MX9804701A - METODO Y COMPOSICIONES PARA LA SINTESIS DE NUCLEOSIDAS DE DIOXOLANO CON CONFIGURACION beta. - Google Patents
METODO Y COMPOSICIONES PARA LA SINTESIS DE NUCLEOSIDAS DE DIOXOLANO CON CONFIGURACION beta.Info
- Publication number
- MX9804701A MX9804701A MX9804701A MX9804701A MX9804701A MX 9804701 A MX9804701 A MX 9804701A MX 9804701 A MX9804701 A MX 9804701A MX 9804701 A MX9804701 A MX 9804701A MX 9804701 A MX9804701 A MX 9804701A
- Authority
- MX
- Mexico
- Prior art keywords
- beta
- compositions
- synthesis
- configuration
- dioxolane nucleosides
- Prior art date
Links
- WNXJIVFYUVYPPR-UHFFFAOYSA-N 1,3-dioxolane Chemical compound C1COCO1 WNXJIVFYUVYPPR-UHFFFAOYSA-N 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 239000002777 nucleoside Substances 0.000 title 1
- 230000001279 glycosylating effect Effects 0.000 abstract 1
- 229940127073 nucleoside analogue Drugs 0.000 abstract 1
- 230000000707 stereoselective effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9525606.1A GB9525606D0 (en) | 1995-12-14 | 1995-12-14 | Method and compositions for the synthesis of dioxolane nucleosides with - configuration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9804701A true MX9804701A (es) | 1998-10-31 |
Family
ID=10785435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9804701A MX9804701A (es) | 1995-12-14 | 1998-06-11 | METODO Y COMPOSICIONES PARA LA SINTESIS DE NUCLEOSIDAS DE DIOXOLANO CON CONFIGURACION beta. |
Country Status (27)
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6898498A (en) | 1997-04-07 | 1998-10-30 | Triangle Pharmaceuticals, Inc. | Use of mkc-442 in combination with other antiviral agents |
| MXPA01001552A (es) | 1998-08-12 | 2004-08-23 | Triangle Pharmaceuticals Inc | Metodo de elaboracion de 1,3-oxatiolan-nucleosidos. |
| US6979561B1 (en) | 1998-10-09 | 2005-12-27 | Gilead Sciences, Inc. | Non-homogeneous systems for the resolution of enantiomeric mixtures |
| HUP0104827A3 (en) | 1998-12-23 | 2002-08-28 | Shire Biochem Inc Laval | Antiviral nucleoside analogues |
| CA2362570A1 (en) * | 1999-02-11 | 2000-08-17 | Shire Biochem Inc. | Stereoselective synthesis of nucleoside analogues |
| ATE269081T1 (de) * | 1999-09-24 | 2004-07-15 | Shire Biochem Inc | Dioxolan nukleosidanalogen zur behandlung und vorbeugung von viralen infektionen |
| US6566365B1 (en) | 1999-11-04 | 2003-05-20 | Biochem Pharma Inc. | Method for the treatment of Flaviviridea viral infection using nucleoside analogues |
| BR0104461A (pt) * | 2000-02-10 | 2002-08-06 | Mitsui Chemicals Inc | Processo seletivo para produzir um anÈmero a partir de um derivado de sacarìdeo 1-fosforilado e processo para produzir um nucleosìdeo |
| AU3144801A (en) | 2000-02-11 | 2001-08-20 | Shire Biochem Inc. | Stereoselective synthesis of nucleoside analogues |
| WO2002051852A1 (fr) * | 2000-12-27 | 2002-07-04 | Mitsui Chemicals, Inc. | Procede de production d'un derive de saccharide non naturel |
| ES2253544T3 (es) | 2001-03-01 | 2006-06-01 | Gilead Sciences, Inc. | Formas poliformicas y otras cristalinas de cis-ftc. |
| AU2002329970A1 (en) * | 2001-09-04 | 2003-03-18 | Isis Pharmaceuticals, Inc. | Pyrrolo(2,3-d)pyrimidines for inhibiting rna-dependent rna viral polymerase |
| AU2002336864B2 (en) * | 2001-11-02 | 2006-08-17 | Shire Biochem Inc. | Pharmaceutical compositions for the treatment of leukemia comprising dioxolane nucleosides analogs |
| CA2470255C (en) | 2001-12-14 | 2012-01-17 | Kyoichi A. Watanabe | N4-acylcytosine nucleosides for treatment of viral infections |
| JP4441265B2 (ja) * | 2002-01-25 | 2010-03-31 | シャー バイオケム インコーポレイティッド | ジオキソランヌクレオシド類似体の製造方法 |
| MXPA05001451A (es) | 2002-08-06 | 2005-09-30 | Pharmasset Ltd | Procesos para preparar nucleosidos de 1,3-dioxolano. |
| CN101724110B (zh) | 2002-10-15 | 2013-03-27 | 埃克森美孚化学专利公司 | 用于烯烃聚合的多催化剂体系和由其生产的聚合物 |
