MXPA05001573A - Combinacion novedosa de glucocorticoides e inhibidores de pde-4 para tratar enfermedades respiratorias, enfermedades alergicas, asma y copd. - Google Patents

Combinacion novedosa de glucocorticoides e inhibidores de pde-4 para tratar enfermedades respiratorias, enfermedades alergicas, asma y copd.

Info

Publication number
MXPA05001573A
MXPA05001573A MXPA05001573A MXPA05001573A MXPA05001573A MX PA05001573 A MXPA05001573 A MX PA05001573A MX PA05001573 A MXPA05001573 A MX PA05001573A MX PA05001573 A MXPA05001573 A MX PA05001573A MX PA05001573 A MXPA05001573 A MX PA05001573A
Authority
MX
Mexico
Prior art keywords
diseases
pde
copd
asthma
novel combination
Prior art date
Application number
MXPA05001573A
Other languages
English (en)
Inventor
Robert Hermann
Original Assignee
Viatris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viatris Gmbh filed Critical Viatris Gmbh
Publication of MXPA05001573A publication Critical patent/MXPA05001573A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La invencion se relaciona con una combinacion novedosa de un grucocorticoide, especialmente loteprednol y por lo menos un inhibidor de fosfodiesterasa-4 (inhibidor de PDE-4), especialmente un derivado de hidroxiindol de N-(3, 5 -dicloropiridin- 4-il)-2-[l-(4 -fluorobencil)-5 -hidroxiindol -3-il)-2 -oxoacetamida para administracion simultanea, secuencial o separada en el tratamiento de enfermedades respiratorias, enfermedades alergicas, asma y enfermedades pulmonares obstructivas cronicas (COPD).
MXPA05001573A 2002-08-09 2003-08-04 Combinacion novedosa de glucocorticoides e inhibidores de pde-4 para tratar enfermedades respiratorias, enfermedades alergicas, asma y copd. MXPA05001573A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10236688 2002-08-09
PCT/EP2003/008607 WO2004019984A1 (de) 2002-08-09 2003-08-04 Neue kombination von glucocorticoiden und pde-4-inhibitoren zur behandlung von atemwegserkrankungen, allergischen erkrankungen, asthma und copd

Publications (1)

Publication Number Publication Date
MXPA05001573A true MXPA05001573A (es) 2005-04-25

Family

ID=31968961

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05001573A MXPA05001573A (es) 2002-08-09 2003-08-04 Combinacion novedosa de glucocorticoides e inhibidores de pde-4 para tratar enfermedades respiratorias, enfermedades alergicas, asma y copd.

Country Status (19)

Country Link
US (1) US20050288265A1 (es)
EP (1) EP1526870B1 (es)
JP (1) JP2005539042A (es)
CN (1) CN1308038C (es)
AT (1) ATE361076T1 (es)
AU (1) AU2003255365B2 (es)
CA (1) CA2492645A1 (es)
CY (1) CY1107696T1 (es)
DE (1) DE50307184D1 (es)
DK (1) DK1526870T3 (es)
EA (1) EA008981B1 (es)
ES (1) ES2285238T3 (es)
HK (1) HK1078463A1 (es)
HR (1) HRP20050224B1 (es)
MX (1) MXPA05001573A (es)
NO (1) NO20051212D0 (es)
PT (1) PT1526870E (es)
UA (1) UA82323C2 (es)
WO (1) WO2004019984A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10241407A1 (de) * 2002-09-06 2004-03-18 Elbion Ag Behandlung nicht allergischer Rhinitis durch selektive Phosphodiesterase 4-Hemmstoffe
WO2005074918A1 (en) 2004-02-06 2005-08-18 Benzstrasse 1 D-61352 Bad Homburd The combination of anticholinergics and glucocorticoids for the long-term treatment of asthma and copd
CN101518532A (zh) * 2004-02-06 2009-09-02 Meda制药有限及两合公司 用于呼吸道疾病治疗的抗胆碱能药和4型磷酸二酯酶抑制剂的组合
PL1863476T3 (pl) * 2005-03-16 2016-07-29 Meda Pharma Gmbh & Co Kg Skojarzenie środków antycholinergicznych i antagonistów receptora leukotrienowego do leczenia chorób układu oddechowego
US8506934B2 (en) 2005-04-29 2013-08-13 Robert I. Henkin Methods for detection of biological substances
EP1971369B1 (en) 2005-12-21 2009-08-19 MEDA Pharma GmbH & Co. KG Combination of r,r-glycopyrrolate, rolipram and budesonide for the treatment of inflammatory diseases
US20070213296A1 (en) * 2006-03-07 2007-09-13 Yanzhen Zhang Compositions and methods for the treatment of immunoinflammatory disorders
WO2008095136A2 (en) 2007-01-31 2008-08-07 Henkin Robert I Methods for detection of biological substances
US8580801B2 (en) 2008-07-23 2013-11-12 Robert I. Henkin Phosphodiesterase inhibitor treatment
CN102309756A (zh) * 2010-07-02 2012-01-11 天津金耀集团有限公司 含有磷酸二酯酶4抑制剂和糖皮质激素的治疗皮肤病的复方药物
US11596599B2 (en) 2012-05-03 2023-03-07 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
CA2871745C (en) * 2012-05-03 2023-01-24 Kala Pharmaceuticals, Inc. Pharmaceutical nanoparticles showing improved mucosal transport
US9827191B2 (en) 2012-05-03 2017-11-28 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
KR102140989B1 (ko) 2012-05-03 2020-08-04 칼라 파마슈티컬스, 인크. 개선된 점막 수송을 나타내는 제약 나노입자
US10864219B2 (en) 2012-05-03 2020-12-15 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
US20160030435A1 (en) * 2013-03-15 2016-02-04 Robert I HENKIN Phosphodiesterase inhibitor treatment
EP3108245B1 (en) 2014-02-18 2020-07-22 Robert I. Henkin Methods and compositions for diagnosing and treating loss and/or distortion of taste or smell

