HUP0202932A3 - Heterocyclic compounds and pharmaceutical compositions can be used as chemokine receptor modulators - Google Patents

Heterocyclic compounds and pharmaceutical compositions can be used as chemokine receptor modulators

Info

Publication number
HUP0202932A3
HUP0202932A3 HU0202932A HUP0202932A HUP0202932A3 HU P0202932 A3 HUP0202932 A3 HU P0202932A3 HU 0202932 A HU0202932 A HU 0202932A HU P0202932 A HUP0202932 A HU P0202932A HU P0202932 A3 HUP0202932 A3 HU P0202932A3
Authority
HU
Hungary
Prior art keywords
pharmaceutical compositions
heterocyclic compounds
chemokine receptor
receptor modulators
modulators
Prior art date
Application number
HU0202932A
Other languages
English (en)
Original Assignee
Millennium Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc
Publication of HUP0202932A2 publication Critical patent/HUP0202932A2/hu
Publication of HUP0202932A3 publication Critical patent/HUP0202932A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D455/00Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/02Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
HU0202932A 1999-01-13 1999-12-20 Heterocyclic compounds and pharmaceutical compositions can be used as chemokine receptor modulators HUP0202932A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11565499P 1999-01-13 1999-01-13
PCT/US1999/030434 WO2000042045A2 (en) 1999-01-13 1999-12-20 Functionalized heterocycles as chemokine receptor modulators

Publications (2)

Publication Number Publication Date
HUP0202932A2 HUP0202932A2 (hu) 2002-12-28
HUP0202932A3 true HUP0202932A3 (en) 2003-07-28

Family

ID=22362668

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0202932A HUP0202932A3 (en) 1999-01-13 1999-12-20 Heterocyclic compounds and pharmaceutical compositions can be used as chemokine receptor modulators

Country Status (20)

