MXPA03011032A - Activadores de derivados de oxazol/tiazol del receptor hppar-alfa. - Google Patents
Activadores de derivados de oxazol/tiazol del receptor hppar-alfa.Info
- Publication number
- MXPA03011032A MXPA03011032A MXPA03011032A MXPA03011032A MXPA03011032A MX PA03011032 A MXPA03011032 A MX PA03011032A MX PA03011032 A MXPA03011032 A MX PA03011032A MX PA03011032 A MXPA03011032 A MX PA03011032A MX PA03011032 A MXPA03011032 A MX PA03011032A
- Authority
- MX
- Mexico
- Prior art keywords
- hppar
- oxazol
- thiazol
- halogen
- alpha receptor
- Prior art date
Links
- ZCQWOFVYLHDMMC-UHFFFAOYSA-N Oxazole Chemical compound C1=COC=N1 ZCQWOFVYLHDMMC-UHFFFAOYSA-N 0.000 title 1
- 239000012190 activator Substances 0.000 title 1
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 150000001721 carbon Chemical group 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 125000004076 pyridyl group Chemical group 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0113231.5A GB0113231D0 (en) | 2001-05-31 | 2001-05-31 | Chemical compounds |
| PCT/EP2002/005886 WO2002096895A1 (en) | 2001-05-31 | 2002-05-29 | Oxazol/ thiazol-derivatives activators of the hppar-alpha receptor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA03011032A true MXPA03011032A (es) | 2004-03-19 |
Family
ID=9915636
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA03011032A MXPA03011032A (es) | 2001-05-31 | 2002-05-29 | Activadores de derivados de oxazol/tiazol del receptor hppar-alfa. |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US7157479B2 (enExample) |
| EP (1) | EP1399430B1 (enExample) |
| JP (1) | JP2004532267A (enExample) |
| KR (1) | KR100859591B1 (enExample) |
| CN (1) | CN1307166C (enExample) |
| AR (1) | AR034051A1 (enExample) |
| AU (1) | AU2002317765B2 (enExample) |
| BR (1) | BR0209785A (enExample) |
| CA (1) | CA2448205A1 (enExample) |
| CO (1) | CO5540297A2 (enExample) |
| CY (1) | CY1107206T1 (enExample) |
| CZ (1) | CZ20033252A3 (enExample) |
| DE (1) | DE60223805T2 (enExample) |
| DK (1) | DK1399430T3 (enExample) |
| ES (1) | ES2296965T3 (enExample) |
| GB (1) | GB0113231D0 (enExample) |
| HU (1) | HUP0400043A3 (enExample) |
| IL (1) | IL158929A0 (enExample) |
| MX (1) | MXPA03011032A (enExample) |
| MY (1) | MY132656A (enExample) |
| NO (1) | NO20035209L (enExample) |
| NZ (1) | NZ529754A (enExample) |
| PL (1) | PL367248A1 (enExample) |
| PT (1) | PT1399430E (enExample) |
| SI (1) | SI1399430T1 (enExample) |
| TW (1) | TWI245760B (enExample) |
| WO (1) | WO2002096895A1 (enExample) |
| ZA (1) | ZA200309095B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA04003398A (es) * | 2001-10-12 | 2004-11-22 | Nippon Chemiphar Co | Activador para el receptor o activado con el proliferador de peroxisoma. |
| AU2003261935A1 (en) | 2002-09-06 | 2004-03-29 | Takeda Pharmaceutical Company Limited | Furan or thiophene derivative and medicinal use thereof |
| GB0314370D0 (en) * | 2003-06-19 | 2003-07-23 | Glaxo Group Ltd | Chemical compounds |
| GB0323702D0 (en) * | 2003-10-09 | 2003-11-12 | Smithkline Beecham Corp | Chemical compound |
| NZ546444A (en) | 2003-11-05 | 2009-09-25 | Hoffmann La Roche | Phenyl derivatives as PPAR agonists |
| FR2882359A1 (fr) * | 2005-02-24 | 2006-08-25 | Negma Lerads Soc Par Actions S | Derives activateurs de ppar, procede de preparation et application en therapeutique |
| CN101007790B (zh) * | 2006-01-27 | 2011-03-30 | 北京摩力克科技有限公司 | 草氨酸衍生物、其制备方法和医药用途 |
