PL349348A1 - Functionalized heterocycles as chemokine receptor modulators - Google Patents
Functionalized heterocycles as chemokine receptor modulatorsInfo
- Publication number
- PL349348A1 PL349348A1 PL99349348A PL34934899A PL349348A1 PL 349348 A1 PL349348 A1 PL 349348A1 PL 99349348 A PL99349348 A PL 99349348A PL 34934899 A PL34934899 A PL 34934899A PL 349348 A1 PL349348 A1 PL 349348A1
- Authority
- PL
- Poland
- Prior art keywords
- chemokine receptor
- receptor modulators
- functionalized heterocycles
- heterocycles
- functionalized
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11565499P | 1999-01-13 | 1999-01-13 | |
| PCT/US1999/030434 WO2000042045A2 (en) | 1999-01-13 | 1999-12-20 | Functionalized heterocycles as chemokine receptor modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL349348A1 true PL349348A1 (en) | 2002-07-15 |
Family
ID=22362668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL99349348A PL349348A1 (en) | 1999-01-13 | 1999-12-20 | Functionalized heterocycles as chemokine receptor modulators |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP1144415A2 (en) |
| JP (1) | JP2002534526A (en) |
| KR (1) | KR20010086166A (en) |
| CN (1) | CN1344270A (en) |
| AP (1) | AP2001002228A0 (en) |
| AU (1) | AU1940900A (en) |
| BR (1) | BR9916905A (en) |
| CA (1) | CA2372197A1 (en) |
| CZ (1) | CZ20012502A3 (en) |
| EA (1) | EA200100774A1 (en) |
| HK (1) | HK1044539A1 (en) |
| HU (1) | HUP0202932A3 (en) |
| IL (1) | IL144289A0 (en) |
| MX (1) | MXPA01007033A (en) |
| NO (1) | NO20013456L (en) |
| OA (1) | OA11820A (en) |
| PL (1) | PL349348A1 (en) |
| SK (1) | SK9972001A3 (en) |
| WO (1) | WO2000042045A2 (en) |
| ZA (1) | ZA200106592B (en) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6951848B2 (en) | 2001-03-12 | 2005-10-04 | Millennium Pharmaceuticals, Inc., | Functionalized heterocycles as modulators of chemokine receptor function and methods of use therefor |
| JP2004532209A (en) * | 2001-03-29 | 2004-10-21 | イーライ・リリー・アンド・カンパニー | N- (2-arylethyl) benzylamines as 5-HT6 receptor antagonists |
| WO2003035650A1 (en) * | 2001-09-25 | 2003-05-01 | Takeda Chemical Industries, Ltd. | Entry inhibitor |
| EP1604981A4 (en) | 2003-03-14 | 2008-12-24 | Ono Pharmaceutical Co | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient |
| EP2364982A1 (en) | 2003-04-18 | 2011-09-14 | ONO Pharmaceutical Co., Ltd. | Spiro-piperidine compounds as chemokine receptor antagonists and medicinal use thereof |
| TWI400232B (en) | 2004-09-13 | 2013-07-01 | Ono Pharmaceutical Co | Nitrogen-containing heterocyclic compound and medicament containing the same as active ingredient |
| JPWO2006129679A1 (en) | 2005-05-31 | 2009-01-08 | 小野薬品工業株式会社 | Spiropiperidine compounds and pharmaceutical uses thereof |
| EP1934219A1 (en) | 2005-09-16 | 2008-06-25 | Ranbaxy Laboratories Limited | Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors |
| JP5251127B2 (en) | 2005-10-28 | 2013-07-31 | 小野薬品工業株式会社 | COMPOUND CONTAINING BASIC GROUP AND USE THEREOF |
| EP1961744B1 (en) | 2005-11-18 | 2013-04-17 | Ono Pharmaceutical Co., Ltd. | Basic group-containing compound and use thereof |
| KR20080102181A (en) * | 2006-02-15 | 2008-11-24 | 알러간, 인코포레이티드 | Indole-3-carboxylic acid amide, ester, thioamide and thiol ester compounds bearing aryl or heteroaryl groups having sphingosine-1-phosphate (s1p) receptor antagonist biological activity |
| CN101460458A (en) | 2006-02-15 | 2009-06-17 | 阿勒根公司 | Indole-3-carboxylic acid amide, ester, thioamide and thiol ester compounds bearing aryl or heteroaryl groups having sphingosine-1-phosphate (S1P) receptor antagonist biological activity |
