AR009231A1 - Formulaciones en aerosol de formoterol. - Google Patents
Formulaciones en aerosol de formoterol.Info
- Publication number
- AR009231A1 AR009231A1 ARP970102437A ARP970102437A AR009231A1 AR 009231 A1 AR009231 A1 AR 009231A1 AR P970102437 A ARP970102437 A AR P970102437A AR P970102437 A ARP970102437 A AR P970102437A AR 009231 A1 AR009231 A1 AR 009231A1
- Authority
- AR
- Argentina
- Prior art keywords
- hfa
- drug
- aerosol formulations
- formoterol
- hfa13
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/124—Aerosols; Foams characterised by the propellant
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Una formulacion de suspension farmacéutica adecuada para administracion en aerosol que tiene 0,0025 a 0,1% p/p de Formoterol micronizado, o una sal deadicion de ácido del mismo, desde 0,1 5,0% p/p de etanol, HFA 227 o una mezcla de HFA 227 y HFA13 4a, y opcionalmente un agente tensioactivo distinto de unmonoglicerido diacetilado o monoacetilado, donde la formulacion es además caracterizada porque no exhibe sustancialmente crecimiento en el tamano departícula o cambio en la morfologíadel cristal de la droga en un periodo prolongado, es sustancial y fácilmente redispersible y por redispersion noflocula tan rápidamente que prevenga una dosis reproducible de la droga.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9612297.3A GB9612297D0 (en) | 1996-06-11 | 1996-06-11 | Medicinal aerosol formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
AR009231A1 true AR009231A1 (es) | 2000-04-12 |
Family
ID=10795182
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP970102437A AR009231A1 (es) | 1996-06-11 | 1997-06-04 | Formulaciones en aerosol de formoterol. |
Country Status (16)
Country | Link |
---|---|
EP (2) | EP0934057B1 (es) |
JP (1) | JP5000793B2 (es) |
AR (1) | AR009231A1 (es) |
AT (1) | ATE275940T1 (es) |
AU (1) | AU726382B2 (es) |
CA (1) | CA2257841C (es) |
DE (1) | DE69730723T2 (es) |
DK (1) | DK0934057T3 (es) |
ES (1) | ES2229366T3 (es) |
GB (1) | GB9612297D0 (es) |
ID (1) | ID19520A (es) |
NO (1) | NO320403B1 (es) |
NZ (1) | NZ333202A (es) |
PT (1) | PT934057E (es) |
WO (1) | WO1997047286A1 (es) |
ZA (1) | ZA974546B (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6054488A (en) * | 1996-06-11 | 2000-04-25 | 3M Innovative Properties Company | Medicinal aerosol formulations of formoterol |
GB9616237D0 (en) | 1996-08-01 | 1996-09-11 | Norton Healthcare Ltd | Aerosol formulations |
US20010031244A1 (en) | 1997-06-13 | 2001-10-18 | Chiesi Farmaceutici S.P.A. | Pharmaceutical aerosol composition |
US6423298B2 (en) * | 1998-06-18 | 2002-07-23 | Boehringer Ingelheim Pharmaceuticals, Inc. | Pharmaceutical formulations for aerosols with two or more active substances |
US6451285B2 (en) * | 1998-06-19 | 2002-09-17 | Baker Norton Pharmaceuticals, Inc. | Suspension aerosol formulations containing formoterol fumarate and a fluoroalkane propellant |
DE19847969A1 (de) * | 1998-10-17 | 2000-04-20 | Boehringer Ingelheim Pharma | Lagerfähig flüssige Formulierung mit Formoterol |
WO2000023065A2 (de) * | 1998-10-17 | 2000-04-27 | Boehringer Ingelheim Pharma Kg | Lagerfähiges wirkstoffkonzentrat mit formoterol |
IT1303788B1 (it) * | 1998-11-25 | 2001-02-23 | Chiesi Farma Spa | Formulazioni di aerosol medicinali. |
