NO982716L - FremgangsmÕte og blandinger for syntese av dioksalan-nukleotider med <beta>-konfigurasjon - Google Patents

FremgangsmÕte og blandinger for syntese av dioksalan-nukleotider med <beta>-konfigurasjon

Info

Publication number
NO982716L
NO982716L NO982716A NO982716A NO982716L NO 982716 L NO982716 L NO 982716L NO 982716 A NO982716 A NO 982716A NO 982716 A NO982716 A NO 982716A NO 982716 L NO982716 L NO 982716L
Authority
NO
Norway
Prior art keywords
dioxalane
nucleotides
beta
synthesis
compositions
Prior art date
Application number
NO982716A
Other languages
English (en)
Other versions
NO309901B1 (no
NO982716D0 (no
Inventor
Tarek Mansour
Alex Cimpoia
Krzystof Bednarski
Original Assignee
Iaf Biochem Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iaf Biochem Int filed Critical Iaf Biochem Int
Publication of NO982716D0 publication Critical patent/NO982716D0/no
Publication of NO982716L publication Critical patent/NO982716L/no
Publication of NO309901B1 publication Critical patent/NO309901B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO982716A 1995-12-14 1998-06-12 FremgangsmÕte for syntese av dioksalan-nukleotider med <beta>- konfigurasjon NO309901B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9525606.1A GB9525606D0 (en) 1995-12-14 1995-12-14 Method and compositions for the synthesis of dioxolane nucleosides with › - configuration
PCT/CA1996/000845 WO1997021706A1 (en) 1995-12-14 1996-12-13 METHOD AND COMPOSITIONS FOR THE SYNTHESIS OF DIOXOLANE NUCLEOSIDES WITH β-CONFIGURATION

Publications (3)

Publication Number Publication Date
NO982716D0 NO982716D0 (no) 1998-06-12
NO982716L true NO982716L (no) 1998-06-12
NO309901B1 NO309901B1 (no) 2001-04-17

Family

ID=10785435

Family Applications (1)

Application Number Title Priority Date Filing Date
NO982716A NO309901B1 (no) 1995-12-14 1998-06-12 FremgangsmÕte for syntese av dioksalan-nukleotider med <beta>- konfigurasjon

Country Status (28)

