MX9703921A - 1-naftoilguanidinas sustituidas, procedimiento para su preparacion, su empleo como medicamento o agente de diagnostico, asi como medicamento que las contiene. - Google Patents

1-naftoilguanidinas sustituidas, procedimiento para su preparacion, su empleo como medicamento o agente de diagnostico, asi como medicamento que las contiene.

Info

Publication number
MX9703921A
MX9703921A MX9703921A MX9703921A MX9703921A MX 9703921 A MX9703921 A MX 9703921A MX 9703921 A MX9703921 A MX 9703921A MX 9703921 A MX9703921 A MX 9703921A MX 9703921 A MX9703921 A MX 9703921A
Authority
MX
Mexico
Prior art keywords
medicament
naphthoylguanidines
substituted
well
employment
Prior art date
Application number
MX9703921A
Other languages
English (en)
Other versions
MXPA97003921A (es
Inventor
Joachim Brendel
Heinz-Werner Kleemann
Heinrich Christian Englert
Hans Jochen Lang
Udo Albus
Bansi Lal
Anil Vasantrao Ghate
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of MX9703921A publication Critical patent/MX9703921A/es
Publication of MXPA97003921A publication Critical patent/MXPA97003921A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

La invencion se refiere a 1-naftoilguanidinas sustituidas de la formula I (Ver Formula); en la que R2 a R8 tienen los significados indicados en las reivindicaciones, son adecuados, como consecuencia como medicamentos antiarrítmicos con un componente cardioprotector para la profilaxis del infarto y el tratamiento del infarto, así como para el tratamiento de la angina de pecho. Inhiben también de forma preventiva los procesos patofisiologicos en la aparicion de lesiones inducidas por isquemias, en particular en el desencadenamiento de arritmias del corazon inducidas por isquemias.
MXPA/A/1997/003921A 1996-05-29 1997-05-28 1-naftoilguanidinas sustituidas, procedimiento para su preparacion, su empleo como medicamento o agente de diagnostico, asi como medicamento que las contiene MXPA97003921A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19621482.3 1996-05-29
DE19621482A DE19621482A1 (de) 1996-05-29 1996-05-29 Substituierte 1-Naphthoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (2)

Publication Number Publication Date
MX9703921A true MX9703921A (es) 1997-11-29
MXPA97003921A MXPA97003921A (es) 1998-07-03

Family

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Also Published As

Publication number Publication date
NO308528B1 (no) 2000-09-25
SK66997A3 (en) 1997-12-10
CA2206362A1 (en) 1997-11-29
SI0810205T1 (es) 2001-06-30
JP4039587B2 (ja) 2008-01-30
TR199700427A2 (xx) 1997-12-21
CN1167758A (zh) 1997-12-17
DE59703220D1 (de) 2001-05-03
TW372955B (en) 1999-11-01
BR9703342A (pt) 1998-08-18
NZ314914A (en) 1998-02-26
HUP9700954A2 (hu) 1998-03-02
AU710258B2 (en) 1999-09-16
CA2206362C (en) 2007-11-20
IL120925A0 (en) 1997-09-30
ES2155223T3 (es) 2001-05-01
NO972434D0 (no) 1997-05-28
CZ292441B6 (cs) 2003-09-17
ATE200076T1 (de) 2001-04-15
CN1062859C (zh) 2001-03-07
PT810205E (pt) 2001-08-30
GR3035811T3 (en) 2001-07-31
US6600072B2 (en) 2003-07-29
NO972434L (no) 1997-12-01
PL185755B1 (pl) 2003-07-31
SK282356B6 (sk) 2002-01-07
EP0810205B1 (de) 2001-03-28
HU9700954D0 (en) 1997-07-28
DE19621482A1 (de) 1997-12-04
AU2371397A (en) 1997-12-04
HRP970294A2 (en) 1998-04-30
CZ163197A3 (cs) 1998-06-17
HRP970294B1 (en) 2002-02-28
JPH1081663A (ja) 1998-03-31
ID17348A (id) 1997-12-24
PL318724A1 (en) 1997-12-08
RU2182901C2 (ru) 2002-05-27
ZA974664B (en) 1997-12-01
US20030013760A1 (en) 2003-01-16
DK0810205T3 (da) 2001-07-16
KR970074753A (ko) 1997-12-10
EP0810205A1 (de) 1997-12-03
AR007299A1 (es) 1999-10-27
HUP9700954A3 (en) 1998-04-28

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