MX9703244A - Expresion de lactoferrina recombinante procesada yfragmentos del polipeptido lactoferrina a partir de un producto de fusion en aspergillus. - Google Patents

Expresion de lactoferrina recombinante procesada yfragmentos del polipeptido lactoferrina a partir de un producto de fusion en aspergillus.

Info

Publication number
MX9703244A
MX9703244A MX9703244A MX9703244A MX9703244A MX 9703244 A MX9703244 A MX 9703244A MX 9703244 A MX9703244 A MX 9703244A MX 9703244 A MX9703244 A MX 9703244A MX 9703244 A MX9703244 A MX 9703244A
Authority
MX
Mexico
Prior art keywords
lactoferrin
aspergillus
polypeptide
ragments
expression
Prior art date
Application number
MX9703244A
Other languages
English (en)
Spanish (es)
Inventor
Orla M Conneely
Denis R Headon
Bert W O'malley
Original Assignee
Agennix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agennix Inc filed Critical Agennix Inc
Publication of MX9703244A publication Critical patent/MX9703244A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MX9703244A 1994-11-02 1997-05-02 Expresion de lactoferrina recombinante procesada yfragmentos del polipeptido lactoferrina a partir de un producto de fusion en aspergillus. MX9703244A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/303,009 US5571697A (en) 1989-05-05 1994-11-02 Expression of processed recombinant lactoferrin and lactoferrin polypeptide fragments from a fusion product in Aspergillus

Publications (1)

Publication Number Publication Date
MX9703244A true MX9703244A (es) 1998-07-31

Family

ID=23170177

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9703244A MX9703244A (es) 1994-11-02 1997-05-02 Expresion de lactoferrina recombinante procesada yfragmentos del polipeptido lactoferrina a partir de un producto de fusion en aspergillus.

Country Status (11)

Country Link
US (3) US5571697A (show.php)
EP (1) EP0871724A1 (show.php)
JP (1) JPH10509317A (show.php)
KR (1) KR100443307B1 (show.php)
CN (1) CN1230537C (show.php)
AU (1) AU4279896A (show.php)
CA (1) CA2204246A1 (show.php)
DE (1) DE871724T1 (show.php)
ES (1) ES2127164T1 (show.php)
MX (1) MX9703244A (show.php)
WO (1) WO1996014413A1 (show.php)

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US6111081A (en) * 1996-05-31 2000-08-29 Baylor College Of Medicine Lactoferrin variants and uses thereof
US7883872B2 (en) * 1996-10-10 2011-02-08 Dyadic International (Usa), Inc. Construction of highly efficient cellulase compositions for enzymatic hydrolysis of cellulose
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US7323443B2 (en) * 2002-12-12 2008-01-29 Agennix Inc. Lactoferrin in the reduction of pain
WO2004103285A2 (en) * 2003-05-14 2004-12-02 Agennix Incorporated Lactoferrin in the treatment of diabetes mellitus
AU2004289170B2 (en) * 2003-06-06 2009-12-17 Agennix Incorporated Lactoferrin as an adjuvant in cancer vaccines
US20040259770A1 (en) * 2003-06-19 2004-12-23 Rush University Medical Center Method for determining leukocyte activation
US20050075277A1 (en) * 2003-07-10 2005-04-07 Agennix Incorporated Use of lactoferrin in prophylaxis against infection and/or inflammation in immunosuppressed subjects
BRPI0413833A (pt) 2003-09-11 2006-10-24 Novozymes As célula hospedeira microbiana recombinante, construção de ácido nucleico, método para produzir uma enzima e/ou um agente antimicrobiano, produto de fusão, aditivo e composição de ração animal, animal não humano transgênico ou produtos ou elementos deste, usos do produto de fusão, da co-expressão de um agente antimicrobiano e uma enzima, e de um peptìdeo de proteção, e, método para identificar um peptìdeo de proteção
WO2005035569A2 (en) * 2003-10-10 2005-04-21 Five Prime Therapeutics, Inc. Kiaa0779, splice variants thereof, and methods of their use
JP2007517504A (ja) * 2003-12-09 2007-07-05 ベントリア バイオサイエンス 融合担体として種子貯蔵蛋白を利用する植物種子中の融合ポリペプチドの高水準発現
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JP4634809B2 (ja) * 2005-01-05 2011-02-16 株式会社アップウェル アポタンパク質の製造方法
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WO2009033071A2 (en) * 2007-09-07 2009-03-12 Dyadic International, Inc. Novel fungal enzymes
WO2010112988A1 (en) * 2009-01-28 2010-10-07 Jean-Paul Perraudin Method for production of lactoferrin
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WO2010121933A1 (en) * 2009-04-22 2010-10-28 Dsm Ip Assets B.V. Process for the production of a recombinant polypeptide of interest
EP2416800A1 (en) 2010-02-25 2012-02-15 Agennix AG Oral lactoferrin in the treatment of severe sepsis
JP6322576B2 (ja) * 2012-07-03 2018-05-09 花王株式会社 有用微生物および目的物質の製造方法
CN103421794B (zh) * 2013-08-08 2014-07-02 华南理工大学 一种黑曲霉组成型表达元件、表达载体、重组黑曲霉及其构建方法和应用
CN108893415B (zh) * 2018-07-31 2022-12-27 上海凯圣生物科技有限公司 曲霉菌株及利用曲霉菌株发酵生产人乳铁蛋白的方法
CN119948159A (zh) * 2022-09-15 2025-05-06 诺维信公司 真菌信号肽
WO2025157268A1 (zh) * 2024-01-24 2025-07-31 南京百斯杰生物工程有限公司 一种米曲霉重组菌株的构建方法
WO2025226596A1 (en) * 2024-04-24 2025-10-30 Novozymes A/S Methods for producing secreted polypeptides
CN119776443B (zh) * 2024-12-23 2025-12-02 江苏创健医疗科技股份有限公司 一种多拷贝整合实现高效合成人乳铁蛋白的方法与应用
CN119841906B (zh) * 2025-01-26 2025-09-26 新苡萃(上海)生物科技有限公司 一种淀粉酶信号肽变体及其应用
JP7864404B1 (ja) * 2025-08-27 2026-05-25 大関株式会社 糸状菌用プロモーターのエンハンサーおよびその利用

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Also Published As

Publication number Publication date
CN1171815A (zh) 1998-01-28
US5955316A (en) 1999-09-21
DE871724T1 (de) 1999-06-02
KR970707283A (ko) 1997-12-01
EP0871724A1 (en) 1998-10-21
US6080559A (en) 2000-06-27
CA2204246A1 (en) 1996-05-17
WO1996014413A1 (en) 1996-05-17
AU4279896A (en) 1996-05-31
KR100443307B1 (ko) 2004-11-08
US5571697A (en) 1996-11-05
JPH10509317A (ja) 1998-09-14
ES2127164T1 (es) 1999-04-16
EP0871724A4 (show.php) 1998-10-21
CN1230537C (zh) 2005-12-07

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