DK1399430T3 - Oxazol/thiazolderivataktivatorer af HPPAR-alfa-receptoren - Google Patents
Oxazol/thiazolderivataktivatorer af HPPAR-alfa-receptorenInfo
- Publication number
- DK1399430T3 DK1399430T3 DK02747331T DK02747331T DK1399430T3 DK 1399430 T3 DK1399430 T3 DK 1399430T3 DK 02747331 T DK02747331 T DK 02747331T DK 02747331 T DK02747331 T DK 02747331T DK 1399430 T3 DK1399430 T3 DK 1399430T3
- Authority
- DK
- Denmark
- Prior art keywords
- oxazole
- alpha receptor
- thiazole derivative
- hppar alpha
- activators
- Prior art date
Links
- ZCQWOFVYLHDMMC-UHFFFAOYSA-N Oxazole Chemical compound C1=COC=N1 ZCQWOFVYLHDMMC-UHFFFAOYSA-N 0.000 title 1
- 239000012190 activator Substances 0.000 title 1
- 150000007979 thiazole derivatives Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0113231.5A GB0113231D0 (en) | 2001-05-31 | 2001-05-31 | Chemical compounds |
| PCT/EP2002/005886 WO2002096895A1 (en) | 2001-05-31 | 2002-05-29 | Oxazol/ thiazol-derivatives activators of the hppar-alpha receptor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1399430T3 true DK1399430T3 (da) | 2008-03-25 |
Family
ID=9915636
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02747331T DK1399430T3 (da) | 2001-05-31 | 2002-05-29 | Oxazol/thiazolderivataktivatorer af HPPAR-alfa-receptoren |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US7157479B2 (enExample) |
| EP (1) | EP1399430B1 (enExample) |
| JP (1) | JP2004532267A (enExample) |
| KR (1) | KR100859591B1 (enExample) |
| CN (1) | CN1307166C (enExample) |
| AR (1) | AR034051A1 (enExample) |
| AU (1) | AU2002317765B2 (enExample) |
| BR (1) | BR0209785A (enExample) |
| CA (1) | CA2448205A1 (enExample) |
| CO (1) | CO5540297A2 (enExample) |
| CY (1) | CY1107206T1 (enExample) |
| CZ (1) | CZ20033252A3 (enExample) |
| DE (1) | DE60223805T2 (enExample) |
| DK (1) | DK1399430T3 (enExample) |
| ES (1) | ES2296965T3 (enExample) |
| GB (1) | GB0113231D0 (enExample) |
| HU (1) | HUP0400043A3 (enExample) |
| IL (1) | IL158929A0 (enExample) |
| MX (1) | MXPA03011032A (enExample) |
| MY (1) | MY132656A (enExample) |
| NO (1) | NO20035209L (enExample) |
| NZ (1) | NZ529754A (enExample) |
| PL (1) | PL367248A1 (enExample) |
| PT (1) | PT1399430E (enExample) |
| SI (1) | SI1399430T1 (enExample) |
| TW (1) | TWI245760B (enExample) |
| WO (1) | WO2002096895A1 (enExample) |
| ZA (1) | ZA200309095B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003033493A1 (en) * | 2001-10-12 | 2003-04-24 | Nippon Chemiphar Co.,Ltd. | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR δ |
| EP1535915A4 (en) | 2002-09-06 | 2005-10-05 | Takeda Pharmaceutical | FURANOIC OR THIOPHENE DERIVATIVES AND THEIR MEDICAL USE |
| GB0314370D0 (en) * | 2003-06-19 | 2003-07-23 | Glaxo Group Ltd | Chemical compounds |
| GB0323702D0 (en) * | 2003-10-09 | 2003-11-12 | Smithkline Beecham Corp | Chemical compound |
| KR100847976B1 (ko) | 2003-11-05 | 2008-07-22 | 에프. 호프만-라 로슈 아게 | Ｐｐａｒ 작용제로서 페닐 유도체 |
| FR2882359A1 (fr) * | 2005-02-24 | 2006-08-25 | Negma Lerads Soc Par Actions S | Derives activateurs de ppar, procede de preparation et application en therapeutique |
| CN101007790B (zh) * | 2006-01-27 | 2011-03-30 | 北京摩力克科技有限公司 | 草氨酸衍生物、其制备方法和医药用途 |
| FR2901792A1 (fr) * | 2006-06-06 | 2007-12-07 | Negma Lerads Soc Par Actions S | DERIVES ACTIVATEURS DE PPARs, PROCEDE DE PREPARATION ET APPLICATION EN THERAPEUTIQUE |
