MXPA03012011A - Nuevos compuestos de pirido-pirido-pirrolo[3,2-g]pirrolo[3,4-e]indol y pirido [3,4-c]carbazol, un proceso para su preparacion y las composiciones farmaceuticas que los contienen. - Google Patents

Nuevos compuestos de pirido-pirido-pirrolo[3,2-g]pirrolo[3,4-e]indol y pirido [3,4-c]carbazol, un proceso para su preparacion y las composiciones farmaceuticas que los contienen.

Info

Publication number
MXPA03012011A
MXPA03012011A MXPA03012011A MXPA03012011A MXPA03012011A MX PA03012011 A MXPA03012011 A MX PA03012011A MX PA03012011 A MXPA03012011 A MX PA03012011A MX PA03012011 A MXPA03012011 A MX PA03012011A MX PA03012011 A MXPA03012011 A MX PA03012011A
Authority
MX
Mexico
Prior art keywords
pyrrolo
pyrido
derivatives
represent
indole
Prior art date
Application number
MXPA03012011A
Other languages
English (en)
Inventor
Renard Pierre
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of MXPA03012011A publication Critical patent/MXPA03012011A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)

Abstract

Se describen los compuestos de la formula (I) en donde: W1 y W2 representan, con los atomos de carbono a los cuales estan enlazados, un grupo fenilo o un grupo piridinilo, y al menos uno de los grupos W1 o W2 representan un grupo piridinilo, R1 y R2 cada uno representan un grupo de la formula U-V como se define en la descripcion, X y X1 representan cada uno un atomo de hidrogeno, un grupo hidroxilo, alcoxi, mercapto o alquiltio,; Y e Y1 representan cada uno un atomo de hidrogeno; o X e Y, X1 e Y1 representan, junto con el atomo de carbono que estos incluyen, un grupo carbonilo o tiocarbonilo; R4 y R5 son como se definen en la descripcion; Q1, Q2 representan un atomo de hidrogeno, o Q1 y Q2, junto con los atomos de carbono que estos incluyen, forman un enlace aromatico. Los compuestos de la invencion son utilizados en medicamentos.
MXPA03012011A 2001-06-29 2002-06-28 Nuevos compuestos de pirido-pirido-pirrolo[3,2-g]pirrolo[3,4-e]indol y pirido [3,4-c]carbazol, un proceso para su preparacion y las composiciones farmaceuticas que los contienen. MXPA03012011A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0108615A FR2826653B1 (fr) 2001-06-29 2001-06-29 Nouveaux derives de pyrido-pyrido-pyrrolo[3,2-g]pyrrolo [3,4-e]-indole et pyrido-pyrrolo[2,3-a]pyrrolo[3,4-c] carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2002/002250 WO2003002563A1 (fr) 2001-06-29 2002-06-28 Derives de pyrido-pyrido-pyrrolo pyrrolo-indole et pyrido-pyrrolo pyrrolo carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
MXPA03012011A true MXPA03012011A (es) 2004-03-26

Family

ID=8864927

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03012011A MXPA03012011A (es) 2001-06-29 2002-06-28 Nuevos compuestos de pirido-pirido-pirrolo[3,2-g]pirrolo[3,4-e]indol y pirido [3,4-c]carbazol, un proceso para su preparacion y las composiciones farmaceuticas que los contienen.

Country Status (19)

Country Link
US (1) US7001906B2 (es)
EP (1) EP1409486A1 (es)
JP (1) JP2004535450A (es)
KR (1) KR100577543B1 (es)
CN (1) CN1275966C (es)
AR (1) AR036159A1 (es)
BR (1) BR0210698A (es)
CA (1) CA2452192A1 (es)
CZ (1) CZ2004143A3 (es)
EA (1) EA007221B1 (es)
FR (1) FR2826653B1 (es)
HU (1) HUP0400347A2 (es)
MX (1) MXPA03012011A (es)
NO (1) NO20035722D0 (es)
NZ (1) NZ530322A (es)
PL (1) PL366381A1 (es)
SK (1) SK692004A3 (es)
WO (1) WO2003002563A1 (es)
ZA (1) ZA200309514B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1506192B1 (en) 2002-05-08 2008-02-27 Janssen Pharmaceutica N.V. Substituted pyrroline kinase inhibitors
EP1611132A1 (en) * 2003-03-27 2006-01-04 Janssen Pharmaceutica N.V. Substituted pyrroline kinase inhibitors
BRPI0513899A (pt) 2004-07-27 2008-05-20 Sgx Pharmaceuticals Inc moduladores de cinase heterocìclica de anel fundido
US7361764B2 (en) 2004-07-27 2008-04-22 Sgx Pharmaceuticals, Inc. Pyrrolo-pyridine kinase modulators
US7626021B2 (en) 2004-07-27 2009-12-01 Sgx Pharmaceuticals, Inc. Fused ring heterocycle kinase modulators
NZ553267A (en) 2004-07-27 2010-09-30 Sgx Pharmaceuticals Inc Pyrrolo-pyridine kinase modulators
US8008320B2 (en) * 2004-12-08 2011-08-30 Johannes Gutenberg-Universitatis 3-(indolyl)-4-arylmaleimide derivatives and their use as angiogenesis inhibitors
TWI499414B (zh) 2006-09-29 2015-09-11 Lexicon Pharmaceuticals Inc 鈉與葡萄糖第２型共同運輸體（ｃｏ-ｔｒａｎｓｐｏｒｔｅｒ ２）的抑制物與其應用方法
WO2008109591A1 (en) * 2007-03-08 2008-09-12 Lexicon Pharmaceuticals, Inc. Phlorizin analogs as inhibitors of sodium glucose co-transporter 2
HUE059861T2 (hu) * 2007-04-11 2023-01-28 Canbas Co Ltd N-Szubsztituált 2,5-dioxo-azolin vegyületek a rák kezelésében való felhasználásra
CN101234112B (zh) * 2008-03-03 2010-10-13 中国科学院化学研究所 阳离子咔唑类化合物的制药用途
CN103934464B (zh) * 2013-12-04 2016-01-20 宁波大学 一种咔唑吡啶银纳米棒及其制备方法
US10435365B2 (en) 2014-03-16 2019-10-08 Hadasit Medical Research Services And Development Ltd. Type III deiodinase inhibitors and uses thereof
AR107030A1 (es) 2015-12-09 2018-03-14 Padlock Therapeutics Inc Inhibidores aza-bencimidazol de pad4
CN112739345A (zh) 2017-11-06 2021-04-30 斯奈普生物公司 Pim激酶抑制剂组合物，方法和其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL101554A0 (en) * 1991-04-11 1992-12-30 Schering Corp Anti-tumor and anti-psoriatic compositions
GB9319297D0 (en) * 1993-09-17 1993-11-03 Wellcome Found Indole derivatives
GB9416467D0 (en) * 1994-08-13 1994-10-05 Wellcome Found Compounds for use in medicine
US5705511A (en) * 1994-10-14 1998-01-06 Cephalon, Inc. Fused pyrrolocarbazoles
ATE293254T1 (de) * 1998-08-26 2005-04-15 Cephalon Inc Modulierung von mlk- (multiple lineage kinase) proteinen
FR2801054B1 (fr) * 1999-11-17 2003-06-13 Adir Nouveaux derives de 12,13-(pyranosyl)-indolo[2,3-a]pyrrolo [3,4-c]carbazole et 12,13-(pyranosyl)-furo[3,4-c]indolo [2,3-a]carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
EA200301301A1 (ru) 2004-06-24
SK692004A3 (en) 2004-07-07
FR2826653A1 (fr) 2003-01-03
CA2452192A1 (fr) 2003-01-09
CN1520415A (zh) 2004-08-11
EP1409486A1 (fr) 2004-04-21
NO20035722D0 (no) 2003-12-19
JP2004535450A (ja) 2004-11-25
US20040152721A1 (en) 2004-08-05
CZ2004143A3 (cs) 2004-05-12
FR2826653B1 (fr) 2005-10-14
EA007221B1 (ru) 2006-08-25
PL366381A1 (en) 2005-01-24
KR100577543B1 (ko) 2006-05-10
NZ530322A (en) 2005-06-24
US7001906B2 (en) 2006-02-21
CN1275966C (zh) 2006-09-20
WO2003002563A1 (fr) 2003-01-09
HUP0400347A2 (hu) 2004-09-28
KR20040018397A (ko) 2004-03-03
AR036159A1 (es) 2004-08-18
BR0210698A (pt) 2004-09-21
ZA200309514B (en) 2004-12-08

Similar Documents

Publication Publication Date Title
MXPA03012011A (es) Nuevos compuestos de pirido-pirido-pirrolo[3,2-g]pirrolo[3,4-e]indol y pirido [3,4-c]carbazol, un proceso para su preparacion y las composiciones farmaceuticas que los contienen.
MXPA05011597A (es) Derivados de aminopropanol como moduladores del receptor 1-fosfato de esfingosina.
MXPA05011596A (es) Derivados de amino-propanol como modulador de receptor de esfingosina-1-fosfato.
MXPA05013348A (es) Derivados de amino-propanol como moduladores del receptor de esfingosina-1-fosfato.
PT1753712E (pt) Derivados de amino-propanol
TW200505920A (en) Organic compounds
RS20060129A (en) /1,8/naphthyridin-2-ones and related compounds for the treatment of schizophrenia
WO2004098518A3 (en) Pyrazole-amide compounds useful as kinase inhibitors
TW200607801A (en) Pyrimidine derivatives for the treatment of abnormal cell growth
IL185611A0 (en) Novel imidazo[1,5-a]pyridine derivatives, method for preparing same and pharmaceutical compositions containing same
BG106440A (en) Nitrogen-heterocyclic derivatives as nos inhibitors
TW200612949A (en) Pyrimidine derivatives for the treatment of abnormal cell growth
MY142423A (en) Substituted aminoacetyl pyrrolidine compounds which are dipeptidyl peptidase iv inhibitors, and pharmaceutical compositions containing them
IL173810A0 (en) Imidazopyridine derivatives and pharmaceutical compositions containing the same
DE602004024213D1 (en) Aminopropanolderivate
TW200714598A (en) Urea derivatives, methods for their manufacture, and uses therefor
PL1831202T3 (pl) Pochodne pirolidyniowe jako receptory M3 muskarynowe
MY150497A (en) New camptothecin analogue compounds, a process for their preparation and pharmaceutical compositions containing them
JO2616B1 (ar) مركبات ثلاثية الحلقات جديدة، طريقة من أجل تحضيرها ومركباتها الصيدلانية
GB0323204D0 (en) Organic compounds
MXPA05013823A (es) Derivados de pirrolidinio y piperidino como ligandos para el receptor m3 muscarinico.
IL173895A0 (en) Imidazopyridine derivatives and pharmaceutical compositions containing the same
GB0428418D0 (en) Organic compounds
EP1555261A4 (en) VALEROLACTONE COMPOUNDS AND FRAGRANCE COMPOSITION
MXPA03001356A (es) Nuevos agentes inhibidores de beta-amiloides, procedimientos para su preparacion y su uso como medicamentos.