MXPA01007033A - Heterociclos funcionalizados como moduladores de receptores de quimiocinas. - Google Patents
Heterociclos funcionalizados como moduladores de receptores de quimiocinas.Info
- Publication number
- MXPA01007033A MXPA01007033A MXPA01007033A MXPA01007033A MXPA01007033A MX PA01007033 A MXPA01007033 A MX PA01007033A MX PA01007033 A MXPA01007033 A MX PA01007033A MX PA01007033 A MXPA01007033 A MX PA01007033A MX PA01007033 A MXPA01007033 A MX PA01007033A
- Authority
- MX
- Mexico
- Prior art keywords
- chemokine receptor
- receptor modulators
- functionalized heterocycles
- heterocycles
- functionalized
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11565499P | 1999-01-13 | 1999-01-13 | |
PCT/US1999/030434 WO2000042045A2 (en) | 1999-01-13 | 1999-12-20 | Functionalized heterocycles as chemokine receptor modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA01007033A true MXPA01007033A (es) | 2003-07-21 |
Family
ID=22362668
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA01007033A MXPA01007033A (es) | 1999-01-13 | 1999-12-20 | Heterociclos funcionalizados como moduladores de receptores de quimiocinas. |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP1144415A2 (xx) |
JP (1) | JP2002534526A (xx) |
KR (1) | KR20010086166A (xx) |
CN (1) | CN1344270A (xx) |
AP (1) | AP2001002228A0 (xx) |
AU (1) | AU1940900A (xx) |
BR (1) | BR9916905A (xx) |
CA (1) | CA2372197A1 (xx) |
CZ (1) | CZ20012502A3 (xx) |
EA (1) | EA200100774A1 (xx) |
HK (1) | HK1044539A1 (xx) |
HU (1) | HUP0202932A3 (xx) |
IL (1) | IL144289A0 (xx) |
MX (1) | MXPA01007033A (xx) |
NO (1) | NO20013456L (xx) |
OA (1) | OA11820A (xx) |
PL (1) | PL349348A1 (xx) |
SK (1) | SK9972001A3 (xx) |
WO (1) | WO2000042045A2 (xx) |
ZA (1) | ZA200106592B (xx) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6951848B2 (en) | 2001-03-12 | 2005-10-04 | Millennium Pharmaceuticals, Inc., | Functionalized heterocycles as modulators of chemokine receptor function and methods of use therefor |
JP2004532209A (ja) * | 2001-03-29 | 2004-10-21 | イーライ・リリー・アンド・カンパニー | 5−ht6受容体の拮抗薬としてのn−(2−アリールエチル)ベンジルアミン |
WO2003035650A1 (fr) * | 2001-09-25 | 2003-05-01 | Takeda Chemical Industries, Ltd. | Inhibiteur d'entree |
EP1604981A4 (en) | 2003-03-14 | 2008-12-24 | Ono Pharmaceutical Co | NITROGENIC HETEROCYCLIC DERIVATIVES AND MEDICAMENTS CONTAINING THEM AS AN ACTIVE SUBSTANCE |
EP2364982A1 (en) | 2003-04-18 | 2011-09-14 | ONO Pharmaceutical Co., Ltd. | Spiro-piperidine compounds as chemokine receptor antagonists and medicinal use thereof |
TWI400232B (zh) | 2004-09-13 | 2013-07-01 | Ono Pharmaceutical Co | 含氮雜環衍生物及以該含氮雜環衍生物為有效成分之藥劑 |
JPWO2006129679A1 (ja) | 2005-05-31 | 2009-01-08 | 小野薬品工業株式会社 | スピロピペリジン化合物およびその医薬用途 |
EP1934219A1 (en) | 2005-09-16 | 2008-06-25 | Ranbaxy Laboratories Limited | Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors |
