MXPA04004064A - Derivados heteroaromaticos de carboxamida para el tratramiento de la inflamacion. - Google Patents

Derivados heteroaromaticos de carboxamida para el tratramiento de la inflamacion.

Info

Publication number
MXPA04004064A
MXPA04004064A MXPA04004064A MXPA04004064A MXPA04004064A MX PA04004064 A MXPA04004064 A MX PA04004064A MX PA04004064 A MXPA04004064 A MX PA04004064A MX PA04004064 A MXPA04004064 A MX PA04004064A MX PA04004064 A MXPA04004064 A MX PA04004064A
Authority
MX
Mexico
Prior art keywords
inflammation
carboxamide derivatives
treatment
heteroaromatic carboxamide
heteroaromatic
Prior art date
Application number
MXPA04004064A
Other languages
English (en)
Spanish (es)
Inventor
Thao D Perry
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of MXPA04004064A publication Critical patent/MXPA04004064A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
MXPA04004064A 2001-10-30 2002-10-30 Derivados heteroaromaticos de carboxamida para el tratramiento de la inflamacion. MXPA04004064A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34081601P 2001-10-30 2001-10-30
PCT/US2002/034801 WO2003037886A2 (fr) 2001-10-30 2002-10-30 Derives de carboxamide heteroaromatique destines au traitement des inflammations

Publications (1)

Publication Number Publication Date
MXPA04004064A true MXPA04004064A (es) 2004-09-06

Family

ID=23335051

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04004064A MXPA04004064A (es) 2001-10-30 2002-10-30 Derivados heteroaromaticos de carboxamida para el tratramiento de la inflamacion.

Country Status (7)

Country Link
EP (1) EP1444010A2 (fr)
JP (1) JP2005509645A (fr)
AU (1) AU2002356871A1 (fr)
BR (1) BR0213734A (fr)
CA (1) CA2464924A1 (fr)
MX (1) MXPA04004064A (fr)
WO (1) WO2003037886A2 (fr)