DZ2947A1 (fr) | 1998-11-25 | 2004-03-15 | Chiesi Farma Spa | Inhalateur à compteur de dose sous pression. |
US6004537A (en) * | 1998-12-18 | 1999-12-21 | Baker Norton Pharmaceuticals, Inc. | Pharmaceutical solution aerosol formulations containing fluoroalkanes, budesonide and formoterol |
US6290930B1 (en) | 1998-12-18 | 2001-09-18 | Baker Norton Pharmaceuticals, Inc. | Pharmaceutical solution aerosol formulations containing fluoroalkanes and budesonide |
IT1313553B1 (it) | 1999-07-23 | 2002-09-09 | Chiesi Farma Spa | Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione. |
IT1317846B1 (it) | 2000-02-22 | 2003-07-15 | Chiesi Farma Spa | Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva. |
BR0015884A (pt) * | 2000-05-22 | 2003-07-08 | Chiesi Farma Spa | Formulações de soluções farmacêuticas estáveis para inaladores de dose medida pressurizados |
SE0004750D0 (sv) | 2000-12-19 | 2000-12-19 | Astrazeneca Ab | Novel formulation |
US20030055026A1 (en) | 2001-04-17 | 2003-03-20 | Dey L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
SI1273292T1 (en) | 2001-07-02 | 2004-12-31 | Chiesi Farmaceutici S.P.A. | Optimised formulation of tobramycin for aerosolization |
AR036358A1 (es) * | 2001-08-28 | 2004-09-01 | Schering Corp | Un inhalador de dosis medidas que contiene una formulacion de suspension en aerosol para inhalacion, un proceso para la produccion de la formulacion, el producto y el uso de una formulacion para la manufactura de un medicamento de asma |
GB0207899D0 (en) * | 2002-04-05 | 2002-05-15 | 3M Innovative Properties Co | Formoterol and cielesonide aerosol formulations |
GB0207906D0 (en) | 2002-04-05 | 2002-05-15 | 3M Innovative Properties Co | Formoterol and mometasone aerosol formulations |
MXPA05002248A (es) * | 2002-08-27 | 2005-06-08 | Schering Corp | Procedimiento para producir formulaciones de inhalador de dosis medida. |
US8435497B2 (en) | 2003-06-13 | 2013-05-07 | Takeda Gmbh | Formoterol of and ciclesonide combination |
TWI359675B (en) | 2003-07-10 | 2012-03-11 | Dey L P | Bronchodilating β-agonist compositions |
CA2542530A1 (en) * | 2003-10-20 | 2005-05-12 | Schering Corporation | Pharmaceutical aerosol compositions |
EP1925293A3 (en) * | 2003-10-20 | 2010-01-13 | Schering Corporation | Pharmaceutical aerosol compositions |
EP1595531A1 (en) | 2004-05-13 | 2005-11-16 | CHIESI FARMACEUTICI S.p.A. | Stable pharmaceutical solution formulations for pressurized metered dose inhalers |
JP2010506941A (ja) * | 2006-10-17 | 2010-03-04 | リセラ,インク. | 甲状腺眼症の治療のための方法、組成物及び製剤 |
US8815258B2 (en) | 2009-05-29 | 2014-08-26 | Pearl Therapeutics, Inc. | Compositions, methods and systems for respiratory delivery of two or more active agents |
LT2435025T (lt) | 2009-05-29 | 2016-09-26 | Pearl Therapeutics, Inc. | Veikliosios medžiagos tiekimas per kvėpavimo takus |
RS54721B1 (en) * | 2009-10-02 | 2016-08-31 | Chiesi Farmaceutici S.P.A. | PHARMACEUTICAL AEROSOL FORMOTEROL FORMULATION AND BECLOMETHASONE DIPROPIONATE |
JP6454323B2 (ja) | 2013-03-15 | 2019-01-16 | パール セラピューティクス,インコーポレイテッド | 粒子状結晶性材料のコンディショニングのための方法及びシステム |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0460064A4 (en) * | 1989-02-23 | 1992-04-01 | Rorer International (Holdings) Inc. | Therapeutic aerosol formulations |
