MXPA01010640A - Medicion y uso de interacciones moleculares. - Google Patents

Medicion y uso de interacciones moleculares.

Info

Publication number
MXPA01010640A
MXPA01010640A MXPA01010640A MXPA01010640A MXPA01010640A MX PA01010640 A MXPA01010640 A MX PA01010640A MX PA01010640 A MXPA01010640 A MX PA01010640A MX PA01010640 A MXPA01010640 A MX PA01010640A MX PA01010640 A MXPA01010640 A MX PA01010640A
Authority
MX
Mexico
Prior art keywords
measurement
molecular interactions
affinity
binding partners
dependent
Prior art date
Application number
MXPA01010640A
Other languages
English (en)
Inventor
David Klenerman
Original Assignee
Akubio Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akubio Ltd filed Critical Akubio Ltd
Publication of MXPA01010640A publication Critical patent/MXPA01010640A/es

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438Electrodes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/808Optical sensing apparatus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/805Optical property

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
MXPA01010640A 1999-04-22 2000-04-25 Medicion y uso de interacciones moleculares. MXPA01010640A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9909308.0A GB9909308D0 (en) 1999-04-22 1999-04-22 Measurement and use of molecular interactions
PCT/GB2000/001587 WO2001002857A1 (en) 1999-04-22 2000-04-25 Measurement and use of molecular interactions

Publications (1)

Publication Number Publication Date
MXPA01010640A true MXPA01010640A (es) 2003-08-20

Family

ID=10852091

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA01010640A MXPA01010640A (es) 1999-04-22 2000-04-25 Medicion y uso de interacciones moleculares.

Country Status (23)

