MX9801147A - Compuestos parasiticidas. - Google Patents

Compuestos parasiticidas.

Info

Publication number
MX9801147A
MX9801147A MX9801147A MX9801147A MX9801147A MX 9801147 A MX9801147 A MX 9801147A MX 9801147 A MX9801147 A MX 9801147A MX 9801147 A MX9801147 A MX 9801147A MX 9801147 A MX9801147 A MX 9801147A
Authority
MX
Mexico
Prior art keywords
halogen
optionally substituted
alkyl
phenyl
alkoxycarbonyl
Prior art date
Application number
MX9801147A
Other languages
English (en)
Inventor
Bernard Joseph Banks
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9516454.7A external-priority patent/GB9516454D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of MX9801147A publication Critical patent/MX9801147A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/561,2-Diazoles; Hydrogenated 1,2-diazoles
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/02Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18One oxygen or sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38Nitrogen atoms
    • C07D231/40Acylated on said nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Derivados de pirazol parasiticidas de formula I (Ver Formula) en la que R1 representa CN, alcoxicarbonilo C1-6, NO2, CHO, alcanoilo C1-6, fenilo sustituido opcionalmente por uno o más halogenos, o alquilo C1-6 sustituido opcionalmente por uno o más halogenos; R2 representa un grupo de formula II, III, IV, (Ver Formula) en las que R7 representa H, halogeno, carbamoilo, ciano, trialquilsililo C1-6, alquilo C1-6 (sustituido opcionalmente por uno o más halogenos, OH o alcoxilo C1-6), alcoxicarbonilo C1-6, fenilo o un anillo heterociclo de 5 o 6 miembros que está saturado o parcial o completamente insaturado y contiene hasta cuatro heteroátomos seleccionados de forma independiente de entre hasta 4 átomos de N, hasta 2 átomos de O y hasta dos átomos de 8 y que está unido al radical alquinilo por un átomo C, S o N disponible cuando la valencia lo permita; y R8, R9 y R10 representan cada uno de forma independiente H, halogeno, fenilo sustituido opcionalmente por uno o más halogenos, CN o alquilo C1-6 sustituido opcionalmente por uno o más halogenos; R3 representa H, alquilo C1-6, halogeno, NH2, NH(alcanoilo C1-6), NH(alcoxicarbonilo C1-6), N(alcoxicarbonilo C1-6)2, NH(alquilo C1-6), N(alquilo C1-6)2, NHCONH(alquilo C1-6), n-pirrolilo, NHCONH(fenilo sustituido opcionalmente por uno o más halogenos), N=CH(FENILO), OH, alcoxilo C1-6, SH o S(O)n(alquilo C1-6 sustituido opcionalmente por uno o más halogenos) donde n es 0, 1 o 2; y R4, R5 y R6 representan cada uno de forma independiente H, halogenos, alcoxilo C1-6 sustituido opcionalmente por uno o más halogenos, S(O)n(alquilo C1-6 sustituido opcionalmente pro uno o más halogenos) donde n es 0, 1 o 2. o CH2CO, CN, CONH2, CSNH2, OCF3 o SF5; o una sal veterinaria o farmacéuticamente aceptable del mismo.
MX9801147A 1995-08-11 1996-08-05 Compuestos parasiticidas. MX9801147A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9516454.7A GB9516454D0 (en) 1995-08-11 1995-08-11 Parasiticidal compounds
GBGB9601128.3A GB9601128D0 (en) 1995-08-11 1996-01-19 Parasiticidal compounds
PCT/EP1996/003501 WO1997007102A1 (en) 1995-08-11 1996-08-05 Parasiticidal compounds

Publications (1)

Publication Number Publication Date
MX9801147A true MX9801147A (es) 1998-05-31

Family

ID=26307556

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9801147A MX9801147A (es) 1995-08-11 1996-08-05 Compuestos parasiticidas.

Country Status (26)

