GR3022730T3 - 27-hydroxyrapamycin and derivatives thereof. - Google Patents
27-hydroxyrapamycin and derivatives thereof.Info
- Publication number
- GR3022730T3 GR3022730T3 GR970400422T GR970400422T GR3022730T3 GR 3022730 T3 GR3022730 T3 GR 3022730T3 GR 970400422 T GR970400422 T GR 970400422T GR 970400422 T GR970400422 T GR 970400422T GR 3022730 T3 GR3022730 T3 GR 3022730T3
- Authority
- GR
- Greece
- Prior art keywords
- hydroxyrapamycin
- derivatives
- formula
- compound
- deoxo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Transplantation (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US93012492A | 1992-08-13 | 1992-08-13 | |
US08/009,605 US5256790A (en) | 1992-08-13 | 1993-01-27 | 27-hydroxyrapamycin and derivatives thereof |
PCT/US1993/007581 WO1994004540A1 (en) | 1992-08-13 | 1993-08-12 | 27-hydroxyrapamycin and derivatives thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
GR3022730T3 true GR3022730T3 (en) | 1997-06-30 |
Family
ID=26679675
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR970400422T GR3022730T3 (en) | 1992-08-13 | 1997-03-03 | 27-hydroxyrapamycin and derivatives thereof. |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0655065B1 (el) |
JP (1) | JPH08501084A (el) |
AT (1) | ATE146179T1 (el) |
AU (1) | AU5007193A (el) |
CA (1) | CA2142288A1 (el) |
DE (1) | DE69306585T2 (el) |
DK (1) | DK0655065T3 (el) |
ES (1) | ES2096941T3 (el) |
GR (1) | GR3022730T3 (el) |
HU (1) | HU221499B (el) |
MX (1) | MX9304868A (el) |
WO (1) | WO1994004540A1 (el) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5527907A (en) * | 1993-11-19 | 1996-06-18 | Abbott Laboratories | Macrolide immunomodulators |
CA2175215C (en) * | 1993-11-19 | 2008-06-03 | Yat Sun Or | Semisynthetic analogs of rapamycin (macrolides) being immunomodulators |
US6187757B1 (en) | 1995-06-07 | 2001-02-13 | Ariad Pharmaceuticals, Inc. | Regulation of biological events using novel compounds |
RU2158267C2 (ru) * | 1995-06-09 | 2000-10-27 | Новартис Аг | Производные рапамицина и фармацевтическая композиция на их основе |
WO2001014387A1 (en) | 1999-08-24 | 2001-03-01 | Ariad Gene Therapeutics, Inc. | 28-epirapalogs |
US7067526B1 (en) | 1999-08-24 | 2006-06-27 | Ariad Gene Therapeutics, Inc. | 28-epirapalogs |
EP2407473A3 (en) | 2002-02-01 | 2012-03-21 | ARIAD Pharmaceuticals, Inc | Method for producing phosphorus-containing compounds |
AU2003300076C1 (en) | 2002-12-30 | 2010-03-04 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
WO2006115509A2 (en) | 2004-06-24 | 2006-11-02 | Novartis Vaccines And Diagnostics Inc. | Small molecule immunopotentiators and assays for their detection |
EP2094241A4 (en) | 2006-11-14 | 2013-04-17 | Ariad Pharma Inc | ORAL FORMULATIONS |
WO2009089549A1 (en) | 2008-01-11 | 2009-07-16 | Massachusetts Eye & Ear Infirmary | Conditional-stop dimerizable caspase transgenic animals |
WO2014200659A1 (en) | 2013-06-11 | 2014-12-18 | Clontech Laboratories, Inc. | Protein enriched microvesicles and methods of making and using the same |
CN112368289B (zh) | 2018-05-01 | 2024-02-20 | 锐新医药公司 | 作为mtor抑制剂的c26-连接的雷帕霉素类似物 |
KR20240006537A (ko) * | 2021-04-09 | 2024-01-15 | 레볼루션 메디슨즈, 인크. | 라파마이신 유사체 화합물의 합성 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04230389A (ja) * | 1990-07-16 | 1992-08-19 | American Home Prod Corp | ラパマイシン誘導体 |
US5102876A (en) * | 1991-05-07 | 1992-04-07 | American Home Products Corporation | Reduction products of rapamycin |
-
1993
- 1993-08-11 MX MX9304868A patent/MX9304868A/es not_active IP Right Cessation
- 1993-08-12 ES ES93919994T patent/ES2096941T3/es not_active Expired - Lifetime
- 1993-08-12 CA CA002142288A patent/CA2142288A1/en not_active Abandoned
- 1993-08-12 HU HU9500432A patent/HU221499B/hu not_active IP Right Cessation
- 1993-08-12 DK DK93919994.9T patent/DK0655065T3/da active
- 1993-08-12 AT AT93919994T patent/ATE146179T1/de not_active IP Right Cessation
- 1993-08-12 DE DE69306585T patent/DE69306585T2/de not_active Expired - Fee Related
- 1993-08-12 WO PCT/US1993/007581 patent/WO1994004540A1/en active IP Right Grant
- 1993-08-12 JP JP6506398A patent/JPH08501084A/ja active Pending
- 1993-08-12 AU AU50071/93A patent/AU5007193A/en not_active Abandoned
- 1993-08-12 EP EP93919994A patent/EP0655065B1/en not_active Expired - Lifetime
-
1997
- 1997-03-03 GR GR970400422T patent/GR3022730T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
WO1994004540A1 (en) | 1994-03-03 |
ATE146179T1 (de) | 1996-12-15 |
HUT71614A (en) | 1996-01-29 |
EP0655065B1 (en) | 1996-12-11 |
DE69306585D1 (de) | 1997-01-23 |
EP0655065A1 (en) | 1995-05-31 |
ES2096941T3 (es) | 1997-03-16 |
JPH08501084A (ja) | 1996-02-06 |
AU5007193A (en) | 1994-03-15 |
CA2142288A1 (en) | 1994-03-03 |
DE69306585T2 (de) | 1997-04-17 |
HU221499B (en) | 2002-10-28 |
MX9304868A (es) | 1994-05-31 |
DK0655065T3 (el) | 1997-02-24 |
HU9500432D0 (en) | 1995-04-28 |
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