MXPA02003114A - Dispersiones para formular ingredientes activos ligeramente o poco solubles. - Google Patents
Dispersiones para formular ingredientes activos ligeramente o poco solubles.Info
- Publication number
- MXPA02003114A MXPA02003114A MXPA02003114A MXPA02003114A MXPA02003114A MX PA02003114 A MXPA02003114 A MX PA02003114A MX PA02003114 A MXPA02003114 A MX PA02003114A MX PA02003114 A MXPA02003114 A MX PA02003114A MX PA02003114 A MXPA02003114 A MX PA02003114A
- Authority
- MX
- Mexico
- Prior art keywords
- slightly
- formulating
- dispersions
- active ingredients
- emulsion
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
Abstract
La presente invencion se refiere a una dispersion que comprende una fase aceitosa y una fase acuosa en la forma de una emulsion aceite/agua o una solucion agua/aceite, por lo menos un ingrediente activo el cual es ligeramente o poco soluble en fases aceitosas y acuosas, ademas de uno o mas emulsificadores y/o estabilizadores opcionales. La dispersion esta desprovista de solventes organicos cuestionables toxicologicamente y contiene una cantidad disuelta de dicho ingrediente activo que es mayor que la cantidad de aditivo obtenida por su solubilidad maxima, tanto en la fase aceitosa como la fase acuosa de la emulsion.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10036871A DE10036871A1 (de) | 2000-07-28 | 2000-07-28 | Dispersionen zur Formulierung wenig oder schwer löslicher Wirkstoffe |
PCT/EP2001/008726 WO2002009667A2 (de) | 2000-07-28 | 2001-07-27 | Dispersionen zur formulierung wenig oder schwer löslicher wirkstoffe |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA02003114A true MXPA02003114A (es) | 2003-04-10 |
Family
ID=7650573
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA02003114A MXPA02003114A (es) | 2000-07-28 | 2001-07-27 | Dispersiones para formular ingredientes activos ligeramente o poco solubles. |
Country Status (15)
Country | Link |
---|---|
US (2) | US7060285B2 (es) |
EP (1) | EP1305006B1 (es) |
JP (1) | JP2004505032A (es) |
KR (1) | KR20020063869A (es) |
CN (1) | CN1620283A (es) |
AT (1) | ATE401055T1 (es) |
AU (1) | AU8976801A (es) |
BR (1) | BR0107042A (es) |
CA (1) | CA2388550A1 (es) |
DE (2) | DE10036871A1 (es) |
ES (1) | ES2307644T3 (es) |
MX (1) | MXPA02003114A (es) |
PL (1) | PL365874A1 (es) |
RU (1) | RU2002111336A (es) |
WO (1) | WO2002009667A2 (es) |
Families Citing this family (60)
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IN188843B (es) * | 2000-06-22 | 2002-11-09 | Vinod Daftary Gautam Dr | |
DE10036871A1 (de) * | 2000-07-28 | 2002-02-14 | Pharmasol Gmbh | Dispersionen zur Formulierung wenig oder schwer löslicher Wirkstoffe |
ATE346590T1 (de) * | 2001-07-26 | 2006-12-15 | Ethypharm Sa | Umgehüllte allylamine oder benzylamine enthaltende granulate, verfahren zur herstellung und in der mundhöhle dispergierbare tabletten enthaltend die umgehüllten granulate |
JP2005513097A (ja) * | 2001-11-01 | 2005-05-12 | イサム・リサーチ・デベロツプメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシテイ・オブ・エルサレム | ドライアイ治療方法および組成物 |
US6656460B2 (en) | 2001-11-01 | 2003-12-02 | Yissum Research Development | Method and composition for dry eye treatment |
US20040022820A1 (en) * | 2001-11-28 | 2004-02-05 | David Anderson | Reversed liquid crystalline phases with non-paraffin hydrophobes |
US20030191093A1 (en) * | 2001-12-03 | 2003-10-09 | Novacea, Inc. | Pharmaceutical compositions comprising active vitamin D compounds |