| EP1995246A4 (en) | 2006-03-10 | 2010-11-17 | Ono Pharmaceutical Co | Nitrogenated heterocyclic derivative, and pharmaceutical agent comprising the derivative as active ingredient |
| WO2007132846A1 (en) | 2006-05-16 | 2007-11-22 | Ono Pharmaceutical Co., Ltd. | Compound having acidic group which may be protected, and use thereof |
| EA016633B1 (en) * | 2006-05-23 | 2012-06-29 | Общество С Ограниченной Ответственностью "Инновационная Фармацевтика" | Substituted indoles and a method for the production and use thereof |
| WO2008016006A1 (en) | 2006-07-31 | 2008-02-07 | Ono Pharmaceutical Co., Ltd. | Compound having cyclic group bound thereto through spiro binding and use thereof |
| AU2008206495A1 (en) * | 2007-01-11 | 2008-07-24 | Allergan, Inc. | 6-substituted indole-3-carboxylic acid amide compounds having Sphingosine-1-Phosphate (S1P) receptor antagonist biological activity |
| US8524917B2 (en) | 2007-01-11 | 2013-09-03 | Allergan, Inc. | 6-substituted indole-3-carboxylic acid amide compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity |
| WO2010129351A1 (en) | 2009-04-28 | 2010-11-11 | Schepens Eye Research Institute | Method to identify and treat age-related macular degeneration |
| WO2011143430A1 (en) | 2010-05-12 | 2011-11-17 | Abbott Laboratories | Indazole inhibitors of kinase |
| US20140271680A1 (en) | 2011-08-12 | 2014-09-18 | Universite Paris-Est Creteil Val De Marne | Methods and pharmaceutical compositions for treatment of pulmonary hypertension |
| JO3459B1 (en) | 2012-09-09 | 2020-07-05 | H Lundbeck As | Pharmaceutical compositions for treating alzheimer's disease |
| CN104193669B (en) * | 2014-08-01 | 2016-12-07 | 大连理工大学 | One class Abiduoer analog or its salt, its preparation method and application |
| WO2016112088A1 (en) * | 2015-01-06 | 2016-07-14 | Spero Therapeutics, Inc. | Aryloxyacetylindoles and analogs as antibiotic tolerance inhibitors |
| CN110256324A (en) * | 2019-06-13 | 2019-09-20 | 苏州莱安医药化学技术有限公司 | A kind of preparation method of 2- methyl -5-OHi |
| US11629196B2 (en) | 2020-04-27 | 2023-04-18 | Incelldx, Inc. | Method of treating SARS-CoV-2-associated hypercytokinemia by administering a human monoclonal antibody (PRO-140) that inhibits CCR5/CCL5 binding interactions |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3549641A (en) * | 1966-06-28 | 1970-12-22 | Warner Lambert Pharmaceutical | Pyrano pyridines and process for their production |
| US3518258A (en) * | 1967-05-09 | 1970-06-30 | Warner Lambert Pharmaceutical | Pyrano(3,2-i)quinolizine and process for the production |
| US3565903A (en) * | 1967-11-24 | 1971-02-23 | Warner Lambert Pharmaceutical | Pyrano(2,3-b)quinolines and process for their production |
| US5635510A (en) * | 1993-05-06 | 1997-06-03 | Merrell Pharmaceuticals Inc. | Substituted pyrrolidin-3-yl-alkyl-piperidines |
| HRP960352A2 (en) * | 1996-07-26 | 1998-08-31 | Pliva Pharm & Chem Works | Novel coumarin quinoline carboxylic acids |
| EP0966443B1 (en) * | 1997-02-26 | 2009-01-28 | Pfizer Inc. | Heteroaryl-hexanoic acid amide derivatives, their preparation and their use as selective inhibitors of mip-1-alpha binding to its ccr1 receptor |
| WO1999038514A1 (en) * | 1998-02-02 | 1999-08-05 | Merck & Co., Inc. | Cyclic amine modulators of chemokine receptor activity |
-
1999
- 1999-12-20 AP APAP/P/2001/002228A patent/AP2001002228A0/en unknown
- 1999-12-20 MX MXPA01007033A patent/MXPA01007033A/en unknown