| FR2901792A1 (fr) * | 2006-06-06 | 2007-12-07 | Negma Lerads Soc Par Actions S | DERIVES ACTIVATEURS DE PPARs, PROCEDE DE PREPARATION ET APPLICATION EN THERAPEUTIQUE |
| JP5357894B2 (ja) | 2008-12-01 | 2013-12-04 | 田辺三菱製薬株式会社 | チアゾール環を含むカルボン酸誘導体およびその医薬用途 |
| CN110803996B (zh) * | 2019-11-13 | 2022-01-11 | 台州市创源工业技术有限公司 | 一种羟基苄胺的合成方法 |
| CN116511225B (zh) * | 2023-03-30 | 2025-09-23 | 江南大学 | 一种油酸基des液体及其制备方法和它在厌氧发酵液高效浓缩中的应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2263721A1 (en) * | 1996-08-19 | 1998-02-26 | Satoshi Ohrui | Propionic acid derivatives and applications thereof |
| US6506757B1 (en) | 1998-03-10 | 2003-01-14 | Ono Pharmaceutical Co., Ltd. | Carboxylic acid derivatives and drugs containing the same as the active ingredient |
| EE200100558A (et) * | 1999-04-28 | 2002-12-16 | Aventis Pharma Deutschland Gmbh | Triarüülhappe derivaat, seda sisaldav farmatseutiline kompositsioon ja ühendi raviotstarbeline kasutamine |
| GB9914977D0 (en) * | 1999-06-25 | 1999-08-25 | Glaxo Group Ltd | Chemical compounds |
| DE60005973T2 (de) | 1999-08-27 | 2004-05-13 | Eli Lilly And Co., Indianapolis | Biaryl-oxa(thia)zolderivate und ihre verwendung als ppars modulatoren |
| PE20011010A1 (es) * | 1999-12-02 | 2001-10-18 | Glaxo Group Ltd | Oxazoles y tiazoles sustituidos como agonista del receptor activado por el proliferador de peroxisomas humano |
| GB0113233D0 (en) * | 2001-05-31 | 2001-07-25 | Glaxo Group Ltd | Chemical compounds |
-
2001
- 2001-05-31 GB GBGB0113231.5A patent/GB0113231D0/en not_active Ceased
-
2002
- 2002-05-29 EP EP02747331A patent/EP1399430B1/en not_active Expired - Lifetime
- 2002-05-29 PL PL02367248A patent/PL367248A1/xx not_active Application Discontinuation
- 2002-05-29 ES ES02747331T patent/ES2296965T3/es not_active Expired - Lifetime
- 2002-05-29 CZ CZ20033252A patent/CZ20033252A3/cs unknown
- 2002-05-29 NZ NZ529754A patent/NZ529754A/en unknown
- 2002-05-29 SI SI200230654T patent/SI1399430T1/sl unknown
- 2002-05-29 IL IL15892902A patent/IL158929A0/xx unknown
- 2002-05-29 BR BR0209785-0A patent/BR0209785A/pt not_active IP Right Cessation
- 2002-05-29 CA CA002448205A patent/CA2448205A1/en not_active Abandoned
- 2002-05-29 US US10/478,936 patent/US7157479B2/en not_active Expired - Fee Related
- 2002-05-29 AU AU2002317765A patent/AU2002317765B2/en not_active Ceased
- 2002-05-29 JP JP2003500074A patent/JP2004532267A/ja active Pending
- 2002-05-29 PT PT02747331T patent/PT1399430E/pt unknown
- 2002-05-29 MY MYPI20021973A patent/MY132656A/en unknown
- 2002-05-29 HU HU0400043A patent/HUP0400043A3/hu unknown
- 2002-05-29 WO PCT/EP2002/005886 patent/WO2002096895A1/en not_active Ceased
- 2002-05-29 AR ARP020101999A patent/AR034051A1/es unknown
- 2002-05-29 DK DK02747331T patent/DK1399430T3/da active
- 2002-05-29 TW TW091111392A patent/TWI245760B/zh not_active IP Right Cessation
- 2002-05-29 DE DE60223805T patent/DE60223805T2/de not_active Expired - Fee Related
- 2002-05-29 CN CNB028149424A patent/CN1307166C/zh not_active Expired - Fee Related
- 2002-05-29 MX MXPA03011032A patent/MXPA03011032A/es active IP Right Grant
- 2002-05-29 KR KR1020037015678A patent/KR100859591B1/ko not_active Expired - Fee Related
-
2003
- 2003-11-21 ZA ZA200309095A patent/ZA200309095B/en unknown
- 2003-11-24 NO NO20035209A patent/NO20035209L/no not_active Application Discontinuation
- 2003-12-03 CO CO03106490A patent/CO5540297A2/es not_active Application Discontinuation
-
2008
- 2008-02-19 CY CY20081100202T patent/CY1107206T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |