MX6233E - Procedimiento para preparar derivados de 4-(4-alquilo inferior-1-piperazinil)pirazol(3,4-b)(1,5)benzodiazepina - Google Patents

Procedimiento para preparar derivados de 4-(4-alquilo inferior-1-piperazinil)pirazol(3,4-b)(1,5)benzodiazepina

Info

Publication number
MX6233E
MX6233E MX809093U MX909380U MX6233E MX 6233 E MX6233 E MX 6233E MX 809093 U MX809093 U MX 809093U MX 909380 U MX909380 U MX 909380U MX 6233 E MX6233 E MX 6233E
Authority
MX
Mexico
Prior art keywords
benzodiazepine
piperazinyl
pyrazole
procedure
lower alkyl
Prior art date
Application number
MX809093U
Other languages
English (en)
Spanish (es)
Inventor
Jiban Kumar Chakrabarti
Terrence Michael Hotten
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of MX6233E publication Critical patent/MX6233E/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
MX809093U 1979-10-16 1980-10-13 Procedimiento para preparar derivados de 4-(4-alquilo inferior-1-piperazinil)pirazol(3,4-b)(1,5)benzodiazepina MX6233E (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7935846 1979-10-16

Publications (1)

Publication Number Publication Date
MX6233E true MX6233E (es) 1985-01-14

Family

ID=10508540

Family Applications (1)

Application Number Title Priority Date Filing Date
MX809093U MX6233E (es) 1979-10-16 1980-10-13 Procedimiento para preparar derivados de 4-(4-alquilo inferior-1-piperazinil)pirazol(3,4-b)(1,5)benzodiazepina

Country Status (33)

Country Link
US (3) US4404137A (en:Method)
EP (1) EP0027390B1 (en:Method)
JP (1) JPS5663987A (en:Method)
KR (2) KR850000471B1 (en:Method)
AR (2) AR228041A1 (en:Method)
AT (1) AT373889B (en:Method)
AU (1) AU538500B2 (en:Method)
BE (1) BE885729A (en:Method)
BG (2) BG35042A3 (en:Method)
CA (1) CA1159056A (en:Method)
CH (1) CH646700A5 (en:Method)
CS (1) CS244409B2 (en:Method)
DD (1) DD153692A5 (en:Method)
DE (1) DE3068706D1 (en:Method)
DK (1) DK437480A (en:Method)
ES (1) ES8106905A1 (en:Method)
FI (1) FI67550C (en:Method)
FR (1) FR2467851A1 (en:Method)
GB (1) GB8327127D0 (en:Method)
GR (1) GR70720B (en:Method)
HU (1) HU182213B (en:Method)
IE (1) IE50358B1 (en:Method)
IL (1) IL61264A (en:Method)
IT (1) IT1143047B (en:Method)
LU (1) LU82853A1 (en:Method)
MX (1) MX6233E (en:Method)
NZ (1) NZ195248A (en:Method)
PH (2) PH16288A (en:Method)
PL (2) PL126824B1 (en:Method)
PT (1) PT71913B (en:Method)
RO (2) RO81351B (en:Method)
YU (1) YU261580A (en:Method)
ZA (1) ZA806342B (en:Method)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4404137A (en) * 1979-10-16 1983-09-13 Lilly Industries Limited Pyrazolo [3,4-b][1,5]benzodiazepine compounds
US4431589A (en) * 1980-12-11 1984-02-14 Lilly House Benzodiazepine compounds and their use as pharmaceuticals
US4596799A (en) * 1985-01-29 1986-06-24 Ciba-Geigy Corporation 9H-pyrrolo[2,1-c]-1,2,4-triazolo[4,3-a][1,4]benzodiazepines
TW219896B (en:Method) * 1988-07-07 1994-02-01 Duphar Int Res
GB8819059D0 (en) * 1988-08-11 1988-09-14 Lilly Industries Ltd Benzodiazepine compounds & their use as pharmaceuticals
US5631250A (en) * 1995-03-24 1997-05-20 Eli Lilly And Company Process and solvate of 2-methyl-thieno-benzodiazepine
US5637584A (en) * 1995-03-24 1997-06-10 Eli Lilly And Company Solvate of olanzapine
US20050085463A1 (en) * 2003-01-23 2005-04-21 Weiner David M. Use of N-desmethylclozapine to treat human neuropsychiatric disease
US20050250767A1 (en) * 2003-01-23 2005-11-10 Weiner David M Use of N-desmethylclozapine to treat human neuropsychiatric disease
AU2004206931A1 (en) * 2003-01-23 2004-08-05 Acadia Pharmaceuticals Inc. Use of N-desmethylclozapine to treat human neuropsychiatric disease
JP2007534656A (ja) * 2003-12-22 2007-11-29 アカディア ファーマシューティカルズ，インコーポレーテッド ムスカリンアゴニストとしてのアミノ置換ジアリール［ａ，ｄ］シクロヘプテン類似体および精神神経疾患の治療方法
KR20070007888A (ko) * 2004-04-01 2007-01-16 아카디아 파마슈티칼스 인코포레이티드 결정질 ｎ-데스메틸클로자핀
WO2007053618A1 (en) * 2005-10-31 2007-05-10 Acadia Pharmaceuticals Inc. Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders
JP5438482B2 (ja) * 2009-12-03 2014-03-12 Ｊｕｋｉ株式会社 ミシン、ミシンの縫製データ編集装置及びミシンの縫製データ編集プログラム

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3450694A (en) * 1966-02-23 1969-06-17 Abbott Lab Substituted benzoxazepines and benzothiazepines
US3758479A (en) * 1967-03-22 1973-09-11 Sandoz Ag Nitro and sulphamoyl substituted dibenzodiazepines
DE1795183B1 (de) * 1968-08-20 1972-07-20 Thomae Gmbh Dr K 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel
CA918659A (en) * 1969-07-31 1973-01-09 Yoshitomi Pharmaceutical Industries 11-(4-substituted-1-piperazinyl)-dibenzo (b,f) (1,4) thiazepines
US4115568A (en) * 1974-11-26 1978-09-19 Lilly Industries Limited Thieno[3,2-b]-[1,5]benzodiazepines
US4172831A (en) * 1974-11-26 1979-10-30 Lilly Industries Limited Thieno-benzodiazepines
US3951981A (en) * 1975-02-24 1976-04-20 American Cyanamid Company Substituted benzodiazepines and method of use
US3953430A (en) * 1975-02-24 1976-04-27 American Cyanamid Company Substituted benzodiazepin-10-ones and method of use
DE2707269A1 (de) * 1977-02-19 1978-08-24 Hoechst Ag Heterocyclische stickstoffverbindungen und verfahren zu ihrer herstellung
DE2707270A1 (de) * 1977-02-19 1978-08-24 Hoechst Ag Pyrazolo-diazepine und verfahren zu ihrer herstellung
US4097597A (en) * 1977-02-23 1978-06-27 Abbott Laboratories Dibenzo b,e! 1,4!diazepines
IT7851496A0 (it) * 1977-10-31 1978-10-13 Sandoz Ag Menti pirazinobenzossazepine loro preparazione e loro impiego quali medica
CH643263A5 (de) * 1979-05-11 1984-05-30 Sandoz Ag Benzodiazepine, ihre herstellung und verwendung.
EP0023707B1 (de) * 1979-08-03 1986-04-30 Byk Gulden Lomberg Chemische Fabrik GmbH Substituierte Tetraazatricyclen, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende Arzneimittel
US4404137A (en) * 1979-10-16 1983-09-13 Lilly Industries Limited Pyrazolo [3,4-b][1,5]benzodiazepine compounds

Also Published As

Publication number Publication date
IL61264A (en) 1985-08-30
US4486591A (en) 1984-12-04
IT8049899A0 (it) 1980-10-14
FI67550B (fi) 1984-12-31
LU82853A1 (fr) 1982-05-10
RO81351A (ro) 1983-02-15
KR850000471B1 (ko) 1985-04-08
IT1143047B (it) 1986-10-22
IE802135L (en) 1981-04-16
ES495948A0 (es) 1981-09-16
BG34907A3 (en) 1983-12-15
FR2467851B1 (en:Method) 1985-04-05
DE3068706D1 (en) 1984-08-30
YU261580A (en) 1983-12-31
ES8106905A1 (es) 1981-09-16
ATA510180A (de) 1983-07-15
EP0027390B1 (en) 1984-07-25
IL61264A0 (en) 1980-12-31
AR228041A1 (es) 1983-01-14
CH646700A5 (fr) 1984-12-14
FR2467851A1 (fr) 1981-04-30
EP0027390A1 (en) 1981-04-22
DK437480A (da) 1981-04-17
PL227306A1 (en:Method) 1981-09-18
ZA806342B (en) 1982-05-26
HU182213B (en) 1983-12-28
CA1159056A (en) 1983-12-20
PH17759A (en) 1984-12-05
KR850000472B1 (ko) 1985-04-08
KR830004300A (ko) 1983-07-09
PL126824B1 (en) 1983-09-30
BG35042A3 (en) 1983-01-16
IE50358B1 (en) 1986-04-02
NZ195248A (en) 1983-11-18
AU538500B2 (en) 1984-08-16
AU6325280A (en) 1981-04-30
JPS5663987A (en) 1981-05-30
PT71913B (en) 1981-08-31
US4404137A (en) 1983-09-13
RO81351B (ro) 1983-02-28
AR228101A1 (es) 1983-01-14
FI803253L (fi) 1981-04-17
CS244409B2 (en) 1986-07-17
GB8327127D0 (en) 1983-11-09
PH16288A (en) 1983-09-05
KR850001463A (ko) 1985-03-18
US4542131A (en) 1985-09-17
GR70720B (en:Method) 1983-01-18
PT71913A (en) 1980-11-01
RO85822B (ro) 1984-11-30
DD153692A5 (de) 1982-01-27
BE885729A (fr) 1981-04-15
PL135044B1 (en) 1985-09-30
PL231270A1 (en:Method) 1981-12-23
FI67550C (fi) 1985-04-10
RO85822A (ro) 1984-11-25
AT373889B (de) 1984-02-27

Similar Documents

Publication Publication Date Title
AR225437A1 (es) Procedimiento para la produccion de derivados de 4-amino-1,2-dihidro-2-oxo-1,8-naftiridian
ES508618A0 (es) Procedimiento para la preparacion de derivados de la quino- lina.
ES487584A0 (es) Procedimiento para preparar nuevos derivados de pleuromuti- lin
MX6233E (es) Procedimiento para preparar derivados de 4-(4-alquilo inferior-1-piperazinil)pirazol(3,4-b)(1,5)benzodiazepina
ES508025A0 (es) "procedimiento para preparar derivados de dihidropiridina".
AR231447A1 (es) Procedimiento para preparar derivados de 4,5-dihidro-imidazo 1,2-a-quinazolin-2 1h-ona
ES497530A0 (es) Procedimiento para la preparacion de derivados de 2,3-indo- lediona
AR226715A1 (es) Procedimiento para preparar derivados de 5,11-dihidro-6h-pirido(2,3-b)(1,4)-benzodiazepin-6-ona
ES493931A0 (es) Procedimiento de preparacion de nuevos derivados de la 3,4,5-trimetoxi-cinamoil-piperazina
AR230631A1 (es) Procedimiento para preparar nuevos derivados de 5-(4,5-dihidro-3(2h)-piridazinon-6-il)-benzotriazol
ES490061A0 (es) Procedimiento para preparar nuevos derivados de (piridil-2)-2-tetrahidrotiofeno
ES495819A0 (es) Procedimiento de preparar derivados 1,2,4-oxadiazolin-5-oni-cos
AR229087A1 (es) Procedimiento para preparar derivados de 4-(substituido)tio-1-beta-d-ribofuranosilpirazolo(3,4-d)pirimidina
ES493927A0 (es) Procedimiento para la preparacion de derivados de 3-amino-1-benzoxepin-5(2h)-ona
ES491153A0 (es) Procedimiento de preparar derivados pirrolo(1,2-a)pirimidi- nicos
ES494286A0 (es) Procedimiento de preparacion de nuevos derivados 1,1,2-tri- fenilpropanos y -propenos
ES494211A0 (es) Procedimiento para la preparacion de nuevos derivados de 10-halogen-e-homo-eburnanos.
ES494480A0 (es) Procedimiento para preparar nuevos derivados de cefalospori-na
ES491010A0 (es) Procedimiento para la preparacion de derivados 17-beta de 4-diazo-5- alfa-androstan-3-onas
ES491004A0 (es) Procedimiento de preparacion de nuevos derivados halogenadosde isopropilamino-pirimidina
MX5725E (es) Procedimiento para la preparacion de derivados de 5,8-dihidrofuro-(3,2-b)-1,8-naftiridina
ES488862A0 (es) Procedimiento de preparacion de nuevos derivados pirido (3,4-e)-as-triazinos acilados y de sus sales de acicion aci-da de los mismos
ES493503A0 (es) Procedimiento de preparacion de nuevos derivados de 1-(1-(3,4-dimetoxi-fenil)-3-amino-propil)-6,7-dimetoxi-iso- quinoleina
NO151464C (no) Fremgangsmaate ved fremstilling av 9-hydrazono-6,7,8,9-tetrahydro-4h-pyrido(1,2-a)pyrimidin-4-on-derivater
MX12051A (es) Procedimiento para preparar nuevos derivados de la1-bencenosulfonil-2-oxo-5-alquiltio-pirrolidina.