KR100533458B1 (ko) * | 2002-07-20 | 2005-12-07 | 대화제약 주식회사 | 파클리탁셀의 가용화용 조성물 및 그의 제조 방법 |
KR100587177B1 (ko) * | 2002-09-12 | 2006-06-08 | 한불화장품주식회사 | 히아루론산나트륨을 유화안정화제로 이용한 화장료 조성물 |
US20050026877A1 (en) * | 2002-12-03 | 2005-02-03 | Novacea, Inc. | Pharmaceutical compositions comprising active vitamin D compounds |
WO2004075913A1 (ja) * | 2003-02-28 | 2004-09-10 | Chugai Seiyaku Kabushiki Kaisha | タンパク質含有安定化製剤 |
EP1605931A4 (en) * | 2003-03-13 | 2009-04-29 | Conforma Therapeutics Corp | MEDICINAL FORMULATIONS WITH LONG AND MEDIUM-CHAINED TRIGLYCERIDES |
US20050020546A1 (en) * | 2003-06-11 | 2005-01-27 | Novacea, Inc. | Pharmaceutical compositions comprising active vitamin D compounds |
US20050059583A1 (en) | 2003-09-15 | 2005-03-17 | Allergan, Inc. | Methods of providing therapeutic effects using cyclosporin components |
PE20050596A1 (es) * | 2003-12-19 | 2005-10-18 | Novartis Ag | Microemulsion que comprende un inhibidor renina |
WO2006003519A2 (en) * | 2004-07-02 | 2006-01-12 | Novagali Pharma Sa | Use of emulsions for intra: and periocular injection |
ATE439123T1 (de) * | 2004-07-02 | 2009-08-15 | Novagali Pharma Sa | Verwendung von emulsionen zur intra- und periocularen injection |
US9993558B2 (en) * | 2004-10-01 | 2018-06-12 | Ramscor, Inc. | Sustained release eye drop formulations |
GB0501835D0 (en) * | 2005-01-28 | 2005-03-09 | Unilever Plc | Improvements relating to spray dried compositions |
US7288520B2 (en) * | 2005-07-13 | 2007-10-30 | Allergan, Inc. | Cyclosporin compositions |
US8288348B2 (en) | 2005-07-13 | 2012-10-16 | Allergan, Inc. | Cyclosporin compositions |
NZ592132A (en) * | 2005-08-31 | 2012-12-21 | Abraxis Bioscience Llc | Composition comprising nanoparticles of docitaxel and a citrate |
CN101291659A (zh) * | 2005-08-31 | 2008-10-22 | 阿布拉科斯生物科学有限公司 | 包含水难溶性药剂和抗微生物剂的组合物 |
US20080286325A1 (en) * | 2006-01-05 | 2008-11-20 | Med Institute, Inc. | Cyclodextrin elution media for medical device coatings comprising a taxane therapeutic agent |
US7919108B2 (en) * | 2006-03-10 | 2011-04-05 | Cook Incorporated | Taxane coatings for implantable medical devices |
US7875284B2 (en) * | 2006-03-10 | 2011-01-25 | Cook Incorporated | Methods of manufacturing and modifying taxane coatings for implantable medical devices |
GB0613925D0 (en) * | 2006-07-13 | 2006-08-23 | Unilever Plc | Improvements relating to nanodispersions |
WO2008120249A1 (en) * | 2007-03-30 | 2008-10-09 | Sifi S.P.A. | Pharmaceutical formulations based on apolar and polar lipids for ophthalmic use |
KR100785656B1 (ko) * | 2007-05-14 | 2007-12-17 | 재단법인서울대학교산학협력재단 | 소염제로 사용되는 소디움글리코콜레이트 또는 그 유도체 |
US20140335166A1 (en) * | 2013-05-08 | 2014-11-13 | Michael W. Fountain | Methods of Making and Using Nano Scale Particles |
KR20100017928A (ko) * | 2007-05-25 | 2010-02-16 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 치료제의 경구 투여를 위한 제제 및 관련 방법 |
US8853284B2 (en) | 2008-06-02 | 2014-10-07 | Honeywell International Inc. | Wax dispersion formulations, method of producing same, and uses |
US20100305046A1 (en) | 2009-06-02 | 2010-12-02 | Abbott Medical Optics Inc. | Stable cyclosporine containing ophthalmic emulsion for treating dry eyes |
US9480645B2 (en) * | 2009-06-02 | 2016-11-01 | Abbott Medical Optics Inc. | Omega-3 oil containing ophthalmic emulsions |
AU2014250656B2 (en) * | 2009-06-02 | 2016-05-05 | Johnson & Johnson Surgical Vision, Inc. | Omega-3 oil containing ophthalmic emulsions |
CN101904814A (zh) | 2009-06-04 | 2010-12-08 | 上海恒瑞医药有限公司 | 制备载药乳剂的方法 |