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JP2006512313A (ja) 2002-10-31 2006-04-13 アムジェン インコーポレイテッド 抗炎症剤
CA2534127A1 (fr) * 2003-07-31 2005-02-10 Boehringer Ingelheim Pharmaceuticals, Inc. Composes de benzothiophene substitues et utilisations
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WO2005056562A1 (fr) 2003-12-05 2005-06-23 Boehringer Ingelheim Pharmaceuticals, Inc. Composes amide d'acide 3-amino-thieno[2,3-b] pyridine-2-carboxylique substitue servant d'inhibiteurs d'ikk
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PE20060748A1 (es) 2004-09-21 2006-10-01 Smithkline Beecham Corp Derivados de indolcarboxamida como inhibidores de quinasa ikk2
MX2007012116A (es) 2005-03-29 2008-04-08 Icos Corp Derivados de heteroaril urea utiles para inhibir chk1.
GB0507200D0 (en) * 2005-04-08 2005-05-18 Smithkline Beecham Corp Chemical compounds
US8063071B2 (en) 2007-10-31 2011-11-22 GlaxoSmithKline, LLC Chemical compounds
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CA2637335A1 (fr) 2006-01-23 2007-08-02 Vertex Pharmaceuticals Incorporated Thiophene-carboxamides utiles en tant qu'inhibiteurs de proteines kinases
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US8853244B2 (en) 2006-05-23 2014-10-07 Vertex Pharmaceuticals Incorporated Thiophene-carboxamides useful as inhibitors of protein kinases
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CA2653654A1 (fr) 2006-06-06 2007-12-21 Boehringer Ingelheim International Gmbh Composes amide de l'acide 3-amino-thieno[2,3-b]pyridine-2-carboxylique substitues, procedes de preparation et leurs utilisations
WO2008020622A1 (fr) * 2006-08-17 2008-02-21 Kyorin Pharmaceutical Co., Ltd. NOUVEAU COMPOSÉ DE THIÉNO[2,3-d]PYRIMIDINE
PE20081679A1 (es) 2006-12-07 2008-12-18 Hoffmann La Roche Compuestos del inhibidor de fosfoinositida 3-cinasa y metodos de uso
AR065804A1 (es) 2007-03-23 2009-07-01 Smithkline Beecham Corp Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento
US7893059B2 (en) 2007-09-24 2011-02-22 Genentech, Inc. Thiazolopyrimidine PI3K inhibitor compounds and methods of use
WO2009085983A1 (fr) 2007-12-19 2009-07-09 Genentech, Inc. 5-anilinoimidazopyridines et procédés d'utilisation
WO2009082687A1 (fr) 2007-12-21 2009-07-02 Genentech, Inc. Azaindolizines et procédés d'utilisation
BRPI1008749B8 (pt) 2009-02-05 2021-05-25 Immunogen Inc compostos derivados de benzodiazepina, seus conjugados, composição farmacêutica, seu uso e seus processos de preparação
WO2010102968A1 (fr) 2009-03-10 2010-09-16 Glaxo Group Limited Dérivés d'indole comme inhibiteurs de ikk2
CA2753285A1 (fr) 2009-03-12 2010-09-16 Genentech, Inc. Combinaisons de composes inhibiteurs de phosphoinositide 3-kinase et d'agents chimiotherapeutiques pour le traitement de tumeurs malignes hematopoietiques
JP2012524066A (ja) * 2009-04-16 2012-10-11 テリック，インコーポレイテッド チューブリン重合阻害剤としての置換４−アミノ−５−ベンゾイル−２−（フェニルアミノ）チオフェン−３−カルボニトリルおよび置換４−アミノ−５−ベンゾイル−２−（フェニルアミノ）チオフェン−３−カルボキサミド
BR112012006802A2 (pt) 2009-09-28 2020-08-18 F.Hoffmann-La Roche Ag composto, composição farmacêutica, método para tratar câncer, usos de um composto, kit e invenção
WO2011049625A1 (fr) 2009-10-20 2011-04-28 Mansour Samadpour Procédé de criblage d'aflatoxine dans des produits
JP5889795B2 (ja) 2009-11-05 2016-03-22 ライゼン・ファーマシューティカルズ・エスアー 新規キナーゼモジュレーター
MX341687B (es) 2010-02-10 2016-08-30 Immunogen Inc "anticuerpos cd20 y su utilización".
EP3666289A1 (fr) 2011-02-15 2020-06-17 ImmunoGen, Inc. Dérivés de benzodiazépine cytotoxique
PT2705029T (pt) 2011-05-04 2019-02-01 Rhizen Pharmaceuticals S A Novos compostos como moduladores de proteína quinases
KR101909801B1 (ko) 2012-06-08 2018-10-18 에프. 호프만-라 로슈 아게 암의 치료를 위한 포스포이노시타이드 3 키나제 억제제 화합물 및 화학치료제의 돌연변이체 선택성 및 조합물
HUE034591T2 (en) 2012-07-04 2018-02-28 Rhizen Pharmaceuticals S A Selective PI3K delta inhibitors
EP2887965A1 (fr) 2012-08-22 2015-07-01 ImmunoGen, Inc. Dérivés de benzodiazépine cytotoxique
WO2014134483A2 (fr) 2013-02-28 2014-09-04 Immunogen, Inc. Conjugués comprenant des agents de liaison cellulaire (cba) et des agents cytotoxiques
US9901647B2 (en) 2013-02-28 2018-02-27 Immunogen, Inc. Conjugates comprising cell-binding agents and cytotoxic agents
WO2014194030A2 (fr) 2013-05-31 2014-12-04 Immunogen, Inc. Conjugués comprenant des agents de liaison cellulaire et des agents cytotoxiques
AR104068A1 (es) 2015-03-26 2017-06-21 Hoffmann La Roche Combinaciones de un compuesto inhibidor de fosfoinosítido 3-cinasa y un compuesto inhibidor de cdk4/6 para el tratamiento del cáncer
EP3507305A1 (fr) 2016-09-02 2019-07-10 Dana-Farber Cancer Institute, Inc. Composition et méthodes de traitement des déreglements des lymphocytes b
WO2018204775A1 (fr) 2017-05-05 2018-11-08 Hepanova, Inc. Composés amino-aryl-benzamide et leurs procédés d'utilisation

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DE4019168A1 (de) * 1989-06-19 1990-12-20 Ciba Geigy Ag Azofarbstoffe, deren herstellung und verwendung
GB0003154D0 (en) * 2000-02-12 2000-04-05 Astrazeneca Uk Ltd Novel compounds
JP2002105081A (ja) * 2000-07-28 2002-04-10 Nikken Chem Co Ltd 新規チオフェンニ環化合物
AU2002211663A1 (en) * 2000-10-12 2002-04-22 Smith Kline Beecham Corporation Nf-$g(k)b inhibitors
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WO2003028731A1 (fr) * 2001-10-04 2003-04-10 Smithkline Beecham Corporation Inhibiteurs de kinase chk1

Also Published As

Publication number Publication date
EP1444010A2 (fr) 2004-08-11
AU2002356871A1 (en) 2003-05-12
CA2464924A1 (fr) 2003-05-08
BR0213734A (pt) 2004-10-19
WO2003037886A2 (fr) 2003-05-08
JP2005509645A (ja) 2005-04-14
WO2003037886A3 (fr) 2003-12-24

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