| DE10335061B4 (de) | 2003-07-31 | 2005-11-17 | Wacker-Chemie Gmbh | Verfahren zur Herstellung von OH-geschützten [4-(2,6-damino-9H-purin-9-yl)-1,3-dioxolan-2-yl]methanol-Derivaten |
| CN105039489A (zh) * | 2004-02-03 | 2015-11-11 | 埃莫里大学 | 制备1,3-二氧戊环核苷的方法 |
| US7749531B2 (en) * | 2005-06-08 | 2010-07-06 | Indicator Systems International | Apparatus and method for detecting bacterial growth beneath a wound dressing |
| BRPI0813036A2 (pt) * | 2007-07-30 | 2017-10-24 | Rfs Pharma Llc | processo estereosseletivo para preparar derivados do nucleosídeo dioxolana de purina. |
| CN101862676B (zh) * | 2009-04-17 | 2012-01-25 | 中国石油化工股份有限公司 | 大孔径sba-15介孔材料-三氟甲磺酸铜复合催化剂、制备方法及应用 |
| CN103288806A (zh) * | 2013-07-02 | 2013-09-11 | 山东大学 | 一种曲沙他滨的合成方法 |
| WO2018022263A1 (en) | 2016-07-29 | 2018-02-01 | Exxonmobil Chemical Patents Inc. | Polymerization processes using high molecular weight polyhydric quenching agents |
| WO2019245444A1 (en) | 2018-06-21 | 2019-12-26 | Medivir Ab | Base-modified cytidine nucleotides for leukemia therapy |
| JP7337539B2 (ja) * | 2018-06-21 | 2023-09-04 | メディヴィル・アクチエボラーグ | 白血病療法のための塩基修飾シチジンヌクレオチド |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5276151A (en) * | 1990-02-01 | 1994-01-04 | Emory University | Method of synthesis of 1,3-dioxolane nucleosides |
| JPH0673086A (ja) * | 1992-06-22 | 1994-03-15 | Eli Lilly & Co | 立体選択的な陰イオングリコシル化法 |
-
1995
- 1995-12-14 GB GBGB9525606.1A patent/GB9525606D0/en active Pending
-
1996
- 1996-12-13 AP APAP/P/1998/001252A patent/AP879A/en active
- 1996-12-13 US US08/849,722 patent/US5922867A/en not_active Expired - Lifetime
- 1996-12-13 CA CA002237730A patent/CA2237730C/en not_active Expired - Lifetime
- 1996-12-13 TW TW085115392A patent/TW341574B/zh active
- 1996-12-13 EP EP96941539A patent/EP0970074B1/en not_active Expired - Lifetime
- 1996-12-13 KR KR10-1998-0704473A patent/KR100406159B1/ko not_active Expired - Fee Related
- 1996-12-13 PT PT96941539T patent/PT970074E/pt unknown
- 1996-12-13 IL IL12466396A patent/IL124663A/en not_active IP Right Cessation
- 1996-12-13 DE DE69620042T patent/DE69620042T2/de not_active Expired - Lifetime
- 1996-12-13 CN CN96199879A patent/CN1080263C/zh not_active Expired - Lifetime
- 1996-12-13 AU AU10893/97A patent/AU706328B2/en not_active Expired
- 1996-12-13 NZ NZ323855A patent/NZ323855A/xx unknown
- 1996-12-13 ES ES96941539T patent/ES2172697T3/es not_active Expired - Lifetime
- 1996-12-13 JP JP52157397A patent/JP3229990B2/ja not_active Expired - Lifetime
- 1996-12-13 AT AT96941539T patent/ATE214699T1/de not_active IP Right Cessation
- 1996-12-13 ZA ZA9610544A patent/ZA9610544B/xx unknown
- 1996-12-13 IN IN2810DE1996 patent/IN187349B/en unknown
- 1996-12-13 HU HU9901050A patent/HU224076B1/hu active IP Right Grant
- 1996-12-13 DK DK96941539T patent/DK0970074T3/da active
- 1996-12-13 PL PL96327443A patent/PL188447B1/pl not_active IP Right Cessation
- 1996-12-13 WO PCT/CA1996/000845 patent/WO1997021706A1/en active IP Right Grant
- 1996-12-13 IL IL14415596A patent/IL144155A/xx not_active IP Right Cessation
- 1996-12-13 BR BR9612351A patent/BR9612351A/pt not_active Application Discontinuation
- 1996-12-13 EA EA199800555A patent/EA000844B1/ru not_active IP Right Cessation
-
1998
- 1998-06-09 OA OA9800077A patent/OA11094A/en unknown
- 1998-06-11 MX MX9804701A patent/MX9804701A/es unknown
- 1998-06-12 NO NO982716A patent/NO309901B1/no unknown
-
1999
- 1999-02-17 US US09/251,431 patent/US6069250A/en not_active Expired - Lifetime
-
2001
- 2001-07-05 IL IL14415501A patent/IL144155A0/xx unknown
- 2001-11-16 US US09/987,845 patent/US20020058670A1/en not_active Abandoned
-
2002
- 2002-10-02 US US10/262,107 patent/US20030060476A1/en not_active Abandoned
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