MX392761B - Anticuerpos anti-influenza b neutralizantes y usos de los mismos. - Google Patents

Anticuerpos anti-influenza b neutralizantes y usos de los mismos.

Info

Publication number
MX392761B
MX392761B MX2017000595A MX2017000595A MX392761B MX 392761 B MX392761 B MX 392761B MX 2017000595 A MX2017000595 A MX 2017000595A MX 2017000595 A MX2017000595 A MX 2017000595A MX 392761 B MX392761 B MX 392761B
Authority
MX
Mexico
Prior art keywords
influenza
antibodies
virus
neutralizing anti
neutralizing
Prior art date
Application number
MX2017000595A
Other languages
English (en)
Spanish (es)
Other versions
MX2017000595A (es
Inventor
Andy Yuan
Antonio Lanzavecchia
Davide Corti
Ebony Benjamin
Josephine Mary Mcauliffe
Leslie Wachter
Nicole Kallewaard-Lelay
Qing Zhu
Original Assignee
Medimmune Llc
Humabs Biomed Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune Llc, Humabs Biomed Sa filed Critical Medimmune Llc
Publication of MX2017000595A publication Critical patent/MX2017000595A/es
Publication of MX392761B publication Critical patent/MX392761B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1018Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515Complete light chain, i.e. VL + CL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • G01N2333/11Orthomyxoviridae, e.g. influenza virus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/10Detection of antigens from microorganism in sample from host

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
MX2017000595A 2014-07-15 2015-07-14 Anticuerpos anti-influenza b neutralizantes y usos de los mismos. MX392761B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462024804P 2014-07-15 2014-07-15
PCT/US2015/040385 WO2016011035A2 (en) 2014-07-15 2015-07-14 Neutralizing anti-influenza b antibodies and uses thereof

Publications (2)

Publication Number Publication Date
MX2017000595A MX2017000595A (es) 2017-10-12
MX392761B true MX392761B (es) 2025-03-21

Family

ID=55079157

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2017000595A MX392761B (es) 2014-07-15 2015-07-14 Anticuerpos anti-influenza b neutralizantes y usos de los mismos.
MX2022006558A MX2022006558A (es) 2014-07-15 2017-01-13 Anticuerpos anti-influenza b neutralizantes y usos de los mismos.
MX2022006561A MX2022006561A (es) 2014-07-15 2017-01-13 Anticuerpos anti-influenza b neutralizantes y usos de los mismos.

Family Applications After (2)

Application Number Title Priority Date Filing Date
MX2022006558A MX2022006558A (es) 2014-07-15 2017-01-13 Anticuerpos anti-influenza b neutralizantes y usos de los mismos.
MX2022006561A MX2022006561A (es) 2014-07-15 2017-01-13 Anticuerpos anti-influenza b neutralizantes y usos de los mismos.

Country Status (10)

Country Link
US (6) US10294292B2 (OSRAM)
EP (1) EP3169407A4 (OSRAM)
JP (4) JP6837434B2 (OSRAM)
CN (4) CN106573154B (OSRAM)
AU (3) AU2015289805B2 (OSRAM)
BR (1) BR112017000640A2 (OSRAM)
CA (1) CA2954780A1 (OSRAM)
MX (3) MX392761B (OSRAM)
RU (2) RU2711932C2 (OSRAM)
WO (1) WO2016011035A2 (OSRAM)

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CN112048006B (zh) * 2020-09-08 2021-04-27 扬州大学 一种替代中和效力测定的elisa方法及其应用
EP4441091A4 (en) * 2021-11-30 2025-12-17 Sab Llc UNGULATE-DERIVED POLYCLONAL IMMUNE GLOBULIN SPECIFIC FOR INFLUENCE VAVIRUS AND USES THEREOF
CN118420751B (zh) * 2022-07-09 2025-04-08 东莞市朋志生物科技有限公司 抗乙型流感病毒抗体、检测乙型流感病毒的试剂和试剂盒

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Also Published As

Publication number Publication date
US20190233504A1 (en) 2019-08-01
US20200190169A1 (en) 2020-06-18
AU2015289805A1 (en) 2017-03-02
JP2021074013A (ja) 2021-05-20
CN113563462B (zh) 2024-08-13
AU2015289805B2 (en) 2020-06-25
CN113563462A (zh) 2021-10-29
AU2020233635A1 (en) 2020-10-08
US10519221B2 (en) 2019-12-31
BR112017000640A2 (pt) 2017-11-14
AU2024202231A1 (en) 2024-05-02
EP3169407A2 (en) 2017-05-24
WO2016011035A8 (en) 2016-12-08
RU2711932C2 (ru) 2020-01-23
JP7453430B2 (ja) 2024-03-19
US12325740B2 (en) 2025-06-10
US20220025020A1 (en) 2022-01-27
RU2020100073A (ru) 2020-03-03
MX2022006561A (es) 2022-07-11
CN113173990B (zh) 2024-10-29
RU2017104638A (ru) 2018-08-15
US20250263470A1 (en) 2025-08-21
EP3169407A4 (en) 2018-04-25
US10294292B2 (en) 2019-05-21
MX2017000595A (es) 2017-10-12
JP2024069341A (ja) 2024-05-21
US20170218054A1 (en) 2017-08-03
CN106573154A (zh) 2017-04-19
JP2017523805A (ja) 2017-08-24
US11787853B2 (en) 2023-10-17
CA2954780A1 (en) 2016-01-21
JP2023052268A (ja) 2023-04-11
US11174304B2 (en) 2021-11-16
RU2739952C2 (ru) 2020-12-30
JP7209754B2 (ja) 2023-01-20
CN106573154B (zh) 2021-06-15
CN119161468A (zh) 2024-12-20
RU2020100073A3 (OSRAM) 2020-06-10
AU2020233635B2 (en) 2024-01-18
JP6837434B2 (ja) 2021-03-03
CN113173990A (zh) 2021-07-27
WO2016011035A2 (en) 2016-01-21
RU2017104638A3 (OSRAM) 2019-07-17
US20240076357A1 (en) 2024-03-07
WO2016011035A3 (en) 2016-03-10
MX2022006558A (es) 2022-07-11

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