HK1044539A1 - Functionalized heterocycles as chemokine receptor modulators - Google Patents
Functionalized heterocycles as chemokine receptor modulatorsInfo
- Publication number
- HK1044539A1 HK1044539A1 HK02106357.2A HK02106357A HK1044539A1 HK 1044539 A1 HK1044539 A1 HK 1044539A1 HK 02106357 A HK02106357 A HK 02106357A HK 1044539 A1 HK1044539 A1 HK 1044539A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- chemokine receptor
- receptor modulators
- functionalized heterocycles
- heterocycles
- functionalized
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11565499P | 1999-01-13 | 1999-01-13 | |
PCT/US1999/030434 WO2000042045A2 (en) | 1999-01-13 | 1999-12-20 | Functionalized heterocycles as chemokine receptor modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1044539A1 true HK1044539A1 (en) | 2002-10-25 |
Family
ID=22362668
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK02106357.2A HK1044539A1 (en) | 1999-01-13 | 2002-08-28 | Functionalized heterocycles as chemokine receptor modulators |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP1144415A2 (en) |
JP (1) | JP2002534526A (en) |
KR (1) | KR20010086166A (en) |
CN (1) | CN1344270A (en) |
AP (1) | AP2001002228A0 (en) |
AU (1) | AU1940900A (en) |
BR (1) | BR9916905A (en) |
CA (1) | CA2372197A1 (en) |
CZ (1) | CZ20012502A3 (en) |
EA (1) | EA200100774A1 (en) |
HK (1) | HK1044539A1 (en) |
HU (1) | HUP0202932A3 (en) |
IL (1) | IL144289A0 (en) |
MX (1) | MXPA01007033A (en) |
NO (1) | NO20013456L (en) |
OA (1) | OA11820A (en) |
PL (1) | PL349348A1 (en) |
SK (1) | SK9972001A3 (en) |
WO (1) | WO2000042045A2 (en) |
ZA (1) | ZA200106592B (en) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6951848B2 (en) | 2001-03-12 | 2005-10-04 | Millennium Pharmaceuticals, Inc., | Functionalized heterocycles as modulators of chemokine receptor function and methods of use therefor |
HU230322B1 (en) | 2001-03-29 | 2016-01-28 | Eli Lilly And Co. | N-(2-arylethyl)-benzylamines as antagonists of the 5-ht6 receptor and pharmaceutical compositions containing them |
WO2003035650A1 (en) * | 2001-09-25 | 2003-05-01 | Takeda Chemical Industries, Ltd. | Entry inhibitor |
TWI344955B (en) | 2003-03-14 | 2011-07-11 | Ono Pharmaceutical Co | Heterocyclic rinf having nitrogen atom derivatives and medicament containing the derivatives as active ingredient |
US7498323B2 (en) | 2003-04-18 | 2009-03-03 | Ono Pharmaceuticals Co., Ltd. | Spiro-piperidine compounds and medicinal use thereof |
PE20060598A1 (en) | 2004-09-13 | 2006-08-21 | Ono Pharmaceutical Co | HETEROCYCLE DERIVATIVE CONTAINING NITROGEN AS ANTAGONIST OF CCR5 CHEMOKINE |
EP1889622A4 (en) | 2005-05-31 | 2009-12-23 | Ono Pharmaceutical Co | Spiropiperidine compound and medicinal use thereof |
US7915286B2 (en) | 2005-09-16 | 2011-03-29 | Ranbaxy Laboratories Limited | Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors |
WO2007049771A1 (en) | 2005-10-28 | 2007-05-03 | Ono Pharmaceutical Co., Ltd. | Compound containing basic group and use thereof |
ES2407115T3 (en) | 2005-11-18 | 2013-06-11 | Ono Pharmaceutical Co., Ltd. | Compound containing a basic group and its use |
CN101460458A (en) | 2006-02-15 | 2009-06-17 | 阿勒根公司 | Indole-3-carboxylic acid amide, ester, thioamide and thiol ester compounds bearing aryl or heteroaryl groups having sphingosine-1-phosphate (S1P) receptor antagonist biological activity |
EP1984334B1 (en) * | 2006-02-15 | 2014-04-09 | Allergan, Inc. | Indole-3-carboxylic acid amide, ester, thioamide and thiol ester compounds bearing aryl or heteroaryl groups having sphingosine-1-phosphate (s1p) receptor antagonist biological activity |
EP1995246A4 (en) | 2006-03-10 | 2010-11-17 | Ono Pharmaceutical Co | Nitrogenated heterocyclic derivative, and pharmaceutical agent comprising the derivative as active ingredient |
JP5257068B2 (en) | 2006-05-16 | 2013-08-07 | 小野薬品工業株式会社 | Compound containing acidic group which may be protected and use thereof |
WO2007136300A2 (en) * | 2006-05-23 | 2007-11-29 | Alla Chem, Llc | Substituted indoles and a method for the production and use thereof |
US20090325992A1 (en) | 2006-07-31 | 2009-12-31 | Ono Pharmaceutical Co., Ltd. | Compound having cyclic group bound thereto through spiro binding and use thereof |
US8524917B2 (en) | 2007-01-11 | 2013-09-03 | Allergan, Inc. | 6-substituted indole-3-carboxylic acid amide compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity |
JP2010515750A (en) * | 2007-01-11 | 2010-05-13 | アラーガン インコーポレイテッド | 6-Substituted indole-3-carboxylic acid amide compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity |
WO2010129351A1 (en) | 2009-04-28 | 2010-11-11 | Schepens Eye Research Institute | Method to identify and treat age-related macular degeneration |
CA2799154A1 (en) | 2010-05-12 | 2011-11-17 | Abbvie Inc. | Indazole inhibitors of kinase |
US20140271680A1 (en) | 2011-08-12 | 2014-09-18 | Universite Paris-Est Creteil Val De Marne | Methods and pharmaceutical compositions for treatment of pulmonary hypertension |
JO3459B1 (en) | 2012-09-09 | 2020-07-05 | H Lundbeck As | Pharmaceutical compositions for treating alzheimer's disease |
CN104193669B (en) * | 2014-08-01 | 2016-12-07 | 大连理工大学 | One class Abiduoer analog or its salt, its preparation method and application |
WO2016112088A1 (en) * | 2015-01-06 | 2016-07-14 | Spero Therapeutics, Inc. | Aryloxyacetylindoles and analogs as antibiotic tolerance inhibitors |
CN110256324A (en) * | 2019-06-13 | 2019-09-20 | 苏州莱安医药化学技术有限公司 | A kind of preparation method of 2- methyl -5-OHi |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3549641A (en) * | 1966-06-28 | 1970-12-22 | Warner Lambert Pharmaceutical | Pyrano pyridines and process for their production |
US3518258A (en) * | 1967-05-09 | 1970-06-30 | Warner Lambert Pharmaceutical | Pyrano(3,2-i)quinolizine and process for the production |
US3565903A (en) * | 1967-11-24 | 1971-02-23 | Warner Lambert Pharmaceutical | Pyrano(2,3-b)quinolines and process for their production |
US5635510A (en) * | 1993-05-06 | 1997-06-03 | Merrell Pharmaceuticals Inc. | Substituted pyrrolidin-3-yl-alkyl-piperidines |
HRP960352A2 (en) * | 1996-07-26 | 1998-08-31 | Pliva Pharm & Chem Works | Novel coumarin quinoline carboxylic acids |
AU745687B2 (en) * | 1997-02-26 | 2002-03-28 | Pfizer Inc. | Heteroaryl-hexanoic acid amide derivatives, their preparation and their use as selective inhibitors of MIP-1-alpha binding to its CCR1 receptor |
JP2002501898A (en) * | 1998-02-02 | 2002-01-22 | メルク エンド カムパニー インコーポレーテッド | Cyclic amine modulators of chemokine receptor activity |
-
1999
- 1999-12-20 CN CN99816475A patent/CN1344270A/en active Pending
- 1999-12-20 SK SK997-2001A patent/SK9972001A3/en unknown
- 1999-12-20 BR BR9916905-3A patent/BR9916905A/en not_active Application Discontinuation
- 1999-12-20 EA EA200100774A patent/EA200100774A1/en unknown
- 1999-12-20 PL PL99349348A patent/PL349348A1/en not_active Application Discontinuation
- 1999-12-20 IL IL14428999A patent/IL144289A0/en unknown
- 1999-12-20 HU HU0202932A patent/HUP0202932A3/en unknown
- 1999-12-20 MX MXPA01007033A patent/MXPA01007033A/en unknown
- 1999-12-20 OA OA1200100187A patent/OA11820A/en unknown
- 1999-12-20 CZ CZ20012502A patent/CZ20012502A3/en unknown
- 1999-12-20 EP EP99963110A patent/EP1144415A2/en not_active Withdrawn
- 1999-12-20 JP JP2000593612A patent/JP2002534526A/en active Pending
- 1999-12-20 KR KR1020017008905A patent/KR20010086166A/en not_active Application Discontinuation
- 1999-12-20 AP APAP/P/2001/002228A patent/AP2001002228A0/en unknown
- 1999-12-20 WO PCT/US1999/030434 patent/WO2000042045A2/en not_active Application Discontinuation
- 1999-12-20 AU AU19409/00A patent/AU1940900A/en not_active Abandoned
- 1999-12-20 CA CA002372197A patent/CA2372197A1/en not_active Abandoned
-
2001
- 2001-07-12 NO NO20013456A patent/NO20013456L/en not_active Application Discontinuation
- 2001-08-10 ZA ZA200106592A patent/ZA200106592B/en unknown
-
2002
- 2002-08-28 HK HK02106357.2A patent/HK1044539A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR20010086166A (en) | 2001-09-08 |
CA2372197A1 (en) | 2000-07-20 |
CZ20012502A3 (en) | 2002-03-13 |
OA11820A (en) | 2005-08-17 |
MXPA01007033A (en) | 2003-07-21 |
NO20013456D0 (en) | 2001-07-12 |
HUP0202932A2 (en) | 2002-12-28 |
JP2002534526A (en) | 2002-10-15 |
EA200100774A1 (en) | 2002-02-28 |
IL144289A0 (en) | 2002-05-23 |
NO20013456L (en) | 2001-09-12 |
PL349348A1 (en) | 2002-07-15 |
WO2000042045A2 (en) | 2000-07-20 |
AP2001002228A0 (en) | 2001-09-30 |
AU1940900A (en) | 2000-08-01 |
ZA200106592B (en) | 2002-08-12 |
SK9972001A3 (en) | 2002-03-05 |
EP1144415A2 (en) | 2001-10-17 |
HUP0202932A3 (en) | 2003-07-28 |
BR9916905A (en) | 2002-01-29 |
WO2000042045A3 (en) | 2000-11-09 |
CN1344270A (en) | 2002-04-10 |
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