MXPA05003068A - Deteccion de moleculas biologicas por separacion diferencial de sustratos y productos enzimaticos. - Google Patents

Deteccion de moleculas biologicas por separacion diferencial de sustratos y productos enzimaticos.

Info

Publication number
MXPA05003068A
MXPA05003068A MXPA05003068A MXPA05003068A MXPA05003068A MX PA05003068 A MXPA05003068 A MX PA05003068A MX PA05003068 A MXPA05003068 A MX PA05003068A MX PA05003068 A MXPA05003068 A MX PA05003068A MX PA05003068 A MXPA05003068 A MX PA05003068A
Authority
MX
Mexico
Prior art keywords
substrate
enzyme
sample
fluorescence
separation element
Prior art date
Application number
MXPA05003068A
Other languages
English (en)
Spanish (es)
Inventor
J Bowers Raymond
Original Assignee
Univ Kingston
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kingston filed Critical Univ Kingston
Publication of MXPA05003068A publication Critical patent/MXPA05003068A/es

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6486Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56905Protozoa
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56916Enterobacteria, e.g. shigella, salmonella, klebsiella, serratia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6484Optical fibres
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/808Optical sensing apparatus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Genetics & Genomics (AREA)
  • Nanotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
MXPA05003068A 2002-09-20 2003-09-22 Deteccion de moleculas biologicas por separacion diferencial de sustratos y productos enzimaticos. MXPA05003068A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41201502P 2002-09-20 2002-09-20
PCT/CA2003/001439 WO2004027084A1 (en) 2002-09-20 2003-09-22 Detection of biological molecules by differential partitioning of enzyme substrates and products

Publications (1)

Publication Number Publication Date
MXPA05003068A true MXPA05003068A (es) 2005-06-08

Family

ID=32030780

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05003068A MXPA05003068A (es) 2002-09-20 2003-09-22 Deteccion de moleculas biologicas por separacion diferencial de sustratos y productos enzimaticos.

Country Status (10)

Country Link
US (4) US7402426B2 (https=)
EP (1) EP1539986B1 (https=)
JP (2) JP4857434B2 (https=)
AT (1) ATE367449T1 (https=)
AU (1) AU2003266899B2 (https=)
CA (1) CA2497555C (https=)
DE (1) DE60315043T2 (https=)
ES (1) ES2290487T3 (https=)
MX (1) MXPA05003068A (https=)
WO (1) WO2004027084A1 (https=)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7402426B2 (en) 2002-09-20 2008-07-22 Queen's University At Kingston Detection of biological molecules by differential partitioning of enzyme substrates and products
US7964390B2 (en) * 2002-10-11 2011-06-21 Case Western Reserve University Sensor system
US20070026426A1 (en) 2005-04-26 2007-02-01 Applera Corporation System for genetic surveillance and analysis
EP1926825A4 (en) * 2005-09-20 2008-09-24 Univ Arizona State METHODS FOR DETECTING AND CHARACTERIZING MICROORGANISMS
US7812939B2 (en) * 2006-02-13 2010-10-12 Thermo Electron Scientific Instruments Llc Spectrometric measurements during blending / mixing
JP5374809B2 (ja) * 2006-06-29 2013-12-25 パナソニック株式会社 微生物計測システム
US10213164B2 (en) 2008-09-26 2019-02-26 Qualcomm Incorporated Method and apparatus for under-sampled acquisition and transmission of photoplethysmograph (PPG) data and reconstruction of full band PPG data at the receiver
EP2404162B1 (en) 2009-03-03 2017-12-27 Access Medical System Co., Ltd. Detection system and method for high sensitivity fluorescent assays
MX338624B (es) 2009-05-15 2016-04-26 Bio Merieux Inc Aparato automatizado para la deteccion microbiana.
JP2012526996A (ja) 2009-05-15 2012-11-01 ビオメリュー・インコーポレイテッド 試料内の微生物因子の迅速な同定および/または特徴付けのためのシステムおよび方法
US8891086B2 (en) 2009-06-15 2014-11-18 Thermo Scientific Portable Analytical Instruments Inc. Optical scanning systems and methods for measuring a sealed container with a layer for reducing diffusive scattering
FR2949560A1 (fr) * 2009-09-02 2011-03-04 Centre Nat Rech Scient Systeme de spectroscopie a guide d'onde pour l'analyse de particules dans un milieu
JP5747043B2 (ja) * 2009-12-22 2015-07-08 スリーエム イノベイティブ プロパティズ カンパニー 微生物を検出する方法及びそのためのキット
AU2011267803A1 (en) * 2010-06-18 2013-01-31 Pathogen Detection Systems, Inc. An optical pathogen detection system and quality control materials for use in same
CA2802724C (en) 2010-06-18 2016-09-06 Pathogen Detection Systems, Inc. Method and system for detecting biological molecules in samples
JP5621846B2 (ja) * 2010-06-21 2014-11-12 コニカミノルタ株式会社 蛍光測定方法
BR112013010096B1 (pt) 2010-11-01 2020-03-10 3M Innovative Properties Company Método de detecção de uma atividade biológica
CN103189524B (zh) 2010-11-01 2015-01-28 3M创新有限公司 生物灭菌指示器及其使用方法
US9435739B2 (en) 2010-11-24 2016-09-06 3M Innovative Properties Company Methods and compositions to detect a biological activity
US9164086B2 (en) 2011-10-18 2015-10-20 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. Fluorescent dyes with phosphorylated hydroxymethyl groups and their use in light microscopy and imaging techniques
KR101343353B1 (ko) 2012-05-04 2013-12-20 한국과학기술연구원 엔테로박터 및 에스케리키아의 구별 방법
WO2014093926A1 (en) * 2012-12-14 2014-06-19 Larson Bryan Dual medicament carpule for dental syringes
EP2954102B1 (en) * 2013-02-08 2018-12-19 Bio-Rad Laboratories, Inc. Affinity-based partition assay for detection of target molecules
CN104034705B (zh) * 2013-03-06 2017-05-10 常州欣宏科生物化学有限公司 一种荧光探针检测酶活性方法
JP6567274B2 (ja) * 2014-12-10 2019-08-28 水ing株式会社 分離膜の汚染状態分析方法、その方法を用いるろ過対象水の水質評価方法
KR20240160238A (ko) * 2015-08-03 2024-11-08 와이에스아이 인코포레이티드 다중 파라미터 수질 모니터링을 위한 다중 여기-다중 방출 형광계
US11656180B2 (en) 2015-08-03 2023-05-23 Ysi, Inc. Multi excitation-multi emission fluorometer for multiparameter water quality monitoring
CA3102240A1 (en) * 2018-06-01 2019-12-05 Orb Xyz, Inc. Detecting an analyte in a medium
JP6935883B2 (ja) * 2018-07-13 2021-09-15 五稜化薬株式会社 蛍光画像診断の前処理方法
CN110763823B (zh) * 2019-11-22 2022-04-12 威海精讯畅通电子科技有限公司 一种手持式土壤快速检测仪及检测方法
CN114428070B (zh) * 2021-12-28 2024-05-17 南京师范大学 一种检测革兰氏阴性菌的分子印迹荧光纳米粒子及其制备方法