Country Link
US (2) US6589727B1 (es)
EP (1) EP1171769B1 (es)
JP (1) JP4493892B2 (es)
KR (1) KR20020022648A (es)
CN (1) CN1142435C (es)
AT (1) ATE278191T1 (es)
AU (1) AU755958B2 (es)
BR (1) BR0009865A (es)
CA (1) CA2369794A1 (es)
CZ (1) CZ20013633A3 (es)
DE (1) DE60014348T8 (es)
ES (1) ES2226825T3 (es)
GB (1) GB9909308D0 (es)
HK (1) HK1041920B (es)
HU (1) HUP0200787A2 (es)
IL (2) IL145754A0 (es)
MX (1) MXPA01010640A (es)
NO (1) NO20015096L (es)
PL (1) PL354354A1 (es)
RU (1) RU2223500C2 (es)
UA (1) UA57876C2 (es)
WO (1) WO2001002857A1 (es)
ZA (1) ZA200108562B (es)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4773019B2 (ja) 1999-11-08 2011-09-14 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド 薬物の服薬遵守を監視するためのマーカー検出の方法および器具
US20050233459A1 (en) * 2003-11-26 2005-10-20 Melker Richard J Marker detection method and apparatus to monitor drug compliance
US7104963B2 (en) * 2002-01-22 2006-09-12 University Of Florida Research Foundation, Inc. Method and apparatus for monitoring intravenous (IV) drug concentration using exhaled breath
US6981947B2 (en) * 2002-01-22 2006-01-03 University Of Florida Research Foundation, Inc. Method and apparatus for monitoring respiratory gases during anesthesia
US20050054942A1 (en) * 2002-01-22 2005-03-10 Melker Richard J. System and method for therapeutic drug monitoring
AU2002310031A1 (en) * 2001-05-23 2002-12-03 University Of Florida Method and apparatus for detecting illicit substances
DE10126798A1 (de) * 2001-06-01 2002-12-19 Nanotype Gmbh Verfahren zur Bestimmung einer Probe
US6865949B2 (en) 2003-01-31 2005-03-15 Hewlett-Packard Development Company, L.P. Transducer-based sensor system
US20070167853A1 (en) 2002-01-22 2007-07-19 Melker Richard J System and method for monitoring health using exhaled breath
WO2004034883A2 (en) * 2002-10-15 2004-04-29 Medtronic Inc. Synchronization and calibration of clocks for a medical device and calibrated clock
US7135806B2 (en) 2002-10-31 2006-11-14 Hewlett-Packard Development Company, L.P. Transducer-based sensor system with multiple drive signal variants
EP1588168B1 (de) * 2003-01-26 2009-07-08 Eberhard-Karls-Universität Tübingen Universitätsklinikum Verfahren zum separieren und nachweisen von zumindest einem analyten in biologischen matrizes
WO2005012909A1 (en) * 2003-03-04 2005-02-10 Auburn University Methods of forming monolayers of phage-derived products and uses thereof
EP1616171A1 (en) 2003-04-17 2006-01-18 Akubio Limited Improvements to rupture event sensors
US7117743B2 (en) 2003-07-31 2006-10-10 Hewlett-Packard Development Company, L.P. Multiple-transducer sensor system and method with selective activation and isolation of individual transducers
US6978656B2 (en) 2003-10-31 2005-12-27 Hewlett-Packard Development Company, L.P. Transducer-based sensor system and method
NZ528338A (en) * 2004-03-19 2006-10-27 Ind Res Ltd Biosensors for detecting bond rupture
US20050226773A1 (en) * 2004-04-01 2005-10-13 Honeywell International, Inc. Multiple modes acoustic wave sensor
US7539459B2 (en) * 2004-04-02 2009-05-26 Edwards Vacuum, Inc. Active noise cancellation system, arrangement, and method
US7497133B2 (en) 2004-05-24 2009-03-03 Drexel University All electric piezoelectric finger sensor (PEFS) for soft material stiffness measurement
WO2006083288A1 (en) * 2004-06-04 2006-08-10 University Of Northern Iowa Research Foundation Bacteriophages that infect bacillus bacteria (anthrax)
US7648844B2 (en) 2005-05-02 2010-01-19 Bioscale, Inc. Method and apparatus for detection of analyte using an acoustic device
US7749445B2 (en) 2005-05-02 2010-07-06 Bioscale, Inc. Method and apparatus for analyzing bioprocess fluids
EP1940355B1 (en) 2005-09-30 2012-12-19 Auburn University Targeted drug delivery nanocarrier comprising a targeting landscape phage protein assembly
US8227261B2 (en) * 2005-11-23 2012-07-24 Bioscale, Inc. Methods and apparatus for assay measurements
US7942056B2 (en) * 2006-01-23 2011-05-17 Drexel University Self-exciting, self-sensing piezoelectric cantilever sensor
US8171795B1 (en) 2006-01-23 2012-05-08 Drexel University Self-exciting, self-sensing piezoelectric cantilever sensor for detection of airborne analytes directly in air
WO2007133619A1 (en) * 2006-05-10 2007-11-22 Drexel University Molecular control of surface coverage
GB0609382D0 (en) * 2006-05-11 2006-06-21 Univ Cambridge Tech Acoustic wave transducer substrate and measurements using the same
DE102006034842A1 (de) * 2006-07-27 2008-02-07 Siemens Ag Fluidsensor
US7914460B2 (en) * 2006-08-15 2011-03-29 University Of Florida Research Foundation, Inc. Condensate glucose analyzer
US8481335B2 (en) * 2006-11-27 2013-07-09 Drexel University Specificity and sensitivity enhancement in cantilever sensing
US7992431B2 (en) * 2006-11-28 2011-08-09 Drexel University Piezoelectric microcantilevers and uses in atomic force microscopy
US8927259B2 (en) * 2006-11-28 2015-01-06 Drexel University Piezoelectric microcantilever sensors for biosensing
CA2677196A1 (en) * 2007-02-01 2008-09-12 Drexel University A hand-held phase-shift detector for sensor applications
US8512947B2 (en) * 2007-02-16 2013-08-20 Drexel University Detection of nucleic acids using a cantilever sensor
WO2008101199A1 (en) 2007-02-16 2008-08-21 Drexel University Enhanced sensitivity of a cantilever sensor via specific bindings
WO2009035732A2 (en) * 2007-05-30 2009-03-19 Drexel University Detection and quantification of biomarkers via a piezoelectric cantilever sensor
WO2009033056A1 (en) * 2007-09-06 2009-03-12 Bioscale, Inc. Reusable detection surfaces and methods of using same
WO2009079154A2 (en) 2007-11-23 2009-06-25 Drexel University Lead-free piezoelectric ceramic films and a method for making thereof
RU2350957C1 (ru) * 2007-12-28 2009-03-27 Институт аналитического приборостроения Российской академии наук Устройство для иммунологических исследований биологических жидкостей
US8236508B2 (en) * 2008-01-29 2012-08-07 Drexel University Detecting and measuring live pathogens utilizing a mass detection device
US8741663B2 (en) 2008-03-11 2014-06-03 Drexel University Enhanced detection sensitivity with piezoelectric sensors
EP2281192A4 (en) 2008-05-16 2014-02-05 Univ Drexel SYSTEM AND METHOD FOR EVALUATING TISSUE
GB2473635A (en) * 2009-09-18 2011-03-23 Cambridge Entpr Ltd Detecting concentration of target species
US20110086368A1 (en) * 2009-10-08 2011-04-14 Drexel University Method for immune response detection
US8722427B2 (en) * 2009-10-08 2014-05-13 Drexel University Determination of dissociation constants using piezoelectric microcantilevers
US9176152B2 (en) 2010-05-25 2015-11-03 Arryx, Inc Methods and apparatuses for detection of positional freedom of particles in biological and chemical analyses and applications in immunodiagnostics
GB201020237D0 (en) * 2010-11-30 2011-01-12 Cambridge Entpr Ltd Method and apparatus for characterising molecules
NL2017705B1 (en) * 2016-11-02 2018-05-18 Lumicks Tech B V Method and system for studying biological cells
US10191036B1 (en) * 2018-03-22 2019-01-29 NUB4U, Inc. System for detecting and removing biological analytes in fluids
RU184943U1 (ru) * 2018-04-09 2018-11-15 Федеральное государственное бюджетное учреждение науки Институт физики полупроводников им. А.В. Ржанова Сибирского отделения Российской академии наук Устройство для проведения высокоспецифичной детекции биомаркеров на кварцевом резонаторе
NL2026393B1 (en) * 2020-09-01 2022-05-04 Lumicks Ca Holding B V Sorting of cellular bodies based on force spectroscopy