EP2308468A1 (en) * | 2009-10-08 | 2011-04-13 | Novaliq GmbH | Novel pharmaceutical composition comprising a macrolide immunosuppressant drug |
WO2011050457A1 (en) | 2009-10-26 | 2011-05-05 | The University Of British Columbia | Stabilized formulation for oral administration of therapeutic agents and related methods |
TWI438009B (zh) * | 2010-02-19 | 2014-05-21 | Teikoku Pharma Usa Inc | 紫杉烷前-乳劑調配物及其製造與使用之方法 |
CN101816423A (zh) * | 2010-04-22 | 2010-09-01 | 王京南 | 紫苏籽油脂肪乳口服溶液、饮料及制造方法 |
WO2011139899A2 (en) | 2010-05-03 | 2011-11-10 | Teikoku Pharma Usa, Inc. | Non-aqueous taxane pro-emulsion formulations and methods of making and using the same |
CA2823628A1 (en) | 2011-01-05 | 2012-07-12 | Hospira, Inc. | Spray drying vancomycin |
EP2667852B1 (en) * | 2011-01-27 | 2016-11-09 | GlaxoSmithKline Biologicals SA | Adjuvant nanoemulsions with crystallisation inhibitors |
EP2768486B1 (en) * | 2011-10-21 | 2018-10-03 | First Tech International Limited | Tocotrienol compositions |
JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
CN104043104B (zh) | 2013-03-15 | 2018-07-10 | 浙江创新生物有限公司 | 含盐酸万古霉素的喷雾干粉及其工业化制备方法 |
WO2014208901A1 (ko) * | 2013-06-24 | 2014-12-31 | 한국콜마주식회사 | 난용성 의약품의 수중유적형 에멀젼 조성물 및 이의 제조방법 |
CA2961746A1 (en) * | 2014-09-17 | 2016-03-24 | Vivacelle Bio, Inc. | Stable micelle and/or liposome compositions and uses thereof |
MY182652A (en) | 2014-11-25 | 2021-01-27 | Kl Kepong Oleomas Sdn Bhd | Formulation for effective tocotrienol delivery |
US11617724B2 (en) | 2015-05-21 | 2023-04-04 | Dermavant Sciences GmbH | Topical pharmaceutical compositions |
RS63402B1 (sr) | 2015-05-21 | 2022-08-31 | Dermavant Sciences GmbH | Topikalne farmaceutske kompozicije |
EA201792674A1 (ru) * | 2015-05-29 | 2018-04-30 | Окулис Эхф. | Способ образования наночастиц циклоспорина а/циклодекстрина |
CN105769760B (zh) * | 2016-04-14 | 2018-10-12 | 河北科星药业有限公司 | 布帕伐醌注射液及其制备方法 |
EP3471697A1 (en) * | 2016-06-16 | 2019-04-24 | The University of Liverpool | Chemical composition |
BR102017021294A2 (pt) * | 2017-10-04 | 2019-04-24 | Universidade De São Paulo - Usp | Processo de obtenção de carreadores lipídicos nanoestruturados, carreadores lipídicos nanoestruturados obtidos e uso dos mesmos |
US11497718B2 (en) | 2018-11-13 | 2022-11-15 | Dermavant Sciences GmbH | Use of tapinarof for the treatment of atopic dermatitis |
PL428779A1 (pl) * | 2019-01-31 | 2020-08-10 | Gdański Uniwersytet Medyczny | Kompozycja farmaceutyczna w postaci ciekłej zawierająca jako substancję aktywną substancję leczniczą nietrwałą w środowisku wodnym |
GB201904757D0 (en) * | 2019-04-04 | 2019-05-22 | Biorelevant Com Ltd | Biorelevant composition |
CN109989293B (zh) * | 2019-04-26 | 2022-01-04 | 苏州赛维科环保技术服务有限公司 | 一种asa施胶剂乳液及其制备方法 |
WO2023043854A1 (en) * | 2021-09-14 | 2023-03-23 | Nulixir Inc. | Alimentary-related particles, production methods, and production apparatus |
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US4707470A (en) * | 1985-05-17 | 1987-11-17 | Smithkline Beckman Corporation | Polyene antibiotic emulsion formulation |
DE3623376A1 (de) | 1986-07-11 | 1988-01-21 | Behringwerke Ag | Pharmazeutische formulierung und verfahren zu deren herstellung |
GB8714652D0 (en) * | 1987-06-23 | 1987-07-29 | Davis S S | Drug emulsion |
US5651991A (en) * | 1987-10-28 | 1997-07-29 | Nippon Shinyaku Co. Ltd. | Drug carriers |
US5534502A (en) * | 1990-11-06 | 1996-07-09 | Nippon Shinyaku Co. Ltd. | Process for producing fat emulsion |