| CA2744985C (en) | 2008-12-01 | 2014-05-06 | Mitsubishi Tanabe Pharma Corporation | Carboxylic acid derivative containing thiazole ring useful for the prevention or treatment of hyperlipidemia |
| CN110803996B (zh) * | 2019-11-13 | 2022-01-11 | 台州市创源工业技术有限公司 | 一种羟基苄胺的合成方法 |
| CN116511225B (zh) * | 2023-03-30 | 2025-09-23 | 江南大学 | 一种油酸基des液体及其制备方法和它在厌氧发酵液高效浓缩中的应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0930299A1 (en) * | 1996-08-19 | 1999-07-21 | Japan Tobacco Inc. | Propionic acid derivatives and applications thereof |
| DE69941777D1 (de) * | 1998-03-10 | 2010-01-21 | Ono Pharmaceutical Co | Carbonsäurederivate und medikamente die diese als aktiven wirkstoff enthalten |
| AU782404B2 (en) * | 1999-04-28 | 2005-07-28 | Sanofi-Aventis Deutschland Gmbh | Tri-aryl acid derivatives as PPAR receptor ligands |
| GB9914977D0 (en) * | 1999-06-25 | 1999-08-25 | Glaxo Group Ltd | Chemical compounds |
| DK1206457T3 (da) | 1999-08-27 | 2004-02-16 | Lilly Co Eli | Biaryl-oxa(thia)zolderivater og deres anvendelse som modulatorer PPAP'ER |
| PE20011010A1 (es) * | 1999-12-02 | 2001-10-18 | Glaxo Group Ltd | Oxazoles y tiazoles sustituidos como agonista del receptor activado por el proliferador de peroxisomas humano |
| GB0113233D0 (en) * | 2001-05-31 | 2001-07-25 | Glaxo Group Ltd | Chemical compounds |
-
2001
- 2001-05-31 GB GBGB0113231.5A patent/GB0113231D0/en not_active Ceased
-
2002
- 2002-05-29 PT PT02747331T patent/PT1399430E/pt unknown
- 2002-05-29 WO PCT/EP2002/005886 patent/WO2002096895A1/en not_active Ceased
- 2002-05-29 DE DE60223805T patent/DE60223805T2/de not_active Expired - Fee Related
- 2002-05-29 TW TW091111392A patent/TWI245760B/zh not_active IP Right Cessation
- 2002-05-29 CA CA002448205A patent/CA2448205A1/en not_active Abandoned
- 2002-05-29 MY MYPI20021973A patent/MY132656A/en unknown
- 2002-05-29 HU HU0400043A patent/HUP0400043A3/hu unknown
- 2002-05-29 DK DK02747331T patent/DK1399430T3/da active
- 2002-05-29 AU AU2002317765A patent/AU2002317765B2/en not_active Ceased
- 2002-05-29 KR KR1020037015678A patent/KR100859591B1/ko not_active Expired - Fee Related
- 2002-05-29 ES ES02747331T patent/ES2296965T3/es not_active Expired - Lifetime
- 2002-05-29 JP JP2003500074A patent/JP2004532267A/ja active Pending
- 2002-05-29 IL IL15892902A patent/IL158929A0/xx unknown
- 2002-05-29 EP EP02747331A patent/EP1399430B1/en not_active Expired - Lifetime
- 2002-05-29 NZ NZ529754A patent/NZ529754A/en unknown
- 2002-05-29 PL PL02367248A patent/PL367248A1/xx not_active Application Discontinuation
- 2002-05-29 MX MXPA03011032A patent/MXPA03011032A/es active IP Right Grant
- 2002-05-29 CN CNB028149424A patent/CN1307166C/zh not_active Expired - Fee Related
- 2002-05-29 SI SI200230654T patent/SI1399430T1/sl unknown
- 2002-05-29 AR ARP020101999A patent/AR034051A1/es unknown
- 2002-05-29 BR BR0209785-0A patent/BR0209785A/pt not_active IP Right Cessation
- 2002-05-29 CZ CZ20033252A patent/CZ20033252A3/cs unknown
- 2002-05-29 US US10/478,936 patent/US7157479B2/en not_active Expired - Fee Related
-
2003
- 2003-11-21 ZA ZA200309095A patent/ZA200309095B/en unknown
- 2003-11-24 NO NO20035209A patent/NO20035209L/no not_active Application Discontinuation
- 2003-12-03 CO CO03106490A patent/CO5540297A2/es not_active Application Discontinuation
-
2008
- 2008-02-19 CY CY20081100202T patent/CY1107206T1/el unknown
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