JP5251127B2 (ja) | 2005-10-28 | 2013-07-31 | 小野薬品工業株式会社 | 塩基性基を含有する化合物およびその用途 |
EP1961744B1 (en) | 2005-11-18 | 2013-04-17 | Ono Pharmaceutical Co., Ltd. | Basic group-containing compound and use thereof |
KR20080102181A (ko) * | 2006-02-15 | 2008-11-24 | 알러간, 인코포레이티드 | 스핑고신-1-포스페이트 (에스1피) 수용체 길항제 생물학적 활성을 갖는 아릴 또는 헤테로아릴기를 포함하는 인돌-3-카르보실산 아미드, 에스테르, 티오아미드 및 티올 에스테르 화합물 |
CN101460458A (zh) | 2006-02-15 | 2009-06-17 | 阿勒根公司 | 具有1-磷酸-鞘氨醇(s1p)受体拮抗剂生物活性的带芳基或者杂芳基基团的吲哚-3-羧酸的酰胺、酯、硫代酰胺和硫羟酸酯化合物 |
EP1995246A4 (en) | 2006-03-10 | 2010-11-17 | Ono Pharmaceutical Co | NITROGENATED HETEROCYCLIC DERIVATIVE AND MEDICAMENT WITH DERIVATIVE ACTIVE SUBSTANCE |
WO2007132846A1 (ja) | 2006-05-16 | 2007-11-22 | Ono Pharmaceutical Co., Ltd. | 保護されていてもよい酸性基を含有する化合物およびその用途 |
EA016633B1 (ru) * | 2006-05-23 | 2012-06-29 | Общество С Ограниченной Ответственностью "Инновационная Фармацевтика" | Замещенные индолы, способ их получения и применения |
WO2008016006A1 (en) | 2006-07-31 | 2008-02-07 | Ono Pharmaceutical Co., Ltd. | Compound having cyclic group bound thereto through spiro binding and use thereof |
AU2008206495A1 (en) * | 2007-01-11 | 2008-07-24 | Allergan, Inc. | 6-substituted indole-3-carboxylic acid amide compounds having Sphingosine-1-Phosphate (S1P) receptor antagonist biological activity |
US8524917B2 (en) | 2007-01-11 | 2013-09-03 | Allergan, Inc. | 6-substituted indole-3-carboxylic acid amide compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity |
WO2010129351A1 (en) | 2009-04-28 | 2010-11-11 | Schepens Eye Research Institute | Method to identify and treat age-related macular degeneration |
WO2011143430A1 (en) | 2010-05-12 | 2011-11-17 | Abbott Laboratories | Indazole inhibitors of kinase |
US20140271680A1 (en) | 2011-08-12 | 2014-09-18 | Universite Paris-Est Creteil Val De Marne | Methods and pharmaceutical compositions for treatment of pulmonary hypertension |
JO3459B1 (ar) | 2012-09-09 | 2020-07-05 | H Lundbeck As | تركيبات صيدلانية لعلاج مرض الزهايمر |
CN104193669B (zh) * | 2014-08-01 | 2016-12-07 | 大连理工大学 | 一类阿比朵尔类似物或其盐、其制备方法及应用 |
WO2016112088A1 (en) * | 2015-01-06 | 2016-07-14 | Spero Therapeutics, Inc. | Aryloxyacetylindoles and analogs as antibiotic tolerance inhibitors |
CN110256324A (zh) * | 2019-06-13 | 2019-09-20 | 苏州莱安医药化学技术有限公司 | 一种2-甲基-5-羟基吲哚的制备方法 |
US11629196B2 (en) | 2020-04-27 | 2023-04-18 | Incelldx, Inc. | Method of treating SARS-CoV-2-associated hypercytokinemia by administering a human monoclonal antibody (PRO-140) that inhibits CCR5/CCL5 binding interactions |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3549641A (en) * | 1966-06-28 | 1970-12-22 | Warner Lambert Pharmaceutical | Pyrano pyridines and process for their production |
US3518258A (en) * | 1967-05-09 | 1970-06-30 | Warner Lambert Pharmaceutical | Pyrano(3,2-i)quinolizine and process for the production |
US3565903A (en) * | 1967-11-24 | 1971-02-23 | Warner Lambert Pharmaceutical | Pyrano(2,3-b)quinolines and process for their production |