Country Link
US (4) US5922867A (no)
EP (1) EP0970074B1 (no)
JP (1) JP3229990B2 (no)
KR (1) KR100406159B1 (no)
CN (1) CN1080263C (no)
AP (1) AP879A (no)
AT (1) ATE214699T1 (no)
AU (1) AU706328B2 (no)
BR (1) BR9612351A (no)
CA (1) CA2237730C (no)
DE (1) DE69620042T2 (no)
DK (1) DK0970074T3 (no)
EA (1) EA000844B1 (no)
ES (1) ES2172697T3 (no)
GB (1) GB9525606D0 (no)
HK (1) HK1017886A1 (no)
HU (1) HU224076B1 (no)
IL (3) IL144155A (no)
IN (1) IN187349B (no)
MX (1) MX9804701A (no)
NO (1) NO309901B1 (no)
NZ (1) NZ323855A (no)
OA (1) OA11094A (no)
PL (1) PL188447B1 (no)
PT (1) PT970074E (no)
TW (1) TW341574B (no)
WO (1) WO1997021706A1 (no)
ZA (1) ZA9610544B (no)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001518899A (ja) 1997-04-07 2001-10-16 トライアングル ファーマシューティカルズ,インコーポレイティド 他の抗ウイルス剤との組合せにおけるmkc−442の使用
EP1535921A1 (en) 1998-08-12 2005-06-01 Gilead Sciences, Inc. Method of manufacture of 1,3-oxathiolane nucleosides
US6979561B1 (en) * 1998-10-09 2005-12-27 Gilead Sciences, Inc. Non-homogeneous systems for the resolution of enantiomeric mixtures
DK1140937T3 (da) * 1998-12-23 2004-03-22 Shire Biochem Inc Antivirale nucleosid-analoger
AU2653200A (en) * 1999-02-11 2000-08-29 Biochem Pharma Inc. Stereoselective synthesis of nucleoside analogues
DE60011637T2 (de) * 1999-09-24 2004-11-11 Shire Biochem Inc., Laval Dioxolan nukleosidanalogen zur behandlung und vorbeugung von viralen infektionen
US6566365B1 (en) 1999-11-04 2003-05-20 Biochem Pharma Inc. Method for the treatment of Flaviviridea viral infection using nucleoside analogues
EP1178051B1 (en) * 2000-02-10 2008-05-28 Mitsui Chemicals, Inc. Process for selectively producing 1-phosphorylated sugar derivative anomer and process for producing nucleoside
AU3144801A (en) 2000-02-11 2001-08-20 Shire Biochem Inc. Stereoselective synthesis of nucleoside analogues
WO2002051852A1 (fr) * 2000-12-27 2002-07-04 Mitsui Chemicals, Inc. Procede de production d'un derive de saccharide non naturel
DK1389207T3 (da) * 2001-03-01 2006-04-18 Gilead Sciences Inc Polymorfe og andre krystallinske former af cis-FTC
WO2003020222A2 (en) * 2001-09-04 2003-03-13 Merck & Co., Inc. PYRROLO[2,3-d]PYRIMIDINES FOR INHIBITING RNA-DEPENDENT RNA VIRAL POLYMERASE
AU2002336864B2 (en) * 2001-11-02 2006-08-17 Shire Biochem Inc. Pharmaceutical compositions for the treatment of leukemia comprising dioxolane nucleosides analogs
EP1569652A4 (en) 2001-12-14 2008-07-02 Pharmasset Inc NUCLEOSIDES N SP 4 / SP-ACYLCYTOSINES FOR THE TREATMENT OF VIRAL INFECTIONS
US20050085638A1 (en) * 2002-01-25 2005-04-21 Shire Biochem Inc Process for producing dioxolane nucleoside analogues
KR101108115B1 (ko) 2002-08-06 2012-01-31 파마셋 인코포레이티드 1,3-디옥솔란 뉴클레오사이드의 제조 방법
CN101724110B (zh) 2002-10-15 2013-03-27 埃克森美孚化学专利公司 用于烯烃聚合的多催化剂体系和由其生产的聚合物
DE10335061B4 (de) * 2003-07-31 2005-11-17 Wacker-Chemie Gmbh Verfahren zur Herstellung von OH-geschützten [4-(2,6-damino-9H-purin-9-yl)-1,3-dioxolan-2-yl]methanol-Derivaten
KR101157468B1 (ko) * 2004-02-03 2012-07-06 에모리 유니버시티 1,3-디옥솔란 뉴클레오시드 제조방법
US7749531B2 (en) * 2005-06-08 2010-07-06 Indicator Systems International Apparatus and method for detecting bacterial growth beneath a wound dressing
BRPI0813036A2 (pt) * 2007-07-30 2017-10-24 Rfs Pharma Llc processo estereosseletivo para preparar derivados do nucleosídeo dioxolana de purina.
CN101862676B (zh) * 2009-04-17 2012-01-25 中国石油化工股份有限公司 大孔径sba-15介孔材料-三氟甲磺酸铜复合催化剂、制备方法及应用
CN103288806A (zh) * 2013-07-02 2013-09-11 山东大学 一种曲沙他滨的合成方法
WO2018022263A1 (en) 2016-07-29 2018-02-01 Exxonmobil Chemical Patents Inc. Polymerization processes using high molecular weight polyhydric quenching agents
JP7337539B2 (ja) * 2018-06-21 2023-09-04 メディヴィル・アクチエボラーグ 白血病療法のための塩基修飾シチジンヌクレオチド
WO2019245444A1 (en) 2018-06-21 2019-12-26 Medivir Ab Base-modified cytidine nucleotides for leukemia therapy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5276151A (en) * 1990-02-01 1994-01-04 Emory University Method of synthesis of 1,3-dioxolane nucleosides
CN1086519A (zh) * 1992-06-22 1994-05-11 伊莱利利公司 立体有择阴离子糖基化方法

Also Published As

Publication number Publication date
KR19990072141A (ko) 1999-09-27
AU1089397A (en) 1997-07-03
PL327443A1 (en) 1998-12-07
IL144155A (en) 2003-07-06
JP2000501714A (ja) 2000-02-15
EP0970074A1 (en) 2000-01-12
HUP9901050A3 (en) 2001-05-28
CN1208414A (zh) 1999-02-17
DE69620042D1 (de) 2002-04-25
CA2237730A1 (en) 1997-06-19
IL124663A0 (en) 1998-12-06
WO1997021706A1 (en) 1997-06-19
DE69620042T2 (de) 2002-10-17
GB9525606D0 (en) 1996-02-14
TW341574B (en) 1998-10-01
HK1017886A1 (en) 1999-12-03
OA11094A (en) 2003-03-13
NO309901B1 (no) 2001-04-17
ZA9610544B (en) 1997-07-29
CA2237730C (en) 2001-12-04
HU224076B1 (hu) 2005-05-30
ATE214699T1 (de) 2002-04-15
US20020058670A1 (en) 2002-05-16
CN1080263C (zh) 2002-03-06
BR9612351A (pt) 1999-07-13
HUP9901050A2 (hu) 2001-04-28
MX9804701A (es) 1998-10-31
EA000844B1 (ru) 2000-06-26
AP879A (en) 2000-10-02
NZ323855A (en) 1999-11-29
EA199800555A1 (ru) 1999-02-25
PT970074E (pt) 2002-09-30
US6069250A (en) 2000-05-30
US20030060476A1 (en) 2003-03-27
AU706328B2 (en) 1999-06-17
IN187349B (no) 2002-03-30
DK0970074T3 (da) 2002-07-15
NO982716D0 (no) 1998-06-12
KR100406159B1 (ko) 2004-11-16
US5922867A (en) 1999-07-13
JP3229990B2 (ja) 2001-11-19
IL144155A0 (en) 2002-05-23
PL188447B1 (pl) 2005-02-28
ES2172697T3 (es) 2002-10-01
AP9801252A0 (en) 1998-06-30
IL124663A (en) 2001-10-31
EP0970074B1 (en) 2002-03-20

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