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2856251A1 (de) * 1978-12-27 1980-07-17 Max Planck Gesellschaft Fuellungen fuer indikatorraeume
DK256581A (da) * 1980-06-13 1981-12-14 Nat Res Dev Bindingsanalyse
GB2078370A (en) 1980-06-13 1982-01-06 Nat Res Dev Binding assays
AT377095B (de) * 1982-11-23 1985-02-11 List Hans Sensorelement zur bestimmung des o2-gehaltes einer probe sowie verfahren zur herstellung desselben
US5238809A (en) * 1986-02-03 1993-08-24 Avl Medical Instruments Ag Method for optical determination of the catalytic enzyme activity and arrangement for implementing this method
AT392539B (de) * 1986-02-03 1991-04-25 Avl Verbrennungskraft Messtech Verfahren zur optischen bestimmung der katalytischen enzymaktivitaet einer probe, und eine anordnung zur durchfuehrung des verfahrens
JPS62203047A (ja) * 1986-02-28 1987-09-07 Advance:Kk アンモニアセンサ−
US4712865A (en) * 1987-01-05 1987-12-15 Baxter Travenol Laboratories Dye containing silicon polymer composition
JPH0814541B2 (ja) * 1987-04-03 1996-02-14 ティーディーケイ株式会社 光フアイバ−センサ−
JPS6463842A (en) * 1987-09-03 1989-03-09 Terumo Corp Method and apparatus for measuring concentration of optical material
US4974929A (en) * 1987-09-22 1990-12-04 Baxter International, Inc. Fiber optical probe connector for physiologic measurement devices
FR2650076B1 (fr) * 1989-07-20 1991-10-04 Commissariat Energie Atomique Capteur chimique actif a fibre optique et son procede de fabrication
JP3065639B2 (ja) 1990-08-22 2000-07-17 三菱電線工業株式会社 ケーブル事故検出装置
US5376551A (en) * 1991-03-12 1994-12-27 University Of Utah Research Foundation Apparatus for using fluorescently labeled ligands in studying interaction of a native ligand and its receptor
WO1992016648A1 (en) * 1991-03-18 1992-10-01 Environmental Test Systems, Inc. Chemiluminescent test for microorganisms
JP3048672B2 (ja) * 1991-04-30 2000-06-05 栄研化学株式会社 試薬結合ポリマー、該ポリマー膜および該ポリマーを含む担持体
GB9116909D0 (en) 1991-08-06 1991-09-18 Salford Ultrafine Chem & Res Morphine derivatives
GB9215973D0 (en) * 1992-07-28 1992-09-09 Univ Manchester Sensor devices
US5364767A (en) * 1993-02-11 1994-11-15 Research Organics, In. Chromogenic compounds and methods of using same
GB9315183D0 (en) * 1993-07-22 1993-09-08 British Nuclear Fuels Plc Biosensors
JPH07147997A (ja) * 1993-11-26 1995-06-13 Apere:Kk 微生物検査方法および微生物検査装置
DE69519747T2 (de) * 1994-11-07 2001-08-09 Studie- En Samenwerkingverband Vlaams Water, Antwerpen Enzymatisches verfahren zum nachweis coliformer bakterien oder e.coli
CA2232714A1 (en) * 1995-09-29 1997-04-03 Mark W. Pierson Self-contained incubator for growth of microorganism
DE69633573T2 (de) * 1995-11-22 2005-10-06 Medtronic MiniMed, Inc., Northridge Detektion von biologischen molekülen unter verwendung von chemischer amplifikation und optischem sensor
JPH09152433A (ja) * 1995-11-30 1997-06-10 Aisin Seiki Co Ltd 固相担体に固定した核酸等の検出方法
US5972595A (en) * 1997-12-19 1999-10-26 Nen Life Science Products, Inc. Enzyme assay using a solid phase substrate
US6372895B1 (en) * 2000-07-07 2002-04-16 3M Innovative Properties Company Fluorogenic compounds
JP3759039B2 (ja) * 2000-05-11 2006-03-22 松下エコシステムズ株式会社 化学センサデバイス
WO2002074694A2 (en) * 2001-03-16 2002-09-26 Ewatertek Inc. System and method for monitoring water quality and transmitting water quality data
EP1519678A2 (en) * 2001-10-02 2005-04-06 Alfred E. Mann Institute for Biomedical Engineering at the University of Southern California Internal biochemical sensing device
CA2469845A1 (en) * 2001-12-06 2003-06-19 Purdue Research Foundation Mesoporous membrane collector and separator for airborne pathogen detection
EP1493015A4 (en) * 2002-04-05 2006-01-04 Powerzyme Inc ANALYTE DETECTOR
US20040047535A1 (en) * 2002-09-09 2004-03-11 Ljerka Ukrainczyk Enhanced fiber-optic sensor
US7402426B2 (en) 2002-09-20 2008-07-22 Queen's University At Kingston Detection of biological molecules by differential partitioning of enzyme substrates and products