Country Link
US (1) US6255333B1 (es)
EP (1) EP0871617B1 (es)
JP (1) JP3154413B2 (es)
KR (1) KR100310571B1 (es)
CN (1) CN1159298C (es)
AR (1) AR003976A1 (es)
AT (1) ATE208762T1 (es)
AU (1) AU710736B2 (es)
BR (1) BR9610608A (es)
CA (1) CA2229173C (es)
CO (1) CO4480737A1 (es)
CZ (1) CZ292275B6 (es)
DE (1) DE69617041T2 (es)
DK (1) DK0871617T3 (es)
ES (1) ES2165520T3 (es)
GB (1) GB9601128D0 (es)
HU (1) HUP9802865A3 (es)
IL (1) IL122281A (es)
MX (1) MX9801147A (es)
NO (1) NO310459B1 (es)
NZ (1) NZ316473A (es)
PL (1) PL185765B1 (es)
PT (1) PT871617E (es)
RU (1) RU2151766C1 (es)
TW (1) TW381082B (es)
WO (1) WO1997007102A1 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997028126A1 (en) * 1996-01-30 1997-08-07 Takeda Chemical Industries, Ltd. Arylpyrazole insecticides
TW524667B (en) * 1996-12-05 2003-03-21 Pfizer Parasiticidal pyrazoles
GB9801851D0 (en) * 1998-01-29 1998-03-25 Pfizer Ltd Parasiticidal agents
GB9810354D0 (en) * 1998-05-14 1998-07-15 Pfizer Ltd Heterocycles
GB9811050D0 (en) * 1998-05-22 1998-07-22 Pfizer Ltd Pyrazoles
AR021608A1 (es) * 1998-12-11 2002-07-31 Merial Ltd Represion de artropodos en animales
US6531501B1 (en) 1998-12-11 2003-03-11 Aventis Cropscience, S.A. Control of arthropods in animals
GB9916052D0 (en) * 1999-07-08 1999-09-08 Pfizer Ltd Anthelmintic compositions
CN1096267C (zh) * 1999-08-19 2002-12-18 李春生 一种治疗鸡住白细胞原虫药物
JP2003516941A (ja) 1999-12-02 2003-05-20 アベンティス クロップサイエンス ソシエテ アノニム 動物における節足動物の制御
AU4589701A (en) 2000-03-24 2001-10-08 Cocensys Inc Aryl substituted pyrazoles, triazoles and tetrazoles, and the use thereof
SI1483245T1 (sl) * 2002-03-05 2007-02-28 Merial Ltd 5-substituirani alkilaminopirazolni derivati kot pesticidi
US6663876B2 (en) 2002-04-29 2003-12-16 Piedmont Pharmaceuticals, Llc Methods and compositions for treating ectoparasite infestation
AR040082A1 (es) * 2002-05-22 2005-03-16 Novartis Ag Derivados de n-acilaminoacetonitrilo y su uso para el control de parasitos
DE10300124A1 (de) * 2003-01-07 2004-07-15 Bayer Ag Verfahren zur Herstellung von Arylalkinen
CH697574B1 (de) * 2003-01-07 2008-12-15 Lanxess Deutschland Gmbh Pyrazolylarylalkine.
US7514464B2 (en) * 2003-12-18 2009-04-07 Pfizer Limited Substituted arylpyrazoles
GB0329314D0 (en) 2003-12-18 2004-01-21 Pfizer Ltd Substituted arylpyrazoles
GB0413970D0 (en) * 2004-06-22 2004-07-28 Syngenta Participations Ag Chemical compounds
ES2341974T3 (es) * 2004-06-26 2010-06-30 Merial Limited Derivados de 1-arilpirazol como agentes pesticidas.
US20080146643A1 (en) * 2005-06-15 2008-06-19 Pfizer Limited Combination
WO2006134459A1 (en) * 2005-06-15 2006-12-21 Pfizer Limited Substituted arylpyrazoles
US20080176865A1 (en) * 2005-06-15 2008-07-24 Pfizer Limited Substituted arylpyrazoles
KR20080016648A (ko) 2005-06-15 2008-02-21 화이자 리미티드 기생충 방제용 치환된 아릴피라졸
US7645786B2 (en) 2005-06-15 2010-01-12 Pfizer Inc. Substituted arylpyrazoles
US9447042B2 (en) * 2011-03-02 2016-09-20 The University Of Tokyo Endoparasite control agent
CN103613543B (zh) * 2013-11-05 2015-09-02 温州大学 一种氟虫腈衍生物的制备方法
US10941132B2 (en) * 2016-01-05 2021-03-09 Hua Medicine (Shanghai) Ltd. Pyrazole derivatives
CN105541821B (zh) * 2016-01-28 2018-05-18 中南民族大学 噁嗪酮化芳基吡唑型化合物及其超声波辐射合成方法和应用
KR101691604B1 (ko) 2016-03-29 2017-01-02 주식회사 한일라바테크 양변기용 패킹 슬리브

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GB8531485D0 (en) * 1985-12-20 1986-02-05 May & Baker Ltd Compositions of matter
US5547974A (en) * 1985-12-20 1996-08-20 Rhone-Poulenc Agriculture Ltd. Derivatives of N-phenylpyrazoles
US5091378A (en) * 1987-05-22 1992-02-25 E. R. Squibb & Sons, Inc. Phosphorus-containing HMG-CoA reductase inhibitors, new intermediates and method
DE69408950T2 (de) 1993-12-14 1998-10-15 Mitsubishi Chem Corp N-Pyrazolylcarbamatderivate und Fungizide für Landwirtschaft und Gartenbau, die diese als aktive Bestandteile erhalten, Produktion und Zwischenprodukte

Also Published As

Publication number Publication date
NO310459B1 (no) 2001-07-09
AU710736B2 (en) 1999-09-30
CZ39298A3 (cs) 1999-01-13
IL122281A0 (en) 1998-04-05
KR100310571B1 (ko) 2002-02-19
CN1192735A (zh) 1998-09-09
US6255333B1 (en) 2001-07-03
AR003976A1 (es) 1998-09-30
HUP9802865A3 (en) 2000-11-28
EP0871617B1 (en) 2001-11-14
DE69617041T2 (de) 2002-03-28
WO1997007102A1 (en) 1997-02-27
JP3154413B2 (ja) 2001-04-09
CA2229173A1 (en) 1997-02-27
EP0871617A1 (en) 1998-10-21
BR9610608A (pt) 1999-02-17
IL122281A (en) 2002-11-10
TW381082B (en) 2000-02-01
NO980570D0 (no) 1998-02-10
PL324995A1 (en) 1998-07-06
CZ292275B6 (cs) 2003-08-13
PT871617E (pt) 2002-02-28
JPH10510551A (ja) 1998-10-13
DK0871617T3 (da) 2002-03-25
ES2165520T3 (es) 2002-03-16
NZ316473A (en) 1999-04-29
ATE208762T1 (de) 2001-11-15
DE69617041D1 (de) 2001-12-20
GB9601128D0 (en) 1996-03-20
AU6871296A (en) 1997-03-12
HUP9802865A2 (hu) 1999-03-29
PL185765B1 (pl) 2003-07-31
KR19990036255A (ko) 1999-05-25
CO4480737A1 (es) 1997-07-09
NO980570L (no) 1998-03-31
CA2229173C (en) 2002-07-02
RU2151766C1 (ru) 2000-06-27
CN1159298C (zh) 2004-07-28

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