BR0009865A - Medição e uso de interações moleculares - Google Patents

Medição e uso de interações moleculares

Info

Publication number
BR0009865A
BR0009865A BR0009865-5A BR0009865A BR0009865A BR 0009865 A BR0009865 A BR 0009865A BR 0009865 A BR0009865 A BR 0009865A BR 0009865 A BR0009865 A BR 0009865A
Authority
BR
Brazil
Prior art keywords
affinity
partners
measurement
molecular interactions
liaison
Prior art date
Application number
BR0009865-5A
Other languages
English (en)
Inventor
David Klenerman
Victor Petrovich Ostanin
Fedor Nikolaievich Dultsev
Original Assignee
Akubio Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akubio Ltd filed Critical Akubio Ltd
Publication of BR0009865A publication Critical patent/BR0009865A/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Patente de Invenção: "MEDIçãO E USO DE INTERAçõES MOLECULARES". Um processo para determinação da afinidade entre parceiros de ligação, ou de uma propriedade de um dos parceiros de ligação dependente da afinidade, compreende as etapas de: (i) colocação em contato dos parceiros de ligação, um dos quais está imobilizado em uma superfície; (ii) oscilação da superfície à amplitude crescente e (iii) detecção de um evento de dissociação. Um processo análogo pode ser usado para separar um análito alvo de uma composição. Aparelho para a determinação da afinidade entre parceiros de ligação compreende: uma superfície (10) tendo um parceiro de ligação (16) imobilizado sobre ela; dispositivo para oscilar a superfície em amplitude crescente e dispositivo (14, 15) para detectar um evento de dissociação.
BR0009865-5A 1999-04-22 2000-04-25 Medição e uso de interações moleculares BR0009865A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9909308.0A GB9909308D0 (en) 1999-04-22 1999-04-22 Measurement and use of molecular interactions
PCT/GB2000/001587 WO2001002857A1 (en) 1999-04-22 2000-04-25 Measurement and use of molecular interactions

Publications (1)

Publication Number Publication Date
BR0009865A true BR0009865A (pt) 2002-03-19

Family

ID=10852091

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0009865-5A BR0009865A (pt) 1999-04-22 2000-04-25 Medição e uso de interações moleculares

Country Status (23)

Country Link
US (2) US6589727B1 (pt)
EP (1) EP1171769B1 (pt)
JP (1) JP4493892B2 (pt)
KR (1) KR20020022648A (pt)
CN (1) CN1142435C (pt)
AT (1) ATE278191T1 (pt)
AU (1) AU755958B2 (pt)
BR (1) BR0009865A (pt)
CA (1) CA2369794A1 (pt)
CZ (1) CZ20013633A3 (pt)
DE (1) DE60014348T8 (pt)
ES (1) ES2226825T3 (pt)
GB (1) GB9909308D0 (pt)
HK (1) HK1041920B (pt)
HU (1) HUP0200787A2 (pt)
IL (2) IL145754A0 (pt)
MX (1) MXPA01010640A (pt)
NO (1) NO20015096L (pt)
PL (1) PL354354A1 (pt)
RU (1) RU2223500C2 (pt)
UA (1) UA57876C2 (pt)
WO (1) WO2001002857A1 (pt)
ZA (1) ZA200108562B (pt)