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4996335A (en) * 1980-07-10 1991-02-26 Nicholas S. Bodor Soft steroids having anti-inflammatory activity
SE449106B (sv) * 1980-07-10 1987-04-06 Otsuka Pharma Co Ltd Steroid med anti-inflammatorisk verkan samt komposition innehallande denna
AU718967B2 (en) * 1997-02-05 2000-05-04 Jagotec Ag Medical aerosol formulations
ES2262072T3 (es) * 1998-04-28 2006-11-16 Elbion Ag Derivados de indol y su utilizacion como inhibidores de la fosfodiesterasa 4.
DE19917504A1 (de) * 1999-04-17 2000-10-19 Dresden Arzneimittel Verwendung von Hydroxyindolen, die Inhibitoren der Phosphodiesterase 4 sind, zur Therapie chronisch obstruktiver Lungenerkrankungen
DE19947234A1 (de) * 1999-09-30 2001-04-05 Asta Medica Ag Neue Kombination von Loteprednol und Antihistaminika
ECSP003747A (es) * 1999-11-02 2002-05-23 Smithkline Beecham Corp Metodo y composiciones para el tratamiento de las enfermedades pulmonares
US20040214805A1 (en) * 1999-11-02 2004-10-28 Smithkline Beecham Corporation Method and compositions for treating pulmonary diseases
DK1289945T3 (da) * 2000-05-19 2004-11-01 Alcon Inc Anilindisulfidderivater til behandling af allergiske sygdomme
GB0123951D0 (en) * 2001-10-05 2001-11-28 Glaxo Group Ltd Therapies for treating respiratory diseases
JP5116940B2 (ja) * 2001-11-05 2013-01-09 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング ヒドラゾノ−マロニトリル類
US20030092706A1 (en) * 2001-11-09 2003-05-15 Johannes Barsig Combination

Also Published As

Publication number Publication date
JP2005539042A (ja) 2005-12-22
HRP20050224A2 (en) 2005-04-30
HK1078463A1 (en) 2006-03-17
EP1526870A1 (de) 2005-05-04
ES2285238T3 (es) 2007-11-16
NO20051212L (no) 2005-03-08
EA200500328A1 (ru) 2005-06-30
CN1674939A (zh) 2005-09-28
PT1526870E (pt) 2007-07-09
DK1526870T3 (da) 2007-09-10
EP1526870B1 (de) 2007-05-02
ATE361076T1 (de) 2007-05-15
CA2492645A1 (en) 2004-03-11
US20050288265A1 (en) 2005-12-29
CY1107696T1 (el) 2013-04-18
HRP20050224B1 (en) 2007-12-31
DE50307184D1 (de) 2007-06-14
AU2003255365A1 (en) 2004-03-19
WO2004019984A1 (de) 2004-03-11
AU2003255365B2 (en) 2009-02-19
CN1308038C (zh) 2007-04-04
EA008981B1 (ru) 2007-10-26
UA82323C2 (uk) 2008-04-10
NO20051212D0 (no) 2005-03-08

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