MXPA01010127A - Inhibidores de la caspasa y el uso de los mismos. - Google Patents
Inhibidores de la caspasa y el uso de los mismos.Info
- Publication number
- MXPA01010127A MXPA01010127A MXPA01010127A MXPA01010127A MXPA01010127A MX PA01010127 A MXPA01010127 A MX PA01010127A MX PA01010127 A MXPA01010127 A MX PA01010127A MX PA01010127 A MXPA01010127 A MX PA01010127A MX PA01010127 A MXPA01010127 A MX PA01010127A
- Authority
- MX
- Mexico
- Prior art keywords
- compound
- asp
- fmk
- val
- cell death
- Prior art date
Links
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Classifications
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- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/66—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Hospice & Palliative Care (AREA)
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- Urology & Nephrology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12854599P | 1999-04-09 | 1999-04-09 | |
| US15837099P | 1999-10-12 | 1999-10-12 | |
| PCT/US2000/009319 WO2000061542A1 (en) | 1999-04-09 | 2000-04-07 | Caspase inhibitors and the use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA01010127A true MXPA01010127A (es) | 2002-08-20 |
Family
ID=26826691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA01010127A MXPA01010127A (es) | 1999-04-09 | 2000-04-07 | Inhibidores de la caspasa y el uso de los mismos. |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US6355618B1 (enExample) |
| EP (1) | EP1177168B1 (enExample) |
| JP (1) | JP2002541237A (enExample) |
| KR (1) | KR20020005665A (enExample) |
| CN (1) | CN1176941C (enExample) |
| AT (1) | ATE363465T1 (enExample) |
| AU (1) | AU4213500A (enExample) |
| BR (1) | BR0009610A (enExample) |
| CA (1) | CA2369619A1 (enExample) |
| DE (1) | DE60035037T2 (enExample) |
| MX (1) | MXPA01010127A (enExample) |
| WO (1) | WO2000061542A1 (enExample) |
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| JP6836996B2 (ja) * | 2015-02-25 | 2021-03-03 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 新しいトリフルオロメチルプロパンアミド誘導体 |
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-
2000
- 2000-04-07 WO PCT/US2000/009319 patent/WO2000061542A1/en not_active Ceased
- 2000-04-07 EP EP00921874A patent/EP1177168B1/en not_active Expired - Lifetime
- 2000-04-07 JP JP2000610819A patent/JP2002541237A/ja active Pending
- 2000-04-07 US US09/545,565 patent/US6355618B1/en not_active Expired - Fee Related
- 2000-04-07 DE DE60035037T patent/DE60035037T2/de not_active Expired - Fee Related
- 2000-04-07 MX MXPA01010127A patent/MXPA01010127A/es unknown
- 2000-04-07 AT AT00921874T patent/ATE363465T1/de not_active IP Right Cessation
- 2000-04-07 KR KR1020017012879A patent/KR20020005665A/ko not_active Withdrawn
- 2000-04-07 AU AU42135/00A patent/AU4213500A/en not_active Abandoned
- 2000-04-07 CN CNB008070202A patent/CN1176941C/zh not_active Expired - Fee Related
- 2000-04-07 BR BR0009610-5A patent/BR0009610A/pt not_active Application Discontinuation
- 2000-04-07 CA CA002369619A patent/CA2369619A1/en not_active Abandoned
-
2001
- 2001-11-14 US US09/987,417 patent/US6716818B2/en not_active Expired - Fee Related
-
2003
- 2003-11-26 US US10/721,338 patent/US20040116355A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US6716818B2 (en) | 2004-04-06 |
| WO2000061542A1 (en) | 2000-10-19 |
| DE60035037T2 (de) | 2008-01-31 |
| DE60035037D1 (de) | 2007-07-12 |
| CA2369619A1 (en) | 2000-10-19 |
| EP1177168A4 (en) | 2003-06-25 |
| EP1177168B1 (en) | 2007-05-30 |
| JP2002541237A (ja) | 2002-12-03 |
| CN1349496A (zh) | 2002-05-15 |
| AU4213500A (en) | 2000-11-14 |
| EP1177168A1 (en) | 2002-02-06 |
| US6355618B1 (en) | 2002-03-12 |
| ATE363465T1 (de) | 2007-06-15 |
| CN1176941C (zh) | 2004-11-24 |
| KR20020005665A (ko) | 2002-01-17 |
| BR0009610A (pt) | 2002-02-13 |
| US20020058631A1 (en) | 2002-05-16 |
| US20040116355A1 (en) | 2004-06-17 |
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