Country Link
EP (1) EP1144415A2 (hu)
JP (1) JP2002534526A (hu)
KR (1) KR20010086166A (hu)
CN (1) CN1344270A (hu)
AP (1) AP2001002228A0 (hu)
AU (1) AU1940900A (hu)
BR (1) BR9916905A (hu)
CA (1) CA2372197A1 (hu)
CZ (1) CZ20012502A3 (hu)
EA (1) EA200100774A1 (hu)
HK (1) HK1044539A1 (hu)
HU (1) HUP0202932A3 (hu)
IL (1) IL144289A0 (hu)
MX (1) MXPA01007033A (hu)
NO (1) NO20013456L (hu)
OA (1) OA11820A (hu)
PL (1) PL349348A1 (hu)
SK (1) SK9972001A3 (hu)
WO (1) WO2000042045A2 (hu)
ZA (1) ZA200106592B (hu)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002072549A1 (en) * 2001-03-12 2002-09-19 Millennium Pharmaceuticals, Inc. Functionalized heterocycles as modulators of chemokine receptor function and methods of use therefor
AU2002303094B2 (en) * 2001-03-29 2006-11-23 Eli Lilly And Company N-(2-arylethyl)benzylamines as antagonists of the 5-HT6 receptor
WO2003035650A1 (fr) * 2001-09-25 2003-05-01 Takeda Chemical Industries, Ltd. Inhibiteur d'entree
BRPI0408332A (pt) 2003-03-14 2006-03-21 Ono Pharmaceutical Co derivados heterocìclicos contendo nitrogênio e medicamentos contendo os mesmos como ingrediente ativo
US7498323B2 (en) 2003-04-18 2009-03-03 Ono Pharmaceuticals Co., Ltd. Spiro-piperidine compounds and medicinal use thereof
CN101775013A (zh) 2004-09-13 2010-07-14 小野药品工业株式会社 含氮杂环衍生物及含有其作为活性成分的药物
WO2006129679A1 (ja) 2005-05-31 2006-12-07 Ono Pharmaceutical Co., Ltd. スピロピペリジン化合物およびその医薬用途
US7915286B2 (en) 2005-09-16 2011-03-29 Ranbaxy Laboratories Limited Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors
PL1942108T3 (pl) 2005-10-28 2014-03-31 Ono Pharmaceutical Co Związek zawierający grupę zasadową i jego zastosowanie
ES2407115T3 (es) 2005-11-18 2013-06-11 Ono Pharmaceutical Co., Ltd. Compuesto que contiene un grupo básico y uso del mismo
WO2007095561A2 (en) * 2006-02-15 2007-08-23 Allergan, Inc. Indole-3-carboxylic acid amide, ester, thioamide and thiol ester compounds bearing aryl or heteroaryl groups having sphingosine-1-phosphate (s1p) receptor antagonist biological activity
CN101460458A (zh) 2006-02-15 2009-06-17 阿勒根公司 具有1-磷酸-鞘氨醇(s1p)受体拮抗剂生物活性的带芳基或者杂芳基基团的吲哚-3-羧酸的酰胺、酯、硫代酰胺和硫羟酸酯化合物
WO2007105637A1 (ja) 2006-03-10 2007-09-20 Ono Pharmaceutical Co., Ltd. 含窒素複素環誘導体およびそれらを有効成分とする薬剤
JP5257068B2 (ja) 2006-05-16 2013-08-07 小野薬品工業株式会社 保護されていてもよい酸性基を含有する化合物およびその用途
EA016633B1 (ru) * 2006-05-23 2012-06-29 Общество С Ограниченной Ответственностью "Инновационная Фармацевтика" Замещенные индолы, способ их получения и применения
EP2055705A4 (en) 2006-07-31 2014-08-20 Ono Pharmaceutical Co COMPOUND WITH A CYCLIC GROUP BOUND BY A SPIRO BINDING THEREOF AND APPLY THEREOF
US8524917B2 (en) 2007-01-11 2013-09-03 Allergan, Inc. 6-substituted indole-3-carboxylic acid amide compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity
KR20090101307A (ko) * 2007-01-11 2009-09-24 알러간, 인코포레이티드 스핑고신-1-포스페이트(s1p) 수용체 길항제 생물학적 활성을 갖는 6-치환된 인돌-3-카르복실산 아미드 화합물
WO2010129351A1 (en) 2009-04-28 2010-11-11 Schepens Eye Research Institute Method to identify and treat age-related macular degeneration
EP2569301A1 (en) 2010-05-12 2013-03-20 Abbvie Inc. Indazole inhibitors of kinase
EP2741777B1 (en) 2011-08-12 2017-01-18 INSERM - Institut National de la Santé et de la Recherche Médicale Methods and pharmaceutical compositions for treatment of pulmonary hypertension
JO3459B1 (ar) 2012-09-09 2020-07-05 H Lundbeck As تركيبات صيدلانية لعلاج مرض الزهايمر
CN104193669B (zh) * 2014-08-01 2016-12-07 大连理工大学 一类阿比朵尔类似物或其盐、其制备方法及应用
WO2016112088A1 (en) * 2015-01-06 2016-07-14 Spero Therapeutics, Inc. Aryloxyacetylindoles and analogs as antibiotic tolerance inhibitors
CN110256324A (zh) * 2019-06-13 2019-09-20 苏州莱安医药化学技术有限公司 一种2-甲基-5-羟基吲哚的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3549641A (en) * 1966-06-28 1970-12-22 Warner Lambert Pharmaceutical Pyrano pyridines and process for their production
US3518258A (en) * 1967-05-09 1970-06-30 Warner Lambert Pharmaceutical Pyrano(3,2-i)quinolizine and process for the production
US3565903A (en) * 1967-11-24 1971-02-23 Warner Lambert Pharmaceutical Pyrano(2,3-b)quinolines and process for their production
US5635510A (en) * 1993-05-06 1997-06-03 Merrell Pharmaceuticals Inc. Substituted pyrrolidin-3-yl-alkyl-piperidines
HRP960352A2 (en) * 1996-07-26 1998-08-31 Pliva Pharm & Chem Works Novel coumarin quinoline carboxylic acids
TR199902056T2 (xx) * 1997-02-26 2000-01-21 Pfizer Inc. Heteroaril-Heksanoik asit amid t�revleri.
WO1999038514A1 (en) * 1998-02-02 1999-08-05 Merck & Co., Inc. Cyclic amine modulators of chemokine receptor activity

Also Published As

Publication number Publication date
AU1940900A (en) 2000-08-01
SK9972001A3 (en) 2002-03-05
EP1144415A2 (en) 2001-10-17
BR9916905A (pt) 2002-01-29
JP2002534526A (ja) 2002-10-15
CZ20012502A3 (cs) 2002-03-13
KR20010086166A (ko) 2001-09-08
HK1044539A1 (zh) 2002-10-25
NO20013456D0 (no) 2001-07-12
CN1344270A (zh) 2002-04-10
WO2000042045A3 (en) 2000-11-09
IL144289A0 (en) 2002-05-23
MXPA01007033A (es) 2003-07-21
AP2001002228A0 (en) 2001-09-30
EA200100774A1 (ru) 2002-02-28
WO2000042045A2 (en) 2000-07-20
HUP0202932A2 (hu) 2002-12-28
OA11820A (en) 2005-08-17
PL349348A1 (en) 2002-07-15
ZA200106592B (en) 2002-08-12
CA2372197A1 (en) 2000-07-20
NO20013456L (no) 2001-09-12

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