MX9304868A - 27-hidroxirapamicina, derivados de la misma y composicion farmaceutica que la contiene. - Google Patents

27-hidroxirapamicina, derivados de la misma y composicion farmaceutica que la contiene.

Info

Publication number
MX9304868A
MX9304868A MX9304868A MX9304868A MX9304868A MX 9304868 A MX9304868 A MX 9304868A MX 9304868 A MX9304868 A MX 9304868A MX 9304868 A MX9304868 A MX 9304868A MX 9304868 A MX9304868 A MX 9304868A
Authority
MX
Mexico
Prior art keywords
hydroxyrapamicine
derived
same
pharmaceutical composition
hydroxyrapamycin
Prior art date
Application number
MX9304868A
Other languages
English (en)
Spanish (es)
Inventor
Frances Christy Nelson
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/009,605 external-priority patent/US5256790A/en
Application filed by American Home Prod filed Critical American Home Prod
Publication of MX9304868A publication Critical patent/MX9304868A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
MX9304868A 1992-08-13 1993-08-11 27-hidroxirapamicina, derivados de la misma y composicion farmaceutica que la contiene. MX9304868A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93012492A 1992-08-13 1992-08-13
US08/009,605 US5256790A (en) 1992-08-13 1993-01-27 27-hydroxyrapamycin and derivatives thereof

Publications (1)

Publication Number Publication Date
MX9304868A true MX9304868A (es) 1994-05-31

Family

ID=26679675

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9304868A MX9304868A (es) 1992-08-13 1993-08-11 27-hidroxirapamicina, derivados de la misma y composicion farmaceutica que la contiene.

Country Status (12)

Country Link
EP (1) EP0655065B1 (enFirst)
JP (1) JPH08501084A (enFirst)
AT (1) ATE146179T1 (enFirst)
AU (1) AU5007193A (enFirst)
CA (1) CA2142288A1 (enFirst)
DE (1) DE69306585T2 (enFirst)
DK (1) DK0655065T3 (enFirst)
ES (1) ES2096941T3 (enFirst)
GR (1) GR3022730T3 (enFirst)
HU (1) HU221499B (enFirst)
MX (1) MX9304868A (enFirst)
WO (1) WO1994004540A1 (enFirst)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527907A (en) * 1993-11-19 1996-06-18 Abbott Laboratories Macrolide immunomodulators
EP0729471A1 (en) * 1993-11-19 1996-09-04 Abbott Laboratories Semisynthetic analogs of rapamycin (macrolides) being immunomodulators
US6187757B1 (en) 1995-06-07 2001-02-13 Ariad Pharmaceuticals, Inc. Regulation of biological events using novel compounds
DE69624921T2 (de) 1995-06-09 2003-09-11 Novartis Ag, Basel Rapamycinderivate
IL147803A0 (en) 1999-08-24 2002-08-14 Ariad Gene Therapeutics Inc 28-epirapalogs
US7067526B1 (en) 1999-08-24 2006-06-27 Ariad Gene Therapeutics, Inc. 28-epirapalogs
EP1478648B1 (en) 2002-02-01 2014-04-30 ARIAD Pharmaceuticals, Inc. Phosphorus-containing compounds and uses thereof
WO2004060346A2 (en) 2002-12-30 2004-07-22 Angiotech International Ag Drug delivery from rapid gelling polymer composition
EP1768662A2 (en) 2004-06-24 2007-04-04 Novartis Vaccines and Diagnostics, Inc. Small molecule immunopotentiators and assays for their detection
CA2669415A1 (en) 2006-11-14 2008-05-22 Ariad Pharmaceuticals, Inc. Solid dosage form comprising ap23573
EP2245165A4 (en) 2008-01-11 2011-06-01 Massachusetts Eye & Ear Infirm TRANSGENIC CONDITIONAL STOP DIMERICABLE CASPASE ANIMALS
CN105283553B (zh) 2013-06-11 2021-06-25 克隆技术实验室有限公司 蛋白质富集的微泡及其制备和使用方法
PL3788049T3 (pl) 2018-05-01 2023-06-19 Revolution Medicines, Inc. Połączone z C40, C28 i C32 analogi rapamycyny jako inhibitory mTOR
EP3788050B1 (en) 2018-05-01 2024-08-28 Revolution Medicines, Inc. C26-linked rapamycin analogs as mtor inhibitors
AU2022253019A1 (en) * 2021-04-09 2023-11-16 Revolution Medicines, Inc. Synthesis of rapamycin analog compounds
EP4531859A4 (en) 2022-05-25 2026-05-27 Revolution Medicines Inc CANCER TREATMENT METHODS USING AN MTOR INHIBITOR

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04230389A (ja) * 1990-07-16 1992-08-19 American Home Prod Corp ラパマイシン誘導体
US5102876A (en) * 1991-05-07 1992-04-07 American Home Products Corporation Reduction products of rapamycin

Also Published As

Publication number Publication date
GR3022730T3 (en) 1997-06-30
DE69306585D1 (de) 1997-01-23
ATE146179T1 (de) 1996-12-15
WO1994004540A1 (en) 1994-03-03
AU5007193A (en) 1994-03-15
HU221499B (en) 2002-10-28
JPH08501084A (ja) 1996-02-06
CA2142288A1 (en) 1994-03-03
DK0655065T3 (enFirst) 1997-02-24
HUT71614A (en) 1996-01-29
HU9500432D0 (en) 1995-04-28
ES2096941T3 (es) 1997-03-16
EP0655065A1 (en) 1995-05-31
EP0655065B1 (en) 1996-12-11
DE69306585T2 (de) 1997-04-17

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Legal Events

Date Code Title Description
FG Grant or registration
HC Change of company name or juridical status

Owner name: SILGAN TUBES CORPORATION

MM Annulment or lapse due to non-payment of fees