US5635510A (en) * | 1993-05-06 | 1997-06-03 | Merrell Pharmaceuticals Inc. | Substituted pyrrolidin-3-yl-alkyl-piperidines |
HRP960352A2 (en) * | 1996-07-26 | 1998-08-31 | Pliva Pharm & Chem Works | Novel coumarin quinoline carboxylic acids |
EP0966443B1 (en) * | 1997-02-26 | 2009-01-28 | Pfizer Inc. | Heteroaryl-hexanoic acid amide derivatives, their preparation and their use as selective inhibitors of mip-1-alpha binding to its ccr1 receptor |
WO1999038514A1 (en) * | 1998-02-02 | 1999-08-05 | Merck & Co., Inc. | Cyclic amine modulators of chemokine receptor activity |
-
1999
- 1999-12-20 AP APAP/P/2001/002228A patent/AP2001002228A0/en unknown
- 1999-12-20 MX MXPA01007033A patent/MXPA01007033A/es unknown
- 1999-12-20 SK SK997-2001A patent/SK9972001A3/sk unknown
- 1999-12-20 AU AU19409/00A patent/AU1940900A/en not_active Abandoned
- 1999-12-20 EA EA200100774A patent/EA200100774A1/ru unknown
- 1999-12-20 HU HU0202932A patent/HUP0202932A3/hu unknown
- 1999-12-20 EP EP99963110A patent/EP1144415A2/en not_active Withdrawn
- 1999-12-20 WO PCT/US1999/030434 patent/WO2000042045A2/en not_active Application Discontinuation
- 1999-12-20 BR BR9916905-3A patent/BR9916905A/pt not_active Application Discontinuation
- 1999-12-20 JP JP2000593612A patent/JP2002534526A/ja active Pending
- 1999-12-20 CA CA002372197A patent/CA2372197A1/en not_active Abandoned
- 1999-12-20 CZ CZ20012502A patent/CZ20012502A3/cs unknown
- 1999-12-20 IL IL14428999A patent/IL144289A0/xx unknown
- 1999-12-20 PL PL99349348A patent/PL349348A1/xx not_active Application Discontinuation
- 1999-12-20 KR KR1020017008905A patent/KR20010086166A/ko not_active Application Discontinuation
- 1999-12-20 CN CN99816475A patent/CN1344270A/zh active Pending
- 1999-12-20 OA OA1200100187A patent/OA11820A/en unknown
-
2001
- 2001-07-12 NO NO20013456A patent/NO20013456L/no not_active Application Discontinuation
- 2001-08-10 ZA ZA200106592A patent/ZA200106592B/en unknown
-
2002
- 2002-08-28 HK HK02106357.2A patent/HK1044539A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
SK9972001A3 (en) | 2002-03-05 |
CA2372197A1 (en) | 2000-07-20 |
BR9916905A (pt) | 2002-01-29 |
AP2001002228A0 (en) | 2001-09-30 |
OA11820A (en) | 2005-08-17 |
IL144289A0 (en) | 2002-05-23 |
ZA200106592B (en) | 2002-08-12 |
JP2002534526A (ja) | 2002-10-15 |
EP1144415A2 (en) | 2001-10-17 |
WO2000042045A2 (en) | 2000-07-20 |
HUP0202932A3 (en) | 2003-07-28 |
NO20013456L (no) | 2001-09-12 |
EA200100774A1 (ru) | 2002-02-28 |
HK1044539A1 (zh) | 2002-10-25 |
WO2000042045A3 (en) | 2000-11-09 |
HUP0202932A2 (hu) | 2002-12-28 |
CZ20012502A3 (cs) | 2002-03-13 |
AU1940900A (en) | 2000-08-01 |
KR20010086166A (ko) | 2001-09-08 |
PL349348A1 (en) | 2002-07-15 |
NO20013456D0 (no) | 2001-07-12 |
CN1344270A (zh) | 2002-04-10 |
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