Also Published As

Publication number Publication date
US7402426B2 (en) 2008-07-22
ATE367449T1 (de) 2007-08-15
US20130217041A1 (en) 2013-08-22
DE60315043D1 (de) 2007-08-30
EP1539986A1 (en) 2005-06-15
AU2003266899A1 (en) 2004-04-08
WO2004027084A1 (en) 2004-04-01
CA2497555A1 (en) 2004-04-01
US20040106164A1 (en) 2004-06-03
AU2003266899B2 (en) 2008-02-28
JP2005538728A (ja) 2005-12-22
EP1539986B1 (en) 2007-07-18
US8377686B2 (en) 2013-02-19
US8632966B2 (en) 2014-01-21
US20140295403A1 (en) 2014-10-02
HK1080514A1 (en) 2006-04-28
US20090117600A1 (en) 2009-05-07
CA2497555C (en) 2013-06-11
ES2290487T3 (es) 2008-02-16
DE60315043T2 (de) 2008-04-10
JP5799353B2 (ja) 2015-10-21
JP4857434B2 (ja) 2012-01-18
JP2011254816A (ja) 2011-12-22

Similar Documents

Publication Publication Date Title
US8632966B2 (en) Detection of biological molecules by differential partitioning of enzyme substrates and products
JP3010565B2 (ja) 微生物検出用装置および方法
KR970003150B1 (ko) 미생물 검출 장치 및 기기
EP0538450A1 (en) Method and apparatus to detect bacterial contamination of transfusable blood
US5372784A (en) Measurement of bacterial CO2 production in an isolated fluorophore by monitoring an absorbance regulated change of fluorescence
EP0472622B1 (en) Apparatus for detection of microorganisms
Magrisso et al. Fiber-optic biosensor to assess circulating phagocyte activity by chemiluminescence
AU652423B2 (en) Measurement of bacterial CO2 production in an isolated fluorophore by monitoring an absorbance regulated change of fluorescence
EP2582784A2 (en) An optical pathogen detection system and quality control materials for use in same
Class et al. Patent application title: DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS
HK1080514B (en) Detection of biological molecules by differential partitioning of enzyme substrates and products
GB2261729A (en) Method and optical probe for the determination of reduced nicotinamide adenine dinucleotide in a sample
CN121577878A (zh) 一种微生物无标记快速检测系统、方法及其应用

Legal Events

Date Code Title Description
FG Grant or registration