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4242096A (en) * 1977-11-14 1980-12-30 Minnesota Mining And Manufacturing Company Immunoassay for antigens
US4314821A (en) * 1979-04-09 1982-02-09 Minnesota Mining And Manufacturing Company Sandwich immunoassay using piezoelectric oscillator
US4236893A (en) * 1979-04-09 1980-12-02 Minnesota Mining And Manufacturing Company Method for the assay of classes of antigen-specific antibodies
US4735906A (en) * 1984-11-28 1988-04-05 Texas A&M University Sensor having piezoelectric crystal for microgravimetric immunoassays
US4999284A (en) * 1988-04-06 1991-03-12 E. I. Du Pont De Nemours And Company Enzymatically amplified piezoelectric specific binding assay
US5501986A (en) * 1988-04-06 1996-03-26 E. I. Du Pont De Nemours And Company Piezoelectric specific binding assay with mass amplified reagents
US5552274A (en) * 1992-09-07 1996-09-03 Terumo Kabushiki Kaisha Method for detecting target sequences by oscillation frequency
IL114692A (en) * 1995-07-21 1999-10-28 Yissum Res Dev Co Determination of an analyte in a liquid medium
US5814525A (en) * 1996-01-25 1998-09-29 Sandia Corporation Piezoelectric biosensor with a ladder polymer substrate coating
IL120445A0 (en) 1997-03-13 1997-07-13 Yissum Res Dev Co Biosensor for cells
GB9706991D0 (en) 1997-04-05 1997-05-21 Univ Heriot Watt Clathrate hydrate dissociation point detection and measurement
US6086821A (en) 1999-03-29 2000-07-11 The United States Of America As Represented By The Secretary Of The Navy Ultrasonic force differentiation assay
US6308553B1 (en) * 1999-06-04 2001-10-30 Honeywell International Inc Self-normalizing flow sensor and method for the same

Also Published As

Publication number Publication date
NO20015096D0 (no) 2001-10-19
HK1041920B (zh) 2005-03-18
AU4420300A (en) 2001-01-22
ES2226825T3 (es) 2005-04-01
GB9909308D0 (en) 1999-06-16
EP1171769A1 (en) 2002-01-16
US6589727B1 (en) 2003-07-08
WO2001002857A1 (en) 2001-01-11
IL145754A (en) 2006-09-05
CN1347500A (zh) 2002-05-01
DE60014348T2 (de) 2006-02-16
ZA200108562B (en) 2002-09-11
ATE278191T1 (de) 2004-10-15
JP2003503735A (ja) 2003-01-28
HK1041920A1 (en) 2002-07-26
EP1171769B1 (en) 2004-09-29
AU755958B2 (en) 2003-01-02
RU2223500C2 (ru) 2004-02-10
CA2369794A1 (en) 2001-01-11
IL145754A0 (en) 2002-07-25
NO20015096L (no) 2001-12-14
KR20020022648A (ko) 2002-03-27
DE60014348T8 (de) 2006-04-27
DE60014348D1 (de) 2004-11-04
UA57876C2 (uk) 2003-07-15
BR0009865A (pt) 2002-03-19
PL354354A1 (en) 2004-01-12
CZ20013633A3 (cs) 2002-06-12
CN1142435C (zh) 2004-03-17
US20030194697A1 (en) 2003-10-16
JP4493892B2 (ja) 2010-06-30
US7195909B2 (en) 2007-03-27
HUP0200787A2 (hu) 2002-07-29

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