- 1999-12-20 SK SK997-2001A patent/SK9972001A3/en unknown
- 1999-12-20 AU AU19409/00A patent/AU1940900A/en not_active Abandoned
- 1999-12-20 EA EA200100774A patent/EA200100774A1/en unknown
- 1999-12-20 HU HU0202932A patent/HUP0202932A3/en unknown
- 1999-12-20 EP EP99963110A patent/EP1144415A2/en not_active Withdrawn
- 1999-12-20 WO PCT/US1999/030434 patent/WO2000042045A2/en not_active Application Discontinuation
- 1999-12-20 BR BR9916905-3A patent/BR9916905A/en not_active Application Discontinuation
- 1999-12-20 JP JP2000593612A patent/JP2002534526A/en active Pending
- 1999-12-20 CA CA002372197A patent/CA2372197A1/en not_active Abandoned
- 1999-12-20 CZ CZ20012502A patent/CZ20012502A3/en unknown
- 1999-12-20 IL IL14428999A patent/IL144289A0/en unknown
- 1999-12-20 PL PL99349348A patent/PL349348A1/en not_active Application Discontinuation
- 1999-12-20 KR KR1020017008905A patent/KR20010086166A/en not_active Application Discontinuation
- 1999-12-20 CN CN99816475A patent/CN1344270A/en active Pending
- 1999-12-20 OA OA1200100187A patent/OA11820A/en unknown
-
2001
- 2001-07-12 NO NO20013456A patent/NO20013456L/en not_active Application Discontinuation
- 2001-08-10 ZA ZA200106592A patent/ZA200106592B/en unknown
-
2002
- 2002-08-28 HK HK02106357.2A patent/HK1044539A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SK9972001A3 (en) | 2002-03-05 |
| CA2372197A1 (en) | 2000-07-20 |
| BR9916905A (en) | 2002-01-29 |
| AP2001002228A0 (en) | 2001-09-30 |
| OA11820A (en) | 2005-08-17 |
| IL144289A0 (en) | 2002-05-23 |
| ZA200106592B (en) | 2002-08-12 |
| MXPA01007033A (en) | 2003-07-21 |
| JP2002534526A (en) | 2002-10-15 |
| EP1144415A2 (en) | 2001-10-17 |
| WO2000042045A2 (en) | 2000-07-20 |
| HUP0202932A3 (en) | 2003-07-28 |
| NO20013456L (en) | 2001-09-12 |
| EA200100774A1 (en) | 2002-02-28 |
| HK1044539A1 (en) | 2002-10-25 |
| WO2000042045A3 (en) | 2000-11-09 |
| HUP0202932A2 (en) | 2002-12-28 |
| CZ20012502A3 (en) | 2002-03-13 |
| AU1940900A (en) | 2000-08-01 |
| KR20010086166A (en) | 2001-09-08 |
| NO20013456D0 (en) | 2001-07-12 |
| CN1344270A (en) | 2002-04-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL349348A1 (en) | Functionalized heterocycles as chemokine receptor modulators | |
| IL145401A0 (en) | Chemokine receptor binding heterocyclic compounds | |
| EG25606A (en) | Glucocorticoid receptor modulators | |
| ZA200203181B (en) | Positive modulators of nicotinic receptor agonists. | |
| IL150059A0 (en) | Novel heterocycles | |
| ZA200203171B (en) | Positive modulators of nicotinic receptor agonists. | |
| GB9903767D0 (en) | Receptor assay | |
| IL146151A0 (en) | Human-g-protein receptor | |
| EP1100896A4 (en) | Dna encoding snorf33 receptor | |
| IL150200A0 (en) | Substituted pyrroles | |
| GB9927905D0 (en) | Encoder device | |
| GC0000265A (en) | Substituted pyrroles | |
| MXPA01011286A (en) | Cyclocarbamate derivatives as progesterone receptor modulators. | |
| PL350603A1 (en) | Stopper | |
| AU5572500A (en) | Vegf receptor antagonists | |
| AUPQ451599A0 (en) | Signalling device | |
| AU2927800A (en) | Signalling device | |
| GB9929139D0 (en) | Liquid application means | |
| PL110283U1 (en) | Interphone | |
| GB9922009D0 (en) | CCR5 Modulators | |
| GB9921375D0 (en) | CCR5 Modulators | |
| GB9922702D0 (en) | CCR5 modulators | |
| AU2512800A (en) | Alpha1-adrenergic receptor antagonists | |
| PL359523A1 (en) | Chemokine receptor binding heterocyclic compounds | |
| TW444989U (en) | Improved structure for handsfree device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |