MX9806182A - Medicamento antiglucocorticoide. - Google Patents

Medicamento antiglucocorticoide.

Info

Publication number
MX9806182A
MX9806182A MX9806182A MX9806182A MX9806182A MX 9806182 A MX9806182 A MX 9806182A MX 9806182 A MX9806182 A MX 9806182A MX 9806182 A MX9806182 A MX 9806182A MX 9806182 A MX9806182 A MX 9806182A
Authority
MX
Mexico
Prior art keywords
aliphatic
pheromones
mammalian cells
carbon atoms
nonsteroidal
Prior art date
Application number
MX9806182A
Other languages
English (en)
Inventor
Sergei Dmitrievich Burlakov
Dmitry Dmitrievich Genkin
Kirill Gennadievich Surkov
Viktor Veniaminovich Tets
Original Assignee
Sergei Dmitrievich Burlakov
Dmitry Dmitrievich Genkin
Kirill Gennadievich Surkov
Viktor Veniaminovich Tets
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sergei Dmitrievich Burlakov, Dmitry Dmitrievich Genkin, Kirill Gennadievich Surkov, Viktor Veniaminovich Tets filed Critical Sergei Dmitrievich Burlakov
Publication of MX9806182A publication Critical patent/MX9806182A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Securing Of Glass Panes Or The Like (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)

Abstract

La invencion tiene relacion con la Medicina y la Veterinaria, concretamente con los preparados medicinales antiglucocorticoides de naturaleza no esteroide. La tarea de la invencion es crear una clase nueva de preparados medicinales con baja toxicidad y alta eficiencia para regular la sensibilidad de las células de los mamíferos de la accion de las hormonas glucocorticoides. Es nueva la aplicacion de la feromona de insectos de naturaleza no esteroides o de su análogo sintético o derivado (que representa un alcohol alifático no saturado con una cadena larga, aldehído o éter) para inhibir selectivamente la accion de las hormonas glucocorticoides sobre las células de los mamíferos. La longitud de la cadena lineal de hidrocarburo de cualquiera de los elementos indicados está en los límites de 10 a 21 átomos de carbono. Además, para aumentar el efecto terapéutico es posible aplicar, al mismo tiempo, dos o más feromonas y/o sus análogos sintéticos y derivados, elegidos por el principio, esencialmente, del diverso carácter hidrofobo, proporcional a las longitudes de las cadenas alifáticas lineales de los hidrocarburos: la diferencia en las longitudes de las cadenas indicadas debe ser no menor de cinco. Se citan ejemplos para obtener medicamentos y los resultados de los experimentos comparativos que ha mostrado su alta eficacia.
MX9806182A 1996-01-31 1998-07-31 Medicamento antiglucocorticoide. MX9806182A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU96101194/14A RU2125446C1 (ru) 1996-01-31 1996-01-31 Антиглюкокортикоидное лекарственное средство

Publications (1)

Publication Number Publication Date
MX9806182A true MX9806182A (es) 1998-10-31

Family

ID=20175968

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9806182A MX9806182A (es) 1996-01-31 1998-07-31 Medicamento antiglucocorticoide.

Country Status (24)

Country Link
US (1) US5965623A (es)
EP (1) EP0896819A4 (es)
JP (1) JPH11504946A (es)
KR (1) KR100347862B1 (es)
CN (1) CN1213964A (es)
AU (1) AU710479B2 (es)
BG (1) BG102709A (es)
BR (1) BR9612470A (es)
CA (1) CA2244985A1 (es)
CZ (1) CZ160598A3 (es)
EE (1) EE9800209A (es)
GE (1) GEP20001955B (es)
HU (1) HUP9900504A2 (es)
LT (1) LT4441B (es)
LV (1) LV12177B (es)
MD (1) MD1430B1 (es)
MX (1) MX9806182A (es)
NO (1) NO983508D0 (es)
PL (1) PL187564B1 (es)
RU (1) RU2125446C1 (es)
SI (1) SI9620053A (es)
SK (1) SK65598A3 (es)
UA (1) UA48212C2 (es)
WO (1) WO1997027845A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001039766A2 (en) * 1999-12-01 2001-06-07 Alydar Pharmaceuticals Ltd. Screening invertebrate pheromones for therapeutic activity
US6548706B2 (en) * 1999-12-23 2003-04-15 Aerojet Fine Chemicals Llc Preparation of 2S,3S-N-isobutyl-N-(2-hydroxy-3-amino-4-phenylbutyl) -p-nitrobenzenesulfonylamide hydrochloride and other derivatives of 2-hydroxy-1,3-diamines
WO2002072809A1 (en) * 2001-03-12 2002-09-19 Alydar Pharmaceuticals, Inc. Screening non-peptide, non-steroid invertebrate pheromone compounds for mitogen-activated protein kinase modulating activity
US6806293B1 (en) 2001-03-12 2004-10-19 Darley Pharmaceuticals Ltd Use of pheromone compounds having MAP kinase modulating activity
WO2003092614A2 (en) * 2002-05-02 2003-11-13 Hickle Randall S Lipid removal from the body
US6752649B2 (en) * 2002-11-07 2004-06-22 Xentris, Llc Illuminated indicia power supply apparatus and method of manufacture
DE10335845B4 (de) * 2003-05-09 2006-08-31 Müller, Martina, Dr.med. Pheromone als Antikrebsmittel
WO2010017177A1 (en) * 2008-08-06 2010-02-11 The Trustees Of The University Of Pennsylvania Ultrasonically induced release from polymer vesicles

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US161926A (en) 1875-04-13 Improvement in ink-wells
US2900756A (en) * 1958-12-09 1959-08-25 Jacobson Martin Attractants for the gypsy moth
EP0149847A3 (en) * 1983-12-26 1989-11-08 Eisai Co., Ltd. Therapeutic and preventive agent containing dolichol
JPH0759504B2 (ja) * 1986-01-23 1995-06-28 エーザイ株式会社 ポリプレニルアルコ−ル含有注射剤
US5019569A (en) * 1986-11-03 1991-05-28 Ortho Pharmaceutical Corporation Reversal of glucocorticoid-induced skin atrophy
US4740627A (en) * 1987-05-21 1988-04-26 Phillips Petroleum Company Synthesis of E,Z-11-tetradecen-1-al
DE68902753T2 (de) 1988-02-29 1993-01-21 Pfizer Mittel zur erhoehung des transdermalen penetrationsflusses.
US5190978A (en) * 1989-09-29 1993-03-02 Dai-Ichi Kogyo Seiyaku Co. Ltd. Carcinostatic compositions and methods

Also Published As

Publication number Publication date
BG102709A (en) 1999-06-30
LV12177B (lv) 1999-06-20
LV12177A (lv) 1998-12-20
CN1213964A (zh) 1999-04-14
EP0896819A1 (en) 1999-02-17
LT98054A (en) 1998-10-26
AU710479B2 (en) 1999-09-23
JPH11504946A (ja) 1999-05-11
BR9612470A (pt) 1999-07-13
LT4441B (lt) 1999-01-25
NO983508L (no) 1998-07-30
RU2125446C1 (ru) 1999-01-27
SI9620053A (sl) 1998-04-30
US5965623A (en) 1999-10-12
KR19990076946A (ko) 1999-10-25
PL187564B1 (pl) 2004-08-31
PL322596A1 (en) 1998-02-02
NO983508D0 (no) 1998-07-30
KR100347862B1 (ko) 2003-01-24
HUP9900504A2 (en) 1999-09-28
CA2244985A1 (en) 1997-08-07
GEP20001955B (en) 2000-03-05
WO1997027845A1 (fr) 1997-08-07
EE9800209A (et) 1998-12-15
AU4636396A (en) 1997-08-22
MD1430B1 (ro) 2000-03-31
SK65598A3 (en) 1998-09-09
EP0896819A4 (en) 2001-11-07
CZ160598A3 (cs) 1998-08-12
UA48212C2 (uk) 2002-08-15

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