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AU2002310031A1 (en) * 2001-05-23 2002-12-03 University Of Florida Method and apparatus for detecting illicit substances
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US20070167853A1 (en) 2002-01-22 2007-07-19 Melker Richard J System and method for monitoring health using exhaled breath
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US7117743B2 (en) 2003-07-31 2006-10-10 Hewlett-Packard Development Company, L.P. Multiple-transducer sensor system and method with selective activation and isolation of individual transducers
US6978656B2 (en) * 2003-10-31 2005-12-27 Hewlett-Packard Development Company, L.P. Transducer-based sensor system and method
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US20050226773A1 (en) * 2004-04-01 2005-10-13 Honeywell International, Inc. Multiple modes acoustic wave sensor
US7539459B2 (en) * 2004-04-02 2009-05-26 Edwards Vacuum, Inc. Active noise cancellation system, arrangement, and method
US7497133B2 (en) 2004-05-24 2009-03-03 Drexel University All electric piezoelectric finger sensor (PEFS) for soft material stiffness measurement
US20080193418A1 (en) * 2004-06-04 2008-08-14 University Of Northern Iowa Research Foundation Bacteriophages that Infect Bacillus Bacteria (Anthrax)
US7648844B2 (en) 2005-05-02 2010-01-19 Bioscale, Inc. Method and apparatus for detection of analyte using an acoustic device
US7749445B2 (en) 2005-05-02 2010-07-06 Bioscale, Inc. Method and apparatus for analyzing bioprocess fluids
EP1940355B1 (en) 2005-09-30 2012-12-19 Auburn University Targeted drug delivery nanocarrier comprising a targeting landscape phage protein assembly
US8227261B2 (en) * 2005-11-23 2012-07-24 Bioscale, Inc. Methods and apparatus for assay measurements
AU2007208310B2 (en) * 2006-01-23 2012-05-31 Drexel University Self-exciting, self-sensing piezoelectric cantilever sensor
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GB0609382D0 (en) * 2006-05-11 2006-06-21 Univ Cambridge Tech Acoustic wave transducer substrate and measurements using the same
DE102006034842A1 (de) * 2006-07-27 2008-02-07 Siemens Ag Fluidsensor
US7914460B2 (en) * 2006-08-15 2011-03-29 University Of Florida Research Foundation, Inc. Condensate glucose analyzer
US8481335B2 (en) * 2006-11-27 2013-07-09 Drexel University Specificity and sensitivity enhancement in cantilever sensing
US7992431B2 (en) * 2006-11-28 2011-08-09 Drexel University Piezoelectric microcantilevers and uses in atomic force microscopy
US8927259B2 (en) 2006-11-28 2015-01-06 Drexel University Piezoelectric microcantilever sensors for biosensing
EP2115448A4 (en) * 2007-02-01 2013-01-30 Univ Drexel PORTABLE PHASE SHIFT DETECTOR FOR SENSOR APPLICATIONS
US8512947B2 (en) * 2007-02-16 2013-08-20 Drexel University Detection of nucleic acids using a cantilever sensor
WO2008101199A1 (en) 2007-02-16 2008-08-21 Drexel University Enhanced sensitivity of a cantilever sensor via specific bindings
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WO2009079154A2 (en) 2007-11-23 2009-06-25 Drexel University Lead-free piezoelectric ceramic films and a method for making thereof
RU2350957C1 (ru) * 2007-12-28 2009-03-27 Институт аналитического приборостроения Российской академии наук Устройство для иммунологических исследований биологических жидкостей
US8236508B2 (en) * 2008-01-29 2012-08-07 Drexel University Detecting and measuring live pathogens utilizing a mass detection device
US8741663B2 (en) 2008-03-11 2014-06-03 Drexel University Enhanced detection sensitivity with piezoelectric sensors
WO2009140660A2 (en) * 2008-05-16 2009-11-19 Drexel University System and method for evaluating tissue
GB2473635A (en) * 2009-09-18 2011-03-23 Cambridge Entpr Ltd Detecting concentration of target species
US8722427B2 (en) * 2009-10-08 2014-05-13 Drexel University Determination of dissociation constants using piezoelectric microcantilevers
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JP2013531787A (ja) 2010-05-25 2013-08-08 アリックス インコーポレイテッド 粒子の運動度および／または細胞の分散を求めるためのホログラフィック変動顕微鏡装置および方法
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Also Published As

Publication number Publication date
DE60014348T8 (de) 2006-04-27
KR20020022648A (ko) 2002-03-27
ES2226825T3 (es) 2005-04-01
EP1171769A1 (en) 2002-01-16
ZA200108562B (en) 2002-09-11
HK1041920A1 (en) 2002-07-26
EP1171769B1 (en) 2004-09-29
RU2223500C2 (ru) 2004-02-10
DE60014348D1 (de) 2004-11-04
CN1347500A (zh) 2002-05-01
DE60014348T2 (de) 2006-02-16
MXPA01010640A (es) 2003-08-20
JP4493892B2 (ja) 2010-06-30
US20030194697A1 (en) 2003-10-16
AU4420300A (en) 2001-01-22
AU755958B2 (en) 2003-01-02
US6589727B1 (en) 2003-07-08
HK1041920B (zh) 2005-03-18
IL145754A (en) 2006-09-05
IL145754A0 (en) 2002-07-25
PL354354A1 (en) 2004-01-12
ATE278191T1 (de) 2004-10-15
CA2369794A1 (en) 2001-01-11
US7195909B2 (en) 2007-03-27
UA57876C2 (uk) 2003-07-15
NO20015096L (no) 2001-12-14
CN1142435C (zh) 2004-03-17
NO20015096D0 (no) 2001-10-19
GB9909308D0 (en) 1999-06-16
CZ20013633A3 (cs) 2002-06-12
JP2003503735A (ja) 2003-01-28
WO2001002857A1 (en) 2001-01-11
HUP0200787A2 (hu) 2002-07-29

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A E 9A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 NA RPI2003 DE 26/05/2009.