메 바이오사이언스 가부시키가이샤 항 cdcp1 항체
JPWO2022049867A1 (da) 2020-09-02 2022-03-10
WO2023102201A2 (en) * 2021-12-03 2023-06-08 University Of Utah Research Foundation High selective cd229 antigen binding domains and methods of use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996345A (en) * 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US5223441A (en) 1986-10-09 1993-06-29 Syntex (U.S.A.) Inc. Receptors for immune complexes
AU695406B2 (en) 1994-03-30 1998-08-13 Igen International, Inc. The isolation and production of catalytic antibodies using phage technology
JP3025633B2 (ja) 1995-12-05 2000-03-27 株式会社蛋白工学研究所 グルタチオン結合活性を有するポリペプチド及びその製造方法
JP4228095B2 (ja) * 1999-12-17 2009-02-25 東ソー株式会社 免疫測定方法および免疫測定試薬
CN1136450C (zh) * 2000-11-03 2004-01-28 厦门大学 具有荧光共振能量转移特征的成对蛋白及其用途

Also Published As

Publication number Publication date
WO2004046733A1 (en) 2004-06-03
CN1711476B (zh) 2010-09-08
JP4729701B2 (ja) 2011-07-20
AU2003282143A1 (en) 2004-06-15
ES2312828T3 (es) 2009-03-01
ATE408146T1 (de) 2008-09-15
NZ539714A (en) 2007-03-30
JP2006506634A (ja) 2006-02-23
CN1711476A (zh) 2005-12-21
EP1579222B8 (en) 2009-01-07
CA2503509C (en) 2013-02-05
EP1579222B1 (en) 2008-09-10
EA200500643A1 (ru) 2005-12-29
MXPA05005288A (es) 2005-08-16
NO20052849L (no) 2005-06-13
BR0316384A (pt) 2005-10-04
ZA200503475B (en) 2006-07-26
US7749712B2 (en) 2010-07-06
DE60323538D1 (de) 2008-10-23
NO338417B1 (no) 2016-08-15
US20060246506A1 (en) 2006-11-02
EP1579222A1 (en) 2005-09-28
CA2503509A1 (en) 2004-06-03
FI20022048A0 (fi) 2002-11-18
BRPI0316384B8 (pt) 2021-07-27
BRPI0316384B1 (pt) 2016-07-05

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