US5529785A (en) * | 1993-05-12 | 1996-06-25 | Dietl; Hans | Pharmaceutical preparation containing cyclosporin(s) for oral administration and process for producing same |
EP0570829B1 (de) * | 1992-05-18 | 2001-04-25 | CicloMulsion AG | Cyclosporin(e) enthaltende pharmazeutische Zubereitung zur intravenösen Applikation sowie Verfahren zu ihrer Herstellung |
US5916596A (en) * | 1993-02-22 | 1999-06-29 | Vivorx Pharmaceuticals, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
US5622714A (en) * | 1993-05-12 | 1997-04-22 | Dietl; Hans | Pharmaceutical preparation containing cyclosporine(s) for intravenous administration and process for its production |
US5576016A (en) * | 1993-05-18 | 1996-11-19 | Pharmos Corporation | Solid fat nanoemulsions as drug delivery vehicles |
SE9303744D0 (sv) | 1993-11-12 | 1993-11-12 | Astra Ab | Pharmaceutical emulsion |
US5616330A (en) * | 1994-07-19 | 1997-04-01 | Hemagen/Pfc | Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same |
DE4440337A1 (de) | 1994-11-11 | 1996-05-15 | Dds Drug Delivery Services Ges | Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit |
US5660858A (en) * | 1996-04-03 | 1997-08-26 | Research Triangle Pharmaceuticals | Cyclosporin emulsions |
DE10036871A1 (de) * | 2000-07-28 | 2002-02-14 | Pharmasol Gmbh | Dispersionen zur Formulierung wenig oder schwer löslicher Wirkstoffe |
-
2000
- 2000-07-28 DE DE10036871A patent/DE10036871A1/de not_active Withdrawn
-
2001
- 2001-07-27 DE DE50114130T patent/DE50114130D1/de not_active Revoked
- 2001-07-27 BR BR0107042-8A patent/BR0107042A/pt not_active IP Right Cessation
- 2001-07-27 US US09/915,549 patent/US7060285B2/en not_active Expired - Lifetime
- 2001-07-27 AT AT01969541T patent/ATE401055T1/de not_active IP Right Cessation
- 2001-07-27 JP JP2002515220A patent/JP2004505032A/ja active Pending
- 2001-07-27 KR KR1020027004005A patent/KR20020063869A/ko not_active Application Discontinuation
- 2001-07-27 ES ES01969541T patent/ES2307644T3/es not_active Expired - Lifetime
- 2001-07-27 RU RU2002111336/14A patent/RU2002111336A/ru not_active Application Discontinuation
- 2001-07-27 CA CA002388550A patent/CA2388550A1/en not_active Abandoned
- 2001-07-27 CN CNA018029477A patent/CN1620283A/zh active Pending
- 2001-07-27 WO PCT/EP2001/008726 patent/WO2002009667A2/de active IP Right Grant
- 2001-07-27 EP EP01969541A patent/EP1305006B1/de not_active Revoked
- 2001-07-27 PL PL01365874A patent/PL365874A1/xx not_active Application Discontinuation
- 2001-07-27 AU AU89768/01A patent/AU8976801A/en not_active Abandoned
- 2001-07-27 MX MXPA02003114A patent/MXPA02003114A/es unknown
-
2006
- 2006-04-24 US US11/408,967 patent/US7744909B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1620283A (zh) | 2005-05-25 |
WO2002009667A3 (de) | 2002-11-07 |
AU8976801A (en) | 2002-02-13 |
PL365874A1 (en) | 2005-01-10 |
WO2002009667A9 (de) | 2002-02-28 |
DE10036871A1 (de) | 2002-02-14 |
EP1305006B1 (de) | 2008-07-16 |
US7744909B2 (en) | 2010-06-29 |
BR0107042A (pt) | 2002-06-04 |
EP1305006A2 (de) | 2003-05-02 |
US20060188534A1 (en) | 2006-08-24 |
RU2002111336A (ru) | 2003-11-20 |
US20030059470A1 (en) | 2003-03-27 |
KR20020063869A (ko) | 2002-08-05 |
DE50114130D1 (de) | 2008-08-28 |
US7060285B2 (en) | 2006-06-13 |
ATE401055T1 (de) | 2008-08-15 |
WO2002009667A2 (de) | 2002-02-07 |
CA2388550A1 (en) | 2002-02-07 |
JP2004505032A (ja) | 2004-02-19 |
ES2307644T3 (es) | 2008-12-01 |
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