IE67185B1 (en) * | 1990-02-02 | 1996-03-06 | Fisons Plc | Propellant compositions |
GB9024365D0 (en) * | 1990-11-09 | 1991-01-02 | Glaxo Group Ltd | Medicaments |
EP0504112A3 (en) * | 1991-03-14 | 1993-04-21 | Ciba-Geigy Ag | Pharmaceutical aerosol formulations |
JPH06508149A (ja) * | 1991-06-10 | 1994-09-14 | シェリング・コーポレーション | クロロフルオロカーボン不含エーロゾル製剤 |
EP0588897B1 (en) * | 1991-06-10 | 1996-02-28 | Schering Corporation | Non-chlorofluorocarbon aerosol formulations |
IL104068A (en) * | 1991-12-12 | 1998-10-30 | Glaxo Group Ltd | Pharmaceutical preparations in a spray without surfactant containing 1, 1, 1, 2 tetrafluoroethane or 1,1,2,3,3 petafluor N propane as propellant |
ATE128350T1 (de) * | 1991-12-12 | 1995-10-15 | Glaxo Group Ltd | Pharmazeutische aerosolformulierung. |
EP0717987B1 (en) * | 1991-12-18 | 2001-08-29 | Minnesota Mining And Manufacturing Company | Suspension aerosol formulations |
GB9207400D0 (en) * | 1992-04-02 | 1992-05-13 | Smithkline Beecham Plc | Novel use |
US5354934A (en) * | 1993-02-04 | 1994-10-11 | Amgen Inc. | Pulmonary administration of erythropoietin |
GB9425160D0 (en) * | 1994-12-10 | 1995-02-08 | Glaxo Group Ltd | Medicaments |
GB9426252D0 (en) * | 1994-12-24 | 1995-02-22 | Glaxo Group Ltd | Pharmaceutical composition |
-
1996
- 1996-06-11 GB GBGB9612297.3A patent/GB9612297D0/en active Pending
-
1997
- 1997-05-23 ZA ZA974546A patent/ZA974546B/xx unknown
- 1997-06-02 EP EP97929756A patent/EP0934057B1/en not_active Expired - Lifetime
- 1997-06-02 ES ES97929756T patent/ES2229366T3/es not_active Expired - Lifetime
- 1997-06-02 EP EP03014565A patent/EP1400239A1/en not_active Withdrawn
- 1997-06-02 AT AT97929756T patent/ATE275940T1/de not_active IP Right Cessation
- 1997-06-02 DK DK97929756T patent/DK0934057T3/da active
- 1997-06-02 DE DE69730723T patent/DE69730723T2/de not_active Expired - Lifetime
- 1997-06-02 NZ NZ333202A patent/NZ333202A/en not_active IP Right Cessation
- 1997-06-02 JP JP50165698A patent/JP5000793B2/ja not_active Expired - Lifetime
- 1997-06-02 WO PCT/US1997/009471 patent/WO1997047286A1/en active IP Right Grant
- 1997-06-02 PT PT97929756T patent/PT934057E/pt unknown
- 1997-06-02 AU AU33739/97A patent/AU726382B2/en not_active Expired
- 1997-06-02 CA CA002257841A patent/CA2257841C/en not_active Expired - Lifetime
- 1997-06-04 AR ARP970102437A patent/AR009231A1/es unknown
- 1997-06-09 ID IDP971970A patent/ID19520A/id unknown
-
1998
- 1998-12-07 NO NO19985720A patent/NO320403B1/no unknown
Also Published As
Publication number | Publication date |
---|---|
ES2229366T3 (es) | 2005-04-16 |
ZA974546B (en) | 1998-11-23 |
WO1997047286A1 (en) | 1997-12-18 |
NO320403B1 (no) | 2005-11-28 |
EP1400239A1 (en) | 2004-03-24 |
CA2257841A1 (en) | 1997-12-18 |
NZ333202A (en) | 2000-06-23 |
JP5000793B2 (ja) | 2012-08-15 |
NO985720L (no) | 1999-02-11 |
EP0934057B1 (en) | 2004-09-15 |
CA2257841C (en) | 2008-05-20 |
ATE275940T1 (de) | 2004-10-15 |
AU726382B2 (en) | 2000-11-02 |
DK0934057T3 (da) | 2005-01-24 |
PT934057E (pt) | 2004-12-31 |
DE69730723D1 (de) | 2004-10-21 |
EP0934057A1 (en) | 1999-08-11 |
ID19520A (id) | 1998-07-16 |
NO985720D0 (no) | 1998-12-07 |
GB9612297D0 (en) | 1996-08-14 |
DE69730723T2 (de) | 2005-10-06 |
AU3373997A (en) | 1998-01-07 |
JP2000513340A (ja) | 2000-10-10 |
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